| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Clay B Holroyd, Travis E Baker, Kimberly A Kerns, Ulrich Mülle. Electrophysiological evidence of atypical motivation and reward processing in children with attention-deficit hyperactivity disorder. Neuropsychologia. vol 46. issue 8. 2008-08-26. PMID:18367216. |
this result indicates that children with adhd are unusually sensitive to the salience of reward and suggests that such sensitivity may be mediated in part by the midbrain dopamine system. |
2008-08-26 |
2023-08-12 |
Not clear |
| Jordi Riba, Ulrike M Krämer, Marcus Heldmann, Sylvia Richter, Thomas F Münt. Dopamine agonist increases risk taking but blunts reward-related brain activity. PloS one. vol 3. issue 6. 2008-08-20. PMID:18575579. |
moreover, we demonstrate decreased activation in the rostral basal ganglia and midbrain, key structures of the reward system, following unexpected high gains and therefore propose that pathological gambling in pd results from the need to seek higher rewards to overcome the blunted response in this system. |
2008-08-20 |
2023-08-12 |
human |
| J G P Ferreira, F Del-Fava, R H Hasue, S J Shammah-Lagnad. Organization of ventral tegmental area projections to the ventral tegmental area-nigral complex in the rat. Neuroscience. vol 153. issue 1. 2008-08-18. PMID:18358616. |
based on its striatal output, it has been subdivided in a caudomedial part which targets the ventromedial striatum, and a lateral part which targets the ventrolateral striatum [ikemoto s (2007) dopamine reward circuitry: two projection systems from the ventral midbrain to the nucleus accumbens-olfactory tubercle complex. |
2008-08-18 |
2023-08-12 |
rat |
| R G Nair-Roberts, S D Chatelain-Badie, E Benson, H White-Cooper, J P Bolam, M A Ungles. Stereological estimates of dopaminergic, GABAergic and glutamatergic neurons in the ventral tegmental area, substantia nigra and retrorubral field in the rat. Neuroscience. vol 152. issue 4. 2008-08-07. PMID:18355970. |
midbrain dopamine neurons in the ventral tegmental area, substantia nigra and retrorubral field play key roles in reward processing, learning and memory, and movement. |
2008-08-07 |
2023-08-12 |
rat |
| Heather Walsh, Anitha P Govind, Ryan Mastro, J C Hoda, Daniel Bertrand, Yolanda Vallejo, William N Gree. Up-regulation of nicotinic receptors by nicotine varies with receptor subtype. The Journal of biological chemistry. vol 283. issue 10. 2008-05-30. PMID:18174175. |
recent evidence suggests that in addition to alpha4beta2 and alpha3-containing nicotinic receptors, alpha6-containing receptors are present in midbrain dopaminergic neurons and involved in the nicotine reward pathway. |
2008-05-30 |
2023-08-12 |
Not clear |
| G K Murray, P R Corlett, L Clark, M Pessiglione, A D Blackwell, G Honey, P B Jones, E T Bullmore, T W Robbins, P C Fletche. Substantia nigra/ventral tegmental reward prediction error disruption in psychosis. Molecular psychiatry. vol 13. issue 3. 2008-04-17. PMID:17684497. |
to examine a link between psychotic experience, reward learning and dysfunction of the dopaminergic midbrain and associated target regions, we asked a group of first episode psychosis patients suffering from active positive symptoms and a group of healthy control participants to perform an instrumental reward conditioning experiment. |
2008-04-17 |
2023-08-12 |
human |
| Qian Gao, Tamas L Horvat. Neuronal control of energy homeostasis. FEBS letters. vol 582. issue 1. 2008-03-12. PMID:18061579. |
various hypothalamic neuronal circuits (which include the hypothalamic melanocortin, midbrain dopamine reward and caudal brainstem autonomic feeding systems) control energy intake and expenditure to maintain body weight within a narrow range for long periods of a life span. |
2008-03-12 |
2023-08-12 |
Not clear |
| Satoshi Ikemot. Dopamine reward circuitry: two projection systems from the ventral midbrain to the nucleus accumbens-olfactory tubercle complex. Brain research reviews. vol 56. issue 1. 2008-02-26. PMID:17574681. |
dopamine reward circuitry: two projection systems from the ventral midbrain to the nucleus accumbens-olfactory tubercle complex. |
2008-02-26 |
2023-08-12 |
rat |
| Satoshi Ikemot. Dopamine reward circuitry: two projection systems from the ventral midbrain to the nucleus accumbens-olfactory tubercle complex. Brain research reviews. vol 56. issue 1. 2008-02-26. PMID:17574681. |
a review of the literature suggests that (1) the midbrain has corresponding zones for the accumbens core and medial shell; (2) the striatal portion of the olfactory tubercle is a ventral extension of the nucleus accumbens shell; and (3) a model of two dopamine projection systems from the ventral midbrain to the ventral striatum is useful for understanding reward function. |
2008-02-26 |
2023-08-12 |
rat |
| Clemens Gruber, Anja Kahl, Lydia Lebenheim, Alexander Kowski, Anja Dittgen, Rüdiger W Ve. Dopaminergic projections from the VTA substantially contribute to the mesohabenular pathway in the rat. Neuroscience letters. vol 427. issue 3. 2008-02-25. PMID:17949902. |
recent evidence suggests that the lateral habenular complex (lhb) is a source of negative reward signals in midbrain dopaminergic neurons. |
2008-02-25 |
2023-08-12 |
rat |
| John P O'Dohert. Lights, camembert, action! The role of human orbitofrontal cortex in encoding stimuli, rewards, and choices. Annals of the New York Academy of Sciences. vol 1121. 2008-02-04. PMID:17872386. |
it will be argued that human orbitofrontal cortex is involved in a number of distinct functions: signaling the affective value of stimuli as they are perceived, encoding expectations of future reward, and updating these expectations, either by making use of prediction error signals generated in the midbrain, or by using knowledge of the rules or structure of the decision problem. |
2008-02-04 |
2023-08-12 |
human |
| Hannah M Bayer, Brian Lau, Paul W Glimche. Statistics of midbrain dopamine neuron spike trains in the awake primate. Journal of neurophysiology. vol 98. issue 3. 2008-01-07. PMID:17615124. |
work in behaving primates indicates that midbrain dopamine neurons encode a prediction error, the difference between an obtained reward and the reward expected. |
2008-01-07 |
2023-08-12 |
rat |
| Monika Cs Horvath, Gabor G Kovacs, Viktor Kovari, Katalin Majtenyi, Yasmin L Hurd, Eva Kelle. Heroin abuse is characterized by discrete mesolimbic dopamine and opioid abnormalities and exaggerated nuclear receptor-related 1 transcriptional decline with age. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 49. 2007-12-27. PMID:18057194. |
altogether the current findings provide direct neurobiological evidence that midbrain reward circuits have the most prominent da and opioid impairments in human heroin abusers and that abnormal nurr1 transcription with opiate use may exacerbate limbic dysfunction with age. |
2007-12-27 |
2023-08-12 |
human |
| Birgit Völlm, Paul Richardson, Shane McKie, Rebecca Elliott, Mairead Dolan, Bill Deaki. Neuronal correlates of reward and loss in Cluster B personality disorders: a functional magnetic resonance imaging study. Psychiatry research. vol 156. issue 2. 2007-12-21. PMID:17920821. |
areas implicated in reward include ventral striatum, dopaminergic midbrain, amygdala and orbitofrontal cortex. |
2007-12-21 |
2023-08-12 |
human |
| Bianca C Wittmann, Nico Bunzeck, Raymond J Dolan, Emrah Düze. Anticipation of novelty recruits reward system and hippocampus while promoting recollection. NeuroImage. vol 38. issue 1. 2007-11-26. PMID:17764976. |
the dopaminergic midbrain, which comprises the substantia nigra and ventral tegmental area (sn/vta), plays a central role in reward processing. |
2007-11-26 |
2023-08-12 |
human |
| Richard D Palmite. Is dopamine a physiologically relevant mediator of feeding behavior? Trends in neurosciences. vol 30. issue 8. 2007-11-06. PMID:17604133. |
midbrain dopamine neurons have long been implicated in mediating reward behavior and the motivational aspects of feeding behavior. |
2007-11-06 |
2023-08-12 |
Not clear |
| Björn H Schott, Ludwig Niehaus, Bianca C Wittmann, Hartmut Schütze, Constanze I Seidenbecher, Hans-Jochen Heinze, Emrah Düze. Ageing and early-stage Parkinson's disease affect separable neural mechanisms of mesolimbic reward processing. Brain : a journal of neurology. vol 130. issue Pt 9. 2007-11-01. PMID:17626038. |
young adults showed the well-replicated pattern of midbrain and ventral striatal activation for stimuli that predicted monetary reward when compared with stimuli that predicted neutral feedback. |
2007-11-01 |
2023-08-12 |
human |
| Björn H Schott, Ludwig Niehaus, Bianca C Wittmann, Hartmut Schütze, Constanze I Seidenbecher, Hans-Jochen Heinze, Emrah Düze. Ageing and early-stage Parkinson's disease affect separable neural mechanisms of mesolimbic reward processing. Brain : a journal of neurology. vol 130. issue Pt 9. 2007-11-01. PMID:17626038. |
parkinson's disease patients additionally displayed a relatively increased response of the anterior cingulate during reward feedback processing and diminished functional connectivity of the midbrain and ventral striatum. |
2007-11-01 |
2023-08-12 |
human |
| Raad Nashmi, Cheng Xiao, Purnima Deshpande, Sheri McKinney, Sharon R Grady, Paul Whiteaker, Qi Huang, Tristan McClure-Begley, Jon M Lindstrom, Cesar Labarca, Allan C Collins, Michael J Marks, Henry A Leste. Chronic nicotine cell specifically upregulates functional alpha 4* nicotinic receptors: basis for both tolerance in midbrain and enhanced long-term potentiation in perforant path. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 31. 2007-08-28. PMID:17670967. |
although the midbrain dopaminergic system dominates reward pathways, chronic nicotine does not change alpha4* receptor levels in dopaminergic neurons of ventral tegmental area (vta) or substantia nigra pars compacta. |
2007-08-28 |
2023-08-12 |
mouse |
| Alice Blackshear, Mihoko Yamamoto, Brenda J Anderson, Philip V Holmes, Linda Lundström, Ulo Langel, John K Robinso. Intracerebroventricular administration of galanin or galanin receptor subtype 1 agonist M617 induces c-Fos activation in central amygdala and dorsomedial hypothalamus. Peptides. vol 28. issue 5. 2007-08-24. PMID:17337094. |
the neuropeptide galanin and galanin receptors are widespread throughout cortical, limbic and midbrain areas implicated in reward, learning/memory, pain, drinking and feeding. |
2007-08-24 |
2023-08-12 |
rat |