| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Müslüm Kuzu, Serkan Yıldırım, Fatih Mehmet Kandemir, Sefa Küçükler, Cüneyt Çağlayan, Erdinç Türk, Muhammet Bahaeddin Dörtbuda. Protective effect of morin on doxorubicin-induced hepatorenal toxicity in rats. Chemico-biological interactions. vol 308. 2019-07-22. PMID:31100273. |
liver and kidney tissue damage were determined both histopathologically and by serum alanine transaminase (alt), aspartate transaminase (ast), urea and creatinine analysis. |
2019-07-22 |
2023-08-13 |
rat |
| Yanhong Xiao, Long Chen, Yanfang Fan, Peng Yan, Suting Li, Xiaohui Zho. The effect of boletus polysaccharides on diabetic hepatopathy in rats. Chemico-biological interactions. vol 308. 2019-07-22. PMID:31100278. |
the blood glucose and lipid, alanine transaminase (alt) and aspartate transaminase (ast) were detected immediately. |
2019-07-22 |
2023-08-13 |
rat |
| Yu Wu, Wen-Jing Tian, Shuo Gao, Zu-Jian Liao, Guang-Hui Wang, Jir-Mehng Lo, Pei-Hsin Lin, De-Quan Zeng, Da-Ren Qiu, Xiang-Zhong Liu, Mi Zhou, Ting Lin, Hai-Feng Che. Secondary metabolites of petri-dish cultured Antrodia camphorata and their hepatoprotective activities against alcohol-induced liver injury in mice. Chinese journal of natural medicines. vol 17. issue 1. 2019-07-19. PMID:30704622. |
in mice alcohol-induced liver injury model, triglyceride (tg), aspartate aminotransferase (ast), alanine aminotransferase (alt), and malondialdehyde (mda) had been reduced by the pdca powder as well as the main content antcin k, which indicated that the pdca could protect alcoholic liver injury in mice model and antcin k could be the effective component responsible for the hepatoprotective activities of pdca against alcoholic liver diseases. |
2019-07-19 |
2023-08-13 |
mouse |
| Jie Cao, Xin Zhao, Ming-Jiang Liu, Hui Zheng, Jin-Gui L. [Protective effects of artesunate against Con A-induced autoimmune liver injury in mice]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 43. issue 10. 2019-07-17. PMID:29933681. |
the serum and liver tissue were collected for detecting the level of alanine aminotransferase (alt), and aspartate transaminase (ast), liver pathological histopathology, inflammatory cytokines and nuclear factor (nf-κb) key protein expression level. |
2019-07-17 |
2023-08-13 |
mouse |
| Maria Pokorska-Śpiewak, Aleksandra Stańska-Perka, Jolanta Popielska, Agnieszka Ołdakowska, Urszula Coupland, Konrad Zawadka, Małgorzata Szczepańska-Putz, Magdalena Marczyńsk. Prevalence and predictors of liver disease in HIV-infected children and adolescents. Scientific reports. vol 7. issue 1. 2019-07-16. PMID:28951598. |
liver disease was defined as an elevation of any of the following parameters: alanine or aspartate aminotransferase (alt and ast), total bilirubin, and gamma glutamyl transferase (ggtp). |
2019-07-16 |
2023-08-13 |
human |
| Qiongyin Fan, Baosheng Zhao, Chunguo Wang, Jingxuan Zhang, Jinying Wu, Ting Wang, Anlong X. Subchronic Toxicity Studies of Cortex Dictamni Extracts in Mice and Its Potential Hepatotoxicity Mechanisms in Vitro. Molecules (Basel, Switzerland). vol 23. issue 10. 2019-07-16. PMID:30274140. |
aspartate alanine aminotransferase (alt) and aminotransferase (ast) were significantly increased in the high-dose cdae and cdee groups compared to the control group. |
2019-07-16 |
2023-08-13 |
mouse |
| Sun Ha Jee, Minjoo Kim, Minkyung Kim, Hye Jin Yoo, Hyungyoon Kim, Keum Ji Jung, Seri Hong, Jong Ho Le. Metabolomics Profiles of Hepatocellular Carcinoma in a Korean Prospective Cohort: The Korean Cancer Prevention Study-II. Cancer prevention research (Philadelphia, Pa.). vol 11. issue 5. 2019-07-15. PMID:29500188. |
compared with the control group, the hcc group showed significantly higher serum levels of aspartate aminotransferase (ast), alanine aminotransferase, and γ-glutamyl transpeptidase. |
2019-07-15 |
2023-08-13 |
human |
| Guven Yenmis, Tugba Soydas, Hulya Arkan, Ertugrul Tasan, Gonul Kanigur Sultuybe. Genetic Variation in NFKB1 Gene Influences Liver Enzyme Levels in Morbidly Obese Women. Archives of Iranian medicine. vol 21. issue 1. 2019-07-15. PMID:29664665. |
the objective of our study was to investigate the relationship between nfkb1 gene variations and the risk of mo in the context of the high/normal level of liver enzymes such as alanine aminotransferase (alt), aspartate aminotransferase (ast), gamma-glutamyl transpeptidase (ggt), and alkaline phosphatase (alp). |
2019-07-15 |
2023-08-13 |
Not clear |
| Ya-Nan Jia, Ya-Lin Peng, Yi-Ping Zhao, Xi-Fei Cheng, You Zhou, Chun-Li Chai, Ling-Shu Zeng, Min-Hui Pan, Li X. Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs. Journal of agricultural and food chemistry. vol 67. issue 19. 2019-07-15. PMID:31012578. |
the results showed that treatment with oxy, res, and mula could significantly decreases the levels of alanine transaminase (alt) and aspartate transaminase (ast) ( p < 0.01). |
2019-07-15 |
2023-08-13 |
mouse |
| Guanhua Zhao, Xingyue Zhai, Min Qu, Changqing Tong, Wei L. Sulfated modification of the polysaccharides from Crassostrea gigas and their antioxidant and hepatoprotective activities through metabolomics analysis. International journal of biological macromolecules. vol 129. 2019-07-12. PMID:30753880. |
the study was further evaluated the hepatoprotective effect of scgp in alcoholic liver injury mice and determined total cholesterol (t-cho), low density lipoprotein cholesterol (ldl-c), total bilirubin (tbil), aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels of serum in mice. |
2019-07-12 |
2023-08-13 |
mouse |
| Mediline Goboza, Yapo G Aboua, Novel Chegou, Oluwafemi O Oguntibej. Vindoline effectively ameliorated diabetes-induced hepatotoxicity by docking oxidative stress, inflammation and hypertriglyceridemia in type 2 diabetes-induced male Wistar rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 112. 2019-07-10. PMID:30784928. |
vindoline significantly (p < 0.05) decreased diabetes-induced hepatic injury shown by decreased levels of serum alanine transferase (alt) (-42%), aspartate aminotransferase (ast) (-42%) and alkaline phosphatase (-62%) compared to the diabetic controls. |
2019-07-10 |
2023-08-13 |
rat |
| Sabine Szunerits, Vladyslav Mishyn, Iwona Grabowska, Rabah Boukherrou. Electrochemical cardiovascular platforms: Current state of the art and beyond. Biosensors & bioelectronics. vol 131. 2019-07-10. PMID:30851492. |
early biomarker assessments have involved testing for the total enzyme activity of aspartate aminotransferase (ast), lactate dehydrogenase (ldh) and creatine kinase (ck), which cardiac troponins being the main accepted biomarkers for diagnosing myocardial injury and acute myocardial infarction (ami). |
2019-07-10 |
2023-08-13 |
Not clear |
| Zhi-Li Jia, Juan Cen, Jia-Bo Wang, Feng Zhang, Qing Xia, Xue Wang, Xi-Qiang Chen, Rong-Chun Wang, Chung-der Hsiao, Ke-Chun Liu, Yun Zhan. Mechanism of isoniazid-induced hepatotoxicity in zebrafish larvae: Activation of ROS-mediated ERS, apoptosis and the Nrf2 pathway. Chemosphere. vol 227. 2019-07-10. PMID:31004821. |
the results showed that inh (4, 6 mm) significantly caused liver atrophy and increased levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast) in zebrafish. |
2019-07-10 |
2023-08-13 |
cat |
| Michael Stephen McEntire, Carlos R Sanche. Multimodal Drug Therapy and Physical Rehabilitation in the Successful Treatment of Capture Myopathy in a Lesser Flamingo (Phoeniconaias minor). Journal of avian medicine and surgery. vol 31. issue 3. 2019-07-09. PMID:28891689. |
results of blood tests showed severely elevated creatine phosphokinase (cpk) and aspartate aminotransferase (ast) activities, confirming suspected capture myopathy. |
2019-07-09 |
2023-08-13 |
Not clear |
| Ya-Ling Yang, Hsing-Chun Kuo, Feng-Sheng Wang, Ying-Hsien Huan. MicroRNA-29a Disrupts DNMT3b to Ameliorate Diet-Induced Non-Alcoholic Steatohepatitis in Mice. International journal of molecular sciences. vol 20. issue 6. 2019-07-09. PMID:30917489. |
the results demonstrated that increased mir-29a alleviated the mcd diet-induced body weight loss and steatosis and decreased aspartate aminotransferase (ast) levels in mice. |
2019-07-09 |
2023-08-13 |
mouse |
| Naourez Ktari, Intidhar Bkhairia, Rim Nasri, Rihab Ben Abdallah Kolsi, Rabab Ben Slama-Ben Salem, Ibtissem Ben Amara, Najiba Zeghal, Basma Ben Salah, Riadh Ben Salah, Moncef Nasr. Zebra blenny protein hydrolysates as a source of bioactive peptides with prevention effect against oxidative dysfunctions and DNA damage in heart tissues of rats fed a cholesterol-rich diet. Food research international (Ottawa, Ont.). vol 100. issue Pt 1. 2019-07-08. PMID:28873705. |
hcd promoted oxidative stress with a rise in serum aspartate aminotransferase (ast) and lactate dehydrogenase (ldh) activities and thiobarbituric acid reactive substance (tbars), advanced oxidation protein product (aopp) and hydrogen peroxide (h |
2019-07-08 |
2023-08-13 |
human |
| Shuai Zheng, Shulin Shao, Zhiyu Qiao, Xue Chen, Chunmei Piao, Ying Yu, Feng Gao, Jie Zhang, Jie D. Clinical Parameters and Gut Microbiome Changes Before and After Surgery in Thoracic Aortic Dissection in Patients with Gastrointestinal Complications. Scientific reports. vol 7. issue 1. 2019-07-08. PMID:29123168. |
levels of white blood cells (wbc), neutrophile granulocytes (ne), alanine aminotransferase (alt), and aspartate aminotransferase (ast) were higher in all patients after surgery. |
2019-07-08 |
2023-08-13 |
Not clear |
| Eleni Asprouli, Ioanna Panagiota Kalafati, Aikaterini Sakellari, Sotirios Karavoltsos, John Vlachogiannakos, Konstantinos Revenas, Alexander Kokkinos, Manos Dassenakis, George V Dedoussis, Nick Kalogeropoulo. Evaluation of Plasma Trace Elements in Different Stages of Nonalcoholic Fatty Liver Disease. Biological trace element research. vol 188. issue 2. 2019-07-08. PMID:30014284. |
the disease was diagnosed by abdominal ultrasound; blood samples were analyzed for total, hdl and ldl cholesterol, triglycerides, fasting glucose, fasting insulin, and liver enzymes, namely aspartate aminotransferase (ast), alanine transaminase (alt), and γ-glutamyltransferase (gamma-gt); insulin resistance was determined by the homeostatic model assessment (homa-ir). |
2019-07-08 |
2023-08-13 |
Not clear |
| Mohamed M Abdel-Daim, Ismail A M Eissa, Ahmed Abdeen, Hany M R Abdel-Latif, Mona Ismail, Mahmoud A O Dawood, Ahmed M Hassa. Lycopene and resveratrol ameliorate zinc oxide nanoparticles-induced oxidative stress in Nile tilapia, Oreochromis niloticus. Environmental toxicology and pharmacology. vol 69. 2019-07-08. PMID:30953933. |
results revealed a considerable elevation of aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), cholesterol, urea, and creatinine with a noticeable lowering of total proteins and albumin serum levels in response to znonp intoxication. |
2019-07-08 |
2023-08-13 |
cat |
| Emily R Blatt, Kathryn E Seeley, Mathew C Lovett, Randall E Jung. MANAGEMENT OF A REEVE'S MUNTJAC ( MUNTIACUS REEVESI) WITH SEIZURES USING LEVETIRACETAM. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. vol 48. issue 4. 2019-07-01. PMID:29297840. |
because of continued epileptic seizures and low serum phenobarbital levels, the dose was increased until significant elevations of aspartate aminotransferase (ast) and alkaline phosphatase (alp) were detected. |
2019-07-01 |
2023-08-13 |
Not clear |