| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Philip R Corlett, Jessica A Mollick, Hedy Kobe. Meta-analysis of human prediction error for incentives, perception, cognition, and action. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-01-12. PMID:35017672. |
across 264 pe studies that have focused on reward, punishment, action, cognition, and perception, consistent with domain-general theoretical models of prediction error we found midbrain pe signals during cognitive and reward learning tasks, and an insula pe signal for perceptual, social, cognitive, and reward prediction errors. |
2022-01-12 |
2023-08-13 |
human |
| Isao Nagata, Mika Sasaki, Tomoyuki Miyazaki, Kensuke Saeki, Ken-Ichi Ogawa, Yoshinori Kamiy. Subanesthetic Dose of Propofol Activates the Reward System in Rats. Anesthesia and analgesia. 2021-12-27. PMID:34958308. |
activation of the dopaminergic circuits of the midbrain reward system, including the ventral tegmental area (vta) and nac, plays a crucial role in addiction. |
2021-12-27 |
2023-08-13 |
rat |
| Hannah N Carlson, Brooke A Christensen, Wayne E Prat. Stimulation of mu opioid, but not GABAergic, receptors of the lateral habenula alters free feeding in rats. Neuroscience letters. 2021-12-26. PMID:34954115. |
the purpose of the present study was to assess the lateral habenula as a candidate region for such a mechanism, due to its connectivity to midbrain reward circuitry, sensitivity to metabolic signaling, and pronounced role in drug-related motivated behaviors. |
2021-12-26 |
2023-08-13 |
human |
| Mario Widmer, Jeremia P O Held, Frieder Wittmann, Belen Valladares, Olivier Lambercy, Christian Sturzenegger, Antonella Palla, Kai Lutz, Andreas R Luf. Reward During Arm Training Improves Impairment and Activity After Stroke: A Randomized Controlled Trial. Neurorehabilitation and neural repair. 2021-12-23. PMID:34937456. |
these mechanisms depend on dopaminergic projections from midbrain that may encode reward information. |
2021-12-23 |
2023-08-13 |
Not clear |
| Manal T Hussein, Abdelraheim Attaai, Gamal Kamel, Doaa M Mokhta. Spatiotemporal expression of sonic hedgehog signalling molecules in the embryonic mesencephalic dopaminergic neurons. Gene expression patterns : GEP. vol 42. 2021-12-09. PMID:34767969. |
midbrain dopaminergic neurons (mda) play an important role in controlling the voluntary motor movement, reward, and emotion-based behaviour. |
2021-12-09 |
2023-08-13 |
Not clear |
| Nathan D Winters, Gaurav Bedse, Anastasia A Astafyev, Toni A Patrick, Megan Altemus, Amanda J Morgan, Snigdha Mukerjee, Keenan D Johnson, Vikrant R Mahajan, Md Jashim Uddin, Philip J Kingsley, Samuel W Centanni, Cody A Siciliano, David C Samuels, Lawrence J Marnett, Danny G Winder, Sachin Pate. Targeting diacylglycerol lipase reduces alcohol consumption in preclinical models. The Journal of clinical investigation. 2021-12-03. PMID:34292886. |
lastly, dagl inhibition also prevented ethanol-induced suppression of gabaergic transmission onto midbrain dopamine neurons, providing mechanistic insight into how dagl inhibition could affect alcohol reward. |
2021-12-03 |
2023-08-13 |
mouse |
| Lindsey N Friend, Bridget Wu, Jeffrey G Edward. Acute cocaine exposure occludes long-term depression in ventral tegmental area GABA neurons. Neurochemistry international. vol 145. 2021-11-18. PMID:33617930. |
the ventral tegmental area (vta) in the midbrain is essential in incentive salience of reward behavior. |
2021-11-18 |
2023-08-13 |
mouse |
| Feng He, Pei Zhang, Qian Zhang, Guangjian Qi, Hongwei Cai, Tongxia Li, Ming Li, Jiazhen Lu, Jiaen Lin, Jie Ming, Bo Tia. Dopaminergic Projection from Ventral Tegmental Area to Substantia Nigra Pars Reticulata Mediates Chronic Social Defeat Stress-Induced Hypolocomotion. Molecular neurobiology. vol 58. issue 11. 2021-11-18. PMID:34382160. |
in mdd, the midbrain ventral tegmental area (vta) dopamine (da) neurons are closely related to regulate the information processing of reward, motivation, cognition, and aversion. |
2021-11-18 |
2023-08-13 |
mouse |
| Shamseddin Ahmadi, Mohammad Zobeiri, Shiva Mohammadi Talvar, Kayvan Masoudi, Amir Khanizad, Shima Fotouhi, Steven Bradbur. Differential expression of H19, BC1, MIAT1, and MALAT1 long non-coding RNAs within key brain reward regions after repeated morphine treatment. Behavioural brain research. vol 414. 2021-11-04. PMID:34302875. |
we conclude that alterations in the expression of these lncrnas in the brain reward regions especially in the midbrain, striatum and hypothalamus may have critical roles in the development of morphine dependence and tolerance, which need to be considered in future researches. |
2021-11-04 |
2023-08-13 |
rat |
| Dong-Hee Kim, Bo-Ryoung Choi, Yong-Jae Jeon, Yoon-Sun Jang, Jung-Soo Ha. Engagement of lateral habenula in the extinction of the appetitive conditioned responses. Behavioural brain research. vol 415. 2021-11-04. PMID:34389424. |
midbrain dopamine neurons are activated by presenting a reward or predictable reward cue, whereas the cue signaling the absence of reward activates the lateral habenula (lhb) neurons. |
2021-11-04 |
2023-08-13 |
rat |
| Andrea N Belovich, Jenny I Aguilar, Samuel J Mabry, Mary H Cheng, Daniele Zanella, Peter J Hamilton, Daniel J Stanislowski, Aparna Shekar, James D Foster, Ivet Bahar, Heinrich J G Matthies, Aurelio Gall. A network of phosphatidylinositol (4,5)-bisphosphate (PIP Molecular psychiatry. vol 26. issue 8. 2021-11-02. PMID:31796894. |
numerous human pet-fmri studies establish a link between midbrain dopamine (da) release, da transporter (dat) availability, and reward responses. |
2021-11-02 |
2023-08-13 |
human |
| b' Marc Fakhoury, Giovanni Hernandez, Daniel L\\xc3\\xa9vesque, Pierre-Paul Rompr\\xc3\\xa. Modulation of brain stimulation reward and locomotor activity by ionotropic glutamate receptors of the tail of the ventral tegmental area. Behavioural brain research. vol 393. 2021-10-25. PMID:32593543.' |
in light of previous evidence implicating glutamate transmission in the regulation of midbrain da neuronal activity, we first assessed the impact of intra-tvta microinjection of nbqx (0.8 nmol/side) and pppa (0.825 nmol/side), respectively ampa and nmda receptor antagonists, on reward induced by intracranial self-stimulation (icss) and on locomotor activity. |
2021-10-25 |
2023-08-13 |
Not clear |
| Ruth Hanssen, Alina Chloé Kretschmer, Lionel Rigoux, Kerstin Albus, Sharmili Edwin Thanarajah, Tamara Sitnikow, Corina Melzer, Oliver A Cornely, Jens C Brüning, Marc Tittgemeye. GLP-1 and hunger modulate incentive motivation depending on insulin sensitivity in humans. Molecular metabolism. vol 45. 2021-10-25. PMID:33453418. |
incentive motivation refers to the processes that translate an expected reward into the effort spent to obtain the reward; the magnitude and probability of a reward involved in prompting motivated behaviour are encoded by the dopaminergic (da) midbrain and its mesoaccumbens da projections. |
2021-10-25 |
2023-08-13 |
Not clear |
| Mikhail U Inyushin, Francisco Arencibia-Albite, Angel de la Cruz, Rafael Vázquez-Torres, Katiria Colon, Priscila Sanabria, Carlos A Jiménez-River. New method to visualize neurons with DAT in slices of rat VTA using fluorescent substrate for DAT, ASP+ Journal of neuroscience and neuroengineering. vol 2. issue 2. 2021-10-21. PMID:24052926. |
new method to visualize neurons with dat in slices of rat vta using fluorescent substrate for dat, asp+ the ventral tegmental area (vta), and in particular dopamine (da) neurons in this region of midbrain, has been shown to play an important role in motivation (goal-directed behavior), reward, and drug addiction. |
2021-10-21 |
2023-08-12 |
rat |
| Bernadete Negrelli, José Augusto Pochapski, Cyrus Antonio Villas-Boas, Letícia Ferreira Jessen, Mayra Aline Lopes Teixeira, Claudio Da Cunh. Evidence that haloperidol impairs learning and motivation scores in a probabilistic task by reducing the reward expectation. Behavioural brain research. vol 395. 2021-10-13. PMID:32810468. |
activation of midbrain dopamine neurons in response to positive prediction errors and reward predictive cues is proposed to "energize" reward seeking behaviors and approach responses to places where the reward is expected. |
2021-10-13 |
2023-08-13 |
rat |
| James D Howard, Thorsten Kahn. To be specific: The role of orbitofrontal cortex in signaling reward identity. Behavioral neuroscience. vol 135. issue 2. 2021-09-20. PMID:33734730. |
moreover, we summarize recent findings suggesting that specific reward expectations in ofc are learned and updated by means of identity errors in the dopaminergic midbrain. |
2021-09-20 |
2023-08-13 |
Not clear |
| G Elliott Wimmer, Russell A Poldrac. Reward learning and working memory: Effects of massed versus spaced training and post-learning delay period. Memory & cognition. 2021-09-14. PMID:34519968. |
neuroscience research has illuminated the mechanisms supporting learning from reward feedback, demonstrating a critical role for the striatum and midbrain dopamine system. |
2021-09-14 |
2023-08-13 |
Not clear |
| Adam S Lowet, Qiao Zheng, Sara Matias, Jan Drugowitsch, Naoshige Uchid. Distributional Reinforcement Learning in the Brain. Trends in neurosciences. vol 43. issue 12. 2021-08-18. PMID:33092893. |
classical studies have demonstrated an impressive correspondence between the firing of dopamine neurons in the mammalian midbrain and the reward prediction errors of reinforcement learning algorithms, which express the difference between actual reward and predicted mean reward. |
2021-08-18 |
2023-08-13 |
Not clear |
| Rui Lin, Jingwen Liang, Minmin Lu. The Raphe Dopamine System: Roles in Salience Encoding, Memory Expression, and Addiction. Trends in neurosciences. vol 44. issue 5. 2021-08-18. PMID:33568331. |
while the vta da population is known to play important roles in reward processing, emerging evidence now supports the view that drn da neurons are a specialized midbrain da subsystem that performs distinct functions in parallel to the vta da population. |
2021-08-18 |
2023-08-13 |
mouse |
| Anja Richter, Fabian Reinhard, Bernd Kraemer, Oliver Grube. A high-resolution fMRI approach to characterize functionally distinct neural pathways within dopaminergic midbrain and nucleus accumbens during reward and salience processing. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 36. 2021-08-10. PMID:32546416. |
a high-resolution fmri approach to characterize functionally distinct neural pathways within dopaminergic midbrain and nucleus accumbens during reward and salience processing. |
2021-08-10 |
2023-08-13 |
human |