| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zacharias Kohl, Nada Ben Abdallah, Jonathan Vogelgsang, Lucas Tischer, Janina Deusser, Davide Amato, Scott Anderson, Christian P Müller, Olaf Riess, Eliezer Masliah, Silke Nuber, Jürgen Winkle. Severely impaired hippocampal neurogenesis associates with an early serotonergic deficit in a BAC α-synuclein transgenic rat model of Parkinson's disease. Neurobiology of disease. vol 85. 2016-09-21. PMID:26523794. |
to characterize the effects of overexpression of human full-length alpha-synuclein on hippocampal cellular and synaptic plasticity, we used a recently generated bac alpha-synuclein transgenic rat model showing important features of pd such as widespread and progressive alpha-synuclein aggregation pathology, dopamine loss and age-dependent motor decline. |
2016-09-21 |
2023-08-13 |
human |
| Hester S Hendriks, Lucas A E Koolen, Milou M L Dingemans, Henrik Viberg, Iwa Lee, Pim E G Leonards, Geert M J Ramakers, Remco H S Westerin. Effects of neonatal exposure to the flame retardant tetrabromobisphenol-A, aluminum diethylphosphinate or zinc stannate on long-term potentiation and synaptic protein levels in mice. Archives of toxicology. vol 89. issue 12. 2016-09-16. PMID:25253649. |
we therefore investigated effects of neonatal exposure to tbbpa, alpi or zs on synaptic plasticity in mouse hippocampus. |
2016-09-16 |
2023-08-13 |
mouse |
| Hester S Hendriks, Lucas A E Koolen, Milou M L Dingemans, Henrik Viberg, Iwa Lee, Pim E G Leonards, Geert M J Ramakers, Remco H S Westerin. Effects of neonatal exposure to the flame retardant tetrabromobisphenol-A, aluminum diethylphosphinate or zinc stannate on long-term potentiation and synaptic protein levels in mice. Archives of toxicology. vol 89. issue 12. 2016-09-16. PMID:25253649. |
on pnd 17-19, effects on hippocampal synaptic plasticity were investigated using ex vivo extracellular field recordings. |
2016-09-16 |
2023-08-13 |
mouse |
| N Zhang, M Xing, Y Wang, H Tao, Y Chen. Repetitive transcranial magnetic stimulation enhances spatial learning and synaptic plasticity via the VEGF and BDNF-NMDAR pathways in a rat model of vascular dementia. Neuroscience. vol 311. 2016-09-14. PMID:26518460. |
spatial learning and memory abilities were evaluated using the morris water maze (mwm), and synaptic plasticity in the hippocampus was assessed via long-term potentiation (ltp). |
2016-09-14 |
2023-08-13 |
rat |
| J-R Hao, N Sun, L Lei, X-Y Li, B Yao, K Sun, R Hu, X Zhang, X-D Shi, C Ga. L-Stepholidine rescues memory deficit and synaptic plasticity in models of Alzheimer's disease via activating dopamine D1 receptor/PKA signaling pathway. Cell death & disease. vol 6. 2016-09-14. PMID:26539912. |
here we investigate the effect and mechanism of l-stepholidine (l-spd), which elicits dopamine d1-type receptor agonistic activity, while acting as d2-type receptor antagonist on cognition and synaptic plasticity in amyloid precursor protein (app) and presenilin 1 (ps1) double-transgenic (app/ps1) mice, and hippocampal cultures or slices treated with addls. |
2016-09-14 |
2023-08-13 |
mouse |
| Huijing Xu, Ahuva Weltman, Min-Chi Hsiao, Kee Scholten, Ellis Meng, Theodore W Berger, Dong Son. Design of a flexible parylene-based multi-electrode array for multi-region recording from the rat hippocampus. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2015. 2016-09-12. PMID:26737938. |
it is also a model structure for the study of cortical function and synaptic plasticity in general because of its special neuro-anatomical structure and intrinsic connections within the hippocampus formation. |
2016-09-12 |
2023-08-13 |
rat |
| Jason K Clark, Matthew Furgerson, Jonathon D Crystal, Marcus Fechheimer, Ruth Furukawa, John J Wagne. Alterations in synaptic plasticity coincide with deficits in spatial working memory in presymptomatic 3xTg-AD mice. Neurobiology of learning and memory. vol 125. 2016-09-09. PMID:26385257. |
field potential recordings from the ca1 region of slices prepared from the ventral hippocampus were obtained to assess synaptic transmission and capability for synaptic plasticity. |
2016-09-09 |
2023-08-13 |
mouse |
| Stefan J Kempf, Sara Sepe, Christine von Toerne, Dirk Janik, Frauke Neff, Stefanie M Hauck, Michael J Atkinson, Pier G Mastroberardino, Soile Tapi. Neonatal Irradiation Leads to Persistent Proteome Alterations Involved in Synaptic Plasticity in the Mouse Hippocampus and Cortex. Journal of proteome research. vol 14. issue 11. 2016-09-09. PMID:26420666. |
neonatal irradiation leads to persistent proteome alterations involved in synaptic plasticity in the mouse hippocampus and cortex. |
2016-09-09 |
2023-08-13 |
mouse |
| Yina Wei, Giri P Krishnan, Maxim Bazheno. Synaptic Mechanisms of Memory Consolidation during Sleep Slow Oscillations. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 15. 2016-09-08. PMID:27076422. |
our study proposes a neuronal mechanism on how an interaction between hippocampal input, such as mediated by sharp wave-ripple events, cortical slow oscillations, and synaptic plasticity, may lead to consolidation of memories through preferential replay of cortical cell spike sequences during slow-wave sleep. |
2016-09-08 |
2023-08-13 |
Not clear |
| Mijeong Park, Chong-Hyun Kim, Seonmi Jo, Eun Joo Kim, Hyewhon Rhim, C Justin Lee, Jeansok J Kim, Jeiwon Ch. Chronic Stress Alters Spatial Representation and Bursting Patterns of Place Cells in Behaving Mice. Scientific reports. vol 5. 2016-09-07. PMID:26548337. |
after administering chronic restraint stress (crs; 6 hours/day for ≥21 consecutive days) to adult male mice, several hippocampal characteristics were examined; i.e., spatial learning, in vitro synaptic plasticity, in vivo place cell recording, and western blot analysis to determine protein levels related to learning and memory. |
2016-09-07 |
2023-08-13 |
mouse |
| Phillip Yang, David Leu, Keqiang Ye, Chandra Srinivasan, John R Fike, Ting-Ting Huan. Cognitive impairments following cranial irradiation can be mitigated by treatment with a tropomyosin receptor kinase B agonist. Experimental neurology. vol 279. 2016-09-06. PMID:26946222. |
this is achieved most likely by preservation of hippocampal neurogenesis and synaptic plasticity. |
2016-09-06 |
2023-08-13 |
mouse |
| Felix Badinter, Tamar Amit, Orit Bar-Am, Moussa B H Youdim, Orly Weinre. Beneficial behavioral, neurochemical and molecular effects of 1-(R)-aminoindan in aged mice. Neuropharmacology. vol 99. 2016-08-30. PMID:26087462. |
in addition, chronic ai treatment significantly enhanced expression levels of neurotrophins, including brain derived neurotrophic factor (bdnf) and nerve growth factor (ngf), tyrosine kinase- b (trk-b) receptor and synaptic plasticity markers, such as synapsin-1 and growth-associated protein-43 (gap-43) in the striatum and hippocampus in aged mice. |
2016-08-30 |
2023-08-13 |
mouse |
| Niels Hansen, Denise Manahan-Vaugha. Hippocampal long-term potentiation that is elicited by perforant path stimulation or that occurs in conjunction with spatial learning is tightly controlled by beta-adrenoreceptors and the locus coeruleus. Hippocampus. vol 25. issue 11. 2016-08-29. PMID:25727388. |
interestingly, the dependency of synaptic plasticity on this receptor is different in the hippocampal subfields whereby in the ca1 in vivo, ltp, but not ltd requires β-adrenoreceptor activation, whereas in the mossy fiber synapse ltp and ltd do not depend on this receptor. |
2016-08-29 |
2023-08-13 |
Not clear |
| Niels Hansen, Denise Manahan-Vaugha. Hippocampal long-term potentiation that is elicited by perforant path stimulation or that occurs in conjunction with spatial learning is tightly controlled by beta-adrenoreceptors and the locus coeruleus. Hippocampus. vol 25. issue 11. 2016-08-29. PMID:25727388. |
by contrast, synaptic plasticity that is facilitated by spatial learning is highly dependent on β-adrenoreceptor activation in both hippocampal subfields. |
2016-08-29 |
2023-08-13 |
Not clear |
| Léa Le Barillier, Lucienne Léger, Pierre-Hervé Luppi, Patrice Fort, Gaël Malleret, Paul-Antoine Sali. Genetic deletion of melanin-concentrating hormone neurons impairs hippocampal short-term synaptic plasticity and hippocampal-dependent forms of short-term memory. Hippocampus. vol 25. issue 11. 2016-08-29. PMID:25808129. |
genetic deletion of melanin-concentrating hormone neurons impairs hippocampal short-term synaptic plasticity and hippocampal-dependent forms of short-term memory. |
2016-08-29 |
2023-08-13 |
mouse |
| Léa Le Barillier, Lucienne Léger, Pierre-Hervé Luppi, Patrice Fort, Gaël Malleret, Paul-Antoine Sali. Genetic deletion of melanin-concentrating hormone neurons impairs hippocampal short-term synaptic plasticity and hippocampal-dependent forms of short-term memory. Hippocampus. vol 25. issue 11. 2016-08-29. PMID:25808129. |
the genetic deletion of the only known mch receptor in rodent leads to an impairment of hippocampal dependent forms of memory and to an alteration of hippocampal long-term synaptic plasticity. |
2016-08-29 |
2023-08-13 |
mouse |
| Léa Le Barillier, Lucienne Léger, Pierre-Hervé Luppi, Patrice Fort, Gaël Malleret, Paul-Antoine Sali. Genetic deletion of melanin-concentrating hormone neurons impairs hippocampal short-term synaptic plasticity and hippocampal-dependent forms of short-term memory. Hippocampus. vol 25. issue 11. 2016-08-29. PMID:25808129. |
by using mch/ataxin3 mice, a genetic model characterized by a selective deletion of mch neurons in the adult, we investigated the role of mch neurons in hippocampal synaptic plasticity and hippocampal-dependent forms of memory. |
2016-08-29 |
2023-08-13 |
mouse |
| Léa Le Barillier, Lucienne Léger, Pierre-Hervé Luppi, Patrice Fort, Gaël Malleret, Paul-Antoine Sali. Genetic deletion of melanin-concentrating hormone neurons impairs hippocampal short-term synaptic plasticity and hippocampal-dependent forms of short-term memory. Hippocampus. vol 25. issue 11. 2016-08-29. PMID:25808129. |
via mch neuron activation, ps could prepare the day's learning by increasing and modulating short-term synaptic plasticity in the hippocampus. |
2016-08-29 |
2023-08-13 |
mouse |
| Mahnaz Bayat, Mohammad Davood Sharifi, Masoud Haghani, Mohammad Shaban. Enriched environment improves synaptic plasticity and cognitive deficiency in chronic cerebral hypoperfused rats. Brain research bulletin. vol 119. issue Pt A. 2016-08-29. PMID:26474515. |
in models of chronic cerebral hypoperfusion, the ability of an ee to restore the cognition depends on hippocampal synaptic plasticity. |
2016-08-29 |
2023-08-13 |
rat |
| Paul A Adlard, Jacqui Parncutt, Varsha Lal, Simon James, Dominic Hare, Philip Doble, David I Finkelstein, Ashley I Bus. Metal chaperones prevent zinc-mediated cognitive decline. Neurobiology of disease. vol 81. 2016-08-22. PMID:25549871. |
while we demonstrated a small regional increase in hippocampal zinc content using synchrotron x-ray fluorescence microscopy, further sub-region analyses are required to determine whether this effect is seen in other regions of the hippocampal formation that are more closely linked to the synaptic plasticity effects observed in this study. |
2016-08-22 |
2023-08-13 |
mouse |