| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xue-Ping Yu, Xiao Wen, Jing Li, Yi-Juan Zheng, Jian-Fei Long, Wei-Dong Zhao, Pei-Xue Jiang, Jing-Wen Wu, Bei-Di Zhu, Qi-Rong Jiang, Fei-Fei Yang, Zhong-Liang Shen, Ri-Cheng Mao, Zhi-Jun Su, Ji-Ming Zhan. A promising non-invasive index for predicting liver inflammation in chronic hepatitis B patients with alanine aminotransferase ≤2 upper limit of normal. Experimental and therapeutic medicine. vol 16. issue 6. 2020-09-29. PMID:30542389. |
for the experimental assessment cohort, univariate and multivariate analysis identified aspartate aminotransferase (ast) and albumin (alb) as independent predictors of liver necroinflammation [liver necroinflammation grade (g)≥2] in patients with alt ≤2 uln. |
2020-09-29 |
2023-08-13 |
Not clear |
| Çiğdem Sevim, Selim Çomaklı, Ali Taghizadehghalehjoughi, Mustafa Özkaraca, Robin Mesnage, Leda Kovatsi, Tatyana I Burykina, Alexandra Kalogeraki, Michael N Antoniou, Aristidis Tsatsaki. An imazamox-based herbicide causes apoptotic changes in rat liver and pancreas. Toxicology reports. vol 6. 2020-09-29. PMID:30560060. |
alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities, glucose, calcium as well as creatinine, were determined in blood samples, which were collected after 24, 48 and 72 h exposure. |
2020-09-29 |
2023-08-13 |
rat |
| Yuemin Nan, Xuemin Niu, Rongqi Wang, Suxian Zhao, Na Fu, Jinghua Du, Yang Wang, Baoyu Wang, Yuguo Zhan. microRNA-1273g-3p is a useful non-invasive test for the prediction of liver fibrosis in patients with chronic hepatitis C. Experimental and therapeutic medicine. vol 17. issue 3. 2020-09-29. PMID:30783454. |
liver fibrosis was determined based on meta-analysis of histological data in viral hepatitis classification, and the aspartate aminotransferase (ast)-to-platelet count (plt) ratio index (apri) and fibrosis-4 score (fib-4) were calculated. |
2020-09-29 |
2023-08-13 |
Not clear |
| Nazish Butt, Sehrish Reema, M Ali Khan, Amanullah Abbasi, Sehrish Butt, Mohammad M Khoso, Ali Akbar, Farhan Haleem, Ghulam B Mahesar, Anoshia Fahad, Talha Quresh. Efficacy and Safety of Sofosbuvir and Ribavirin for Treating Chronic Hepatitis C, Genotype 3: Experience of a Tertiary Care Hospital at Karachi, Pakistan. Cureus. vol 11. issue 4. 2020-09-29. PMID:31205844. |
the mean alanine transaminase (alt), aspartate aminotransferase (ast), and gamma-glutamyl transferase (ggt) levels at presentation were 41.89 ± 46.23 iu/l, 68.57 ± 83.62 iu/l, and 54.52 ± 77.57 iu/l, respectively. |
2020-09-29 |
2023-08-13 |
Not clear |
| Dan Thompso. Successful treatment of JFMS open reports. vol 5. issue 1. 2020-09-29. PMID:31210959. |
initial blood testing was non-specific with mild-to-moderate increases in alanine aminotransferase (alt) (194 iu/l; reference interval [ri] 17-62 iu/l), aspartate aminotransferase (ast; 150 iu/l [ri 0-51 iu/l]) and total bilirubin (20 µmol/l; ri 0-11 µmol/l), and neutropenia (1.17 ×10 |
2020-09-29 |
2023-08-13 |
cat |
| Yan Luo, Guoyan Tian, Zhenjie Zhuang, Jin Chen, Ningning You, Lili Zhuo, Bingtian Liang, Yu Song, Shufei Zang, Juan Liu, Jin Yang, Weihong Ge, Junping Sh. Berberine prevents non-alcoholic steatohepatitis-derived hepatocellular carcinoma by inhibiting inflammation and angiogenesis in mice. American journal of translational research. vol 11. issue 5. 2020-09-29. PMID:31217846. |
berberine significantly reduced the levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), glucose (glu), high-density lipoprotein (hdl), low-density lipoprotein (ldl) and total cholesterol (tc). |
2020-09-29 |
2023-08-13 |
mouse |
| Yudong Wei, Hua Zhang, Shuang Zhang, Haiyan L. The influence of diet upon liver function indices of healthy volunteers resident in a Phase I clinical trail. American journal of translational research. vol 11. issue 5. 2020-09-29. PMID:31217888. |
liver biochemical indices such as alkaline phosphatase (alp), alanine aminotransferase (alt), aspartate aminotransferase (ast) were detected on day-1 (baseline), day 1, day 2, day 3, day 5, day 7, day 9, day 12, day 15 and day 22 (follow-up). |
2020-09-29 |
2023-08-13 |
human |
| Muhammad Waqas, Yaping Wang, Aoyun Li, Hammad Qamar, Wangyuan Yao, Xiaole Tong, Jialu Zhang, Mudassar Iqbal, Khalid Mehmood, Jiakui L. Osthole: A Coumarin Derivative Assuage Thiram-Induced Tibial Dyschondroplasia by Regulating Antioxidants (Basel, Switzerland). vol 8. issue 9. 2020-09-29. PMID:31443437. |
thiram feeding resulted in lameness, increased mortality, and decreased production parameters, alkaline phosphatase (alp), superoxide dismutase (sod), total antioxidant capacity (t-aoc), and glutathione peroxidase (gsh-px) levels, along with significantly increased aspartate aminotransferase (ast), alanine aminotransferase (alt), malondialdehyde (mda) levels, and growth plate size. |
2020-09-29 |
2023-08-13 |
Not clear |
| Michi Shibata, Kei Nakajima, Ryoko Higuchi, Taizo Iwane, Michiko Sugiyama, Teiji Nakamur. High Concentration of Serum Aspartate Aminotransferase in Older Underweight People: Results of the Kanagawa Investigation of the Total Check-Up Data from the National Database-2 (KITCHEN-2). Journal of clinical medicine. vol 8. issue 9. 2020-09-29. PMID:31443545. |
aspartate aminotransferase (ast) is pivotal in amino acid metabolism. |
2020-09-29 |
2023-08-13 |
Not clear |
| Roberta Attanasi. Association between perfluoroalkyl acids and liver function: Data on sex differences in adolescents. Data in brief. vol 27. 2020-09-29. PMID:31687437. |
the outcome of interest was represented by changes in biomarkers of liver function, including alanine aminotransferase (alt), aspartate aminotransferase (ast), and gamma-glutamyl transferase (ggt). |
2020-09-29 |
2023-08-13 |
Not clear |
| Xingyao Long, Jiajia Song, Xin Zhao, Yu Zhang, Hongwei Wang, Xinqi Liu, Huayi Su. Silkworm pupa oil attenuates acetaminophen-induced acute liver injury by inhibiting oxidative stress-mediated NF-κB signaling. Food science & nutrition. vol 8. issue 1. 2020-09-29. PMID:31993149. |
our results showed that the liver index and the levels of serum alanine transaminase (alt) and aspartate transaminase (ast) in mice subjected to apap treatment were decreased by spo. |
2020-09-29 |
2023-08-13 |
mouse |
| Hyuckgoo Kim, Sang-Jin Park, Deokhee Le. Hypoxic hepatitis during the perioperative period in patients with severe pulmonary disease and cor pulmonale. Saudi journal of anaesthesia. vol 11. issue 3. 2020-09-28. PMID:28757837. |
after surgery, aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels suddenly increased to 3740 and 817 u/l, respectively. |
2020-09-28 |
2023-08-13 |
Not clear |
| Weizhen Li, Songwen Chen, Genqing Zhou, Hongli Li, Lan Zhong, Shaowen Li. Potential role of cyanidin 3-glucoside (C3G) in diabetic cardiomyopathy in diabetic rats: An in vivo approach. Saudi journal of biological sciences. vol 25. issue 3. 2020-09-28. PMID:29686513. |
the range of myocardial enzymes such as aspartate aminotransferase (ast), creatine kinase (ck) and lactate dehydrogenase (ld) were also estimated, further, the immuno histochemical analysis and western blot investigation were determined for the actual activity of c3g. |
2020-09-28 |
2023-08-13 |
rat |
| Zhi-Ming Ding, Yue Xiao, Xikun Wu, Haixia Zou, Shurong Yang, Yiyun Shen, Juehua Xu, Heather C Workman, Amy L Usborne, Haiqing Hu. Progression and Regression of Hepatic Lesions in a Mouse Model of NASH Induced by Dietary Intervention and Its Implications in Pharmacotherapy. Frontiers in pharmacology. vol 9. 2020-09-28. PMID:29765319. |
in the same period, the mice exhibited elevated alt (alanine aminotransferase) and ast (aspartate aminotransferase) enzyme activities, ck18 (cytokeratin-18), piiinp (n-terminal propeptide of type iii collagen), and timp-1 (tissue inhibitor of metalloproteinase-1). |
2020-09-28 |
2023-08-13 |
mouse |
| Maha I Alkhalf, Fares K Khalif. Blueberry extract attenuates γ-radiation-induced hepatocyte damage by modulating oxidative stress and suppressing NF-κB in male rats. Saudi journal of biological sciences. vol 25. issue 7. 2020-09-28. PMID:30505169. |
in subsequent determinations, γ-irradiated rats had increased levels of cholesterol, triglyceride, high density lipoprotein (hdl) and low density lipoprotein (ldl), and significantly elevated liver enzyme activities, including alanine aminotransferase (alt), aspartate aminotransferase (ast) and alkaline phosphatase (alp), and total bilirubin. |
2020-09-28 |
2023-08-13 |
rat |
| Sabah Kadhim, Narendra P Singh, Elizabeth E Zumbrun, Taixing Cui, Saurabh Chatterjee, Lorne Hofseth, Abduladheem Abood, Prakash Nagarkatti, Mitzi Nagarkatt. Resveratrol-Mediated Attenuation of Frontiers in microbiology. vol 9. 2020-09-28. PMID:30619104. |
we observed that seb caused acute liver injury in mice with increases in enzyme aspartate transaminase (ast) levels, and massive infiltration of immune cells into the liver. |
2020-09-28 |
2023-08-13 |
mouse |
| Suzan B Abdu, Fatima M Al-Bogam. Influence of resveratrol on liver fibrosis induced by dimethylnitrosamine in male rats. Saudi journal of biological sciences. vol 26. issue 1. 2020-09-28. PMID:30622427. |
resveratrol has also inhibited the elevation of serum aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp) and bilirubin levels. |
2020-09-28 |
2023-08-13 |
rat |
| Mohammad AlWahsh, Amnah Othman, Lama Hamadneh, Ahmad Telfah, Jörg Lambert, Suhair Hikmat, Amin Alassi, Fatma El Zahraa Mohamed, Roland Hergenröder, Tariq Al-Qirim, Steven Dooley, Seddik Hamma. Second exposure to acetaminophen overdose is associated with liver fibrosis in mice. EXCLI journal. vol 18. 2020-09-28. PMID:30956639. |
alanine amino transferase (alt) and aspartate amino transferase (ast) levels revealed that the fulminant liver damage was reduced after the second apap administration compared to that observed at the same time point after the first treatment. |
2020-09-28 |
2023-08-13 |
mouse |
| Shaneez Najmy, Ajay Duseja, Arnab Pal, Suchet Sachdev, Rati R Sharma, Neelam Marwah, Yogesh Chawl. Redefining the Normal Values of Serum Aminotransferases in Healthy Indian Males. Journal of clinical and experimental hepatology. vol 9. issue 2. 2020-09-28. PMID:31024201. |
the normal range for aspartate and alanine aminotransferases (ast and alt) levels (<40 iu/l) were set in 1950s. |
2020-09-28 |
2023-08-13 |
Not clear |
| Hongyi Yang, Daihong Guo, Yuanjie Xu, Man Zhu, Chong Yao, Chao Chen, Wangping Ji. Comparison of Different Liver Test Thresholds for Drug-Induced Liver Injury: Updated RUCAM versus Other Methods. Frontiers in pharmacology. vol 10. 2020-09-28. PMID:31379581. |
rucam criteria were defined as the gold standard, and the other two criteria were as follows: 1) alt or aspartate aminotransferase (ast) levels greater than 5 × the uln on two consecutive occasions and/or alp levels greater than 2 × the uln on two consecutive occasions [issued by dili network (dilin)]; 2) alt levels greater than 1 × the uln on two consecutive occasions or alt levels greater than 2 × the uln [issued by the national medical products administration (nmpa) of china]. |
2020-09-28 |
2023-08-13 |
Not clear |