| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chicora F Oliver, Steven J Simmons, Sunil U Nayak, Garry R Smith, Allen B Reitz, Scott M Rawl. Chemokines and 'bath salts': CXCR4 receptor antagonist reduces rewarding and locomotor-stimulant effects of the designer cathinone MDPV in rats. Drug and alcohol dependence. vol 186. 2018-09-17. PMID:29550625. |
the chemokine cxcl12 and its principal receptor target, cxcr4, are of particular interest because cxcr4 activation enhances mesolimbic dopamine output that facilitates psychostimulant reward, reinforcement, and locomotor activation. |
2018-09-17 |
2023-08-13 |
rat |
| Armin Zlomuzica, Alla Machulska, Susanna Roberts, Michael von Glischinski, Mike Rinck, Kathryn J Lester, Thalia C Eley, Jürgen Margra. The dopamine D2 receptor mediates approach-avoidance tendencies in smokers. European archives of psychiatry and clinical neuroscience. vol 268. issue 3. 2018-09-11. PMID:28364268. |
dopamine d2 receptors (drd2) have been strongly implicated in reward processing of natural stimuli and drugs. |
2018-09-11 |
2023-08-13 |
Not clear |
| Peter J Vollbrecht, Kathryn M Nesbitt, Omar S Mabrouk, Aaron M Chadderdon, Emily M Jutkiewicz, Robert T Kennedy, Carrie R Ferrari. Cocaine and desipramine elicit distinct striatal noradrenergic and behavioral responses in selectively bred obesity-resistant and obesity-prone rats. Behavioural brain research. vol 346. 2018-09-11. PMID:29129597. |
differences in the function of brain reward circuits, including in the nucleus accumbens (nac), have been shown in obesity-prone vs. obesity-resistant populations, leading many researchers to explore the role of striatal dopamine in obesity. |
2018-09-11 |
2023-08-13 |
rat |
| Tadashi Okubo, Asako Sato, Hirotsugu Okamoto, Toshiya Sato, Toshikuni Sasaok. Differential behavioral phenotypes of dopamine D1 receptor knockdown mice at the embryonic, postnatal, and adult stages. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 66. 2018-09-07. PMID:29183706. |
dopamine is widely involved in behaviors related to motor activity, cognition, motivation, and reward. |
2018-09-07 |
2023-08-13 |
mouse |
| Marta Napierała, Joanna Bogusiewicz, Jolanta Enko, Ewa Flore. [Nicotine and caffeine: influence on dopaminergic transmission]. Przeglad lekarski. vol 73. issue 10. 2018-09-07. PMID:29689686. |
dopamine plays an important rolein the neuronal regulation of motivation/ reward, voluntary movements,cognitive processes and the processof addiction. |
2018-09-07 |
2023-08-13 |
Not clear |
| Franz Mogg. [Epidemiology, etiology and treatment of patients with psychosis and co-morbid substance use disorder]. Therapeutische Umschau. Revue therapeutique. vol 75. issue 1. 2018-09-06. PMID:29909760. |
contrary to expectations, the self-medication model was not empirically confirmed, while the psychological affect regulation model, the vulnerability-stress model of a specific sensitivity to addictive substances given a predisposition of psychosis, or the neurobiological common factor model of a dysfunction of dopamine regulation in the mesocorticolimbic reward system that predispose to primary substance use disorder found some empirical support. |
2018-09-06 |
2023-08-13 |
Not clear |
| Joel Figueroa-Quiñones, Julio Cjun. Food addiction in Latin America. Medwave. vol 18. issue 1. 2018-09-05. PMID:29499034. |
these foods activate the brain reward system in a similar way to drugs generating the release of neurotransmitters such as dopamine and oxytocin which trigger a need to repeat the behavior. |
2018-09-05 |
2023-08-13 |
Not clear |
| Ronny N Gentry, Brian Lee, Matthew R Roesc. Phasic dopamine release in the rat nucleus accumbens predicts approach and avoidance performance. Nature communications. vol 7. 2018-08-27. PMID:27786172. |
dopamine (da) is critical for reward processing, but significantly less is known about its role in punishment avoidance. |
2018-08-27 |
2023-08-13 |
rat |
| Sheng Wang, Tao Che, Anat Levit, Brian K Shoichet, Daniel Wacker, Bryan L Rot. Structure of the D2 dopamine receptor bound to the atypical antipsychotic drug risperidone. Nature. vol 555. issue 7695. 2018-08-10. PMID:29466326. |
dopamine is a neurotransmitter that has been implicated in processes as diverse as reward, addiction, control of coordinated movement, metabolism and hormonal secretion. |
2018-08-10 |
2023-08-13 |
Not clear |
| Susheel Vijayraghavan, Alex J Major, Stefan Everlin. Neuromodulation of Prefrontal Cortex in Non-Human Primates by Dopaminergic Receptors during Rule-Guided Flexible Behavior and Cognitive Control. Frontiers in neural circuits. vol 11. 2018-08-07. PMID:29259545. |
we found dissociable effects of dopamine receptors on neuronal activity for rule representation and oculomotor responses and discuss these findings in the context of prior studies that have examined the role of dopamine in spatial delayed response tasks, attention, target selection, abstract rules, visuomotor learning and reward. |
2018-08-07 |
2023-08-13 |
human |
| Chun Yun Chang, Matthew Gardner, Maria Gonzalez Di Tillio, Geoffrey Schoenbau. Optogenetic Blockade of Dopamine Transients Prevents Learning Induced by Changes in Reward Features. Current biology : CB. vol 27. issue 22. 2018-08-06. PMID:29103933. |
optogenetic blockade of dopamine transients prevents learning induced by changes in reward features. |
2018-08-06 |
2023-08-13 |
Not clear |
| Chun Yun Chang, Matthew Gardner, Maria Gonzalez Di Tillio, Geoffrey Schoenbau. Optogenetic Blockade of Dopamine Transients Prevents Learning Induced by Changes in Reward Features. Current biology : CB. vol 27. issue 22. 2018-08-06. PMID:29103933. |
however, although causal studies show that dopamine transients of 1-2 s are sufficient to drive learning about reward, these studies do not address whether they are necessary (but see [11]). |
2018-08-06 |
2023-08-13 |
Not clear |
| Chun Yun Chang, Matthew Gardner, Maria Gonzalez Di Tillio, Geoffrey Schoenbau. Optogenetic Blockade of Dopamine Transients Prevents Learning Induced by Changes in Reward Features. Current biology : CB. vol 27. issue 22. 2018-08-06. PMID:29103933. |
preventing dopamine neurons in the ventral tegmental area from firing for 5 s beginning before and continuing until after the changes in reward prevented unblocking of learning in both tasks. |
2018-08-06 |
2023-08-13 |
Not clear |
| Armin Lak, Kensaku Nomoto, Mehdi Keramati, Masamichi Sakagami, Adam Kepec. Midbrain Dopamine Neurons Signal Belief in Choice Accuracy during a Perceptual Decision. Current biology : CB. vol 27. issue 6. 2018-08-01. PMID:28285994. |
in several reinforcement learning contexts, such as pavlovian conditioning and decisions guided by reward history, this rpe signal is provided by midbrain dopamine neurons. |
2018-08-01 |
2023-08-13 |
monkey |
| Armin Lak, Kensaku Nomoto, Mehdi Keramati, Masamichi Sakagami, Adam Kepec. Midbrain Dopamine Neurons Signal Belief in Choice Accuracy during a Perceptual Decision. Current biology : CB. vol 27. issue 6. 2018-08-01. PMID:28285994. |
consequently, dopamine responses did not simply reflect a stimulus' average expected reward value but were predictive of the trial-to-trial fluctuations in perceptual accuracy. |
2018-08-01 |
2023-08-13 |
monkey |
| Armin Lak, Kensaku Nomoto, Mehdi Keramati, Masamichi Sakagami, Adam Kepec. Midbrain Dopamine Neurons Signal Belief in Choice Accuracy during a Perceptual Decision. Current biology : CB. vol 27. issue 6. 2018-08-01. PMID:28285994. |
finally, by manipulating reward size, we found that dopamine neurons reflect both the upcoming reward size and the confidence in achieving it. |
2018-08-01 |
2023-08-13 |
monkey |
| Aimilia Lydia Kalafateli, Daniel Vallöf, Julia Winsa Jörnulf, Markus Heilig, Elisabet Jerlha. A cannabinoid receptor antagonist attenuates ghrelin-induced activation of the mesolimbic dopamine system in mice. Physiology & behavior. vol 184. 2018-08-01. PMID:29221808. |
reward modulation involves the mesolimbic dopamine system, consisting of the ventral tegmental area (vta) dopamine neurons targeting nucleus accumbens (nac), a system that ghrelin activates through vta-dependent mechanisms. |
2018-08-01 |
2023-08-13 |
mouse |
| J M Wenzel, J F Chee. Endocannabinoid Regulation of Reward and Reinforcement through Interaction with Dopamine and Endogenous Opioid Signaling. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 1. 2018-07-26. PMID:28653666. |
endocannabinoid regulation of reward and reinforcement through interaction with dopamine and endogenous opioid signaling. |
2018-07-26 |
2023-08-13 |
human |
| J M Wenzel, J F Chee. Endocannabinoid Regulation of Reward and Reinforcement through Interaction with Dopamine and Endogenous Opioid Signaling. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 1. 2018-07-26. PMID:28653666. |
ecbs similarly facilitate behaviors motivated by reward through interaction with the mesolimbic dopamine (da) and endogenous opioid systems. |
2018-07-26 |
2023-08-13 |
human |
| Mario Widmer, Samara Stulz, Andreas R Luft, Kai Lut. Elderly adults show higher ventral striatal activation in response to motor performance related rewards than young adults. Neuroscience letters. vol 661. 2018-07-26. PMID:28939388. |
aging is associated with changes of the reward system, including striatal and extrastriatal loss of dopamine receptors. |
2018-07-26 |
2023-08-13 |
human |