| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shay Mailloux, Oleksandr Zavalov, Nataliia Guz, Evgeny Katz, Vera Bocharov. Enzymatic filter for improved separation of output signals in enzyme logic systems towards 'sense and treat' medicine. Biomaterials science. vol 2. issue 2. 2020-06-02. PMID:32481878. |
this sensing system used the enzymes alanine transaminase (alt) and aspartate transaminase (ast) as the inputs. |
2020-06-02 |
2023-08-13 |
human |
| Amir Abbasnezhad, Razieh Choghakhori, Sara Kashkooli, Meysam Alipour, Omid Asbaghi, Rasool Mohammad. Effect of L-carnitine on liver enzymes and biochemical factors in hepatic encephalopathy: A systematic review and meta-analysis. Journal of gastroenterology and hepatology. vol 34. issue 12. 2020-06-01. PMID:31254469. |
we aimed to investigate the effect of l-carnitine on biochemical factors including ammonia, bilirubin, albumin, alanine aminotransferase, aspartate aminotransferase (ast), blood urea nitrogen (bun), and creatinine (cr) in patients with hepatic encephalopathy (he). |
2020-06-01 |
2023-08-13 |
Not clear |
| Jinho Yang, Andrea McDowell, Eun Kyoung Kim, Hochan Seo, Kyujin Yum, Won Hee Lee, Young-Koo Jee, Yoon-Keun Ki. Consumption of a Leuconostoc holzapfelii-enriched synbiotic beverage alters the composition of the microbiota and microbial extracellular vesicles. Experimental & molecular medicine. vol 51. issue 8. 2020-05-29. PMID:31371728. |
blood chemistry assays revealed that synbiotic consumption significantly lowered aspartate aminotransferase (ast) serum levels, particularly in subjects with starting levels above the normal range (>40 ui/l). |
2020-05-29 |
2023-08-13 |
human |
| Shrirang Inamdar, Ankita Joshi, Sajad Malik, Ramanamurthy Boppana, Saroj Ghaskadb. Vitexin alleviates non-alcoholic fatty liver disease by activating AMPK in high fat diet fed mice. Biochemical and biophysical research communications. vol 519. issue 1. 2020-05-27. PMID:31472955. |
serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels were reduced significantly by vitexin which were elevated in hfd group whereas serum lipase activity remained unchanged. |
2020-05-27 |
2023-08-13 |
mouse |
| Qing Xiao, Shujun Zhang, Huina Ren, Ruoyang Du, Jiajun Li, Jinqiu Zhao, Yue Gao, Yali Zhu, Wenxiang Huan. Ginsenoside Rg1 alleviates ANIT-induced intrahepatic cholestasis in rats via activating farnesoid X receptor and regulating transporters and metabolic enzymes. Chemico-biological interactions. vol 324. 2020-05-26. PMID:32198087. |
then the pathological changes in liver tissue were observed, the secretion of bile in the bile duct was measured, and the biochemical markers in serum were quantified, including alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), glutamyl transfer peptidase (gtp) and the content of total bilirubin (tbil), direct bilirubin (dbil), total bile acid (tba). |
2020-05-26 |
2023-08-13 |
rat |
| Rachel Strauss, Alex Cressman, Mark Cheung, Adina Weinerman, Suzanne Waldman, Edward Etchells, Alireza Zahirieh, Piero Tartaro, Jeremy Rezmovitz, Jeannie Callu. Major reductions in unnecessary aspartate aminotransferase and blood urea nitrogen tests with a quality improvement initiative. BMJ quality & safety. vol 28. issue 10. 2020-05-21. PMID:31073091. |
aspartate aminotransferase (ast), commonly ordered with alanine aminotransferase (alt) and blood urea nitrogen (bun), commonly ordered with creatinine (cr), often add little value to patient management at significant cost. |
2020-05-21 |
2023-08-13 |
Not clear |
| Guadalupe Garcia-Tsao, Michael Fuchs, Mitchell Shiffman, Brian B Borg, Nikolaos Pyrsopoulos, Kirti Shetty, Juan F Gallegos-Orozco, K Rajender Reddy, Eyob Feyssa, Jean L Chan, Mason Yamashita, James M Robinson, Alfred P Spada, David T Hagerty, Jaime Bosc. Emricasan (IDN-6556) Lowers Portal Pressure in Patients With Compensated Cirrhosis and Severe Portal Hypertension. Hepatology (Baltimore, Md.). vol 69. issue 2. 2020-05-20. PMID:30063802. |
aspartate aminotransferase (ast) and alanine aminotransferase (alt) decreased significantly in the entire group and in those with severe ph. |
2020-05-20 |
2023-08-13 |
human |
| Kyoung-Nam Kim, Jungmin Joo, Ho Kyung Sung, Chee Hae Kim, Haebin Kim, Yong Jin Kwo. Associations of serum liver enzyme levels and their changes over time with all-cause and cause-specific mortality in the general population: a large-scale national health screening cohort study. BMJ open. vol 9. issue 5. 2020-05-18. PMID:31154308. |
to investigate the associations of the levels of liver enzymes, such as alanine aminotransferase (alt), aspartate aminotransferase (ast) and gamma glutamyltransferase (ggt), at baseline and their changes over time with mortality. |
2020-05-18 |
2023-08-13 |
Not clear |
| Fatma Farrag Ali, Rehab Ahmed Rifaa. Preventive effect of omega-3 fatty acids in a rat model of stress-induced liver injury. Journal of cellular physiology. vol 234. issue 7. 2020-05-11. PMID:30536657. |
serum was obtained to determine corticosterone (cort), alanine aminotransferase (alt), aspartate aminotransferase (ast), and tumor necrosis factor-α (tnf-α) levels. |
2020-05-11 |
2023-08-13 |
rat |
| Chen-Yuan Chiu, Tsai-En Yen, Shing-Hwa Liu, Meng-Tsan Chian. Comparative Effects and Mechanisms of Chitosan and Its Derivatives on Hypercholesterolemia in High-Fat Diet-Fed Rats. International journal of molecular sciences. vol 21. issue 1. 2020-05-11. PMID:31877743. |
unexpectedly, a 5% co-supplemented diet exerted hepatic damage, producing increased levels of aspartate aminotransferase (ast), alanine aminotransferase (alt), and tumor necrosis factor-alpha (tnf-α). |
2020-05-11 |
2023-08-13 |
rat |
| Yue-Meng Wan, Zhi-Qiang Li, Chang Liu, Yue-Feng He, Men-Jie Wang, Xi-Nan Wu, Yuan Zhang, Yu-Hua L. Mesenchymal stem cells reduce alcoholic hepatitis in mice via suppression of hepatic neutrophil and macrophage infiltration, and of oxidative stress. PloS one. vol 15. issue 2. 2020-05-07. PMID:32045450. |
compared to the control mice, the ah mice had significantly increased liver/body weight ratio, serum alanine aminotransferase (alt) and aspartate aminotransferases (ast), hepatic total cholesterol (tc), triglyceride (tg), malondialdehyde (mda), hepatic neutrophil and macrophage infiltration (p<0.001), which were markedly reduced by i.p. |
2020-05-07 |
2023-08-13 |
mouse |
| Murat Akarsu, Mehmet Hurşitoğlu, Zeki Toprak, Şengül Aydin Yoldemir, Özgür Altun, Ilkim Deniz Toprak, Mustafa Özcan, Gülden Yürüyen, Bilal Uğurlukişi, Mahmut Genco Erdem, Kerem Kirna, Pinar Demir, Gazi Çapar, Yücel Arman, Tufan Tüke. Relationships among oncostatin M, insulin resistance, and chronic inflammation: a pilot study. Archives of endocrinology and metabolism. vol 64. issue 1. 2020-05-06. PMID:31576964. |
the fasting blood concentrations of insulin, glucose, blood urea nitrogen (bun), creatinine, aspartate aminotransferase (ast), alanine aminotransferase (alt), low-density lipoprotein cholesterol (ldl-c), high-density lipoprotein cholesterol (hdl-c), triglyceride, total cholesterol, c-reactive protein (crp), and osm were determined. |
2020-05-06 |
2023-08-13 |
human |
| Lihong Chen, Lina Zhang, Zhu Zhu, Wubing He, Lingyun Gao, Wenmin Zhang, Jingfeng Liu, Aimin Huan. Effects of IL-10- and FasL-overexpressing dendritic cells on liver transplantation tolerance in a heterotopic liver transplantation rat model. Immunology and cell biology. vol 97. issue 8. 2020-05-05. PMID:30977930. |
imdcs were intraperitoneally injected into recipient rats as a model of lt to examine the rejection grade [banff rejection activity index (rai)], liver functions [alanine aminotransferase, aspartate aminotransferase (ast) and total bilirubin (tbil)] and post-transplant survival. |
2020-05-05 |
2023-08-13 |
human |
| Yousseu Nana William, Ateufack Gilbert, Abdul Jabbar Shah, Fazli Wahid, Mbiantcha Marius, Muhammad Arfat Yameen, Syed Luqman Shah, Kashif Bashir, Wasim Sajjad, Jules-Roger Kuiate, Kamanyi Albert, Taous Kha. Curative effects of Distemonanthus benthamianus Baillon. Trunk-bark extracts on enteropathogenic Escherichia coli 31-induced diarrhea in rats. Journal of complementary & integrative medicine. vol 16. issue 4. 2020-05-05. PMID:31125314. |
the aqueous extract (100 mg/kg) significantly (p<0.01) increased alanine aminotransferase (alt) serum concentration; while the methanolic extract (100 mg/kg) exhibited similar effect over aspartate aminotransferase (ast). |
2020-05-05 |
2023-08-13 |
rat |
| Grégory Merlen, Valérie-Ann Raymond, Shamir Cassim, Pascal Lapierre, Marc Bilodea. Oxaloacetate Protects Rat Liver From Experimental Warm Ischemia/Reperfusion Injury by Improving Cellular Energy Metabolism. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society. vol 25. issue 4. 2020-05-04. PMID:30663275. |
administration of oaa significantly reduced the extent of liver injury in the lpvl model with lower levels of alanine aminotransferase (alt; p < 0.01), aspartate aminotransferase (ast; p < 0.01), and reduced liver necrosis (p < 0.05). |
2020-05-04 |
2023-08-13 |
rat |
| Zohreh Sadat Sangsefidi, Mahdieh Hosseinzadeh, Ali Mohammad Ranjbar, Mohsen Akhondi-Meybodi, Hossein Fallahzadeh, Hassan Mozaffari-Khosrav. The effect of total anthocyanin-base standardized (Cornus mas L.) fruit extract on liver function, tumor necrosis factor α, malondealdehyde, and adiponectin in patients with non-alcoholic fatty liver: a study protocol for a double-blind randomized clinical trial. Nutrition journal. vol 18. issue 1. 2020-05-04. PMID:31324181. |
thus, the aim of this research will be to evaluate the effect of supplementation with total anthocyanin-base standardized cornelian cherry fruit extract on liver function (serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), cytokeratin-18 fragment m30 (ck-18 m30), as well as steatosis and fibrosis of liver), tumor necrosis factor α (tnf-α), malondealdehyde (mda), and adiponectin in patients with nafld. |
2020-05-04 |
2023-08-13 |
Not clear |
| Chao Han, Yuanyuan Wei, Yuqing Cui, Yumemg Geng, Yongzhan Bao, Wanyu Sh. Florfenicol induces oxidative stress and hepatocyte apoptosis in broilers via Nrf2 pathway. Ecotoxicology and environmental safety. vol 191. 2020-05-04. PMID:31991393. |
the results showed that compared with the control group, except for 0.15 g/l ffc, the other doses of ffc significantly decreased the weight gain, white blood cell (wbc) and platelet (plt) contents in blood, 0.3 g/ml ffc and 1.8 g/l ffc significantly reduced the content of hemoglobin (rgb) (p < 0.05); all doses of ffc significant decreased red blood cell (rbc) increased alanine aminotransferase (alt) and aspartate aminotransferase (ast) contents in serum of chickens (p < 0.05), and significantly decreased the contents of albumin (alb) and total protein (tp) in serum (p < 0.05), but had no significant effect on alkaline phosphatase (alp) contents(p > 0.05). |
2020-05-04 |
2023-08-13 |
cat |
| Ichiro Nakamura, Hiroshi Maegawa, Kazuyuki Tobe, Satoshi Un. Safety and Effectiveness of Ipragliflozin for Type 2 Diabetes in Japan: 12-Month Interim Results of the STELLA-LONG TERM Post-Marketing Surveillance Study. Advances in therapy. vol 36. issue 4. 2020-05-01. PMID:30767112. |
we also evaluated the effect of ipragliflozin on aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels in patients with normal vs. abnormal liver function. |
2020-05-01 |
2023-08-13 |
Not clear |
| Fengwu Li, Zhiying Yang, Christopher Stone, Jamie Y Ding, Lauren Previch, Jiamei Shen, Yu Ji, Xiaokun Geng, Yuchuan Din. Phenothiazines Enhance the Hypothermic Preservation of Liver Grafts: A Pilot in Vitro Study. Cell transplantation. vol 28. issue 3. 2020-04-30. PMID:30666889. |
the extent of liver injury following preservation was determined by alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities, the ratio of ast/alt, morphological changes as assessed by hematoxylin-eosin staining, apoptotic cell death as determined by elisa, and by expression of the apoptotic regulatory proteins bax and bcl-2. |
2020-04-30 |
2023-08-13 |
rat |
| Gadah Albasher, Rafa Almeer, Fatimah O Al-Otibi, Noorah Al-Kubaisi, Ayman M Mahmou. Ameliorative Effect of Biomolecules. vol 9. issue 7. 2020-04-30. PMID:31284640. |
cpf caused liver injury evidenced by elevated serum levels of serum alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp) and bilirubin, along with several histological alterations. |
2020-04-30 |
2023-08-13 |
rat |