| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Igor Henrique Rodrigues de Paiva, Rodrigo Soares da Silva, Ingrid Prata Mendonça, José Roberto Botelho de Souza, Christina Alves Peixot. Semaglutide Attenuates Anxious and Depressive-Like Behaviors and Reverses the Cognitive Impairment in a Type 2 Diabetes Mellitus Mouse Model Via the Microbiota-Gut-Brain Axis. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 19. issue 1. 2024-07-23. PMID:39042202. |
additionally, semaglutide treatment protected synaptic plasticity and reversed the hippocampal neuroinflammation induced by hfd fed, improving activation of the insulin pathway, demonstrating the protective effects of semaglutide. |
2024-07-23 |
2024-07-25 |
mouse |
| Rongji Hui, Jiabao Xu, Maijie Zhou, Bing Xie, Meiqi Zhou, Ludi Zhang, Bin Cong, Chunling Ma, Di We. Betaine improves METH-induced depressive-like behavior and cognitive impairment by alleviating neuroinflammation via NLRP3 inflammasome inhibotion. Progress in neuro-psychopharmacology & biological psychiatry. 2024-07-19. PMID:39029648. |
moreover, betaine exerted protective effects against meth-induced neural damage and reversed the reduced synaptic plasticity, including the decline in dendritic spine density, as well as alterations in the expression of hippocampal psd95 and synapsin-1. |
2024-07-19 |
2024-07-22 |
mouse |
| Run-Qi Li, Wei-Wen Zhu, Cheng Li, Ke-Bin Zhan, Ping Zhang, Fan Xiao, Jia-Mei Jiang, Wei Zo. Hippocampal Warburg effect Mediates Hydrogen Sulfide-Ameliorated Diabetes-Associated Cognitive Dysfunction: Involving Promotion of Hippocampal Synaptic Plasticity. Neuroscience research. 2024-07-18. PMID:39025266. |
hippocampal warburg effect mediates hydrogen sulfide-ameliorated diabetes-associated cognitive dysfunction: involving promotion of hippocampal synaptic plasticity. |
2024-07-18 |
2024-07-21 |
Not clear |
| Zeying Lu, Lili Gui, Xiaojuan Sun, Ke Wang, Yueheng Lan, Yin Deng, Shiyang Cao, Kun X. Unveiling the impact of low-frequency electrical stimulation on network synchronization and learning behavior in cultured hippocampal neural networks. Biochemical and biophysical research communications. vol 731. 2024-07-17. PMID:39018969. |
these alterations in network properties indicated enhanced synaptic plasticity and emphasized the positive impact of low-frequency es on hippocampal neural activities, contributing to the brain's capacity for learning and memory. |
2024-07-17 |
2024-07-20 |
Not clear |
| Giota Tsotsokou, Athina Miliou, George Trompoukis, Leonidas J Leontiadis, Costas Papatheodoropoulo. Region-Related Differences in Short-Term Synaptic Plasticity and Synaptotagmin-7 in the Male and Female Hippocampus of a Rat Model of Fragile X Syndrome. International journal of molecular sciences. vol 25. issue 13. 2024-07-13. PMID:39000085. |
region-related differences in short-term synaptic plasticity and synaptotagmin-7 in the male and female hippocampus of a rat model of fragile x syndrome. |
2024-07-13 |
2024-07-15 |
rat |
| Chunxiao Tian, Yenan Qi, Yu Zheng, Pei Xia, Qiwen Liu, Mengying Luan, Junyao Zheng, Rujuan Song, Meng Wang, Dejiao Qi, Chan Xiong, Lei Don. Exploring the Effect of Arsenic-Containing Hydrocarbon on the Bidirectional Synaptic Plasticity of the Dorsal Hippocampus. International journal of molecular sciences. vol 25. issue 13. 2024-07-13. PMID:39000331. |
exploring the effect of arsenic-containing hydrocarbon on the bidirectional synaptic plasticity of the dorsal hippocampus. |
2024-07-13 |
2024-07-15 |
Not clear |
| Elena D Bagatelas, Ege T Kavalal. Chronic modulation of cAMP signaling elicits synaptic scaling irrespective of activity. iScience. vol 27. issue 7. 2024-07-11. PMID:38989459. |
here, we employed a chemogenetic approach to regulate activity via eliciting g protein-coupled receptor (gpcr) signaling in hippocampal neurons to trigger homeostatic synaptic plasticity. |
2024-07-11 |
2024-07-13 |
Not clear |
| Melih Tarhan, Tim Hartl, Olena Shchyglo, Jens Colitti-Klausnitzer, Angela Kuhla, Tobias Maximilian Breuer, Denise Manahan-Vaugha. Changes in hippocampal volume, synaptic plasticity and amylin sensitivity in an animal model of type 2 diabetes are associated with increased vulnerability to amyloid-beta in advancing age. Frontiers in aging neuroscience. vol 16. 2024-07-08. PMID:38974903. |
changes in hippocampal volume, synaptic plasticity and amylin sensitivity in an animal model of type 2 diabetes are associated with increased vulnerability to amyloid-beta in advancing age. |
2024-07-08 |
2024-07-11 |
Not clear |
| Naif H Ali, Hayder M Al-Kuraishy, Ali I Al-Gareeb, Najah R Hadi, Abdullah A Assiri, Mohammed Alrouji, Nermeen N Welson, Athanasios Alexiou, Marios Papadakis, Gaber El-Saber Batih. Hypoglycemia and Alzheimer Disease Risk: The Possible Role of Dasiglucagon. Cellular and molecular neurobiology. vol 44. issue 1. 2024-07-08. PMID:38977507. |
glucagon/glp-1 has been shown to promote synaptogenesis, hippocampal synaptic plasticity, and learning and memory, while attenuating amyloid and tau pathologies. |
2024-07-08 |
2024-07-12 |
Not clear |
| Roland Tresky, Yuta Miyamoto, Yu Nagayoshi, Yasushi Yabuki, Kimi Araki, Yukie Takahashi, Yoshihiro Komohara, Huicong Ge, Kayo Nishiguchi, Takaichi Fukuda, Hitomi Kaneko, Nobuko Maeda, Jin Matsuura, Shintaro Iwasaki, Kourin Sakakida, Norifumi Shioda, Fan-Yan Wei, Kazuhito Tomizawa, Takeshi Chuj. TRMT10A dysfunction perturbs codon translation of initiator methionine and glutamine and impairs brain functions in mice. Nucleic acids research. 2024-07-01. PMID:38950903. |
despite not showing discernable defects in the pancreas, liver, or kidney, trmt10a null mice showed lower body weight and smaller hippocampal postsynaptic densities, which is associated with defective synaptic plasticity and memory. |
2024-07-01 |
2024-07-04 |
mouse |
| Ga-Young Choi, In-Seo Lee, Eunyoung Moon, Hyosung Choi, A Reum Je, Ji-Ho Park, Hee-Seok Kweo. Ameliorative effect of vanillic acid against scopolamine-induced learning and memory impairment in rat via attenuation of oxidative stress and dysfunctional synaptic plasticity. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 177. 2024-06-28. PMID:38941895. |
additionally, the measurement of long-term potentiation was used to determine the function of synaptic plasticity in organotypic hippocampal slice cultures. |
2024-06-28 |
2024-07-01 |
rat |
| Ga-Young Choi, In-Seo Lee, Eunyoung Moon, Hyosung Choi, A Reum Je, Ji-Ho Park, Hee-Seok Kweo. Ameliorative effect of vanillic acid against scopolamine-induced learning and memory impairment in rat via attenuation of oxidative stress and dysfunctional synaptic plasticity. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 177. 2024-06-28. PMID:38941895. |
the study's findings suggest that va has a neuroprotective effect on scop-induced learning and memory impairment linked to the hippocampal cholinergic system, oxidative damage, and synaptic plasticity. |
2024-06-28 |
2024-07-01 |
rat |
| Norman Holl, Marco Heerdegen, Volker Zschorlich, Rüdiger Köhling, Timo Kirschstei. Inhibition of Acute mGluR5-Dependent Depression in Hippocampal CA1 by High-Frequency Magnetic Stimulation. Brain sciences. vol 14. issue 6. 2024-06-27. PMID:38928603. |
high-frequency magnetic stimulation (hfms) applied directly to the hippocampal slice preparation in vitro induces activity-dependent synaptic plasticity and metaplasticity. |
2024-06-27 |
2024-06-29 |
Not clear |
| Emilija Glavonic, Milorad Dragic, Milos Mitic, Minja Aleksic, Iva Lukic, Sanja Ivkovic, Miroslav Adzi. Ketamine's Amelioration of Fear Extinction in Adolescent Male Mice Is Associated with the Activation of the Hippocampal Akt-mTOR-GluA1 Pathway. Pharmaceuticals (Basel, Switzerland). vol 17. issue 6. 2024-06-27. PMID:38931336. |
we analyzed the protein and gene expression of synaptic plasticity markers in the hippocampus (hpc) and prefrontal cortex (pfc) and sought to identify neural correlates associated with ketamine's effects on adolescent extinction learning. |
2024-06-27 |
2024-06-29 |
mouse |
| Felipe C Ribeiro, Danielle Cozachenco, Elentina K Argyrousi, Agnieszka Staniszewski, Shane Wiebe, Joao D Calixtro, Rubens Soares-Neto, Aycheh Al-Chami, Fatema El Sayegh, Sara Bermudez, Emily Arsenault, Marcelo Cossenza, Jean-Claude Lacaille, Karim Nader, Hongyu Sun, Fernanda G De Felice, Mychael V Lourenco, Ottavio Arancio, Argel Aguilar-Valles, Nahum Sonenberg, Sergio T Ferreir. The ketamine metabolite (2R,6R)-hydroxynorketamine rescues hippocampal mRNA translation, synaptic plasticity and memory in mouse models of Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024-06-27. PMID:38934107. |
the ketamine metabolite (2r,6r)-hydroxynorketamine rescues hippocampal mrna translation, synaptic plasticity and memory in mouse models of alzheimer's disease. |
2024-06-27 |
2024-06-29 |
mouse |
| Baoyue Zhang, Jun Zhao, Caiqin Yan, Yiming Bai, Pengfei Guo, Chao Wang, Zhe Wang, Guanhua Du, Ailin Li. Combination of RNA-seq and proteomics reveals the mechanism of DL0410 treatment in APP/PS1 transgenic mouse model of Alzheimer's disease. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 177. 2024-06-26. PMID:38925020. |
dl0410 significantly reduced β-amyloid deposition and resulted in significant upregulation of synaptophysin, psd95 and nmdar/ camkⅡ signaling pathway in the hippocampus and cortex, indicating that dl0410 improved synaptic plasticity in app/ps1 mice, which agrees with the results of rna-seq and proteomics. |
2024-06-26 |
2024-06-29 |
mouse |
| Kevin D Phelan, U Thaung Shwe, Hong Wu, Fang Zhen. Investigating Contributions of Canonical Transient Receptor Potential Channel 3 to Hippocampal Hyperexcitability and Seizure-Induced Neuronal Cell Death. International journal of molecular sciences. vol 25. issue 11. 2024-06-19. PMID:38892448. |
in this study, we investigated the contribution of trpc3 channels to the electrophysiological properties of hippocampal pyramidal neurons and hippocampal synaptic plasticity, and the contribution of trpc3 channels to seizure-induced neuronal cell death. |
2024-06-19 |
2024-06-21 |
Not clear |
| Kyung-Jun Boo, Dae Hyun Kim, Eunbi Cho, Dong Hyun Kim, Se Jin Jeon, Chan Young Shi. Neonatal dysregulation of 2-arachidonoylglycerol induces impaired brain function in adult mice. Neuropharmacology. 2024-06-17. PMID:38885736. |
do34-injected mice showed significantly decreased cognitive functions, attributed to impairment of hippocampal synaptic plasticity. |
2024-06-17 |
2024-06-21 |
mouse |
| Jun Zhu, Yueru Hou, Wan Li, Xin Wang, Fei Li, Nan Li, Yan Hu, Xuelian Wang, Shun-Nan G. miR-181a Expressed in the Dorsal Hippocampus Regulates the Reinstatement of Cocaine CPP by Targeting PRKAA1. Behavioural brain research. 2024-06-15. PMID:38878971. |
mir-181a, which is widely expressed in the hippocampus, acts as a regulator for synaptic plasticity, while its role in drug reinstatement is unclear. |
2024-06-15 |
2024-06-18 |
Not clear |
| Guilherme Shigueto Vilar Higa, Felipe José Costa Viana, José Francis-Oliveira, Emily Cruvinel, Thainá Soares Franchin, Tania Marcourakis, Henning Ulrich, Roberto De Pasqual. Serotonergic Neuromodulation of Synaptic Plasticity. Neuropharmacology. 2024-06-14. PMID:38876308. |
through a comparative analysis across three main forebrain structures-the hippocampus, amygdala, and prefrontal cortex, this review discusses the actions of 5-ht on synaptic plasticity, offering insights into its role as a neuromodulator involved in emotional and cognitive functions. |
2024-06-14 |
2024-06-17 |
Not clear |