| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E M O'Kane, T W Stone, B J Morri. Increased long-term potentiation in the CA1 region of rat hippocampus via modulation of GTPase signalling or inhibition of Rho kinase. Neuropharmacology. vol 46. issue 6. 2004-06-21. PMID:15033347. |
this provides strong evidence that gtpases are important mediators of synaptic plasticity, and demonstrates that rho-kinase acts to reduce the degree of plasticity at hippocampal synapses during ltp. |
2004-06-21 |
2023-08-12 |
rat |
| Anna Kloda, John D Clements, Richard J Lewis, David J Adam. Adenosine triphosphate acts as both a competitive antagonist and a positive allosteric modulator at recombinant N-methyl-D-aspartate receptors. Molecular pharmacology. vol 65. issue 6. 2004-06-21. PMID:15155832. |
both neurotransmitters regulate synaptic plasticity and long-term potentiation in hippocampal neurons. |
2004-06-21 |
2023-08-12 |
xenopus_laevis |
| Motoharu Yoshida, Hatsuo Hayash. Regulation of spontaneous rhythmic activity and organization of pacemakers as memory traces by spike-timing-dependent synaptic plasticity in a hippocampal model. Physical review. E, Statistical, nonlinear, and soft matter physics. vol 69. issue 1 Pt 1. 2004-06-14. PMID:14995650. |
regulation of spontaneous rhythmic activity and organization of pacemakers as memory traces by spike-timing-dependent synaptic plasticity in a hippocampal model. |
2004-06-14 |
2023-08-12 |
human |
| Armen Sargsyan, Albert Melkonyan, Hovhannes Mkrtchian, Costas Papatheodoropoulos, George Kostopoulo. A computer model of field potential responses for the study of short-term plasticity in hippocampus. Journal of neuroscience methods. vol 135. issue 1-2. 2004-06-07. PMID:15020102. |
the model field potentials in response to various randomly generated and real (derived from recorded ca3 unit activity) long stimulating trains were calculated, illustrating that short-term plasticity with the observed characteristics could play specific roles in frequency processing in hippocampus and thus providing a new tool for the theoretical study of activity-dependent synaptic plasticity. |
2004-06-07 |
2023-08-12 |
human |
| Christoph Schmidt-Hieber, Peter Jonas, Josef Bischofberge. Enhanced synaptic plasticity in newly generated granule cells of the adult hippocampus. Nature. vol 429. issue 6988. 2004-06-02. PMID:15107864. |
enhanced synaptic plasticity in newly generated granule cells of the adult hippocampus. |
2004-06-02 |
2023-08-12 |
Not clear |
| Ya Yang, Xigeng Zheng, Yongfu Wang, Jun Cao, Zhifang Dong, Jingxia Cai, Nan Sui, Lin X. Stress enables synaptic depression in CA1 synapses by acute and chronic morphine: possible mechanisms for corticosterone on opiate addiction. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 10. 2004-05-28. PMID:15014116. |
we have studied the effect of stress with morphine on synaptic plasticity in the ca1 region of the hippocampus in vivo and on a delayed-escape paradigm of the morris water maze. |
2004-05-28 |
2023-08-12 |
Not clear |
| Ya Yang, Xigeng Zheng, Yongfu Wang, Jun Cao, Zhifang Dong, Jingxia Cai, Nan Sui, Lin X. Stress enables synaptic depression in CA1 synapses by acute and chronic morphine: possible mechanisms for corticosterone on opiate addiction. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 10. 2004-05-28. PMID:15014116. |
these results suggest that hippocampal synaptic plasticity may play a significant role in the effects of stress or glucocorticoids on opiate addiction. |
2004-05-28 |
2023-08-12 |
Not clear |
| Carlos A Saura, Se-Young Choi, Vassilios Beglopoulos, Seema Malkani, Dawei Zhang, B S Shankaranarayana Rao, Sumantra Chattarji, Raymond J Kelleher, Eric R Kandel, Karen Duff, Alfredo Kirkwood, Jie She. Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration. Neuron. vol 42. issue 1. 2004-05-27. PMID:15066262. |
here we demonstrate that conditional double knockout mice lacking both presenilins in the postnatal forebrain exhibit impairments in hippocampal memory and synaptic plasticity. |
2004-05-27 |
2023-08-12 |
mouse |
| Ipe Ninan, Ottavio Aranci. Presynaptic CaMKII is necessary for synaptic plasticity in cultured hippocampal neurons. Neuron. vol 42. issue 1. 2004-05-27. PMID:15066270. |
presynaptic camkii is necessary for synaptic plasticity in cultured hippocampal neurons. |
2004-05-27 |
2023-08-12 |
Not clear |
| Ipe Ninan, Ottavio Aranci. Presynaptic CaMKII is necessary for synaptic plasticity in cultured hippocampal neurons. Neuron. vol 42. issue 1. 2004-05-27. PMID:15066270. |
thus, the present results conclusively prove that presynaptic camkii is essential for synaptic plasticity in cultured hippocampal neurons. |
2004-05-27 |
2023-08-12 |
Not clear |
| b' Joe Guillaume Pelletier, John Apergis, Denis Par\\xc3\\xa. Low-probability transmission of neocortical and entorhinal impulses through the perirhinal cortex. Journal of neurophysiology. vol 91. issue 5. 2004-05-25. PMID:15069098.' |
one model of episodic memory posits that during slow-wave sleep (sws), the synchronized discharges of hippocampal neurons in relation to sharp waves "replay" activity patterns that occurred during the waking state, facilitating synaptic plasticity in the neocortex. |
2004-05-25 |
2023-08-12 |
Not clear |
| Bertalan K Andrásfalvy, Mark A Smith, Thilo Borchardt, Rolf Sprengel, Jeffrey C Mage. Impaired regulation of synaptic strength in hippocampal neurons from GluR1-deficient mice. The Journal of physiology. vol 552. issue Pt 1. 2004-05-24. PMID:12878757. |
because of this importance in associative plasticity, we sought to examine the role of these receptors in other forms of synaptic plasticity in the hippocampus. |
2004-05-24 |
2023-08-12 |
mouse |
| Rose-Marie Vouimba, Dan Yaniv, David Diamond, Gal Richter-Levi. Effects of inescapable stress on LTP in the amygdala versus the dentate gyrus of freely behaving rats. The European journal of neuroscience. vol 19. issue 7. 2004-05-24. PMID:15078562. |
stress impairs hippocampal long-term potentiation (ltp), a model of synaptic plasticity that is assumed to underlie memory formation. |
2004-05-24 |
2023-08-12 |
rat |
| Amanda J Roberts, Thomas Krucker, Coree L Levy, Kristen A Slanina, J Gregor Sutcliffe, Peter B Hedlun. Mice lacking 5-HT receptors show specific impairments in contextual learning. The European journal of neuroscience. vol 19. issue 7. 2004-05-24. PMID:15078565. |
in addition, we demonstrate that 5-ht(7) receptor knockout mice display decreased long-term synaptic plasticity within the ca1 region of the hippocampus. |
2004-05-24 |
2023-08-12 |
mouse |
| Lidong Liu, Tak Pan Wong, Mario F Pozza, Kurt Lingenhoehl, Yushan Wang, Morgan Sheng, Yves P Auberson, Yu Tian Wan. Role of NMDA receptor subtypes in governing the direction of hippocampal synaptic plasticity. Science (New York, N.Y.). vol 304. issue 5673. 2004-05-21. PMID:15143284. |
role of nmda receptor subtypes in governing the direction of hippocampal synaptic plasticity. |
2004-05-21 |
2023-08-12 |
Not clear |
| Kaori Tachibana, Machiko Matsumoto, Hiroko Togashi, Taku Kojima, Yuji Morimoto, Osamu Kemmotsu, Mitsuhiro Yoshiok. Milnacipran, a serotonin and noradrenaline reuptake inhibitor, suppresses long-term potentiation in the rat hippocampal CA1 field via 5-HT1A receptors and alpha 1-adrenoceptors. Neuroscience letters. vol 357. issue 2. 2004-05-13. PMID:15036582. |
in other words, functional interaction between the serotonergic and noradrenergic neuronal systems is involved in alteration of the hippocampal synaptic plasticity, which may be implicated in the snri-induced therapeutic effect on psychiatric disorders. |
2004-05-13 |
2023-08-12 |
rat |
| R Molteni, A Wu, S Vaynman, Z Ying, R J Barnard, F Gómez-Pinill. Exercise reverses the harmful effects of consumption of a high-fat diet on synaptic and behavioral plasticity associated to the action of brain-derived neurotrophic factor. Neuroscience. vol 123. issue 2. 2004-05-12. PMID:14698750. |
a diet high in total fat (hf) reduces hippocampal levels of brain-derived neurotrophic factor (bdnf), a crucial modulator of synaptic plasticity, and a predictor of learning efficacy. |
2004-05-12 |
2023-08-12 |
Not clear |
| E Dalfó, T Gómez-Isla, J L Rosa, M Nieto Bodelón, M Cuadrado Tejedor, M Barrachina, S Ambrosio, I Ferre. Abnormal alpha-synuclein interactions with Rab proteins in alpha-synuclein A30P transgenic mice. Journal of neuropathology and experimental neurology. vol 63. issue 4. 2004-05-12. PMID:15099020. |
this rationale is consistent with previous data showing that short-term hippocampal synaptic plasticity is altered and that alpha-synuclein accumulates in the cytoplasm of neurons in tg mice. |
2004-05-12 |
2023-08-12 |
mouse |
| Zhihua Wu, Yoko Yamaguch. Input-dependent learning rule for the memory of spatiotemporal sequences in hippocampal network with theta phase precession. Biological cybernetics. vol 90. issue 2. 2004-05-10. PMID:14999478. |
theta phase precession in rat hippocampal place cells is hypothesized to contribute to memory encoding of running experience in the sense that it provides the ideal timing for synaptic plasticity and enables the asymmetric associative connections under the hebbian learning rule with asymmetric time window (yamaguchi 2003). |
2004-05-10 |
2023-08-12 |
rat |
| Catherine Harris-Cerruti, Ariel Kamsler, Batia Kaplan, Bruce Lamb, Menahem Segal, Yoram Grone. Functional and morphological alterations in compound transgenic mice overexpressing Cu/Zn superoxide dismutase and amyloid precursor protein [correction]. The European journal of neuroscience. vol 19. issue 5. 2004-05-05. PMID:15016076. |
expression of long-term potentiation in hippocampal slices was impaired in both tg-sod and tg-app-sod mice, but not in tg-app mice, indicating that increased app by itself did not affect in vitro synaptic plasticity. |
2004-05-05 |
2023-08-12 |
mouse |