| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jonathan M Levenson, Tania L Roth, Farah D Lubin, Courtney A Miller, I-Chia Huang, Priyanka Desai, Lauren M Malone, J David Sweat. Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus. The Journal of biological chemistry. vol 281. issue 23. 2006-08-23. PMID:16606618. |
evidence that dna (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus. |
2006-08-23 |
2023-08-12 |
Not clear |
| Jonathan M Levenson, Tania L Roth, Farah D Lubin, Courtney A Miller, I-Chia Huang, Priyanka Desai, Lauren M Malone, J David Sweat. Evidence that DNA (cytosine-5) methyltransferase regulates synaptic plasticity in the hippocampus. The Journal of biological chemistry. vol 281. issue 23. 2006-08-23. PMID:16606618. |
we found that the dna within promoters for reelin and brain-derived neurotrophic factor, genes implicated in the induction of synaptic plasticity in the adult hippocampus, exhibited rapid and dramatic changes in cytosine methylation when dnmt activity was inhibited. |
2006-08-23 |
2023-08-12 |
Not clear |
| Mélissa Farinelli, Olivier Deschaux, Sandrine Hugues, Aurélie Thevenet, René Garci. Hippocampal train stimulation modulates recall of fear extinction independently of prefrontal cortex synaptic plasticity and lesions. Learning & memory (Cold Spring Harbor, N.Y.). vol 13. issue 3. 2006-08-23. PMID:16741284. |
hippocampal train stimulation modulates recall of fear extinction independently of prefrontal cortex synaptic plasticity and lesions. |
2006-08-23 |
2023-08-12 |
rat |
| Julie Baratier, Leticia Peris, Jacques Brocard, Sylvie Gory-Fauré, Fabrice Dufour, Christophe Bosc, Anne Fourest-Lieuvin, Laurent Blanchoin, Paul Salin, Didier Job, Annie Andrieu. Phosphorylation of microtubule-associated protein STOP by calmodulin kinase II. The Journal of biological chemistry. vol 281. issue 28. 2006-08-21. PMID:16651267. |
stop suppression in mice induces synaptic defects affecting both short and long term synaptic plasticity in hippocampal neurons. |
2006-08-21 |
2023-08-12 |
mouse |
| Christopher J Davis, Peter C Meighan, Ping Taishi, James M Krueger, Joseph W Harding, John W Wrigh. REM sleep deprivation attenuates actin-binding protein cortactin: a link between sleep and hippocampal plasticity. Neuroscience letters. vol 400. issue 3. 2006-08-18. PMID:16533564. |
hippocampal cortactin levels, phosphorylation, and processing appear to be altered during learning and long-term potentiation (ltp); consistent with a role for cortactin in the dendritic restructuring that accompanies synaptic plasticity. |
2006-08-18 |
2023-08-12 |
rat |
| Christopher J Davis, Peter C Meighan, Ping Taishi, James M Krueger, Joseph W Harding, John W Wrigh. REM sleep deprivation attenuates actin-binding protein cortactin: a link between sleep and hippocampal plasticity. Neuroscience letters. vol 400. issue 3. 2006-08-18. PMID:16533564. |
thus, these data support a functional link between rems and cytoskeletal reorganization in the hippocampus, a process that is essential for synaptic plasticity. |
2006-08-18 |
2023-08-12 |
rat |
| Shu-Ming Huang, Akihiro Mouri, Hideko Kokubo, Ryuichi Nakajima, Takahiro Suemoto, Makoto Higuchi, Matthias Staufenbiel, Yukihiro Noda, Haruyasu Yamaguchi, Toshitaka Nabeshima, Takaomi C Saido, Nobuhisa Iwat. Neprilysin-sensitive synapse-associated amyloid-beta peptide oligomers impair neuronal plasticity and cognitive function. The Journal of biological chemistry. vol 281. issue 26. 2006-08-18. PMID:16636059. |
we also examined hippocampal synaptic plasticity using an in vivo recording technique and cognitive function using a battery of learning and memory behavior tests, including y-maze, novel-object recognition, morris water maze, and contextual fear conditioning tests at the age of 13-16 weeks. |
2006-08-18 |
2023-08-12 |
mouse |
| Shu-Ming Huang, Akihiro Mouri, Hideko Kokubo, Ryuichi Nakajima, Takahiro Suemoto, Makoto Higuchi, Matthias Staufenbiel, Yukihiro Noda, Haruyasu Yamaguchi, Toshitaka Nabeshima, Takaomi C Saido, Nobuhisa Iwat. Neprilysin-sensitive synapse-associated amyloid-beta peptide oligomers impair neuronal plasticity and cognitive function. The Journal of biological chemistry. vol 281. issue 26. 2006-08-18. PMID:16636059. |
we present direct experimental evidence that reduced activity of neprilysin, the major abeta-degrading enzyme, in the brain elevates oligomeric forms of abeta at the synapses and leads to impaired hippocampal synaptic plasticity and cognitive function before the appearance of amyloid plaque load. |
2006-08-18 |
2023-08-12 |
mouse |
| P V Nguye. Comparative plasticity of brain synapses in inbred mouse strains. The Journal of experimental biology. vol 209. issue Pt 12. 2006-08-16. PMID:16731805. |
many such analyses have focused on synaptic plasticity in the hippocampus because of the critical roles of this brain structure in the formation and consolidation of long-term memories. |
2006-08-16 |
2023-08-12 |
mouse |
| P V Nguye. Comparative plasticity of brain synapses in inbred mouse strains. The Journal of experimental biology. vol 209. issue Pt 12. 2006-08-16. PMID:16731805. |
comparative electrophysiological data obtained from several inbred mouse strains are reviewed here to highlight the following key notions: (1) synaptic plasticity is influenced by the genetic backgrounds of inbred mice; (2) the plasticity of hippocampal synapses in inbred mice is ;tuned' to particular temporal patterns of activity; (3) long-term potentiation, but not long-term depression, is a cellular correlate of behavioural memory performance in some strains; (4) synaptic phenotyping of inbred mouse strains can identify cellular models of memory impairment that can be used to elucidate mechanisms that may cause specific memory deficits. |
2006-08-16 |
2023-08-12 |
mouse |
| Neal Lemon, Denise Manahan-Vaugha. Dopamine D1/D5 receptors gate the acquisition of novel information through hippocampal long-term potentiation and long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 29. 2006-08-14. PMID:16855100. |
hippocampal synaptic plasticity, in the form of long-term potentiation (ltp) and long-term depression (ltd), has been implicated in both spatial memory formation as well as novelty acquisition. |
2006-08-14 |
2023-08-12 |
rat |
| Neal Lemon, Denise Manahan-Vaugha. Dopamine D1/D5 receptors gate the acquisition of novel information through hippocampal long-term potentiation and long-term depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 29. 2006-08-14. PMID:16855100. |
specific types of learning are associated with specific types of hippocampal synaptic plasticity. |
2006-08-14 |
2023-08-12 |
rat |
| C Pandis, E Sotiriou, E Kouvaras, E Asprodini, C Papatheodoropoulos, F Angelato. Differential expression of NMDA and AMPA receptor subunits in rat dorsal and ventral hippocampus. Neuroscience. vol 140. issue 1. 2006-08-10. PMID:16542781. |
this could be related to the lower ability of ventral hippocampus for long-term synaptic plasticity and to the higher involvement of the nmda receptors in the epileptiform discharges, observed in ventral hippocampus compared with dorsal hippocampus. |
2006-08-10 |
2023-08-12 |
rat |
| Eleanor J Bull, Veronica Porkess, Michael Rigby, Peter H Hutson, Kevin C F Fon. Pre-treatment with 3,4-methylenedioxymethamphetamine (MDMA) causes long-lasting changes in 5-HT2A receptor-mediated glucose utilization in the rat brain. Journal of psychopharmacology (Oxford, England). vol 20. issue 2. 2006-08-09. PMID:16510485. |
thus, brief exposure of young rats to an mdma regimen previously shown to cause anxiety-like behaviour and modest serotonergic neurotoxicity (bull et al., 2004) increased doi-induced energy metabolism in the nucleus accumbens and tended to increase metabolism in other brain regions, including the hippocampus, consistent with the induction of long-term brain region specific changes in synaptic plasticity. |
2006-08-09 |
2023-08-12 |
rat |
| Aiguo Wu, Zhe Ying, Fernando Gomez-Pinill. Oxidative stress modulates Sir2alpha in rat hippocampus and cerebral cortex. The European journal of neuroscience. vol 23. issue 10. 2006-08-04. PMID:16817860. |
a diet high in saturated fat and sucrose, which has been shown in rodents to reduce synaptic plasticity and cognition, decreased sir2alpha levels in the hippocampus and cerebral cortex, in proportion to an increase in protein oxidation. |
2006-08-04 |
2023-08-12 |
rat |
| Jaime L Tartar, Christopher P Ward, James T McKenna, Mahesh Thakkar, Elda Arrigoni, Robert W McCarley, Ritchie E Brown, Robert E Strecke. Hippocampal synaptic plasticity and spatial learning are impaired in a rat model of sleep fragmentation. The European journal of neuroscience. vol 23. issue 10. 2006-08-04. PMID:16817877. |
hippocampal synaptic plasticity and spatial learning are impaired in a rat model of sleep fragmentation. |
2006-08-04 |
2023-08-12 |
rat |
| Mehul H Nagarsheth, Alex Viehman, Sara M Lippa, Carol F Lipp. Notch-1 immunoexpression is increased in Alzheimer's and Pick's disease. Journal of the neurological sciences. vol 244. issue 1-2. 2006-07-28. PMID:16473372. |
however, notch-1 is also expressed in the adult brain, in regions with high synaptic plasticity, particularly the hippocampus. |
2006-07-28 |
2023-08-12 |
Not clear |
| S Vaynman, Z Ying, A Wu, F Gomez-Pinill. Coupling energy metabolism with a mechanism to support brain-derived neurotrophic factor-mediated synaptic plasticity. Neuroscience. vol 139. issue 4. 2006-07-26. PMID:16580138. |
we infused 1,25-dihydroxyvitamin d3, a modulator of energy metabolism, directly into the hippocampus during 3 days of voluntary wheel running and measured its effects on brain-derived neurotrophic factor-mediated synaptic plasticity. |
2006-07-26 |
2023-08-12 |
Not clear |
| S Vaynman, Z Ying, A Wu, F Gomez-Pinill. Coupling energy metabolism with a mechanism to support brain-derived neurotrophic factor-mediated synaptic plasticity. Neuroscience. vol 139. issue 4. 2006-07-26. PMID:16580138. |
our results reveal a fundamental mechanism by which key elements of energy metabolism may modulate the substrates of hippocampal synaptic plasticity. |
2006-07-26 |
2023-08-12 |
Not clear |
| Sara C Shalin, Caterina M Hernandez, Michele K Dougherty, Deborah K Morrison, J David Sweat. Kinase suppressor of Ras1 compartmentalizes hippocampal signal transduction and subserves synaptic plasticity and memory formation. Neuron. vol 50. issue 5. 2006-07-21. PMID:16731514. |
kinase suppressor of ras1 compartmentalizes hippocampal signal transduction and subserves synaptic plasticity and memory formation. |
2006-07-21 |
2023-08-12 |
Not clear |