| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Faridis Serrano, Eric Klan. Reactive oxygen species and synaptic plasticity in the aging hippocampus. Ageing research reviews. vol 3. issue 4. 2005-04-12. PMID:15541710. |
long-term potentiation (ltp), a form of synaptic plasticity that has been proposed as a biological substrate for learning and memory, has been used to examine age-related changes in hippocampal synaptic plasticity. |
2005-04-12 |
2023-08-12 |
mouse |
| W Bryan Smith, Shelley R Starck, Richard W Roberts, Erin M Schuma. Dopaminergic stimulation of local protein synthesis enhances surface expression of GluR1 and synaptic transmission in hippocampal neurons. Neuron. vol 45. issue 5. 2005-04-12. PMID:15748851. |
in the hippocampus, dopaminergic signaling is thought to play a key role in protein synthesis-dependent forms of synaptic plasticity. |
2005-04-12 |
2023-08-12 |
Not clear |
| Ulrich H Schröder, Franz J Hock, Klaus Wirth, Heinrich C Englert, Klaus G Reyman. The ATP-regulated K+-channel inhibitor HMR-1372 affects synaptic plasticity in hippocampal slices. European journal of pharmacology. vol 502. issue 1-2. 2005-04-08. PMID:15464094. |
the atp-regulated k+-channel inhibitor hmr-1372 affects synaptic plasticity in hippocampal slices. |
2005-04-08 |
2023-08-12 |
rat |
| Ingrid Y C Liu, W Ernest Lyons, Laura A Mamounas, Richard F Thompso. Brain-derived neurotrophic factor plays a critical role in contextual fear conditioning. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 36. 2005-04-05. PMID:15356210. |
because bdnf is involved in synaptic transmission and contextual learning is hippocampal dependent, we hypothesized that this deficit is attributable to abnormal bdnf-modulated synaptic plasticity in the hippocampus. |
2005-04-05 |
2023-08-12 |
mouse |
| Eija Koponen, Merja Lakso, Eero Castré. Overexpression of the full-length neurotrophin receptor trkB regulates the expression of plasticity-related genes in mouse brain. Brain research. Molecular brain research. vol 130. issue 1-2. 2005-03-30. PMID:15519679. |
significant body of evidence indicates an important role for brain-derived neurotrophic factor (bdnf) in the hippocampal synaptic plasticity; however, the exact mechanisms how the bdnf signal is converted to plastic changes during memory processes are under an intense investigation. |
2005-03-30 |
2023-08-12 |
mouse |
| Bianca C Wittmann, Björn H Schott, Sebastian Guderian, Julietta U Frey, Hans-Jochen Heinze, Emrah Düze. Reward-related FMRI activation of dopaminergic midbrain is associated with enhanced hippocampus-dependent long-term memory formation. Neuron. vol 45. issue 3. 2005-03-29. PMID:15694331. |
this improved synaptic plasticity is hypothesized to be associated with better memory consolidation in the hippocampus. |
2005-03-29 |
2023-08-12 |
Not clear |
| S Yamamoto, T Kanno, T Nagata, T Yaguchi, A Tanaka, T Nishizak. The linoleic acid derivative FR236924 facilitates hippocampal synaptic transmission by enhancing activity of presynaptic alpha7 acetylcholine receptors on the glutamatergic terminals. Neuroscience. vol 130. issue 1. 2005-03-22. PMID:15561436. |
this may provide evidence for a link between cis-unsaturated free fatty acids and presynaptic alpha7 ach receptors in hippocampal synaptic plasticity. |
2005-03-22 |
2023-08-12 |
rat |
| Yan-You Huang, Eric R Kande. Theta frequency stimulation up-regulates the synaptic strength of the pathway from CA1 to subiculum region of hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 1. 2005-03-10. PMID:15623558. |
we have examined synaptic plasticity in the synaptic pathway between the ca1 pyramidal cells and the sb in hippocampal slices and compared it under the same experimental condition with the synaptic plasticity in shaffer collateral pathway (ca3-ca1). |
2005-03-10 |
2023-08-12 |
Not clear |
| Chu Chen, Nicolas G Baza. Endogenous PGE2 regulates membrane excitability and synaptic transmission in hippocampal CA1 pyramidal neurons. Journal of neurophysiology. vol 93. issue 2. 2005-03-10. PMID:15653788. |
recent evidence that cox-2, which is expressed in postsynaptic dendritic spines, regulates pge2 signaling in activity-dependent long-term synaptic plasticity at hippocampal perforant path-dentate granule cell synapses, suggests an important role of the cox-2-generated pge2 in synaptic signaling. |
2005-03-10 |
2023-08-12 |
rat |
| Anita Cybulska-Klosowicz, Nektarios K Mazarakis, Anton Van Dellen, Colin Blakemore, Anthony J Hannan, Malgorzata Kossu. Impaired learning-dependent cortical plasticity in Huntington's disease transgenic mice. Neurobiology of disease. vol 17. issue 3. 2005-03-07. PMID:15571978. |
although changes in synaptic plasticity were shown within the hippocampus and striatum of hd transgenic mice, there are no studies considering neocortical synaptic plasticity abnormalities in hd. |
2005-03-07 |
2023-08-12 |
mouse |
| J E Gresack, K M Fric. Environmental enrichment reduces the mnemonic and neural benefits of estrogen. Neuroscience. vol 128. issue 3. 2005-03-04. PMID:15381276. |
the results suggest that: (1) estrogen benefits object and working memory more in mice raised in non-enriched environments than in those raised in enriched environments, and (2) the changes induced by estrogen and/or enrichment may be associated with alterations in hippocampal synaptic plasticity. |
2005-03-04 |
2023-08-12 |
mouse |
| Shoshanna Vaynman, Zhe Ying, Fernando Gomez-Pinill. Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition. The European journal of neuroscience. vol 20. issue 10. 2005-03-01. PMID:15548201. |
hippocampal bdnf mediates the efficacy of exercise on synaptic plasticity and cognition. |
2005-03-01 |
2023-08-12 |
Not clear |
| A Sliwinski, F P Monnet, M Schumacher, M P Morin-Suru. Pregnenolone sulfate enhances long-term potentiation in CA1 in rat hippocampus slices through the modulation of N-methyl-D-aspartate receptors. Journal of neuroscience research. vol 78. issue 5. 2005-02-28. PMID:15505794. |
the present study employs rat hippocampal slices to investigate the ability of pregs to modulate long-term potentiation (ltp), a phenomenon considered as a model of synaptic plasticity related to memory processes. |
2005-02-28 |
2023-08-12 |
rat |
| F Pedrosa Gi. [Current aspects of psychosomatic and endocrine stress research]. Deutsche medizinische Wochenschrift (1946). vol 130. issue 3. 2005-02-14. PMID:15650960. |
stress induced different functional (increase of catecholamines and glucocorticoids) and structural changes in brain regions such as the hippocampus, with suppression of adult neurogenesis and synaptic plasticity. |
2005-02-14 |
2023-08-12 |
Not clear |
| Inbal Israely, Rui M Costa, Cui Wei Xie, Alcino J Silva, Kenneth S Kosik, Xin Li. Deletion of the neuron-specific protein delta-catenin leads to severe cognitive and synaptic dysfunction. Current biology : CB. vol 14. issue 18. 2005-02-07. PMID:15380068. |
furthermore, mutant mice display a range of abnormalities in hippocampal short-term and long-term synaptic plasticity. |
2005-02-07 |
2023-08-12 |
mouse |
| Kazuhito Nakao, Koji Matsuyama, Norio Matsuki, Yuji Ikegay. Amygdala stimulation modulates hippocampal synaptic plasticity. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 39. 2005-02-07. PMID:15381775. |
amygdala stimulation modulates hippocampal synaptic plasticity. |
2005-02-07 |
2023-08-12 |
Not clear |
| Kazuhito Nakao, Koji Matsuyama, Norio Matsuki, Yuji Ikegay. Amygdala stimulation modulates hippocampal synaptic plasticity. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 39. 2005-02-07. PMID:15381775. |
these results represent a high-order dimension of heterosynaptic modulations of hippocampal synaptic plasticity. |
2005-02-07 |
2023-08-12 |
Not clear |
| Thérèse M Jay, Cyril Rocher, Maïte Hotte, Laurent Naudon, Hirac Gurden, Michael Speddin. Plasticity at hippocampal to prefrontal cortex synapses is impaired by loss of dopamine and stress: importance for psychiatric diseases. Neurotoxicity research. vol 6. issue 3. 2005-01-31. PMID:15325962. |
the direct hippocampal to prefrontal cortex pathway and its changes in synaptic plasticity is a useful framework for investigating the functional operations of hippocampal-prefrontal cortex communication in cognitive functions. |
2005-01-31 |
2023-08-12 |
human |
| Robert K McNamara, Robert H Leno. Acute restraint stress reduces protein kinase C gamma in the hippocampus of C57BL/6 but not DBA/2 mice. Neuroscience letters. vol 368. issue 3. 2005-01-31. PMID:15364414. |
acute stress has been shown to negatively affect hippocampal synaptic plasticity, and the present study examined the effect of acute stress on pkc gamma expression/subcellular distribution by quantitative western blotting in two inbred mouse strains (c57bl/6j versus dba/2j) with established differences in hippocampal plasticity. |
2005-01-31 |
2023-08-12 |
mouse |
| Robert K McNamara, Robert H Leno. Acute restraint stress reduces protein kinase C gamma in the hippocampus of C57BL/6 but not DBA/2 mice. Neuroscience letters. vol 368. issue 3. 2005-01-31. PMID:15364414. |
the role of stress-induced regulation of hippocampal pkc gamma expression in hippocampal synaptic plasticity is discussed. |
2005-01-31 |
2023-08-12 |
mouse |