| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Seena S Mathew, John J Hablit. Presynaptic NMDA receptors mediate IPSC potentiation at GABAergic synapses in developing rat neocortex. PloS one. vol 6. issue 2. 2011-09-01. PMID:21365001. |
physiological studies of presynaptic nmda receptors on neocortical gabaergic terminals and their possible role in synaptic plasticity are lacking. |
2011-09-01 |
2023-08-12 |
rat |
| Lucas Matt, Stylianos Michalakis, Franz Hofmann, Verena Hammelmann, Andreas Ludwig, Martin Biel, Thomas Kleppisc. HCN2 channels in local inhibitory interneurons constrain LTP in the hippocampal direct perforant path. Cellular and molecular life sciences : CMLS. vol 68. issue 1. 2011-02-11. PMID:20623157. |
we conclude that hcn2 channels in inhibitory interneurons modulate synaptic plasticity in the pp by facilitating the gabaergic output onto pyramidal neurons. |
2011-02-11 |
2023-08-12 |
mouse |
| Shiva K Tyagarajan, Himanish Ghosh, Gonzalo E Yévenes, Irina Nikonenko, Claire Ebeling, Cornelia Schwerdel, Corinne Sidler, Hanns Ulrich Zeilhofer, Bertran Gerrits, Dominique Muller, Jean-Marc Fritsch. Regulation of GABAergic synapse formation and plasticity by GSK3beta-dependent phosphorylation of gephyrin. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 1. 2011-02-10. PMID:21173228. |
together, these findings identify gephyrin as synaptogenic molecule regulating gabaergic synaptic plasticity, likely contributing to the therapeutic action of lithium. |
2011-02-10 |
2023-08-12 |
Not clear |
| Andrés Buonann. The neuregulin signaling pathway and schizophrenia: from genes to synapses and neural circuits. Brain research bulletin. vol 83. issue 3-4. 2011-01-06. PMID:20688137. |
next, the review focuses on the possible significance of genetic studies associating nrg1 and erbb4 with schizophrenia, in light of the functional role of this signaling pathway in regulating glutamatergic, gabaergic and dopaminergic neurotransmission, as well as modulating synaptic plasticity and gamma oscillations. |
2011-01-06 |
2023-08-12 |
Not clear |
| Toshihiko Aosaki, Masami Miura, Takeo Suzuki, Kinya Nishimura, Masao Masud. Acetylcholine-dopamine balance hypothesis in the striatum: an update. Geriatrics & gerontology international. vol 10 Suppl 1. 2010-10-21. PMID:20590830. |
the pause response begins with dopamine d5 receptor-dependent synaptic plasticity in the cholinergic neurons and an increased gabaergic ipsp, which is followed by a long pause in firing through d2 and d5 receptor-dependent modulation of ion channels. |
2010-10-21 |
2023-08-12 |
Not clear |
| Hui Lu, Pei-Lin Cheng, Byung Kook Lim, Nina Khoshnevisrad, Mu-Ming Po. Elevated BDNF after cocaine withdrawal facilitates LTP in medial prefrontal cortex by suppressing GABA inhibition. Neuron. vol 67. issue 5. 2010-10-01. PMID:20826313. |
this enhanced synaptic plasticity could be attributed to bdnf-induced suppression of gabaergic inhibition in the mpfc by reducing the surface expression of gaba(a) receptors. |
2010-10-01 |
2023-08-12 |
rat |
| C Papatheodoropoulo. Patterned activation of hippocampal network (approximately 10 Hz) during in vitro sharp wave-ripples. Neuroscience. vol 168. issue 2. 2010-08-19. PMID:20371272. |
we propose that sequential approximately 10 hz clustered activation of the local hippocampal circuit occurring under the dynamics of spws and depending on nmda receptors and an accurate level of gabaergic synaptic transmission is an essential pattern of precisely controlled network activity involved in synaptic plasticity processes with potential implications in mnemonic functions. |
2010-08-19 |
2023-08-12 |
rat |
| Wiebke Nissen, Andras Szabo, Jozsef Somogyi, Peter Somogyi, Karri P Lams. Cell type-specific long-term plasticity at glutamatergic synapses onto hippocampal interneurons expressing either parvalbumin or CB1 cannabinoid receptor. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 4. 2010-07-08. PMID:20107060. |
we show that long-term potentiation (ltp) and depression (ltd), two common forms of synaptic plasticity, are expressed in a highly cell type-specific manner at glutamatergic synapses onto hippocampal gabaergic neurons. |
2010-07-08 |
2023-08-12 |
Not clear |
| Loren J Martin, Agnieszka A Zurek, John F MacDonald, John C Roder, Michael F Jackson, Beverley A Orse. Alpha5GABAA receptor activity sets the threshold for long-term potentiation and constrains hippocampus-dependent memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 15. 2010-05-14. PMID:20392949. |
the prevailing notion is that a synaptic or phasic form of gabaergic inhibition regulates synaptic plasticity; however, little is known about the role of gaba(a)r subtypes that generate a tonic or persistent inhibitory conductance. |
2010-05-14 |
2023-08-12 |
mouse |
| Shiva K Tyagarajan, Jean-Marc Fritsch. GABA(A) receptors, gephyrin and homeostatic synaptic plasticity. The Journal of physiology. vol 588. issue Pt 1. 2010-03-25. PMID:19752109. |
therefore, we postulate that homeostatic synaptic plasticity depends on signalling cascades regulating in parallel the efficacy of glutamatergic and gabaergic transmission. |
2010-03-25 |
2023-08-12 |
Not clear |
| Marco Rohde, Tursonjan Tokay, Rüdiger Köhling, Timo Kirschstei. GABA(A) receptor inhibition does not affect mGluR-dependent LTD at hippocampal Schaffer collateral-CA1 synapses. Neuroscience letters. vol 467. issue 1. 2010-02-25. PMID:19800390. |
inhibitory gabaergic interneurons in this region abundantly terminate on pyramidal neurons and may thus influence synaptic plasticity. |
2010-02-25 |
2023-08-12 |
rat |
| Huan-Xin Chen, Mali Jiang, Dilek Akakin, Steven N Rope. Long-term potentiation of excitatory synapses on neocortical somatostatin-expressing interneurons. Journal of neurophysiology. vol 102. issue 6. 2010-02-22. PMID:19776361. |
synaptic plasticity has been extensively studied in principal neurons of the neocortex, but less work has been done on gabaergic interneurons. |
2010-02-22 |
2023-08-12 |
mouse |
| P J West, V R Marcy, M J Marino, H Schaffhause. Activation of the 5-HT(6) receptor attenuates long-term potentiation and facilitates GABAergic neurotransmission in rat hippocampus. Neuroscience. vol 164. issue 2. 2010-02-12. PMID:19660530. |
taken together, these results suggest that the 5-ht(6) receptor plays a role in the modulation of synaptic plasticity in hippocampal area ca1 and that the regulation of gabaergic interneuron activity may underlie the cognition enhancing effects of 5-ht(6) antagonists. |
2010-02-12 |
2023-08-12 |
rat |
| Neng Gong, Yong Li, Guo-Qiang Cai, Rui-Fang Niu, Qi Fang, Kun Wu, Zhong Chen, Long-Nian Lin, Lin Xu, Jian Fei, Tian-Le X. GABA transporter-1 activity modulates hippocampal theta oscillation and theta burst stimulation-induced long-term potentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 50. 2010-01-26. PMID:20016099. |
the network oscillation and synaptic plasticity are known to be regulated by gabaergic inhibition, but how they are affected by changes in the gaba transporter activity remains unclear. |
2010-01-26 |
2023-08-12 |
mouse |
| Neng Gong, Yong Li, Guo-Qiang Cai, Rui-Fang Niu, Qi Fang, Kun Wu, Zhong Chen, Long-Nian Lin, Lin Xu, Jian Fei, Tian-Le X. GABA transporter-1 activity modulates hippocampal theta oscillation and theta burst stimulation-induced long-term potentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 50. 2010-01-26. PMID:20016099. |
together, these results have highlighted the important link between gabaergic inhibition and hippocampal theta oscillation, both of which are critical for synaptic plasticity and learning behaviors. |
2010-01-26 |
2023-08-12 |
mouse |
| Richard S Saliba, Zhenglin Gu, Zhen Yan, Stephen J Mos. Blocking L-type voltage-gated Ca2+ channels with dihydropyridines reduces gamma-aminobutyric acid type A receptor expression and synaptic inhibition. The Journal of biological chemistry. vol 284. issue 47. 2009-12-14. PMID:19778903. |
chronic changes in neuronal activity lead to an adaptive modulation in the efficacy of gabaergic synaptic inhibition, brought about in part by changes in the number of synaptic gaba(a)rs, a mechanism known as homeostatic synaptic plasticity. |
2009-12-14 |
2023-08-12 |
Not clear |
| Alexander Dityatev, Olena Bukalo, Melitta Schachne. Modulation of synaptic transmission and plasticity by cell adhesion and repulsion molecules. Neuron glia biology. vol 4. issue 3. 2009-11-16. PMID:19674506. |
the emerging mechanisms by which adhesive ig-cams contribute to synaptic plasticity involve regulation of activities of nmda receptors and l-type ca2+ channels, signaling via mitogen-activated protein kinase p38, changes in gabaergic inhibition and motility of synaptic elements. |
2009-11-16 |
2023-08-12 |
mouse |
| Lei Niu, Bing Cao, Hong Zhu, Bin Mei, Ming Wang, Yupeng Yang, Yifeng Zho. Impaired in vivo synaptic plasticity in dentate gyrus and spatial memory in juvenile rats induced by prenatal morphine exposure. Hippocampus. vol 19. issue 7. 2009-08-31. PMID:19115391. |
taken together, our results suggest that prenatal morphine exposure impairs the juvenile offspring's dentate synaptic plasticity and spatial memory, and that decreased gabaergic inhibition may play a role in these effects. |
2009-08-31 |
2023-08-12 |
rat |
| Peter Jedlicka, Theofilos Papadopoulos, Thomas Deller, Heinrich Betz, Stephan W Schwarzache. Increased network excitability and impaired induction of long-term potentiation in the dentate gyrus of collybistin-deficient mice in vivo. Molecular and cellular neurosciences. vol 41. issue 1. 2009-06-01. PMID:19236916. |
in conclusion, our data provide the first evidence that cb-deficiency leads to significant changes of gabaergic inhibition, network excitability and synaptic plasticity in vivo. |
2009-06-01 |
2023-08-12 |
mouse |
| Katrin Hoffmann, Elena Sivukhina, Heidrun Potschka, Melitta Schachner, Wolfgang Löscher, Alexander Dityate. Retarded kindling progression in mice deficient in the extracellular matrix glycoprotein tenascin-R. Epilepsia. vol 50. issue 4. 2009-05-12. PMID:19178559. |
the idea that tnr may be important for this process was suggested by previous studies showing that deficiency in tnr leads to abnormalities in synaptic plasticity, perisomatic gabaergic inhibition and more astrocytes in the hippocampus of adult mice. |
2009-05-12 |
2023-08-12 |
mouse |