| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Koperska, M Moszak, A Seraszek-Jaros, P Bogdanski, M Szulinsk. Does berberine impact anthropometric, hepatic, and metabolic parameters in patients with metabolic dysfunction-associated fatty liver disease? Randomized, double-blind placebo-controlled trial. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 75. issue 3. 2024-07-23. PMID:39042390. |
in the bbr group, we found significant correlations between changes and amelioration of certain variables: Δ body mass index (bmi) correlated with Δalt (r=0.47; p=0.0089) and d aspartate aminotransferase (ast) (r=0.47; p=0.0081) levels; Δ trunk fat with Δ fatty liver index (fli) (r=0.55; p=0.0337), Δ homeostasis model assessment for insulin resistant index (homa-ir) (r=0.37; p=0.0020), and ast (r=0.42; p=0.0202); d the de ritis ratio correlated with Δ fibrosis-4 index (fib-4) levels (r=0.59; p=0.0011); and Δfli correlated with Δhoma-ir (r=0.37; p=0.0409) and Δ visceral adiposity index (vai) (r=0.54; p=0.0019), while no significant differences were observed in the placebo group. |
2024-07-23 |
2024-07-25 |
Not clear |
| X Yan, K-J Mu, Q Wen, J Bian, D Yang, W-N Gao, W-M Zhan. Analyzing the impact of acupuncture in conjunction with a Quantum lipid-lowering device on hyperlipidemic rats: insights into adenosine monophosphate-activated protein kinase signaling, blood lipids, and gut microbiota. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 75. issue 3. 2024-07-23. PMID:39042391. |
elisa results showed that compared with the model group, acup + quantum group could reduce the levels of total cholesterol (tc), triglycerides (tg), low-density lipoprotein-cholesterol (ldl-c), aspartate transaminase (ast) and aspartate transaminase (alt) in rats with hyperlipidemia (p<0.01), and increase the level of high-density lipoprotein-cholesterol (hdl-c) (p<0.01). |
2024-07-23 |
2024-07-25 |
rat |
| Chen Rong Phang, Azfar Farooqi, Yashvir Sangwa. Unmasking the Unusual: Cryptococcal Pericarditis in a Patient with Liver Failure - a Rare Occurrence. The American journal of case reports. vol 25. 2024-07-22. PMID:39037967. |
initial laboratory workup revealed thrombocytopenia, transaminitis (aspartate transaminase (ast) level of 502 iu/l, alanine transaminase (alt) level of 82 iu/l), hyperbilirubinemia (total bilirubin of 15.7 mg/dl), international nationalized ratio (inr) of 3.6, and lactic acidosis (lactic acid of 11.7 mmol/l). |
2024-07-22 |
2024-07-25 |
human |
| George J Dugbartey, Stephen Atule, Karl K Alornyo, Ismaila Adam. Hepatoprotective potential of alpha-lipoic acid against gliclazide-induced liver injury in high-glucose-exposed human liver cells and experimental type 2 diabetic rats. Biochemical pharmacology. 2024-07-22. PMID:39038553. |
abbreviations: ala, alpha-lipoic acid; alt, alanine aminotransferase; alp, alkaline phosphatase; ampk, adenosine monophosphate-activated protein kinase; ast, aspartate aminotransferase; atp, adenosine triphosphate; dmem, dulbecco's modified eagle medium; edta, ethylenediaminetetraacetic acid; fbg, fasting blood glucose; fbs, fetal bovine serum; glc, gliclazide; glut4, glucose transporter type 4; gsh, glutathione; h&e, hematoxylin/eosin; hba1c, glycosylated haemoglobin a1c; hc, healthy control; hg, hyperglycemic group; homa-β, homeostasis model assessment of β-cell function; il-1β, interleukin-1β; il-6, interleukin-6; inos, inducible nitric oxide synthase; k |
2024-07-22 |
2024-07-25 |
human |
| Heba A Nasr, Nasr-Eldin M Aref, Mahmoud R Abd Ellah, Mohammed Ahmed Hamdy Abdelhakie. Cardiac biomarkers as tools in the prediction and diagnosis of traumatic pericarditis and traumatic reticuloperitonitis in cattle and buffaloes. BMC veterinary research. vol 20. issue 1. 2024-07-20. PMID:39033105. |
the present study was carried out to evaluate the diagnostic significance of cardiac troponin i rapid test cassette and other cardiac biomarkers including serum cardiac troponin i (ctn i), creatine kinase-myocardial band (ck-mb), lactate dehydrogenase (ldh), and aspartate aminotransferase enzyme (ast), in confirmed cases of traumatic pericarditis (tp) and/or traumatic reticuleoperitonitis (trp) in cattle and buffaloes. |
2024-07-20 |
2024-07-24 |
cattle |
| Q Zhang, Y Jiang, Y Qin, J Liu, Y Xie, L Zhang, K Li, X Wang, G Li. Linoleic Acid Alleviates Lipopolysaccharide Induced Acute Liver Injury via Activation of Nrf2. Physiological research. vol 73. issue 3. 2024-07-19. PMID:39027955. |
the results indicated that treatment with la alleviated the histopathological abnormalities in the hepatic and plasma levels of aspartate aminotransferase (ast), alanine aminotransferase (alt), and glutathione-s-transferase (gst) in mice with lps exposure. |
2024-07-19 |
2024-07-21 |
mouse |
| Victor Menezes Tunholi, Ludimila Santos Amaral, Natânia do Carmo Sperandio, Lorena Souza Castro Altoé, Vinícius Menezes Tunholi-Alves, Juberlan Garcia, Ester Maria Mota, Melissa Carvalho Machado do Couto-Chambarelli, Caio Márcio de Oliveira Monteiro, Isabella Vilhena Freire Martin. Metabolic disruptions in Biomphalaria glabrata induced by Heterorhabditis bacteriophora HP88: implications for entomopathogenic nematodes in biological control. Experimental parasitology. 2024-07-17. PMID:39019304. |
in this study, the effect of exposure time (24 or 48 hours) of heterorhabditis bacteriophora hp88 on the activities of alanine aminotransferase (alt) and aspartate aminotransferase (ast), as well as the concentration of total proteins, uric acid, and urea in the hemolymph of biomphalaria glabrata, were investigated. |
2024-07-17 |
2024-07-20 |
Not clear |
| Sevginur Akdas, Nuray Yaziha. From NAFLD to MASLD: Meta-analysis and systematic review of NAFLD patients in Turkiye in terms of metabolic profile and MASLD potential. Hepatology forum. vol 5. issue 3. 2024-07-16. PMID:39006144. |
according to the meta-analysis results, there were significant increases in waist circumferences (mean difference: 10.90, p<0.00001), homa-ir (mean difference: 2.13, p<0.00001), aspartate aminotransferase (ast) (mean difference: 17.82, p<0.00001), systolic blood pressure (sbp) (mean difference: 5.86, p<0.00001), and c-reactive protein (crp) levels (mean difference: 0.95, p<0.00001). |
2024-07-16 |
2024-07-18 |
Not clear |
| Daniel Henrique Souza Tavares, Julián Andrés Castillo Vargas, Vera Lúcia de Araújo Bozorg, Jose Neuman Miranda Neiva, José Helder de Andrade Moura, Ithalo Barros Freitas, Thays Matias da Silva Pinto, Luciano Fernandes Sousa, Fabrícia Rocha Chaves Miott. Impact of replacing protein pellets with soybean grain on nutrient utilization and the rumen and blood parameters of feedlot cattle under tropical conditions. Tropical animal health and production. vol 56. issue 6. 2024-07-11. PMID:38990398. |
protein, albumin, creatinine, triglycerides, aspartate aminotransferase (ast), and alanine aminotransferase (alt)) were not affected (p ≥ 0.139) by the source of protein, the addition of silage, or their interaction. |
2024-07-11 |
2024-07-13 |
cattle |
| S Morrone, S Sechi, C Carta, A Senes, R Cocco, M L Pinna Parpaglia, E Sanna Passino, M G Cappa. Nutritional management of hyperlipaemia in a jenny: a brief report. Veterinary research communications. 2024-07-04. PMID:38963468. |
blood analyses outlined a general undernourishment condition [circulating albumins, alb: 17.6 g/l (21.6-31.6 g/l)] with underlying systemic inflammatory profile and moderate increase in circulating enzymes to explore liver function [aspartate amino-transferase, ast: 657 u/l (279-430 u/l); alanine amino-transferase alt: 60 u/l (5-14 u/l); gamma-glutamyl-transferase, γ-gt: 87 iu/l (14-69 iu/l); total bilirubin close to the upper limit, tb: 0.20 mg/dl(0.07-0.21 mg/dl)]and hyperlipaemia [tg: 8.70 mmol/l (0.60-2.87 mmol/l)], following fat depots mobilisation, with total cholesterol closed to the lower limit of the physiological range. |
2024-07-04 |
2024-07-10 |
Not clear |
| Jasmine Shakir, Megan Pedicini, Brianna C Bullock, Penn W Hoen, Lindsey K Macias, Jackson Freiman, Mikhail V Pletnikov, Kellie Lk Tamashiro, Zachary A Cordne. Effects of psilocybin on body weight, body composition, and metabolites in male and female mice. Physiology & behavior. 2024-07-04. PMID:38964565. |
a metabolic panel revealed increased creatine kinase (ck), aspartate aminotransferase (ast), and chloride among male and female psilocybin treated mice. |
2024-07-04 |
2024-07-11 |
mouse |
| J Gu, Y Chen, J Wang, Y Gao, Z Gai, Y Zhao, F X. Lacticaseibacillus rhamnosus LRa05 alleviated liver injury in mice with alcoholic fatty liver disease by improving intestinal permeability and balancing gut microbiota. Beneficial microbes. 2024-07-03. PMID:38960385. |
alcohol consumption induced liver damage in mice with significantly increased levels of triglycerides (tg), aspartate aminotransferase (ast), alanine transaminase (alt), and inflammatory cytokines. |
2024-07-03 |
2024-07-10 |
mouse |
| Yi Xu, ShuangJie Li, WenXian OuYang, Zhenzhen Yao, Xin Lai, Yingping Gu, Meng Yang, Ling Ye, Sisi Li, Songxu Pen. Clinical and virological characteristics of coexistent hepatitis B surface antigen and antibody in treatment-naive children with chronic hepatitis B virus infection. Frontiers in public health. vol 12. 2024-07-02. PMID:38952725. |
patients with anti-hbs were younger and demonstrated significantly higher ratio of albumin to globulin (a/g), elevated serum levels of alanine transaminase (alt), lower ratio of aspartate transaminase (ast)/alt (ast/alt) and reduced serum levels of globulin, hbsag and hbv dna, additionally, these patients were more likely to show coexistent hbeag and anti-hbe when compared to patients without anti-hbs. |
2024-07-02 |
2024-07-04 |
human |
| Amal M Aboelmaaty, Rasha S Mohamed, Hassan A Hussein, Ragab H Mohame. Fetal gender prediction by monitoring circulating steroid hormones and some biochemical parameters in maternal dromedary camels. Tropical animal health and production. vol 56. issue 6. 2024-07-01. PMID:38951353. |
blood samples were collected for measurements of progesterone, estradiol, testosterone, and cortisol as well as total proteins, albumin, glucose, creatinine, blood urea nitrogen, phosphorus, calcium, creatine kinase, alanine aminotransferase (alt), aspartate transaminase (ast), alkaline phosphatase (alp), gamma glutamyl transpeptidase (ggt), calcium, phosphorus, and magnesium. |
2024-07-01 |
2024-07-04 |
Not clear |
| Xiaoying Chen, Yifan Wang, Jie Wan, Xiaoyun Dou, Chuzhao Zhang, Meng Sun, Fang Y. Quercetin alleviates liver fibrosis via regulating glycolysis of liver sinusoidal endothelial cells and neutrophil infiltration. Biomolecules & biomedicine. 2024-06-29. PMID:38943679. |
this was supported by evidence of improved pathological features and reduced levels of serum markers such as alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), γ-glutamyl transferase (ggt), total bile acid (tba), total bilirubin (tbil), direct bilirubin (dbil), hyaluronic acid (ha), laminin (ln), and procollagen type iii. |
2024-06-29 |
2024-07-02 |
Not clear |
| Amanda Hastenreiter do Espírito Santo, José Fernando López-Olmeda, Gonzalo de Alba, Leandro Santos Costas, Helder de Oliveira Guilherme, Francisco Javier Sánchez-Vázquez, Ronald Kennedy Luz, Paula Adriane Perez Ribeir. Ontogeny of daily rhythms in the expression of metabolic factors in Nile tilapia (Oreochromis niloticus) kept at two different temperature regimes: Thermocycle and constant temperature. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2024-06-29. PMID:38944269. |
the expression levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), malic enzyme, glucose-6-phosphate dehydrogenase (g6pd), phosphofructokinase (pfk) and pyruvate kinase (pk) were analyzed by qpcr. |
2024-06-29 |
2024-07-02 |
Not clear |
| Songul Cetik Yildiz, Cemil Demir, Mustafa Cengiz, Halit Irmak, Betul Peker Cengiz, Adnan Ayhanc. In Vitro Antitumor and Antioxidant Capacity as well as Ameliorative Effects of Fermented Kefir on Cyclophosphamide-Induced Toxicity on Cardiac and Hepatic Tissues in Rats. Biomedicines. vol 12. issue 6. 2024-06-27. PMID:38927407. |
it was observed that alanine transaminase (alt), aspartate transaminase (ast), alkaline phosphatase (alp), lactate dehydrogenase (ldh), creatinine kinase-mb (ck-mb), ischemia modified albumin (ima) and troponin i values, which indicate oxidative stress, increased in the cpx-administered group, and this level approached that of the control in the cpx + kefir groups. |
2024-06-27 |
2024-06-29 |
rat |
| b' Nunzio Antonio Cacciola, Paola De Cicco, Maja Milanovi\\xc4\\x87, Ivan Milovanovi\\xc4\\x87, Aleksandra Mi\\xc5\\xa1an, Danijela Koji\\xc4\\x87, Jelica Simeunovi\\xc4\\x87, Dajana Blagojevi\\xc4\\x87, Tamara Popovi\\xc4\\x87, Aleksandra Arsi\\xc4\\x87, Vladimir Pilija, Anamarija Mandi\\xc4\\x87, Francesca Borrelli, Nata\\xc5\\xa1a Mili\\xc4\\x8. Role of Arthrospira Platensis in Preventing and Treating High-Fat Diet-Induced Hypercholesterolemia in Adult Rats. Nutrients. vol 16. issue 12. 2024-06-27. PMID:38931182.' |
total cholesterol (tc), high-density lipoprotein cholesterol (hdl-c), low-density lipoprotein cholesterol (ldl-c), alanine transaminase (alt) and aspartate transaminase (ast) levels were measured in the blood samples. |
2024-06-27 |
2024-06-29 |
rat |
| Pallavi Gurung, Junmo Lim, Yong-Wan Ki. Preventing High Fat Diet-Induced Obesity and Related Hepatic Steatosis by Chlorin e6-Mediated Photodynamic Therapy. Pharmaceuticals (Basel, Switzerland). vol 17. issue 6. 2024-06-27. PMID:38931396. |
at the end of the study period, dogs that were treated for 35 days with ce6 and exposed to led irradiation (660 nm) either for 10 min (ce6 + 10 min of light) or for 15 min (ce6 + 15 min of light) had decreased body weight, including visceral and subcutaneous fats, lower aspartate transaminase (ast)/alanine transaminase (alt) ratios, and a reduction in the area of individual adipocytes with a concomitant increase in the number of adipocytes. |
2024-06-27 |
2024-06-29 |
mouse |
| Qianru Xiang, Zijun Xia, Hongji Liu, Zichong Ye, Linye Sun, Dongliang Feng, Wenzhen Lia. Isolation and characterization of a hepatoprotective polysaccharide from Lonicera caerulea L. var. edulis Turcz. ex Herd. fruit against APAP-induced acute liver injury mice. International journal of biological macromolecules. 2024-06-27. PMID:38936574. |
in addition, after thp treatment, serum alanine aminotransferase (alt), aspartate aminotransferase (ast) and γ-glutamyl transpeptidase (γgt) in aili mice were successfully down-regulated. |
2024-06-27 |
2024-06-30 |
mouse |