| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ulrike Kemmerling, Pablo Muñoz, Marioly Müller, Gina Sánchez, María L Aylwin, Eric Klann, M Angélica Carrasco, Cecilia Hidalg. Calcium release by ryanodine receptors mediates hydrogen peroxide-induced activation of ERK and CREB phosphorylation in N2a cells and hippocampal neurons. Cell calcium. vol 41. issue 5. 2007-06-18. PMID:17074386. |
we propose that ryanodine receptor stimulation by activity-generated redox species produces calcium release signals that may contribute significantly to hippocampal synaptic plasticity, including plasticity that requires long-lasting erk-dependent creb phosphorylation. |
2007-06-18 |
2023-08-12 |
mouse |
| Margarida V Caldeira, Carlos V Melo, Daniela B Pereira, Ricardo Carvalho, Susana S Correia, Donald S Backos, Ana Luísa Carvalho, José A Esteban, Carlos B Duart. Brain-derived neurotrophic factor regulates the expression and synaptic delivery of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor subunits in hippocampal neurons. The Journal of biological chemistry. vol 282. issue 17. 2007-06-14. PMID:17337442. |
brain-derived neurotrophic factor (bdnf) plays an important role in synaptic plasticity in the hippocampus, but the mechanisms involved are not fully understood. |
2007-06-14 |
2023-08-12 |
Not clear |
| O V Forlenza, E L Schaeffer, W F Gatta. The role of phospholipase A2 in neuronal homeostasis and memory formation: implications for the pathogenesis of Alzheimer's disease. Journal of neural transmission (Vienna, Austria : 1996). vol 114. issue 2. 2007-06-13. PMID:17131232. |
in rat hippocampal slices, pla(2) has been implicated in mechanisms of synaptic plasticity. |
2007-06-13 |
2023-08-12 |
rat |
| T Verina, C A Rohde, T R Guilart. Environmental lead exposure during early life alters granule cell neurogenesis and morphology in the hippocampus of young adult rats. Neuroscience. vol 145. issue 3. 2007-06-13. PMID:17276012. |
exposure to environmentally relevant levels of lead (pb(2+)) during early life produces deficits in hippocampal synaptic plasticity in the form of long-term potentiation (ltp) and spatial learning in young adult rats [nihei mk, desmond nl, mcglothan jl, kuhlmann ac, guilarte tr (2000) n-methyl-d-aspartate receptor subunit changes are associated with lead-induced deficits of long-term potentiation and spatial learning. |
2007-06-13 |
2023-08-12 |
rat |
| Daoying Hu, Eric Klann, Edda Thiel. Superoxide dismutase and hippocampal function: age and isozyme matter. Antioxidants & redox signaling. vol 9. issue 2. 2007-06-12. PMID:17115934. |
transgenic mice overexpressing different isozymes of sod have been used to study the effect of sod overexpression on hippocampal synaptic plasticity and hippocampus-dependent learning and memory. |
2007-06-12 |
2023-08-12 |
mouse |
| Cecilia Hidalgo, M Angélica Carrasco, Pablo Muñoz, Marco T Núñe. A role for reactive oxygen/nitrogen species and iron on neuronal synaptic plasticity. Antioxidants & redox signaling. vol 9. issue 2. 2007-06-12. PMID:17115937. |
the authors also present recent results showing that, in hippocampal neurons, ros/rns, including ros generated by iron through the fenton reaction, stimulate ryanodine receptor-mediated calcium release, and how the resulting calcium signals activate the signaling cascades that lead to the transcription of genes known to participate in synaptic plasticity. |
2007-06-12 |
2023-08-12 |
human |
| Huifang Ma, Sylvain Lesné, Linda Kotilinek, Jill V Steidl-Nichols, Mathew Sherman, Linda Younkin, Steven Younkin, Colleen Forster, Nicolas Sergeant, André Delacourte, Robert Vassar, Martin Citron, Paulo Kofuji, Linda M Boland, Karen H Ash. Involvement of beta-site APP cleaving enzyme 1 (BACE1) in amyloid precursor protein-mediated enhancement of memory and activity-dependent synaptic plasticity. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 19. 2007-06-07. PMID:17470798. |
we showed enhanced synaptic plasticity in the hippocampus that depends on prior synaptic activity. |
2007-06-07 |
2023-08-12 |
mouse |
| John F MacDonald, Michael F Jackson, Michael A Beazel. G protein-coupled receptors control NMDARs and metaplasticity in the hippocampus. Biochimica et biophysica acta. vol 1768. issue 4. 2007-05-30. PMID:17261268. |
long-term potentiation (ltp) and long-term depression (ltd) are the major forms of functional synaptic plasticity observed at ca1 synapses of the hippocampus. |
2007-05-30 |
2023-08-12 |
Not clear |
| Christian Holscher, Simon Gengler, Victor A Gault, Patrick Harriott, Hanspeter A Mallo. Soluble beta-amyloid[25-35] reversibly impairs hippocampal synaptic plasticity and spatial learning. European journal of pharmacology. vol 561. issue 1-3. 2007-05-22. PMID:17320856. |
soluble beta-amyloid[25-35] reversibly impairs hippocampal synaptic plasticity and spatial learning. |
2007-05-22 |
2023-08-12 |
Not clear |
| David A Costa, Jennifer R Cracchiolo, Adam D Bachstetter, Tiffany F Hughes, Kelly R Bales, Steven M Paul, Ronald F Mervis, Gary W Arendash, Huntington Potte. Enrichment improves cognition in AD mice by amyloid-related and unrelated mechanisms. Neurobiology of aging. vol 28. issue 6. 2007-05-17. PMID:16730391. |
microarray analysis revealed large enrichment-induced changes in hippocampal expression of genes/proteins related to abeta sequestration and synaptic plasticity. |
2007-05-17 |
2023-08-12 |
mouse |
| Yantao Zuo, Douglas C Smith, Robert A Jense. Vagus nerve stimulation potentiates hippocampal LTP in freely-moving rats. Physiology & behavior. vol 90. issue 4. 2007-05-17. PMID:17207505. |
these findings suggest that the neural mechanisms underlying the mnemonic effect of vns may involve modulating synaptic plasticity in the hippocampus. |
2007-05-17 |
2023-08-12 |
human |
| Maolei Xiao, Lin Xu, Fernanda Laezza, Kelvin Yamada, Sheng Feng, David M Ornit. Impaired hippocampal synaptic transmission and plasticity in mice lacking fibroblast growth factor 14. Molecular and cellular neurosciences. vol 34. issue 3. 2007-05-15. PMID:17208450. |
to explore the mechanisms that may account for this phenotype, we show that synaptic transmission at hippocampal schaffer collateral-ca1 synapses and short- and long-term potentiation are impaired in fgf14-/- mice, indicating abnormalities in synaptic plasticity. |
2007-05-15 |
2023-08-12 |
mouse |
| T Aihara, Y Abiru, Y Yamazaki, H Watanabe, Y Fukushima, M Tsukad. The relation between spike-timing dependent plasticity and Ca2+ dynamics in the hippocampal CA1 network. Neuroscience. vol 145. issue 1. 2007-05-15. PMID:17223275. |
in our previous study, spike timing dependent synaptic plasticity (stdp) was investigated in the ca1 area of rat hippocampal slices using optical imaging. |
2007-05-15 |
2023-08-12 |
rat |
| Maria Bjarnadottir, Dinah L Misner, Sascha Haverfield-Gross, Silas Bruun, Vignir G Helgason, Hreinn Stefansson, Arnar Sigmundsson, David R Firth, Berit Nielsen, Ragnheidur Stefansdottir, Thomas J Novak, Kari Stefansson, Mark E Gurney, Thorkell Andresso. Neuregulin1 (NRG1) signaling through Fyn modulates NMDA receptor phosphorylation: differential synaptic function in NRG1+/- knock-outs compared with wild-type mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 17. 2007-05-15. PMID:17460065. |
we also demonstrate that short-term synaptic plasticity is altered and theta-burst long-term potentiation is impaired in nrg1+/- mutant mice, and incubation of hippocampal slices from these mice with nrg1 reversed those effects. |
2007-05-15 |
2023-08-12 |
mouse |
| Krisztián A Kovács, Pascal Steullet, Myriam Steinmann, Kim Q Do, Pierre J Magistretti, Olivier Halfon, Jean-René Cardinau. TORC1 is a calcium- and cAMP-sensitive coincidence detector involved in hippocampal long-term synaptic plasticity. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 11. 2007-05-14. PMID:17360587. |
torc1 is a calcium- and camp-sensitive coincidence detector involved in hippocampal long-term synaptic plasticity. |
2007-05-14 |
2023-08-12 |
Not clear |
| Y Oomura, N Hori, T Shiraishi, K Fukunaga, H Takeda, M Tsuji, T Matsumiya, M Ishibashi, S Aou, X L Li, D Kohno, K Uramura, H Sougawa, T Yada, M J Wayner, K Sasak. Leptin facilitates learning and memory performance and enhances hippocampal CA1 long-term potentiation and CaMK II phosphorylation in rats. Peptides. vol 27. issue 11. 2007-05-10. PMID:16914228. |
leptin may also modulate the synaptic plasticity and behavioral performance related to learning and memory since: leptin receptors are found in the hippocampus, and both leptin and its receptor share structural and functional similarities with the interleukin-6 family of cytokines that modulate long-term potentiation (ltp) in the hippocampus. |
2007-05-10 |
2023-08-12 |
rat |
| Y Oomura, N Hori, T Shiraishi, K Fukunaga, H Takeda, M Tsuji, T Matsumiya, M Ishibashi, S Aou, X L Li, D Kohno, K Uramura, H Sougawa, T Yada, M J Wayner, K Sasak. Leptin facilitates learning and memory performance and enhances hippocampal CA1 long-term potentiation and CaMK II phosphorylation in rats. Peptides. vol 27. issue 11. 2007-05-10. PMID:16914228. |
our results show that leptin not only affects hypothalamic functions (such as feeding, thermogenesis, and neuroendocrine status), but also modulates higher nervous functions, such as the behavioral performance related to learning and memory and hippocampal synaptic plasticity. |
2007-05-10 |
2023-08-12 |
rat |
| João M N Duarte, Célia Nogueira, Ken Mackie, Catarina R Oliveira, Rodrigo A Cunha, Attila Köfalv. Increase of cannabinoid CB1 receptor density in the hippocampus of streptozotocin-induced diabetic rats. Experimental neurology. vol 204. issue 1. 2007-05-10. PMID:17222407. |
the hippocampus has a high density of the cannabinoid type 1 receptor (cb(1)r), which has been shown to control several brain functions affected by diabetes, such as synaptic plasticity, glucose utilisation, memory consolidation and cognition, and maturation and survival of hippocampal neurons. |
2007-05-10 |
2023-08-12 |
rat |
| Benedict C Albensi, Derek R Oliver, Justin Toupin, Gary Oder. Electrical stimulation protocols for hippocampal synaptic plasticity and neuronal hyper-excitability: are they effective or relevant? Experimental neurology. vol 204. issue 1. 2007-05-10. PMID:17258711. |
electrical stimulation protocols for hippocampal synaptic plasticity and neuronal hyper-excitability: are they effective or relevant? |
2007-05-10 |
2023-08-12 |
Not clear |
| Sinthuja Sivagnanasundaram, Danielle Fletcher, Mike Hubank, Elizabeth Illingworth, David Skuse, Peter Scamble. Differential gene expression in the hippocampus of the Df1/+ mice: a model for 22q11.2 deletion syndrome and schizophrenia. Brain research. vol 1139. 2007-05-08. PMID:17292336. |
thus far differential expression of fifteen of these genes involved in signal transduction, synaptic plasticity, neuronal differentiation, microtubule assembly and ubiquitin pathway relevant to hippocampus mediated function have been confirmed by real-time pcr. |
2007-05-08 |
2023-08-12 |
mouse |