Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Y F Lu, K Tomizawa, A Moriwaki, Y Hayashi, M Tokuda, T Itano, O Hatase, H Matsu. Calcineurin inhibitors, FK506 and cyclosporin A, suppress the NMDA receptor-mediated potentials and LTP, but not depotentiation in the rat hippocampus. Brain research. vol 729. issue 1. 1997-01-29. PMID:8874888. |
the effects of fk506, a ca2+/calmodulin-dependent phosphatase 2b (calcineurin) inhibitor, on the nmda receptor-mediated potentials and synaptic plasticity were investigated in the ca1 region of the rat hippocampus. |
1997-01-29 |
2023-08-12 |
rat |
D M Diamond, M Fleshner, N Ingersoll, G M Ros. Psychological stress impairs spatial working memory: relevance to electrophysiological studies of hippocampal function. Behavioral neuroscience. vol 110. issue 4. 1997-01-17. PMID:8864259. |
stress appears to induce a transient disruption of hippocampal function, which is revealed behaviorally as retrograde amnesia and physiologically as a blockade of synaptic plasticity. |
1997-01-17 |
2023-08-12 |
rat |
M F Bea. A synaptic basis for memory storage in the cerebral cortex. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 24. 1997-01-16. PMID:8942956. |
we have used a theoretical "learning rule," devised to account for experience-dependent shifts in neuronal selectivity, to guide experiments on the elementary mechanisms of synaptic plasticity in hippocampus and neocortex. |
1997-01-16 |
2023-08-12 |
Not clear |
M F Bea. A synaptic basis for memory storage in the cerebral cortex. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 24. 1997-01-16. PMID:8942956. |
these experiments reveal that many synapses in hippocampus and neocortex are bidirectionally modifiable, that the modifications persist long enough to contribute to long-term memory storage, and that key variables governing the sign of synaptic plasticity are the amount of nmda receptor activation and the recent history of cortical activity. |
1997-01-16 |
2023-08-12 |
Not clear |
G B Murzina, I G Sil'ki. [The mathematical modelling of Ca2(+)-dependent postsynaptic processes in the hippocampus (the induction of long-term potentiation and long-term depression)]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 46. issue 4. 1997-01-08. PMID:8984806. |
some results of experimental study of the hippocampal and neocortical synaptic plasticity are explained and systematized. |
1997-01-08 |
2023-08-12 |
Not clear |
J C Siciliano, M Toutant, P Derkinderen, T Sasaki, J A Giraul. Differential regulation of proline-rich tyrosine kinase 2/cell adhesion kinase beta (PYK2/CAKbeta) and pp125(FAK) by glutamate and depolarization in rat hippocampus. The Journal of biological chemistry. vol 271. issue 46. 1997-01-07. PMID:8910543. |
thus, in hippocampal slices, tyrosine phosphorylation of pp125(fak) and pyk2/cakbeta are regulated differentially by pathways involving ca2+ and protein kinase c. pp125(fak) and pyk2/cakbeta may provide specific links between neuronal activity, increases in cytosolic ca2+ and protein tyrosine phosphorylation, which may be important for neuronal survival, and synaptic plasticity. |
1997-01-07 |
2023-08-12 |
rat |
I Krushkov, Ts Markova, A Tsanko. [The participation of nitric oxide in the functions of the central nervous system and the cardiovascular system]. Molekuliarna meditsina = Molecular medicine. vol 1. issue 2. 1997-01-07. PMID:8983811. |
no is involved in the processes of synaptic plasticity in the hippocampus. |
1997-01-07 |
2023-08-12 |
Not clear |
Y Ikegaya, H Saito, K Ab. The basomedial and basolateral amygdaloid nuclei contribute to the induction of long-term potentiation in the dentate gyrus in vivo. The European journal of neuroscience. vol 8. issue 9. 1997-01-02. PMID:8921274. |
to test the possibility that the amygdala modulates hippocampal synaptic plasticity, we investigated the effects of surgical lesions of the amygdaloid nuclei on the induction of long-term potentiation (ltp) in the dentate gyrus of anaesthetized rats. |
1997-01-02 |
2023-08-12 |
rat |
T A Ryan, N E Ziv, S J Smit. Potentiation of evoked vesicle turnover at individually resolved synaptic boutons. Neuron. vol 17. issue 1. 1996-12-23. PMID:8755484. |
we have studied synaptic plasticity in hippocampal cell cultures using a new imaging approach that allows unambiguous discrimination of presynaptic function at the level of single synaptic boutons. |
1996-12-23 |
2023-08-12 |
Not clear |
A Kirkwood, M F Bea. Elementary forms of synaptic plasticity in the visual cortex. Biological research. vol 28. issue 1. 1996-12-05. PMID:8728822. |
however, in contrast to the hippocampus where there has been an increasingly sophisticated analysis of synaptic plasticity, relatively little is known about the mechanisms of synaptic modification in neocortex. |
1996-12-05 |
2023-08-12 |
Not clear |
A K Sesay, M L Errington, L Levita, T V Blis. Spatial learning and hippocampal long-term potentiation are not impaired in mdx mice. Neuroscience letters. vol 211. issue 3. 1996-12-04. PMID:8817577. |
these experiments demonstrate that neither spatial learning nor hippocampal synaptic plasticity are significantly affected by the lack of full-length dystrophin. |
1996-12-04 |
2023-08-12 |
mouse |
P J Meberg, W R Kinney, E G Valcourt, A Routtenber. Gene expression of the transcription factor NF-kappa B in hippocampus: regulation by synaptic activity. Brain research. Molecular brain research. vol 38. issue 2. 1996-12-03. PMID:8793106. |
since nf-kappa b subunit gene expression in the hippocampus is increased by augmented synaptic activity, nf-kappa b activation may contribute to alterations in target gene expression that accompany activity-dependent synaptic plasticity, but only in a combinatorial fashion with other transcription factors. |
1996-12-03 |
2023-08-12 |
Not clear |
T Bonhoeffe. Neurotrophins and activity-dependent development of the neocortex. Current opinion in neurobiology. vol 6. issue 1. 1996-12-03. PMID:8794047. |
in addition, recent data show that a different phenomenon of synaptic plasticity, hippocampal long-term potentiation, also critically depends on neurotrophins. |
1996-12-03 |
2023-08-12 |
Not clear |
D Debann. Associative synaptic plasticity in hippocampus and visual cortex: cellular mechanisms and functional implications. Reviews in the neurosciences. vol 7. issue 1. 1996-11-25. PMID:8736677. |
associative synaptic plasticity in hippocampus and visual cortex: cellular mechanisms and functional implications. |
1996-11-25 |
2023-08-12 |
Not clear |
D Debanne, D E Shulz, Y Frégna. Temporal constraints in associative synaptic plasticity in hippocampus and neocortex. Canadian journal of physiology and pharmacology. vol 73. issue 9. 1996-10-24. PMID:8748980. |
temporal constraints in associative synaptic plasticity in hippocampus and neocortex. |
1996-10-24 |
2023-08-12 |
Not clear |
G Buzsáki, M Penttonen, Z Nádasdy, A Bragi. Pattern and inhibition-dependent invasion of pyramidal cell dendrites by fast spikes in the hippocampus in vivo. Proceedings of the National Academy of Sciences of the United States of America. vol 93. issue 18. 1996-10-24. PMID:8790432. |
these findings indicate that (i) the voltage-dependent calcium influx into the dendrites is under the control of inhibitory neurons and (ii) the temporal coincidence of synaptic depolarization and activation of voltage-dependent calcium conductances by the backpropagating spikes during sharp wave bursts may be critical for synaptic plasticity in the intact hippocampus. |
1996-10-24 |
2023-08-12 |
rat |
R R Johnson, X Jiang, A Burkhalte. Regional and laminar differences in synaptic localization of NMDA receptor subunit NR1 splice variants in rat visual cortex and hippocampus. The Journal of comparative neurology. vol 368. issue 3. 1996-10-23. PMID:8725343. |
we have, therefore, examined the regional and laminar distribution of nr1, the essential subunit of the nmda receptor, in two regions in which synaptic plasticity has been most thoroughly studied: primary visual cortex and hippocampus. |
1996-10-23 |
2023-08-12 |
rat |
I Cavuş, P H Koo, T J Teyle. Inhibition of long-term potentiation development in rat hippocampal slice by alpha 2-macroglobulin, an acute-phase protein in the brain. Journal of neuroscience research. vol 43. issue 3. 1996-10-08. PMID:8714517. |
since neurotrophic factors are known to be involved in synaptic plasticity, we tested the effect of both the native and methylamine-activated (ma-alpha 2m) forms of alpha 2m on long-term potentiation (ltp) in area ca1 of adult rat hippocampal slice. |
1996-10-08 |
2023-08-12 |
human |
G J Biessels, A Kamal, G M Ramakers, I J Urban, B M Spruijt, D W Erkelens, W H Gispe. Place learning and hippocampal synaptic plasticity in streptozotocin-induced diabetic rats. Diabetes. vol 45. issue 9. 1996-10-08. PMID:8772732. |
place learning and hippocampal synaptic plasticity in streptozotocin-induced diabetic rats. |
1996-10-08 |
2023-08-12 |
rat |
G J Biessels, A Kamal, G M Ramakers, I J Urban, B M Spruijt, D W Erkelens, W H Gispe. Place learning and hippocampal synaptic plasticity in streptozotocin-induced diabetic rats. Diabetes. vol 45. issue 9. 1996-10-08. PMID:8772732. |
electrophysiological testing consisted of in vitro assessment of hippocampal long-term potentiation (ltp), an activity-dependent form of synaptic plasticity, which is believed to be related to the cellular mechanisms of learning and memory. |
1996-10-08 |
2023-08-12 |
rat |