| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hiroaki Masuzaki, Chisayo Kozuka, Shiki Okamoto, Masato Yonamine, Hideaki Tanaka, Michio Shimabukur. Brown rice-specific γ-oryzanol as a promising prophylactic avenue to protect against diabetes mellitus and obesity in humans. Journal of diabetes investigation. vol 10. issue 1. 2019-02-14. PMID:29978570. |
because dopamine d2 receptor signaling in the brain reward system is considerably attenuated in obese humans and rodents, γ-oryzanol might represent a unique property to ameliorate both hedonic and metabolic dysregulation of feeding behavior, highlighting a promising prophylactic avenue to protect against metabolic derangement. |
2019-02-14 |
2023-08-13 |
mouse |
| Angela J Langdon, Melissa J Sharpe, Geoffrey Schoenbaum, Yael Ni. Model-based predictions for dopamine. Current opinion in neurobiology. vol 49. 2019-02-11. PMID:29096115. |
however, a number of recent findings highlight the influence of model-based computations on dopamine responses, and suggest that dopamine prediction errors reflect more dimensions of an expected outcome than scalar reward value. |
2019-02-11 |
2023-08-13 |
Not clear |
| W R Stauffe. The biological and behavioral computations that influence dopamine responses. Current opinion in neurobiology. vol 49. 2019-02-11. PMID:29505948. |
phasic dopamine responses demonstrate remarkable simplicity; they code for the differences between received and predicted reward values. |
2019-02-11 |
2023-08-13 |
monkey |
| Taku Nagai, Kiyofumi Yamada, Kozo Kaibuch. Reward signals downstream of dopamine D1 receptors. Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence. vol 51. issue 6. 2019-02-11. PMID:30461245. |
reward signals downstream of dopamine d1 receptors. |
2019-02-11 |
2023-08-13 |
Not clear |
| Xiaojie Liu, Yan Li, Laikang Yu, Casey R Vickstrom, Qing-Song Li. VTA mTOR Signaling Regulates Dopamine Dynamics, Cocaine-Induced Synaptic Alterations, and Reward. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 43. issue 5. 2019-02-06. PMID:29039413. |
vta mtor signaling regulates dopamine dynamics, cocaine-induced synaptic alterations, and reward. |
2019-02-06 |
2023-08-13 |
Not clear |
| Suchan Chang, Yeonhee Ryu, Young Seob Gwak, Nam Jun Kim, Jin Mook Kim, Jun Yeon Lee, Seol Ah Kim, Bong Hyo Lee, Scott C Steffensen, Eun Young Jang, Chae Ha Yang, Hee Young Ki. Spinal pathways involved in somatosensory inhibition of the psychomotor actions of cocaine. Scientific reports. vol 7. issue 1. 2019-02-04. PMID:28706288. |
previous studies have demonstrated that somatosensory stimuli influence dopamine transmission in the mesolimbic reward system and can reduce drug-induced motor behaviors, craving and dependence. |
2019-02-04 |
2023-08-13 |
Not clear |
| Danielle O Sambo, Joseph J Lebowitz, Habibeh Khoshboue. The sigma-1 receptor as a regulator of dopamine neurotransmission: A potential therapeutic target for methamphetamine addiction. Pharmacology & therapeutics. vol 186. 2019-02-04. PMID:29360540. |
meth is a potent psychostimulant that increases extracellular dopamine levels by targeting the dopamine transporter (dat) and alters neuronal activity in the reward centers of the brain. |
2019-02-04 |
2023-08-13 |
Not clear |
| Jodi R Godfrey, Maylen Perez Diaz, Melanie Pincus, Zsofia Kovacs-Balint, Eric Feczko, Eric Earl, Oscar Miranda-Dominguez, Damien Fair, Mar M Sanchez, Mark E Wilson, Vasiliki Michopoulo. Diet matters: Glucocorticoid-related neuroadaptations associated with calorie intake in female rhesus monkeys. Psychoneuroendocrinology. vol 91. 2019-02-04. PMID:29567621. |
while consumption of an obesogenic diet and chronic stress have both been shown to decrease dopamine 2 receptor (d2r) binding and alter functional connectivity (fc) within the prefrontal cortex (pfc) and the nucleus accumbens (nacc), it remains uncertain how social experience and dietary environment interact to affect reward pathways critical for the regulation of motivated behavior. |
2019-02-04 |
2023-08-13 |
monkey |
| Joonas Majuri, Juho Joutsa, Eveliina Arponen, Sarita Forsback, Valtteri Kaasine. Dopamine synthesis capacity correlates with µ-opioid receptor availability in the human basal ganglia: A triple-tracer PET study. NeuroImage. vol 183. 2019-02-04. PMID:30077742. |
animal studies have suggested that dopamine and opioid neurotransmitter systems interact in brain regions that are relevant for reward functions, but data in humans are very limited. |
2019-02-04 |
2023-08-13 |
human |
| Vincenzo G Fiore, Tobias Nolte, Francesco Rigoli, Peter Smittenaar, Xiaosi Gu, Raymond J Dola. Value encoding in the globus pallidus: fMRI reveals an interaction effect between reward and dopamine drive. NeuroImage. vol 173. 2019-01-28. PMID:29481966. |
value encoding in the globus pallidus: fmri reveals an interaction effect between reward and dopamine drive. |
2019-01-28 |
2023-08-13 |
human |
| Vincenzo G Fiore, Tobias Nolte, Francesco Rigoli, Peter Smittenaar, Xiaosi Gu, Raymond J Dola. Value encoding in the globus pallidus: fMRI reveals an interaction effect between reward and dopamine drive. NeuroImage. vol 173. 2019-01-28. PMID:29481966. |
to test this prediction, we used an fmri paradigm involving a within-subject placebo-controlled design, using the dopamine antagonist risperidone, wherein healthy volunteers performed a motor selection and maintenance task under low and high reward conditions. |
2019-01-28 |
2023-08-13 |
human |
| Vincenzo G Fiore, Tobias Nolte, Francesco Rigoli, Peter Smittenaar, Xiaosi Gu, Raymond J Dola. Value encoding in the globus pallidus: fMRI reveals an interaction effect between reward and dopamine drive. NeuroImage. vol 173. 2019-01-28. PMID:29481966. |
roi-based fmri analysis revealed an interaction between reward and dopamine drive manipulations, with increased bold activity in gpe in a high compared to low reward condition, and under risperidone compared to placebo. |
2019-01-28 |
2023-08-13 |
human |
| Rafat A Mohammed Jawad, Claire V Hutchinson, Jose Prado. Dissociation of place preference and tolerance responses to sucrose using a dopamine antagonist in the planarian. Psychopharmacology. vol 235. issue 3. 2019-01-25. PMID:29197982. |
however, comparing animals treated with dopamine d1 antagonist (sch-23390) with control animals showed that the establishment of cpp, but not the development of tolerance, is mediated by the dopamine reward system. |
2019-01-25 |
2023-08-13 |
Not clear |
| Graziella Quattrocchi, Jessica Monaco, Andy Ho, Friederike Irmen, Wolfgang Strube, Diane Ruge, Sven Bestmann, Joseph M Gale. Pharmacological Dopamine Manipulation Does Not Alter Reward-Based Improvements in Memory Retention during a Visuomotor Adaptation Task. eNeuro. vol 5. issue 3. 2019-01-25. PMID:30027109. |
we confirmed previous evidence that reward enhances retention, but the dopamine (da) precursor levodopa (ld) or the da antagonist haloperidol failed to influence performance. |
2019-01-25 |
2023-08-13 |
human |
| Enith Espinosa, Kathleen S Curti. Increased locomotor activity in estrogen-treated ovariectomized rats is associated with nucleus accumbens dopamine and is not reduced by dietary sodium deprivation. Integrative zoology. vol 13. issue 6. 2019-01-18. PMID:29851282. |
thus, the estrogen-induced increase in locomotion is a robust phenomenon that is not inhibited by a body sodium challenge and is associated with elevated levels of dopamine in reward pathways. |
2019-01-18 |
2023-08-13 |
rat |
| Vikas Navratna, Dilip K Tosh, Kenneth A Jacobson, Eric Gouau. Thermostabilization and purification of the human dopamine transporter (hDAT) in an inhibitor and allosteric ligand bound conformation. PloS one. vol 13. issue 7. 2019-01-17. PMID:29965988. |
dopamine is an essential monoamine chemical messenger that regulates reward seeking behavior, motor control, hormonal release, and emotional response in humans. |
2019-01-17 |
2023-08-13 |
human |
| David Kappel, Robert Legenstein, Stefan Habenschuss, Michael Hsieh, Wolfgang Maas. A Dynamic Connectome Supports the Emergence of Stable Computational Function of Neural Circuits through Reward-Based Learning. eNeuro. vol 5. issue 2. 2019-01-11. PMID:29696150. |
we show that spontaneous synapse-autonomous processes, in combination with reward signals such as dopamine, can explain the capability of networks of neurons in the brain to configure themselves for specific computational tasks, and to compensate automatically for later changes in the network or task. |
2019-01-11 |
2023-08-13 |
Not clear |
| Ray Luo, Akira Uematsu, Adam Weitemier, Luca Aquili, Jenny Koivumaa, Thomas J McHugh, Joshua P Johanse. A dopaminergic switch for fear to safety transitions. Nature communications. vol 9. issue 1. 2019-01-11. PMID:29950562. |
this demonstrates a novel function for the canonical vta-dopamine reward system and reveals opposing behavioral roles for different dopamine neuron projections in fear extinction learning. |
2019-01-11 |
2023-08-13 |
Not clear |
| Kenji Morita, Ayaka Kat. A Neural Circuit Mechanism for the Involvements of Dopamine in Effort-Related Choices: Decay of Learned Values, Secondary Effects of Depletion, and Calculation of Temporal Difference Error. eNeuro. vol 5. issue 1. 2019-01-09. PMID:29468191. |
key findings are that dopamine depletion (i) changed preference for a high-cost, large-reward option to a low-cost, small-reward option, (ii) but not when the large-reward option was also low-cost or the small-reward option gave no reward, (iii) while increasing the latency in all the cases but only transiently, and (iv) that antagonism of either dopamine d1 or d2 receptors also specifically impaired selection of the high-cost, large-reward option. |
2019-01-09 |
2023-08-13 |
Not clear |
| Kenji Morita, Ayaka Kat. A Neural Circuit Mechanism for the Involvements of Dopamine in Effort-Related Choices: Decay of Learned Values, Secondary Effects of Depletion, and Calculation of Temporal Difference Error. eNeuro. vol 5. issue 1. 2019-01-09. PMID:29468191. |
the former is potentially caused by background neural activity-induced weak synaptic plasticity, and the latter is assumed to occur through post-depletion increase of neural activity in the pedunculopontine nucleus, where neurons representing obtained reward exist and presumably send excitatory projections to dopamine neurons. |
2019-01-09 |
2023-08-13 |
Not clear |