| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yu-Chen Cha. Neural Correlates of Deficits in Humor Appreciation in Gelotophobics. Scientific reports. vol 6. 2018-06-15. PMID:27694969. |
in response to non-hostile jokes, non-gelotophobics showed greater activation in the ventral mcl reward system, which comprises the midbrain, amygdalae, nucleus accumbens, ventral anterior cingulate cortex, and insula. |
2018-06-15 |
2023-08-13 |
Not clear |
| Michael S Cohen, Jesse Rissman, Mariam Hovhannisyan, Alan D Castel, Barbara J Knowlto. Free recall test experience potentiates strategy-driven effects of value on memory. Journal of experimental psychology. Learning, memory, and cognition. vol 43. issue 10. 2018-05-29. PMID:28394160. |
by another mechanism, information paired with value or reward is automatically strengthened in memory via dopaminergic projections from midbrain to hippocampus (shohamy & adcock, 2010). |
2018-05-29 |
2023-08-13 |
human |
| Steven J Simmons, Rose Martorana, Helene Philogene-Khalid, Fionya H Tran, Taylor A Gentile, Xinyan Xu, Shu Su, Scott M Rawls, John W Muscham. Role of hypocretin/orexin receptor blockade on drug-taking and ultrasonic vocalizations (USVs) associated with low-effort self-administration of cathinone-derived 3,4-methylenedioxypyrovalerone (MDPV) in rats. Psychopharmacology. vol 234. issue 21. 2018-05-14. PMID:28786030. |
pharmacological agents that disrupt excitatory transmission onto midbrain da-producing neurons, including hypothalamic hypocretin/orexin (hcrt/ox) receptor antagonists, present attractive targets to aide abstinence maintenance by reducing psychostimulant-associated reward and reinforcement. |
2018-05-14 |
2023-08-13 |
rat |
| Erik Schéle, Christopher Cook, Marie Le May, Tina Bake, Simon M Luckman, Suzanne L Dickso. Central administration of ghrelin induces conditioned avoidance in rodents. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 27. issue 8. 2018-04-18. PMID:28647450. |
given that ghrelin also activates pathways in the midbrain that are important for reward, it remains possible that ghrelin could act as a positive reinforcer and hence, carry a positive-valence signal. |
2018-04-18 |
2023-08-13 |
rat |
| Norihiro Takakuwa, Rikako Kato, Peter Redgrave, Tadashi Is. Emergence of visually-evoked reward expectation signals in dopamine neurons via the superior colliculus in V1 lesioned monkeys. eLife. vol 6. 2018-03-26. PMID:28628005. |
responses of midbrain dopamine (da) neurons reflecting expected reward from sensory cues are critical for reward-based associative learning. |
2018-03-26 |
2023-08-13 |
monkey |
| Peter J Vento, Nathan W Burnham, Courtney S Rowley, Thomas C Jho. Learning From One's Mistakes: A Dual Role for the Rostromedial Tegmental Nucleus in the Encoding and Expression of Punished Reward Seeking. Biological psychiatry. vol 81. issue 12. 2018-03-02. PMID:27931744. |
the recently identified rostromedial tegmental nucleus (rmtg) encodes a wide variety of aversive stimuli and sends robust inhibitory projections to midbrain dopamine neurons, leading to the hypothesis that the rmtg provides a brake to reward signaling in response to aversive costs. |
2018-03-02 |
2023-08-13 |
Not clear |
| Alexander A Nevue, Richard A Felix, Christine V Portfor. Dopaminergic projections of the subparafascicular thalamic nucleus to the auditory brainstem. Hearing research. vol 341. 2018-02-13. PMID:27620513. |
dopamine, which plays a major role in reward and movement, has been shown to alter neural responses in the auditory brainstem and midbrain. |
2018-02-13 |
2023-08-13 |
Not clear |
| Akina Umemoto, Azadeh HajiHosseini, Michael E Yates, Clay B Holroy. Reward-based contextual learning supported by anterior cingulate cortex. Cognitive, affective & behavioral neuroscience. vol 17. issue 3. 2018-02-06. PMID:28236171. |
analysis of the reward positivity, an erp component believed to reflect reward-related signals carried to the acc by the midbrain dopamine system, revealed that the acc is sensitive to differences in the reward values associated with both the casinos and the games inside the casinos, indicating that participants learned the values of the contexts in which rewards were delivered. |
2018-02-06 |
2023-08-13 |
human |
| Ting Li, Xu Chen, Jennifer Mascaro, Ebrahim Haroon, James K Rillin. Intranasal oxytocin, but not vasopressin, augments neural responses to toddlers in human fathers. Hormones and behavior. vol 93. 2018-01-30. PMID:28161387. |
intranasal ot, but not avp, significantly increased the bold fmri response to viewing pictures of own children within the caudate nucleus, a target of midbrain dopamine projections, as well as the dorsal anterior cingulate (dacc) and visual cortex, suggesting that intranasal oxytocin augments activation in brain regions involved in reward, empathy and attention in human fathers. |
2018-01-30 |
2023-08-13 |
human |
| S Hong, O Hikosak. Pedunculopontine tegmental nucleus neurons provide reward, sensorimotor, and alerting signals to midbrain dopamine neurons. Neuroscience. vol 282. 2018-01-26. PMID:25058502. |
pedunculopontine tegmental nucleus neurons provide reward, sensorimotor, and alerting signals to midbrain dopamine neurons. |
2018-01-26 |
2023-08-13 |
monkey |
| Wolfram Schult. Reward functions of the basal ganglia. Journal of neural transmission (Vienna, Austria : 1996). vol 123. issue 7. 2018-01-23. PMID:26838982. |
this review describes the reward functions of three brain structures that are major components of the basal ganglia or are closely associated with the basal ganglia, namely midbrain dopamine neurons, pedunculopontine nucleus, and striatum (caudate nucleus, putamen, nucleus accumbens). |
2018-01-23 |
2023-08-13 |
Not clear |
| Iris M Balodis, Hedy Kober, Patrick D Worhunsky, Michael C Stevens, Godfrey D Pearlson, Kathleen M Carroll, Marc N Potenz. Neurofunctional Reward Processing Changes in Cocaine Dependence During Recovery. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 8. 2018-01-15. PMID:26792441. |
relative to pretreatment, at posttreatment cd participants demonstrated increased anticipatory reward activity in the midbrain, thalamus, and precuneus (pfwe<0.05). |
2018-01-15 |
2023-08-13 |
human |
| Yong Sang Jo, Sheri J Y Mizumor. Prefrontal Regulation of Neuronal Activity in the Ventral Tegmental Area. Cerebral cortex (New York, N.Y. : 1991). vol 26. issue 10. 2018-01-10. PMID:26400913. |
growing evidence indicates that midbrain dopamine (da) cells integrate reward expectancy-related information from the prefrontal cortex to properly compute errors in reward prediction. |
2018-01-10 |
2023-08-13 |
rat |
| Rahul Pandit, Azar Omrani, Mieneke C M Luijendijk, Véronne A J de Vrind, Andrea J Van Rozen, Ralph J A Oude Ophuis, Keith Garner, Imre Kallo, Alexander Ghanem, Zsolt Liposits, Karl-Klaus Conzelmann, Louk J M J Vanderschuren, Susanne E la Fleur, Roger A H Ada. Melanocortin 3 Receptor Signaling in Midbrain Dopamine Neurons Increases the Motivation for Food Reward. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 9. 2018-01-09. PMID:26852738. |
melanocortin 3 receptor signaling in midbrain dopamine neurons increases the motivation for food reward. |
2018-01-09 |
2023-08-13 |
rat |
| Matthew Brodsky, Alec W Gibson, Denis Smirnov, Sunila G Nair, John F Neumaie. Striatal 5-HT6 Receptors Regulate Cocaine Reinforcement in a Pathway-Selective Manner. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 9. 2018-01-09. PMID:27032690. |
the nucleus accumbens (nac) in the ventral striatum integrates many neurochemical inputs including dopamine and serotonin projections from midbrain nuclei to modulate drug reward. |
2018-01-09 |
2023-08-13 |
rat |
| Maggie C Evans, Greg M Anderso. Dopamine Neuron-Restricted Leptin Receptor Signaling Reduces Some Aspects of Food Reward but Exacerbates the Obesity of Leptin Receptor-Deficient Male Mice. Endocrinology. vol 158. issue 12. 2017-12-18. PMID:28938472. |
midbrain dopamine neurons regulate the reward value of food, and direct leptin administration to the midbrain reduces food intake. |
2017-12-18 |
2023-08-13 |
mouse |
| Sarah X Luo, Leah Timbang, Jae-Ick Kim, Yulei Shang, Kadellyn Sandoval, Amy A Tang, Jennifer L Whistler, Jun B Ding, Eric J Huan. TGF-β Signaling in Dopaminergic Neurons Regulates Dendritic Growth, Excitatory-Inhibitory Synaptic Balance, and Reversal Learning. Cell reports. vol 17. issue 12. 2017-11-20. PMID:28009292. |
neural circuits involving midbrain dopaminergic (da) neurons regulate reward and goal-directed behaviors. |
2017-11-20 |
2023-08-13 |
mouse |
| Francesco Rigoli, Benjamin Chew, Peter Dayan, Raymond J Dola. The Dopaminergic Midbrain Mediates an Effect of Average Reward on Pavlovian Vigor. Journal of cognitive neuroscience. vol 28. issue 9. 2017-11-17. PMID:27082045. |
the dopaminergic midbrain mediates an effect of average reward on pavlovian vigor. |
2017-11-17 |
2023-08-13 |
human |
| Francesco Rigoli, Benjamin Chew, Peter Dayan, Raymond J Dola. The Dopaminergic Midbrain Mediates an Effect of Average Reward on Pavlovian Vigor. Journal of cognitive neuroscience. vol 28. issue 9. 2017-11-17. PMID:27082045. |
greater average reward was associated with enhanced activity in dopaminergic midbrain to a degree that correlated with the relationship between average reward and pressing vigor. |
2017-11-17 |
2023-08-13 |
human |
| Francesco Rigoli, Benjamin Chew, Peter Dayan, Raymond J Dola. The Dopaminergic Midbrain Mediates an Effect of Average Reward on Pavlovian Vigor. Journal of cognitive neuroscience. vol 28. issue 9. 2017-11-17. PMID:27082045. |
these findings highlight a crucial role for dopaminergic midbrain in representing aspects of average reward and motivational vigor. |
2017-11-17 |
2023-08-13 |
human |