| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Michaeli, R Yak. Dopamine inhibits GABA(A) currents in ventral tegmental area dopamine neurons via activation of presynaptic G-protein coupled inwardly-rectifying potassium channels. Neuroscience. vol 165. issue 4. 2010-03-12. PMID:19944748. |
dopamine (da) neurons in the ventral tegmental area (vta) constitute the origin of major dopaminergic neural pathways associated with essential functions including reward, motivation and cognition. |
2010-03-12 |
2023-08-12 |
rat |
| Eric Stice, Alain Daghe. Genetic variation in dopaminergic reward in humans. Forum of nutrition. vol 63. 2010-03-04. PMID:19955785. |
in addition, there is emerging fmri evidence that reduced responsivity in brain regions implicated in food reward increase risk for future weight gain among individuals who appear to be at genetic risk for attenuated dopamine signaling by virtue of drd2 and drd4 genotypes. |
2010-03-04 |
2023-08-12 |
Not clear |
| Brandon J Aragona, Jeremy J Day, Mitchell F Roitman, Nathan A Cleaveland, R Mark Wightman, Regina M Carell. Regional specificity in the real-time development of phasic dopamine transmission patterns during acquisition of a cue-cocaine association in rats. The European journal of neuroscience. vol 30. issue 10. 2010-02-26. PMID:19912327. |
drug seeking is significantly regulated by drug-associated cues and associative learning between environmental cues and cocaine reward is mediated by dopamine transmission within the nucleus accumbens (nac). |
2010-02-26 |
2023-08-12 |
rat |
| Susan R Sesack, Anthony A Grac. Cortico-Basal Ganglia reward network: microcircuitry. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 1. 2010-02-24. PMID:19675534. |
conditions that result in reward promote phasic dopamine release, which serves to maintain ongoing behavior by selectively potentiating ventral subicular drive to the accumbens. |
2010-02-24 |
2023-08-12 |
Not clear |
| Susan R Sesack, Anthony A Grac. Cortico-Basal Ganglia reward network: microcircuitry. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 1. 2010-02-24. PMID:19675534. |
behaviors that fail to produce an expected reward decrease dopamine transmission, which favors prefrontal cortical-driven switching to new behavioral strategies. |
2010-02-24 |
2023-08-12 |
Not clear |
| J Ng, A J Rashid, C H So, B F O'Dowd, S R Georg. Activation of calcium/calmodulin-dependent protein kinase IIalpha in the striatum by the heteromeric D1-D2 dopamine receptor complex. Neuroscience. vol 165. issue 2. 2010-02-24. PMID:19837142. |
the identification of this novel mechanism by which dopamine may modulate synaptic plasticity has implications for our understanding of striatal-mediated reward and motor function, as well as neuronal disorders in which striatal dopaminergic neurotransmission is involved. |
2010-02-24 |
2023-08-12 |
Not clear |
| D A Peterson, C Elliott, D D Song, S Makeig, T J Sejnowski, H Poizne. Probabilistic reversal learning is impaired in Parkinson's disease. Neuroscience. vol 163. issue 4. 2010-02-12. PMID:19628022. |
we sought to investigate how the dopamine depletion in parkinson's disease (pd) affects probabilistic reward learning and adaptation to a reversal in reward contingencies. |
2010-02-12 |
2023-08-12 |
human |
| Birgit Abler, Bärbel Herrnberger, Georg Grön, Manfred Spitze. From uncertainty to reward: BOLD characteristics differentiate signaling pathways. BMC neuroscience. vol 10. 2010-02-12. PMID:20028546. |
reward value and uncertainty are represented by dopamine neurons in monkeys by distinct phasic and tonic firing rates. |
2010-02-12 |
2023-08-12 |
human |
| Robin S Gill, Marilyn S Hsiung, Chi S Sum, Natalie Lavine, Stewart D Clark, Hubert H M Van To. The dopamine D4 receptor activates intracellular platelet-derived growth factor receptor beta to stimulate ERK1/2. Cellular signalling. vol 22. issue 2. 2010-02-03. PMID:19782129. |
dopamine receptors are gpcrs that play important roles in locomotion, reward, and cognitive processes. |
2010-02-03 |
2023-08-12 |
Not clear |
| Miriam Melis, Marco Diana, Paolo Enrico, Michela Marinelli, Mark S Brodi. Ethanol and acetaldehyde action on central dopamine systems: mechanisms, modulation, and relationship to stress. Alcohol (Fayetteville, N.Y.). vol 43. issue 7. 2010-01-28. PMID:19913196. |
there has been a great deal of activity in recent years in the study of the direct effects of ethanol on the dopamine reward system originating in the ventral tegmental area (vta). |
2010-01-28 |
2023-08-12 |
Not clear |
| Carsten Calaminus, Wolfgang Haube. Modulation of behavior by expected reward magnitude depends on dopamine in the dorsomedial striatum. Neurotoxicity research. vol 15. issue 2. 2010-01-26. PMID:19384572. |
modulation of behavior by expected reward magnitude depends on dopamine in the dorsomedial striatum. |
2010-01-26 |
2023-08-12 |
rat |
| Carsten Calaminus, Wolfgang Haube. Modulation of behavior by expected reward magnitude depends on dopamine in the dorsomedial striatum. Neurotoxicity research. vol 15. issue 2. 2010-01-26. PMID:19384572. |
results showed that pdms dopamine depletion impaired reward-dependent modulation of reaction times, if visual cues predict large versus small reward, but not if visual cues predict reward versus no reward. |
2010-01-26 |
2023-08-12 |
rat |
| Carsten Calaminus, Wolfgang Haube. Modulation of behavior by expected reward magnitude depends on dopamine in the dorsomedial striatum. Neurotoxicity research. vol 15. issue 2. 2010-01-26. PMID:19384572. |
these observations suggest that dopamine signaling in the pdms contributes to a process through which reward-directed responses become guided by cues associated with distinct reward magnitudes. |
2010-01-26 |
2023-08-12 |
rat |
| Carsten Calaminus, Wolfgang Haube. Modulation of behavior by expected reward magnitude depends on dopamine in the dorsomedial striatum. Neurotoxicity research. vol 15. issue 2. 2010-01-26. PMID:19384572. |
experiment 2 revealed that pdms dopamine depletion did not compromise the acquisition of a conditional visual discrimination task in an operant box that required learning a rule of the type "if the cue light is bright press left lever for reward, if dim press right lever". |
2010-01-26 |
2023-08-12 |
rat |
| Carsten Calaminus, Wolfgang Haube. Modulation of behavior by expected reward magnitude depends on dopamine in the dorsomedial striatum. Neurotoxicity research. vol 15. issue 2. 2010-01-26. PMID:19384572. |
furthermore, experiment 3 showed that pdms dopamine depletion did not impair the acquisition of a cross maze task that required learning a visual cue discrimination strategy to obtain food reward. |
2010-01-26 |
2023-08-12 |
rat |
| Samuele Cortese, F Xavier Castellano. Dopamine reward pathway in adult ADHD. JAMA. vol 303. issue 3. 2010-01-26. PMID:20085951. |
dopamine reward pathway in adult adhd. |
2010-01-26 |
2023-08-12 |
Not clear |
| Alan J Zametki. Dopamine reward pathway in adult ADHD. JAMA. vol 303. issue 3. 2010-01-26. PMID:20085952. |
dopamine reward pathway in adult adhd. |
2010-01-26 |
2023-08-12 |
Not clear |
| Ian C Webb, Ricardo M Baltazar, Xu Wang, Kyle K Pitchers, Lique M Coolen, Michael N Lehma. Diurnal variations in natural and drug reward, mesolimbic tyrosine hydroxylase, and clock gene expression in the male rat. Journal of biological rhythms. vol 24. issue 6. 2010-01-20. PMID:19926806. |
the phase relationships between reward rhythms and mesolimbic th protein levels suggest that an increased capacity for the release of dopamine in the nacc may underlie the rhythms in sex-related reward, while amphetamine-related reward occurs at a time when the likelihood of evoked nacc da release is relatively low. |
2010-01-20 |
2023-08-12 |
rat |
| Gregor Hasler, Krystal Mondillo, Wayne C Drevets, James R Blai. Impairments of probabilistic response reversal and passive avoidance following catecholamine depletion. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 13. 2010-01-19. PMID:19675538. |
catecholamines, particularly dopamine, have been implicated in various aspects of the reward function including the ability to learn through reinforcement and to modify flexibly responses to changing reinforcement contingencies. |
2010-01-19 |
2023-08-12 |
human |
| Sang Soo Cho, Antonio P Strafell. rTMS of the left dorsolateral prefrontal cortex modulates dopamine release in the ipsilateral anterior cingulate cortex and orbitofrontal cortex. PloS one. vol 4. issue 8. 2010-01-19. PMID:19696930. |
brain dopamine is implicated in the regulation of movement, attention, reward and learning and plays an important role in parkinson's disease, schizophrenia and drug addiction. |
2010-01-19 |
2023-08-12 |
Not clear |