| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D E Comings, D Muhleman, R Gade, P Johnson, R Verde, G Saucier, J MacMurra. Cannabinoid receptor gene (CNR1): association with i.v. drug use. Molecular psychiatry. vol 2. issue 2. 1997-07-30. PMID:9106242. |
the results are consistent with a role of cannabinoid receptors in the modulation of dopamine and cannabinoid reward pathways. |
1997-07-30 |
2023-08-12 |
human |
| K Blum, E R Braverman, S Wu, J G Cull, T J Chen, J Gill, R Wood, A Eisenberg, M Sherman, K R Davis, D Matthews, L Fischer, N Schnautz, W Walsh, A A Pontius, M Zedar, G Kaats, D E Coming. Association of polymorphisms of dopamine D2 receptor (DRD2), and dopamine transporter (DAT1) genes with schizoid/avoidant behaviors (SAB). Molecular psychiatry. vol 2. issue 3. 1997-07-30. PMID:9152988. |
the dopaminergic system, and in particular the dopamine d2 receptor, has been implicated in reward mechanisms in the brain. |
1997-07-30 |
2023-08-12 |
Not clear |
| P A Broderick, C F Pheli. I. Serotonin (5-HT) within dopamine reward circuits signals open-field behavior. II. Basis for 5-HT--DA interaction in cocaine dysfunctional behavior. Neuroscience and biobehavioral reviews. vol 21. issue 3. 1997-07-21. PMID:9168262. |
i. serotonin (5-ht) within dopamine reward circuits signals open-field behavior. |
1997-07-21 |
2023-08-12 |
Not clear |
| L J Vanderschuren, R J Niesink, J M Van Re. The neurobiology of social play behavior in rats. Neuroscience and biobehavioral reviews. vol 21. issue 3. 1997-07-21. PMID:9168267. |
evidence is presented that opioid and dopamine systems play a role in the reward aspect of social play behavior. |
1997-07-21 |
2023-08-12 |
rat |
| W Schult. Dopamine neurons and their role in reward mechanisms. Current opinion in neurobiology. vol 7. issue 2. 1997-06-27. PMID:9142754. |
dopamine neurons and their role in reward mechanisms. |
1997-06-27 |
2023-08-12 |
Not clear |
| N D Volkow, G J Wang, J S Fowler, J Logan, S J Gatley, R Hitzemann, A D Chen, S L Dewey, N Pappa. Decreased striatal dopaminergic responsiveness in detoxified cocaine-dependent subjects. Nature. vol 386. issue 6627. 1997-05-22. PMID:9126741. |
cocaine blocks the reuptake of dopamine, a neurotransmitter involved in the control of movement, cognition, motivation and reward. |
1997-05-22 |
2023-08-12 |
human |
| R P Ebstein, R Segman, J Benjamin, Y Osher, L Nemanov, R H Belmake. 5-HT2C (HTR2C) serotonin receptor gene polymorphism associated with the human personality trait of reward dependence: interaction with dopamine D4 receptor (D4DR) and dopamine D3 receptor (D3DR) polymorphisms. American journal of medical genetics. vol 74. issue 1. 1997-04-30. PMID:9034010. |
5-ht2c (htr2c) serotonin receptor gene polymorphism associated with the human personality trait of reward dependence: interaction with dopamine d4 receptor (d4dr) and dopamine d3 receptor (d3dr) polymorphisms. |
1997-04-30 |
2023-08-12 |
human |
| E P Bless, K A McGinnis, A L Mitchell, A Hartwell, J B Mitchel. The effects of gonadal steroids on brain stimulation reward in female rats. Behavioural brain research. vol 82. issue 2. 1997-04-25. PMID:9030405. |
the present study examined possible estrogen and/or progesterone effects on the mesolimbic dopamine (da) system using brain stimulation reward (bsr). |
1997-04-25 |
2023-08-12 |
rat |
| G F Koo. Hedonic valence, dopamine and motivation. Molecular psychiatry. vol 1. issue 3. 1997-04-22. PMID:9118342. |
dopamine neurons in the dopamine system that originate in the ventral tegmental area and project to the nucleus accumbens, olfactory tubercle and frontal cortex have long been implicated in reward and motivational processes. |
1997-04-22 |
2023-08-12 |
Not clear |
| G Le Pen, D Duterte-Boucher, J Costenti. Place conditioning with cocaine and the dopamine uptake inhibitor GBR12783. Neuroreport. vol 7. issue 18. 1997-04-18. PMID:9116192. |
this confirms the involvement of dopamine uptake inhibition in reward, but underlines differences in relative efficacies in rewarding and motor effects of both drugs and suggests that these two properties are, at least in part, separable anatomically or functionally. |
1997-04-18 |
2023-08-12 |
Not clear |
| L Chai, W S Choi, O K Rönneklei. Maternal cocaine treatment alters dynorphin and enkephalin mRNA expression in brains of fetal rhesus macaques. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 17. issue 3. 1997-03-17. PMID:8994065. |
changes in the expression of these opioid peptides in presumed dopamine target neurons, which mediate motivation and reward, as well as motor control, provide further evidence for profound consequences of in utero cocaine exposure on the developing dopamine neurocircuitry. |
1997-03-17 |
2023-08-12 |
monkey |
| S S Baum, R Hill, H Rommelspache. Harman-induced changes of extracellular concentrations of neurotransmitters in the nucleus accumbens of rats. European journal of pharmacology. vol 314. issue 1-2. 1997-03-10. PMID:8957221. |
in vivo microdialysis was used to investigate the effects of acute injections of harman (1-methyl-beta-carboline) on extraneuronal concentrations of dopamine and 5-hydroxytryptamine in the nucleus accumbens, which in part the mesolimbic reward system. |
1997-03-10 |
2023-08-12 |
rat |
| A M Persico, G Bird, F H Gabbay, G R Uh. D2 dopamine receptor gene TaqI A1 and B1 restriction fragment length polymorphisms: enhanced frequencies in psychostimulant-preferring polysubstance abusers. Biological psychiatry. vol 40. issue 8. 1997-02-21. PMID:8894071. |
psychostimulants display the most robust enhancement of dopamine activity in mesolimbic/mesocortical circuits important for behavioral reward. |
1997-02-21 |
2023-08-12 |
Not clear |
| S R White, T Obradovic, K M Imel, M J Wheato. The effects of methylenedioxymethamphetamine (MDMA, "Ecstasy") on monoaminergic neurotransmission in the central nervous system. Progress in neurobiology. vol 49. issue 5. 1997-02-19. PMID:8895996. |
experiments in awake, behaving laboratory animals have demonstrated that single injections of mdma increase extracellular levels of the neurotransmitters dopamine (da) and serotonin (5ht) in the nucleus accumbens and in several other brain regions that are important for reward. |
1997-02-19 |
2023-08-12 |
Not clear |
| T Kivastik, K Vuorikallas, T P Piepponen, A Zharkovsky, L Ahte. Morphine- and cocaine-induced conditioned place preference: effects of quinpirole and preclamol. Pharmacology, biochemistry, and behavior. vol 54. issue 2. 1997-02-12. PMID:8743597. |
the role of dopamine in opioid reward is unresolved. |
1997-02-12 |
2023-08-12 |
rat |
| P R Montague, P Dayan, T J Sejnowsk. A framework for mesencephalic dopamine systems based on predictive Hebbian learning. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 5. 1997-01-03. PMID:8774460. |
in particular, we show how activity in the cerebral cortex can make predictions about future receipt of reward and how fluctuations in the activity levels of neurons in diffuse dopamine systems above and below baseline levels would represent errors in these predictions that are delivered to cortical and subcortical targets. |
1997-01-03 |
2023-08-12 |
human |
| C Perrone-Capano, U di Porzi. Epigenetic factors and midbrain dopaminergic neurone development. BioEssays : news and reviews in molecular, cellular and developmental biology. vol 18. issue 10. 1996-12-16. PMID:8885719. |
in the mammalian brain dopamine systems play a central role in the control of movement, hormone release, emotional balance and reward. |
1996-12-16 |
2023-08-12 |
Not clear |
| W Gong, D Neill, J B Justic. Conditioned place preference and locomotor activation produced by injection of psychostimulants into ventral pallidum. Brain research. vol 707. issue 1. 1996-12-13. PMID:8866714. |
these results support the idea of an involvement of dopamine in vp in reward and locomotor activation, independent of dopamine in nas. |
1996-12-13 |
2023-08-12 |
Not clear |
| J K Staley, D C Mas. Adaptive increase in D3 dopamine receptors in the brain reward circuits of human cocaine fatalities. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 19. 1996-12-06. PMID:8815892. |
adaptive increase in d3 dopamine receptors in the brain reward circuits of human cocaine fatalities. |
1996-12-06 |
2023-08-12 |
human |
| L G Schmidt, M Dettling, K J Graef, A Heinz, S Kuhn, J Podschus, H Rommelspache. Reduced dopaminergic function in alcoholics is related to severe dependence. Biological psychiatry. vol 39. issue 3. 1996-12-05. PMID:8837980. |
with a view to the role of dopamine (da) systems in reward processes and considering recent studies linking specific alleles at the da-d2 receptor gene locus with alcoholism (especially with severe types) dopaminergic functions were evaluated in 49 alcoholics using growth hormone (gh) response to da receptor agonist apomorphine (0.01 mg/kg subcutaneously). |
1996-12-05 |
2023-08-12 |
Not clear |