| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Diogo Bessa-Neto, Daniel Choque. Molecular mechanisms of AMPAR reversible stabilization at synapses. Molecular and cellular neurosciences. 2023-04-27. PMID:37105372. |
these partial immobilizations and localization of glutamatergic receptors within the synaptic sites are fundamental for proper basal transmission and synaptic plasticity. |
2023-04-27 |
2023-08-14 |
Not clear |
| Elena Ferrari, Michela Salvadè, Elisa Zianni, Marta Brumana, Monica DiLuca, Fabrizio Gardon. Detrimental effects of soluble α-synuclein oligomers at excitatory glutamatergic synapses. Frontiers in aging neuroscience. vol 15. 2023-04-03. PMID:37009450. |
of note, soluble oligomers have recently been shown to alter synaptic plasticity mechanisms at the glutamatergic cortico-striatal synapse. |
2023-04-03 |
2023-08-14 |
Not clear |
| Pratik Chakraborty, Abhijit Dey, Abilash Valsala Gopalakrishnan, Kumari Swati, Shreesh Ojha, Anand Prakash, Dhruv Kumar, Rashmi K Ambasta, Niraj Kumar Jha, Saikat Dewanjee, Saurabh Kumar Jh. Glutamatergic Neurotransmission: A Potential Pharmacotherapeutic Target for the Treatment of Cognitive Disorders. Ageing research reviews. 2023-01-07. PMID:36610558. |
cognitive activities are potentially synchronized by the glutamatergic activities in the brain via restoring synaptic plasticity. |
2023-01-07 |
2023-08-14 |
Not clear |
| Pratik Chakraborty, Abhijit Dey, Abilash Valsala Gopalakrishnan, Kumari Swati, Shreesh Ojha, Anand Prakash, Dhruv Kumar, Rashmi K Ambasta, Niraj Kumar Jha, Saikat Dewanjee, Saurabh Kumar Jh. Glutamatergic Neurotransmission: A Potential Pharmacotherapeutic Target for the Treatment of Cognitive Disorders. Ageing research reviews. 2023-01-07. PMID:36610558. |
dysfunctional glutamate receptors and other glutamatergic components are responsible for the aberrant glutamatergic activity in the brain that cause cognitive impairments, loss of synaptic plasticity, and neuronal damage. |
2023-01-07 |
2023-08-14 |
Not clear |
| Halley R Washburn, Praveen Chander, Kolluru D Srikanth, Matthew B Dalv. Transsynaptic Signaling of Ephs in Synaptic Development, Plasticity, and Disease. Neuroscience. 2022-12-02. PMID:36460219. |
of these families, the ephbs and ephrin-bs are required during each phase of synaptic development from target selection, recruitment of synaptic proteins, and formation of spines to regulation of synaptic plasticity at glutamatergic spine synapses in the mature brain. |
2022-12-02 |
2023-08-14 |
human |
| Marios C Panayi, Thomas Boerner, Thomas Jahans-Price, Anna Huber, Rolf Sprengel, Gary Gilmour, David J Sanderson, Paul J Harrison, Mark E Walton, David M Bannerma. Glutamatergic dysfunction leads to a hyper-dopaminergic phenotype through deficits in short-term habituation: a mechanism for aberrant salience. Molecular psychiatry. 2022-12-02. PMID:36460723. |
various lines of evidence point to glutamatergic dysfunction and impairments in synaptic plasticity in the etiology of schizophrenia, including deficits associated with the glua1 ampar subunit. |
2022-12-02 |
2023-08-14 |
Not clear |
| Carolina Flores-Muñoz, Francisca García-Rojas, Miguel A Pérez, Odra Santander, Elena Mery, Stefany Ordenes, Javiera Illanes-González, Daniela López-Espíndola, Arlek M González-Jamett, Marco Fuenzalida, Agustín D Martínez, Álvaro O Ardile. The Long-Term Pannexin 1 Ablation Produces Structural and Functional Modifications in Hippocampal Neurons. Cells. vol 11. issue 22. 2022-11-26. PMID:36429074. |
the panx1 channel ablation alters the hippocampus's glutamatergic neurotransmission, synaptic plasticity, and memory flexibility. |
2022-11-26 |
2023-08-14 |
mouse |
| Elisabetta Gerace, Lorenzo Polenzani, Maurizio Magnani, Elisa Zianni, Gabriella Stocca, Fabrizio Gardoni, Domenico E Pellegrini-Giampietro, Renato Corradett. Antidepressant-induced increase in GluA2 expression does not translate in changes of AMPA receptor-mediated synaptic transmission at CA3/CA1 synapses in rats. Neuropharmacology. 2022-11-05. PMID:36334766. |
these changes in ampar composition have been suggested to result in increased glutamatergic neurotransmission and possibly underlie enhanced hippocampal synaptic plasticity through the increased availability of calcium-permeable ampars, specifically at ca3/ca1 synapses. |
2022-11-05 |
2023-08-14 |
rat |
| Siqi Wang, Lihua Bian, Yi Yin, Jianyou Gu. Targeting NMDA Receptors in Emotional Disorders: Their Role in Neuroprotection. Brain sciences. vol 12. issue 10. 2022-10-27. PMID:36291261. |
excitatory glutamatergic neurotransmission mediated through n-methyl-d-aspartate (nmda) receptors (nmdars) is essential for synaptic plasticity and neuronal survival. |
2022-10-27 |
2023-08-14 |
Not clear |
| Mohamad Azmeer Effendy, Suleiman Yunusa, Noorul Hamizah Mat, Ahmad Tarmizi Che Has, Christian P Müller, Zurina Hassa. The role of AMPA and NMDA receptors in mitragynine effects on hippocampal synaptic plasticity. Behavioural brain research. 2022-10-23. PMID:36273648. |
however, the role of glutamatergic neurotransmission modulating synaptic plasticity in mitragynine-induced synaptic changes is still unknown. |
2022-10-23 |
2023-08-14 |
rat |
| Chuan-Hsiu Liu, Mei-Ying Chen, Jack Cheng, Tsai-Ni Chuang, Hsin-Ping Liu, Wei-Yong Li. Imidacloprid Impairs Glutamatergic Synaptic Plasticity and Desensitizes Mechanosensitive, Nociceptive, and Photogenic Response of International journal of molecular sciences. vol 23. issue 17. 2022-09-09. PMID:36077576. |
imidacloprid impairs glutamatergic synaptic plasticity and desensitizes mechanosensitive, nociceptive, and photogenic response of imidacloprid (imd) is a widely used neonicotinoid-targeting insect nicotine acetylcholine receptors (nachrs). |
2022-09-09 |
2023-08-14 |
drosophila_melanogaster |
| Anand Gururaja. The impact of chronic stress on the PFC transcriptome: a bioinformatic meta-analysis of publicly available RNA-sequencing datasets. Stress (Amsterdam, Netherlands). vol 25. issue 1. 2022-08-19. PMID:35983587. |
the results showed 160 differentially expressed genes in chronic stress mice compared to controls with significant enrichment in mechanisms associated with translation and localization of membrane-bound proteins with a putative effect on synaptic plasticity in glutamatergic neurons. |
2022-08-19 |
2023-08-14 |
mouse |
| Caitlyn A Chapman, Jessica L Nuwer, Tija C Jaco. The Yin and Yang of GABAergic and Glutamatergic Synaptic Plasticity: Opposites in Balance by Crosstalking Mechanisms. Frontiers in synaptic neuroscience. vol 14. 2022-06-06. PMID:35663370. |
the yin and yang of gabaergic and glutamatergic synaptic plasticity: opposites in balance by crosstalking mechanisms. |
2022-06-06 |
2023-08-14 |
Not clear |
| Lian Liu, Luqi Dai, Dan Xu, Yinchan Wang, Lin Bai, Xiaoting Chen, Mengzhou Li, Shuai Yang, Yuying Tan. Astrocyte secreted IL-6 to modulate PSD-95 palmitoylation in basolateral amygdala and depression-like behaviors induced by peripheral nerve injury. Brain, behavior, and immunity. 2022-05-31. PMID:35636613. |
dysfunction of glutamatergic synaptic plasticity in basolateral amygdala (bla) constitutes a critical pathogenic mechanism underlying the depression-like behaviors induced by chronic pain. |
2022-05-31 |
2023-08-13 |
Not clear |
| Zu-Cheng Shen, Zhi-Xuan Xia, Jian-Min Liu, Jie-Yan Zheng, Yu-Fei Luo, Han Yang, Meng-Die Li, Ting Cao, Hai-Ping Liu, Gui-Lin Jin, Hui-Hui Huang, Chang-Xi Yu, Jun Zho. APT1-mediated de-palmitoylation regulates hippocampal synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-02-15. PMID:35165175. |
herein, we employed acyl-biotin exchange, co-immunoprecipitation and biotinylation assays, and behavioral and electrophysiological methods, to explore whether palmitoylation is required for hippocampal synaptic transmission and fear memory formation, and involved in functional modification of synaptic proteins such as psd-95 and glutamate receptors, and detected if de-palmitoylation by specific enzymes has influence on glutamatergic synaptic plasticity. |
2022-02-15 |
2023-08-13 |
rat |
| Zu-Cheng Shen, Zhi-Xuan Xia, Jian-Min Liu, Jie-Yan Zheng, Yu-Fei Luo, Han Yang, Meng-Die Li, Ting Cao, Hai-Ping Liu, Gui-Lin Jin, Hui-Hui Huang, Chang-Xi Yu, Jun Zho. APT1-mediated de-palmitoylation regulates hippocampal synaptic plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-02-15. PMID:35165175. |
these results suggest that palmitoylation and apt1-mediated de-palmitoylation have critical effects on the regulation of glutamatergic synaptic plasticity, and it may serve as a potential target for learning and memory-associated disorders. |
2022-02-15 |
2023-08-13 |
rat |
| Tiziana Ravasenga, Massimo Ruben, Vincenzo Regio, Alice Polenghi, Enrica Maria Petrini, Andrea Barberi. Spatial regulation of coordinated excitatory and inhibitory synaptic plasticity at dendritic synapses. Cell reports. vol 38. issue 6. 2022-02-09. PMID:35139381. |
the induction of synaptic plasticity at an individual dendritic glutamatergic spine can affect neighboring spines. |
2022-02-09 |
2023-08-13 |
Not clear |
| Joyce Keife. Regulation of AMPAR trafficking in synaptic plasticity by BDNF and the impact of neurodegenerative disease. Journal of neuroscience research. 2022-02-07. PMID:35128708. |
research demonstrates that the neural mechanisms underlying synaptic plasticity and learning and memory involve mobilization of ampa-type neurotransmitter receptors at glutamatergic synaptic contacts, and that these mechanisms are targeted during neurodegenerative disease. |
2022-02-07 |
2023-08-13 |
Not clear |
| Shanyan Chen, Heather R Siedhoff, Hua Zhang, Pei Liu, Ashley Balderrama, Runting Li, Catherine Johnson, C Michael Greenlief, Bastijn Koopmans, Timothy Hoffman, Ralph G DePalma, De-Pei Li, Jiankun Cui, Zezong G. Low-intensity blast induces acute glutamatergic hyperexcitability in mouse hippocampus leading to long-term learning deficits and altered expression of proteins involved in synaptic plasticity and serine protease inhibitors. Neurobiology of disease. 2022-01-25. PMID:35077822. |
low-intensity blast induces acute glutamatergic hyperexcitability in mouse hippocampus leading to long-term learning deficits and altered expression of proteins involved in synaptic plasticity and serine protease inhibitors. |
2022-01-25 |
2023-08-13 |
mouse |
| Li-Min Mao, Alaya Bodepudi, Xiang-Ping Chu, John Q Wan. Group I Metabotropic Glutamate Receptors and Interacting Partners: An Update. International journal of molecular sciences. vol 23. issue 2. 2022-01-21. PMID:35055030. |
these receptors play key roles in the modulation of normal glutamatergic transmission and synaptic plasticity, and abnormal mglu1/5 signaling is linked to the pathogenesis and symptomatology of various mental and neurological disorders. |
2022-01-21 |
2023-08-13 |
Not clear |