| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Masoumeh Nazari, Alireza Komaki, Ruhollah Karamian, Siamak Shahidi, Abdolrahman Sarihi, Masoumeh Asadbeg. The interactive role of CB(1) and GABA(B) receptors in hippocampal synaptic plasticity in rats. Brain research bulletin. vol 120. 2016-09-30. PMID:26611204. |
changes in gabaergic inhibition have also been shown to affect synaptic plasticity in the hippocampus. |
2016-09-30 |
2023-08-13 |
rat |
| Natasja M W J de Bruin, Chris G Krus. 5-HT6 Receptor Antagonists: Potential Efficacy for the Treatment of Cognitive Impairment in Schizophrenia. Current pharmaceutical design. vol 21. issue 26. 2016-06-03. PMID:26044973. |
5-ht6r antagonists decrease gaba release and gabaergic interneuron excitability, which subsequently disinhibits glutamate and/or acetylcholine release and results in enhancement of synaptic plasticity. |
2016-06-03 |
2023-08-13 |
Not clear |
| Tomi Rantamäki, Ipek Yalci. Antidepressant drug action--From rapid changes on network function to network rewiring. Progress in neuro-psychopharmacology & biological psychiatry. vol 64. 2016-05-31. PMID:26066070. |
the delayed-onset of action of monoamine-based antidepressant drugs have been associated to their ability to slowly increase synaptic plasticity and neuronal excitability via altering neurotrophic signaling (synthesis of bdnf and activation of its receptor trkb), dematuration of gabaergic interneurons and inhibition of "breaks of plasticity". |
2016-05-31 |
2023-08-13 |
Not clear |
| Yoko Hanno-Iijima, Masami Tanaka, Takatoshi Iijim. Activity-Dependent Bidirectional Regulation of GAD Expression in a Homeostatic Fashion Is Mediated by BDNF-Dependent and Independent Pathways. PloS one. vol 10. issue 8. 2016-05-17. PMID:26241953. |
however, gene regulation that underlies homeostatic synaptic plasticity in gabaergic (gaba, gamma aminobutyric) neurons is still poorly understood. |
2016-05-17 |
2023-08-13 |
Not clear |
| Hajime Abe, Fumiyo Saito, Takeshi Tanaka, Sayaka Mizukami, Yasuko Hasegawa-Baba, Nobuya Imatanaka, Yumi Akahori, Toshinori Yoshida, Makoto Shibutan. Developmental cuprizone exposure impairs oligodendrocyte lineages differentially in cortical and white matter tissues and suppresses glutamatergic neurogenesis signals and synaptic plasticity in the hippocampal dentate gyrus of rats. Toxicology and applied pharmacology. vol 290. 2016-05-10. PMID:26577399. |
cpz also reversibly targeted glutamatergic signals of gabaergic interneuron to affect dentate gyrus neurogenesis and synaptic plasticity in granule cells. |
2016-05-10 |
2023-08-13 |
rat |
| Elizabeth Nieto Mendoza, Elizabeth Hernández Echeagara. Dopaminergic Modulation of Striatal Inhibitory Transmission and Long-Term Plasticity. Neural plasticity. vol 2015. 2016-04-19. PMID:26294980. |
this work focused on the analysis of both dopaminergic modulation of inhibitory synapses and the synaptic plasticity established between gabaergic afferents to medium spiny neurons (msns). |
2016-04-19 |
2023-08-13 |
Not clear |
| Alessandro Guidotti, Dennis R Grayson, Hector J Carunch. Epigenetic RELN Dysfunction in Schizophrenia and Related Neuropsychiatric Disorders. Frontiers in cellular neuroscience. vol 10. 2016-04-19. PMID:27092053. |
the decreased synthesis and release of reln from gabaergic corticolimbic neurons could serve as a model to elucidate the epigenetic pathophysiological mechanisms acting at pyramidal neuron dendrites that regulate synaptic plasticity and cognition in psychotic and non-psychotic subjects. |
2016-04-19 |
2023-08-13 |
human |
| Michael Johnston, Mary E Blue, Sakkubai Naid. Recent advances in understanding synaptic abnormalities in Rett syndrome. F1000Research. vol 4. 2016-02-26. PMID:26918155. |
the disorder targets synapses and synaptic plasticity and has been shown to disrupt the balance between glutamate excitatory synapses and gabaergic inhibitory synapses. |
2016-02-26 |
2023-08-13 |
Not clear |
| Barbara Schmalbach, Eka Lepsveridze, Nevena Djogo, Giorgi Papashvili, Fang Kuang, Iryna Leshchyns'ka, Vladimir Sytnyk, Alexander G Nikonenko, Alexander Dityatev, Igor Jakovcevski, Melitta Schachne. Age-dependent loss of parvalbumin-expressing hippocampal interneurons in mice deficient in CHL1, a mental retardation and schizophrenia susceptibility gene. Journal of neurochemistry. vol 135. issue 4. 2016-02-16. PMID:26285062. |
we propose that region-specific aberrant gabaergic synaptic connectivity resulting from the mutation and a subsequently enhanced synaptic elimination during brain maturation lead to microgliosis, increase in pro-inflammatory cytokine levels, loss of interneurons, and impaired synaptic plasticity. |
2016-02-16 |
2023-08-13 |
mouse |
| Brian Charles Baculis, Carlos Fernando Valenzuel. Ethanol exposure during the third trimester equivalent does not affect GABAA or AMPA receptor-mediated spontaneous synaptic transmission in rat CA3 pyramidal neurons. Journal of negative results in biomedicine. vol 14. 2016-01-22. PMID:26627643. |
synaptic plasticity mechanisms dependent on retrograde release of brain-derived neurotrophic factor (bdnf) driven by activation of l-type voltage-gated ca(2+) channels (l-vgccs) are thought to play a role in stabilization of both gabaergic and glutamatergic synapses in ca3 pyramidal neurons. |
2016-01-22 |
2023-08-13 |
human |
| Shuxi Liu, Yue Wang, Paul F Worley, Mark P Mattson, Nicholas Gaian. The canonical Notch pathway effector RBP-J regulates neuronal plasticity and expression of GABA transporters in hippocampal networks. Hippocampus. vol 25. issue 5. 2016-01-13. PMID:25515406. |
our results reveal an essential role for canonical notch/rbp-j signaling in hippocampal synaptic plasticity and suggest that role, at least in part, is mediated by the regulation of gabaergic signaling. |
2016-01-13 |
2023-08-13 |
Not clear |
| Javier Gasulla, Daniel J Calv. Enhancement of tonic and phasic GABAergic currents following nitric oxide synthase inhibition in hippocampal CA1 pyramidal neurons. Neuroscience letters. vol 590. 2015-09-14. PMID:25636692. |
nitric oxide (no) is involved in synaptic plasticity in the hippocampus through different presynaptic and postsynaptic mechanisms that include the modulation of the gabaergic neurotransmission. |
2015-09-14 |
2023-08-13 |
mouse |
| Oleg Senkov, Pavle Andjus, Lidija Radenovic, Eduardo Soriano, Alexander Dityate. Neural ECM molecules in synaptic plasticity, learning, and memory. Progress in brain research. vol 214. 2015-08-19. PMID:25410353. |
neural extracellular matrix (ecm) molecules derived from neurons and glial cells accumulate in the extracellular space and regulate synaptic plasticity through modulation of perisomal gabaergic inhibition, intrinsic neuronal excitability, integrin signaling, and activities of l-type ca(2+) channels, nmda receptors, and rho-associated kinase. |
2015-08-19 |
2023-08-13 |
Not clear |
| Volker Neugebaue. Amygdala pain mechanisms. Handbook of experimental pharmacology. vol 227. 2015-07-27. PMID:25846623. |
impaired inhibitory control mediated by a cluster of gabaergic interneurons in the intercalated cell masses (itc) allows the development of glutamate- and neuropeptide-driven synaptic plasticity of excitatory inputs from the brainstem (parabrachial area) and from the lateral-basolateral amygdala network (la-bla, site of integration of polymodal sensory information). |
2015-07-27 |
2023-08-13 |
Not clear |
| Yan-Hua Bing, Mao-Cheng Wu, Chun-Ping Chu, De-Lai Qi. Facial stimulation induces long-term depression at cerebellar molecular layer interneuron-Purkinje cell synapses in vivo in mice. Frontiers in cellular neuroscience. vol 9. 2015-06-24. PMID:26106296. |
we studied the expression and mechanism of mli-pc gabaergic synaptic plasticity induced by a train of facial stimulation in urethane-anesthetized mice by cell-attached recordings and pharmacological methods. |
2015-06-24 |
2023-08-13 |
mouse |
| Yan-Hua Bing, Mao-Cheng Wu, Chun-Ping Chu, De-Lai Qi. Facial stimulation induces long-term depression at cerebellar molecular layer interneuron-Purkinje cell synapses in vivo in mice. Frontiers in cellular neuroscience. vol 9. 2015-06-24. PMID:26106296. |
our results suggest that the sensory stimulation-evoked mli-pc gabaergic synaptic plasticity may play a critical role in motor learning in animals. |
2015-06-24 |
2023-08-13 |
mouse |
| Jiwon Mo, Chong-Hyun Kim, Dongmin Lee, Woong Sun, Hyun Woo Lee, Hyun Ki. Early growth response 1 (Egr-1) directly regulates GABAA receptor α2, α4, and θ subunits in the hippocampus. Journal of neurochemistry. vol 133. issue 4. 2015-06-18. PMID:25708312. |
the homeostatic regulation of neuronal activity in glutamatergic and gabaergic synapses is critical for neural circuit development and synaptic plasticity. |
2015-06-18 |
2023-08-13 |
mouse |
| Andrii Rudenko, Jinsoo Seo, Ji Hu, Susan C Su, Froylan Calderon de Anda, Omer Durak, Maria Ericsson, Marie Carlén, Li-Huei Tsa. Loss of cyclin-dependent kinase 5 from parvalbumin interneurons leads to hyperinhibition, decreased anxiety, and memory impairment. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 6. 2015-04-13. PMID:25673832. |
here, we demonstrate that genetic ablation of cdk5 in pv interneurons in mouse brain leads to an increase in gabaergic neurotransmission and impaired synaptic plasticity. |
2015-04-13 |
2023-08-13 |
mouse |
| Josien Levenga, Pavan Krishnamurthy, Hameetha Rajamohamedsait, Helen Wong, Thomas F Franke, Peter Cain, Einar M Sigurdsson, Charles A Hoeffe. Tau pathology induces loss of GABAergic interneurons leading to altered synaptic plasticity and behavioral impairments. Acta neuropathologica communications. vol 1. 2015-03-31. PMID:24252661. |
tau pathology induces loss of gabaergic interneurons leading to altered synaptic plasticity and behavioral impairments. |
2015-03-31 |
2023-08-12 |
mouse |
| Benoit Souchet, Fayçal Guedj, Ignasi Sahún, Arnaud Duchon, Fabrice Daubigney, Anne Badel, Yuchio Yanagawa, Maria Jose Barallobre, Mara Dierssen, Eugene Yu, Yann Herault, Mariona Arbones, Nathalie Janel, Nicole Créau, Jean Maurice Delaba. Excitation/inhibition balance and learning are modified by Dyrk1a gene dosage. Neurobiology of disease. vol 69. 2015-03-12. PMID:24801365. |
increased expression of dyrk1a in mbactgdyrk1a induced molecular alterations in synaptic plasticity pathways, particularly expression changes in gabaergic and glutaminergic related proteins. |
2015-03-12 |
2023-08-13 |
mouse |