| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Freddyson J Martínez-Rivera, Yun Young Yim, Arthur Godino, Angélica Minier-Toribio, Solange Tofani, Leanne M Holt, Angélica Torres-Berrío, Rita Futamura, Caleb J Browne, Tamara Markovic, Peter J Hamilton, Rachael L Neve, Eric J Nestle. Cell-Type-Specific Regulation of Cocaine Reward by the E2F3a Transcription Factor in Nucleus Accumbens. bioRxiv : the preprint server for biology. 2024-07-19. PMID:39026727. |
cell-type-specific regulation of cocaine reward by the e2f3a transcription factor in nucleus accumbens. |
2024-07-19 |
2024-07-21 |
mouse |
| Freddyson J Martínez-Rivera, Yun Young Yim, Arthur Godino, Angélica Minier-Toribio, Solange Tofani, Leanne M Holt, Angélica Torres-Berrío, Rita Futamura, Caleb J Browne, Tamara Markovic, Peter J Hamilton, Rachael L Neve, Eric J Nestle. Cell-Type-Specific Regulation of Cocaine Reward by the E2F3a Transcription Factor in Nucleus Accumbens. bioRxiv : the preprint server for biology. 2024-07-19. PMID:39026727. |
these neurobiological processes in brain reward regions, such as the nucleus accumbens (nac), are orchestrated in large part by transcriptional regulation. |
2024-07-19 |
2024-07-21 |
mouse |
| Heather C Aziz, Regina A Mangier. Sex differences in membrane properties and cellular excitability of dopamine D1 receptor-expressing neurons within the shell of the nucleus accumbens of pre- and mid-adolescent mice. Biology of sex differences. vol 15. issue 1. 2024-07-13. PMID:39003495. |
the nucleus accumbens (nac), a striatal brain region composed of the core (nacc) and shell (nacsh), has been linked to risk-taking behavior and implicated in reward seeking and evaluation. |
2024-07-13 |
2024-07-16 |
mouse |
| Kimberly L P Long, Nerissa E G Hoglen, Alex J Keip, Robert M Klinkel, DéJenaé L See, Joseph Maa, Jenna C Wong, Michael Sherman, Devanand S Manol. Oxytocin receptor function regulates neural signatures of pair bonding and fidelity in the nucleus accumbens. bioRxiv : the preprint server for biology. 2024-07-09. PMID:38979148. |
signaling via the oxytocin receptor (oxtr) in the nucleus accumbens (nac) facilitates social reward as well as pair bond formation between mates in socially monogamous prairie voles |
2024-07-09 |
2024-07-12 |
Not clear |
| Sarah Witley, Christian E Edvardsson, Cajsa Aranäs, Maximilian Tufvesson-Alm, Darta Stalberga, Henrik Green, Jesper Vestlund, Elisabet Jerlha. Des-acyl ghrelin reduces alcohol intake and alcohol-induced reward in rodents. Translational psychiatry. vol 14. issue 1. 2024-07-04. PMID:38965230. |
the role of dag in reward processing is further supported as dag prevents alcohol-induced locomotor stimulation, reward in the conditioned place preference paradigm, and dopamine release in the nucleus accumbens in male rodents. |
2024-07-04 |
2024-07-08 |
rat |
| Nur Abdel-Hay, Marina Kabirova, Rami Yak. A discrete subpopulation of PFC-LHb neurons govern cocaine place preference. Translational psychiatry. vol 14. issue 1. 2024-07-02. PMID:38956048. |
the pfc interacts with the brain's reward system, including the ventral tegmental area (vta) and nucleus accumbens (nac). |
2024-07-02 |
2024-07-06 |
Not clear |
| Kasey L Brida, Emily T Jorgensen, Robert A Phillips, Catherine E Newman, Jennifer J Tuscher, Emily K Morring, Morgan E Zipperly, Lara Ianov, Kelsey D Montgomery, Madhavi Tippani, Thomas M Hyde, Kristen R Maynard, Keri Martinowich, Jeremy J Da. Reelin marks cocaine-activated striatal ensembles, promotes neuronal excitability, and regulates cocaine reward. bioRxiv : the preprint server for biology. 2024-07-01. PMID:38948801. |
drugs of abuse activate defined neuronal ensembles in brain reward structures such as the nucleus accumbens (nac), which are thought to promote the enduring synaptic, circuit, and behavioral consequences of drug exposure. |
2024-07-01 |
2024-07-03 |
Not clear |
| Sydney E Ashton, Paul Sharalla, Naru Kang, Adam T Brockett, Margaret M McCarthy, Matthew R Roesc. Distinct action signals by subregions in nucleus accumbens during STOP-change performance. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-06-19. PMID:38897724. |
nucleus accumbens (nac) is thought to contribute to motivated behavior by signaling the value of reward-predicting cues and the delivery of anticipated reward. |
2024-06-19 |
2024-06-22 |
rat |
| Brandon Taraku, Joana R Loureiro, Ashish K Sahib, Artemis Zavaliangos-Petropulu, Noor Al-Sharif, Amber M Leaver, Benjamin Wade, Shantanu Joshi, Roger P Woods, Randall Espinoza, Katherine L Nar. Modulation of habenular and nucleus accumbens functional connectivity by ketamine in major depression. Brain and behavior. vol 14. issue 6. 2024-06-19. PMID:38894648. |
major depressive disorder (mdd) is associated with dysfunctional reward processing, which involves functional circuitry of the habenula (hb) and nucleus accumbens (nac). |
2024-06-19 |
2024-06-21 |
Not clear |
| Nicolette Driscoll, Marc-Joseph Antonini, Taylor M Cannon, Pema Maretich, Greatness Olaitan, Valerie Doan Phi Van, Keisuke Nagao, Atharva Sahasrabudhe, Emmanuel Vargas, Sydney Hunt, Melissa Hummel, Sanju Mupparaju, Alan Jasanoff, Jill Venton, Polina Anikeev. Fiber-based Probes for Electrophysiology, Photometry, Optical and Electrical Stimulation, Drug Delivery, and Fast-Scan Cyclic Voltammetry In Vivo. bioRxiv : the preprint server for biology. 2024-06-19. PMID:38895451. |
their utility is demonstrated in studies of the mesolimbic reward pathway by simultaneously interfacing with the ventral tegmental area and nucleus accumbens in mice and characterizing the neurophysiological effects of a stimulant drug. |
2024-06-19 |
2024-06-21 |
mouse |
| Avril Gagnon-Chauvin, Mathieu Fornasier-Bélanger, Sandra W Jacobson, Joseph L Jacobson, Yohann Courtemanche, Pierre Ayotte, Richard E Bélanger, Gina Muckle, Dave Saint-Amou. Brain gray matter volume of reward-related structures in Inuit adolescents pre- and postnatally exposed to lead, mercury and polychlorinated biphenyls. Neurotoxicology. 2024-06-16. PMID:38880197. |
this study aimed to assess associations between prenatal and postnatal exposure to lead (pb), mercury (hg) and polychlorinated biphenyls (pcbs) and gray matter volume of key regions of the brain reward circuit, namely the caudate nucleus, putamen, nucleus accumbens (nacc), the amygdala, the orbitofrontal cortex (ofc) and the anterior cingulate cortex (acc). |
2024-06-16 |
2024-06-19 |
Not clear |
| Justin P Yuan, Emma L Jaeger, Saché M Coury, Jessica P Uy, Jessica L Buthmann, Tiffany C Ho, Ian H Gotli. Socioeconomic Disadvantage Moderates the Association of Systemic Inflammation with Amygdala Volume in Adolescents Over a Two-Year Interval: An Exploratory Study. Biological psychiatry. Cognitive neuroscience and neuroimaging. 2024-06-11. PMID:38815859. |
affective areas of the brain involved in processing threat (e.g., amygdala) and reward (e.g., nucleus accumbens [nacc]) appear to be sensitive to inflammation. |
2024-06-11 |
2024-06-14 |
Not clear |
| Isabel C Duarte, Ana Dionísio, Joana Oliveira, Marco Simões, Rita Correia, Joana A Dias, Salomé Caldeira, João Redondo, Miguel Castelo-Branc. Neural underpinnings of ethical decisions in life and death dilemmas in naïve and expert firefighters. Scientific reports. vol 14. issue 1. 2024-06-08. PMID:38851794. |
these realistic life-saving dilemmas activate the same core reward and affective processing network, in particular the ventromedial prefrontal cortex, nucleus accumbens and amygdala, irrespective of prior expertise, thereby supporting general domain theories of ethical decision-making. |
2024-06-08 |
2024-06-11 |
Not clear |
| Alexis F League, Barkha J Yadav-Samudrala, Ramya Kolagani, Calista A Cline, Ian R Jacobs, Jonathan Manke, Micah J Niphakis, Benjamin F Cravatt, Aron H Lichtman, Bogna M Ignatowska-Jankowska, Sylvia Fittin. A helping HAND: therapeutic potential of MAGL inhibition against HIV-1-associated neuroinflammation. Frontiers in immunology. vol 15. 2024-06-05. PMID:38835765. |
cannabinoid anti-inflammatory effects are well documented, but therapeutic utility of cannabis remains limited due to its psychotropic effects, including alterations within brain regions encoding reward processing and motivation, such as the nucleus accumbens. |
2024-06-05 |
2024-06-07 |
human |
| Young-Jung Kim, Su Jeong Choi, Sa-Ik Hong, Jung-Cheol Park, Youyoung Lee, Shi-Xun Ma, Kwang-Hyun Hur, Young Lee, Kyeong-Man Kim, Hyung Kyu Kim, Hee Young Kim, Seok-Yong Lee, Se-Young Choi, Choon-Gon Jan. The ion channel TRPA1 is a modulator of the cocaine reward circuit in the nucleus accumbens. Molecular psychiatry. 2024-05-31. PMID:38822069. |
the ion channel trpa1 is a modulator of the cocaine reward circuit in the nucleus accumbens. |
2024-05-31 |
2024-06-02 |
mouse |
| Young-Jung Kim, Su Jeong Choi, Sa-Ik Hong, Jung-Cheol Park, Youyoung Lee, Shi-Xun Ma, Kwang-Hyun Hur, Young Lee, Kyeong-Man Kim, Hyung Kyu Kim, Hee Young Kim, Seok-Yong Lee, Se-Young Choi, Choon-Gon Jan. The ion channel TRPA1 is a modulator of the cocaine reward circuit in the nucleus accumbens. Molecular psychiatry. 2024-05-31. PMID:38822069. |
because the connection between pleasure and drug use becomes hard-wired in the nucleus accumbens (nac), which interfaces motivation, effective therapies need to modulate this mesolimbic reward system. |
2024-05-31 |
2024-06-02 |
mouse |
| Devin P Hagarty, Adam Dawoud, Alfonso Brea Guerrero, Kaynas Phillips, Caroline E Strong, Sarah Dollie Jennings, Michelle Crawford, Katherine Martinez, Olivia Csernecky, Samantha K Saland, Mohamed Kabba. Exploring Ketamine's Reinforcement, Cue-Induced Reinstatement, and Nucleus Accumbens cFos Activation in Male and Female Long Evans Rats. Neuropharmacology. 2024-05-26. PMID:38797243. |
neuronal activation was assessed using the protein expression of the immediate early gene cfos in the nucleus accumbens (nac), an important brain area implicated in reward, reinforcement and reinstatement to most drug-related cues. |
2024-05-28 |
2024-05-31 |
rat |
| Devin P Hagarty, Adam Dawoud, Alfonso Brea Guerrero, Kaynas Phillips, Caroline E Strong, Sarah Dollie Jennings, Michelle Crawford, Katherine Martinez, Olivia Csernecky, Samantha K Saland, Mohamed Kabba. Exploring Ketamine's Reinforcement, Cue-Induced Reinstatement, and Nucleus Accumbens cFos Activation in Male and Female Long Evans Rats. Neuropharmacology. 2024-05-26. PMID:38797243. |
neuronal activation was assessed using the protein expression of the immediate early gene cfos in the nucleus accumbens (nac), an important brain area implicated in reward, reinforcement and reinstatement to most drug-related cues. |
2024-05-26 |
2024-05-31 |
rat |
| Sanae Inokuchi-Sakata, Ryo Narita, Yukari Takahashi, Yozo Ishiuji, Akihiko Asahina, Fusao Kat. Region-specific activation in the accumbens nucleus by itch with modified scratch efficacy in mice - a model-free multivariate analysis. Molecular brain. vol 17. issue 1. 2024-05-24. PMID:38783364. |
to address this issue, we targeted the "reward center" of the brain, the nucleus accumbens (nac), in which itch-responsive neurons have been found in rodents. |
2024-05-24 |
2024-05-27 |
mouse |
| Shervin Assari, Payam Sheikhattar. Sex Differences in the Relationship Between Nucleus Accumbens Volume and Youth Tobacco or Marijuana Use Following Stressful Life Events. Journal of mental health & clinical psychology. vol 8. issue 2. 2024-05-18. PMID:38751734. |
these events may influence substance use by altering brain reward systems, especially the nucleus accumbens (nac), which plays a key role in motivated behaviors and reward processing. |
2024-05-18 |
2024-05-27 |
Not clear |