| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B C Joshi, N C Jai. Experimental immunologic thrombocytopenia in dogs: a study of thrombocytopenia and megakaryocytopoiesis. Research in veterinary science. vol 22. issue 1. 1977-04-25. PMID:841193. |
simultaneously, the number of immature megakaryocytes and acetylcholine esterase (ache)-positive small cells (presumably megakaryocyte precursors) increased considerably. |
1977-04-25 |
2023-08-11 |
rabbit |
| B Zadrozna, W Buczk. Influence of fibrinogen degradation products (FDP) on the central action of acetylcholine. Polish journal of pharmacology and pharmacy. vol 28. issue 6. 1977-03-21. PMID:1012988. |
the peptides did not affect the brain acetylcholine level and did not influence the inhibitory effect of physostygmine on ache activity. |
1977-03-21 |
2023-08-11 |
Not clear |
| L L Butcher, L Bilezikjia. Acetylcholinesterase-containing neurons in the neostriatum and substantia nigra revealed after punctate intracerebral injection of di-isopropylfluorophosphate. European journal of pharmacology. vol 34. issue 1. 1977-02-24. PMID:1234757. |
although the significance of dopaminergic--cholinergic interactions in the neostriatum could not be elucidated on the basis of these histochemical data, the thesis was advanced that dopamine neurons in the pars compacta of the substantia nigra also contained ache, possibly to inactivate acetylcholine released from cholinergic fibers afferent to this neural structure. |
1977-02-24 |
2023-08-11 |
rat |
| A Ebel, R Jaffard, C Destrade, G Ayad, P Mandel, B Card. [Changes in cholinergic mechanisms and in learning in three strains of inbred mice after electric stimulation of the dorsal hippocampus]. Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles. vol 283. issue 5. 1977-01-29. PMID:825302. |
the second experiment was aimed at studying the stimulation effect on hippocampal cholinergic mechanisms by testing the two main enzymes involved in acetylcholine synthesis and degradation (choline acetyltransferase = chac and acetylcholinesterase = ache). |
1977-01-29 |
2023-08-11 |
mouse |
| P D Hrdina, D A Peters, R L Singha. Effects of chronic exposure to cadmium, lead and mercury of brain biogenic amines in the rat. Research communications in chemical pathology and pharmacology. vol 15. issue 3. 1977-01-29. PMID:996361. |
effects of chronic (45 days) treatment with different doses of cadmium chloride (0.25 and 1.0 mg/kg/day), methylmercury chloride (0.4 and 4.0 mg/kg/day) and lead acetate (0.2 and 1.0 mg/kg/day) and of 28-day withdrawal of treatment on the levels of acetylcholine (ach) and activity of acetylcholinesterase (ache) in cerebral cortex, and concentration of norepinephrine (ne) and 5-hydroxytryptamine (5-ht) in brain-stem were examined in rats. |
1977-01-29 |
2023-08-11 |
rat |
| L E Westrum, S H Broderso. Acetylcholinesterase activity of synaptic structures in the spinal trigeminal nucleus. Journal of neurocytology. vol 5. issue 8. 1976-12-30. PMID:978231. |
the presence of reaction product at these specific sites suggests that these are areas of high ache activity and that acetylcholine may be important in neurotransmission in these regions. |
1976-12-30 |
2023-08-11 |
Not clear |
| P Skaaring, F Bierrin. On the intrinsic innervation of normal rat liver. Histochemical and scanning electron microscopical studies. Cell and tissue research. vol 171. issue 2. 1976-12-23. PMID:975210. |
as no overlapping of distribution patterns of ache-positive nerve fibers and fluorescent nerve fibers occurs, the ache activity of the nerves of the liver lobules probably reflects the associated presence of acetylcholine in the nerve fibers. |
1976-12-23 |
2023-08-11 |
rat |
| E O Akinrimisi, A I Akinwand. Effect of aqueous extract of Eugenia caryophyllus on brain acetylcholine esterase in rats. West African journal of pharmacology and drug research. vol 2. issue 2. 1976-12-01. PMID:9734. |
the effect of aqueous extract of eugenia caryophyllus on brain acetylcholine esterase (ache) activity in rats was studied. |
1976-12-01 |
2023-08-11 |
rat |
| E O Akinrimisi, A I Akinwand. Effect of aqueous extract of Eugenia caryophyllus on brain acetylcholine esterase in rats. West African journal of pharmacology and drug research. vol 2. issue 2. 1976-12-01. PMID:9734. |
results indicate that the aqueous extract reduced the hydrolysis of acetylcholine (ach) by ache. |
1976-12-01 |
2023-08-11 |
rat |
| S Karcsu, L Tóth, B Csilli. Electron cytochemistry of acetylcholinesterase in the neuromuscular junction during ontogenesis. Zeitschrift fur mikroskopisch-anatomische Forschung. vol 89. issue 3. 1976-09-01. PMID:1229242. |
distribution of ache synthesizing loci parallels with that of acetylcholine sensitive areas. |
1976-09-01 |
2023-08-11 |
rat |
| J Lelorier, F E Shidema. Acetylcholinesterase and responses to acetylcholine in the embryonic chicken heart. The Journal of pharmacy and pharmacology. vol 28. issue 3. 1976-08-23. PMID:6692. |
three and 4 day old embryonic chicken hearts were examined for their responsiveness to acetylcholine and presence of acetylcholinesterase (ache) to determine the role of the enzyme in the cardiac effects of the transmitter. |
1976-08-23 |
2023-08-11 |
chicken |
| J Lelorier, F E Shidema. Acetylcholinesterase and responses to acetylcholine in the embryonic chicken heart. The Journal of pharmacy and pharmacology. vol 28. issue 3. 1976-08-23. PMID:6692. |
in 3 day old hearts the responses to acetylcholine were not affected by the ache inhibitor physostigmine but in 4 day old hearts they were considerably potentiated. |
1976-08-23 |
2023-08-11 |
chicken |
| A Dahlstöm, P O Heiwall, P A Larsso. Comparison between the effect of colchicine and lumicolchicine on axonal transport in rat motor neurons. Journal of neural transmission. vol 37. issue 4. 1976-03-11. PMID:54407. |
the mitotic inhibitor colchicine (col) and its isomer lumi-colchicine (lumi-col) were tested on the axonal transport of acetylcholine (ach), cholineacetyltransferase (cat) and ach-esterase (ache) in rat motor nerves in vivo. |
1976-03-11 |
2023-08-11 |
rat |
| P D Hrdina, P K Ghosh, R B Rastogi, R L Singha. Ontogenic pattern of dopamine, acetylcholine, and acetylcholinesterase in the brains of normal and hypothyroid rats. Canadian journal of physiology and pharmacology. vol 53. issue 5. 1976-03-01. PMID:1201478. |
the influence of neonatal thyroidectomy (tx) on developmental changes in dopamine (da), acetylcholine (ach), and acetylcholinesterase (ache) was studied in the whole brain of rats. |
1976-03-01 |
2023-08-11 |
rat |
| D Ross, A I Cohen, D B McDouga. Choline acetyltransferase and acetylcholine esterase activities in normal and biologically fractionated mouse retinas. Investigative ophthalmology. vol 14. issue 10. 1976-01-10. PMID:1184309. |
radiometric biochemical assays were carried out for choline acetyltransferase (chac) and acetylcholine esterase (ache) in retinas isolated from 90-day-old pigmented mice. |
1976-01-10 |
2023-08-11 |
mouse |
| P G Guyenet, J C Beaujouan, J Glowinsk. Ontogenesis of neostriatal cholinergic neurones in the rat and development of their sensitivity to neuroleptic drugs. Naunyn-Schmiedeberg's archives of pharmacology. vol 288. issue 2-3. 1975-12-04. PMID:1161052. |
simultaneous determinations of the striatal contents in acetylcholine (ach), choline acetyl-transferase (chac) and acetyl-cholinesterase (ache) were made in neonate rats from day 4 to day 16 after birth. |
1975-12-04 |
2023-08-11 |
rat |
| S U Kim, T H Oh, D D Johnso. Increased activity of choline acetyltransferase and acetylcholinesterase in developing cultures of chick spinal cord: a correlation with morphological development. Neurobiology. vol 5. issue 2. 1975-08-26. PMID:1134618. |
two important enzymes associated with acetylcholine transmitter metabolism, choline acetyltransferase (chac) and acetylcholinesterase (ache), were assayed in cultures at selected time intervals. |
1975-08-26 |
2023-08-11 |
chicken |
| R L Metcal. Structure-activity relationships for insecticidal carbamates. Bulletin of the World Health Organization. vol 44. issue 1-3. 1971-12-04. PMID:5315358. |
carbamates behave as synthetic neurohormones that produce their toxic action by interrupting the normal action of ache so that acetylcholine accumulates at synaptic junctions. |
1971-12-04 |
2023-08-11 |
Not clear |