| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F M Mottaghy, B J Krause, L J Kemna, R Töpper, L Tellmann, M Beu, A Pascual-Leone, H W Müller-Gärtne. Modulation of the neuronal circuitry subserving working memory in healthy human subjects by repetitive transcranial magnetic stimulation. Neuroscience letters. vol 280. issue 3. 2000-04-07. PMID:10675787. |
rtms to the right or left dorsolateral prefrontal cortex (dlpfc), but not to the midline frontal cortex, significantly worsened performance in the wm task while inducing significant reductions in rcbf at the stimulation site and in distant brain regions. |
2000-04-07 |
2023-08-12 |
human |
| S A Castner, G V Williams, P S Goldman-Raki. Reversal of antipsychotic-induced working memory deficits by short-term dopamine D1 receptor stimulation. Science (New York, N.Y.). vol 287. issue 5460. 2000-04-04. PMID:10720329. |
chronic blockade of dopamine d2 receptors, a common mechanism of action for antipsychotic drugs, down-regulates d1 receptors in the prefrontal cortex and, as shown here, produces severe impairments in working memory. |
2000-04-04 |
2023-08-12 |
monkey |
| M L Furey, P Pietrini, G E Alexander, M B Schapiro, B Horwit. Cholinergic enhancement improves performance on working memory by modulating the functional activity in distinct brain regions: a positron emission tomography regional cerebral blood flow study in healthy humans. Brain research bulletin. vol 51. issue 3. 2000-03-30. PMID:10718513. |
previously, we have shown that physostigmine, an acetylcholinesterase inhibitor, improved performance on a working memory for faces task, as reflected by reduced reaction time (rt), and reduced task-specific regional cerebral blood flow (rcbf) in right prefrontal cortex and, further, that these reductions in rt and right frontal rcbf were significantly correlated. |
2000-03-30 |
2023-08-12 |
human |
| K Mizoguchi, M Yuzurihara, A Ishige, H Sasaki, D H Chui, T Tabir. Chronic stress induces impairment of spatial working memory because of prefrontal dopaminergic dysfunction. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 4. 2000-02-25. PMID:10662846. |
we therefore examined whether chronically stressed (4 weeks) and recovered (10 d) rats show a working memory impairment caused by reduced dopamine (da) transmission in the pfc, as suspected in the neuropsychiatric disorders. |
2000-02-25 |
2023-08-12 |
rat |
| K Mizoguchi, M Yuzurihara, A Ishige, H Sasaki, D H Chui, T Tabir. Chronic stress induces impairment of spatial working memory because of prefrontal dopaminergic dysfunction. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 4. 2000-02-25. PMID:10662846. |
these results indicate that chronic stress induces working memory impairment through a d1 receptor-mediated hypodopaminergic mechanism in the pfc. |
2000-02-25 |
2023-08-12 |
rat |
| M D'Esposito, B R Postl. The dependence of span and delayed-response performance on prefrontal cortex. Neuropsychologia. vol 37. issue 11. 2000-02-17. PMID:10530730. |
to address this issue, we performed an analysis of reports of performance on tests of working memory of patients with lesions of the dorsolateral prefrontal cortex, focusing on published reports in the literature of simple span and delayed-response tasks. |
2000-02-17 |
2023-08-12 |
Not clear |
| M D'Esposito, B R Postl. The dependence of span and delayed-response performance on prefrontal cortex. Neuropsychologia. vol 37. issue 11. 2000-02-17. PMID:10530730. |
based on the results of our review of the literature, we present testable hypotheses about the working memory functions of the pfc. |
2000-02-17 |
2023-08-12 |
Not clear |
| S G Rao, G V Williams, P S Goldman-Raki. Destruction and creation of spatial tuning by disinhibition: GABA(A) blockade of prefrontal cortical neurons engaged by working memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 1. 2000-01-27. PMID:10627624. |
local circuit neurons in the dorsolateral prefrontal cortex (dpfc) of monkeys have been implicated in the cellular basis of working memory. |
2000-01-27 |
2023-08-12 |
monkey |
| S G Rao, G V Williams, P S Goldman-Raki. Destruction and creation of spatial tuning by disinhibition: GABA(A) blockade of prefrontal cortical neurons engaged by working memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 1. 2000-01-27. PMID:10627624. |
these findings provide the first direct evidence of directional inhibitory modulation of pyramidal cell and interneuron firing in both the mnemonic and sensorimotor phases of the working memory process, and they implicate a further role for gabaergic interneurons in the construction of spatial tuning in prefrontal cortex. |
2000-01-27 |
2023-08-12 |
monkey |
| V Prabhakaran, K Narayanan, Z Zhao, J D Gabriel. Integration of diverse information in working memory within the frontal lobe. Nature neuroscience. vol 3. issue 1. 2000-01-24. PMID:10607400. |
the role of prefrontal cortex in integrating multiple forms of information in working memory may underlie its unique contribution to high-level cognition that demands flexible mental representations. |
2000-01-24 |
2023-08-12 |
human |
| A Bertolino, G Esposito, J H Callicott, V S Mattay, J D Van Horn, J A Frank, K F Berman, D R Weinberge. Specific relationship between prefrontal neuronal N-acetylaspartate and activation of the working memory cortical network in schizophrenia. The American journal of psychiatry. vol 157. issue 1. 2000-01-18. PMID:10618009. |
abnormal activation of the dorsolateral prefrontal cortex and a related cortical network during working memory tasks has been demonstrated in patients with schizophrenia, but the responsible mechanism has not been identified. |
2000-01-18 |
2023-08-12 |
Not clear |
| A Bertolino, G Esposito, J H Callicott, V S Mattay, J D Van Horn, J A Frank, K F Berman, D R Weinberge. Specific relationship between prefrontal neuronal N-acetylaspartate and activation of the working memory cortical network in schizophrenia. The American journal of psychiatry. vol 157. issue 1. 2000-01-18. PMID:10618009. |
the present study was performed to determine whether neuronal pathology of the dorsolateral prefrontal cortex is linked to the activation of the working memory cortical network in patients with schizophrenia. |
2000-01-18 |
2023-08-12 |
Not clear |
| K S LaBar, D R Gitelman, T B Parrish, M Mesula. Neuroanatomic overlap of working memory and spatial attention networks: a functional MRI comparison within subjects. NeuroImage. vol 10. issue 6. 2000-01-13. PMID:10600415. |
double-subtraction analyses yielded additional activations attributable to verbal working memory in premotor cortex, left inferior prefrontal cortex, right inferior parietal lobule, precuneus, and right cerebellum. |
2000-01-13 |
2023-08-12 |
human |
| D B Carr, P O'Donnell, J P Card, S R Sesac. Dopamine terminals in the rat prefrontal cortex synapse on pyramidal cells that project to the nucleus accumbens. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 24. 2000-01-06. PMID:10594085. |
afferents to the prefrontal cortex (pfc) from dopamine neurons in the ventral tegmental area have been implicated in working memory processes and in the pathogenesis of schizophrenia. |
2000-01-06 |
2023-08-12 |
rat |
| S B Floresco, D N Braaksma, A G Phillip. Thalamic-cortical-striatal circuitry subserves working memory during delayed responding on a radial arm maze. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 24. 2000-01-06. PMID:10594086. |
the medial dorsal nuclei of the thalamus (mdnt), the prefrontal cortex, and the ventral striatum form an interconnected neural circuit that may subserve certain types of working memory. |
2000-01-06 |
2023-08-12 |
rat |
| D S Manoach, D Z Press, V Thangaraj, M M Searl, D C Goff, E Halpern, C B Saper, S Warac. Schizophrenic subjects activate dorsolateral prefrontal cortex during a working memory task, as measured by fMRI. Biological psychiatry. vol 45. issue 9. 2000-01-05. PMID:10331104. |
schizophrenic subjects activate dorsolateral prefrontal cortex during a working memory task, as measured by fmri. |
2000-01-05 |
2023-08-12 |
human |
| D S Manoach, D Z Press, V Thangaraj, M M Searl, D C Goff, E Halpern, C B Saper, S Warac. Schizophrenic subjects activate dorsolateral prefrontal cortex during a working memory task, as measured by fMRI. Biological psychiatry. vol 45. issue 9. 2000-01-05. PMID:10331104. |
neuroimaging studies of schizophrenic subjects performing working memory (wm) tasks have demonstrated a relative hypoactivity of prefrontal cortex compared with normal subjects. |
2000-01-05 |
2023-08-12 |
human |
| B Grassi, G Garghentini, A Campana, E Grassi, S Bertelli, P Cinque, M Epifani, A Lazzarin, S Scaron. Spatial working memory in asymptomatic HIV-infected subjects. The Journal of neuropsychiatry and clinical neurosciences. vol 11. issue 3. 1999-12-29. PMID:10440016. |
many clinical and research findings converge to indicate that frontal lobe, basal ganglia, and related neuronal connections are primarily involved in human immunodeficiency virus (hiv) infection; frontal lobe, mainly the prefrontal cortex, has a specialized role in working memory processes. |
1999-12-29 |
2023-08-12 |
human |
| J Newman, A A Grac. Binding across time: the selective gating of frontal and hippocampal systems modulating working memory and attentional states. Consciousness and cognition. vol 8. issue 2. 1999-12-29. PMID:10448002. |
the prefrontal cortex, on the other hand, is widely thought to mediate working memory processes, per se. |
1999-12-29 |
2023-08-12 |
Not clear |
| P D Nixon, R E Passingha. The cerebellum and cognition: cerebellar lesions do not impair spatial working memory or visual associative learning in monkeys. The European journal of neuroscience. vol 11. issue 11. 1999-12-28. PMID:10583495. |
the results show that, unlike the dorsal prefrontal cortex, the cerebellum is not essential for working memory or the executive processes that are necessary for correct performance, though it may contribute to the preparation of responses. |
1999-12-28 |
2023-08-12 |
monkey |