| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ben Yang, Lauren B Geary, Yong-Chao M. In ovo electroporation in chick midbrain for studying gene function in dopaminergic neuron development. Journal of visualized experiments : JoVE. issue 66. 2012-10-22. PMID:22895156. |
dopaminergic neurons located in the ventral midbrain control movement, emotional behavior, and reward mechanisms. |
2012-10-22 |
2023-08-12 |
human |
| Bettina Studer, Annemieke M Apergis-Schoute, Trevor W Robbins, Luke Clar. What are the Odds? The Neural Correlates of Active Choice during Gambling. Frontiers in neuroscience. vol 6. 2012-10-02. PMID:22529770. |
our results highlight the impact of volitional choice upon gambling-related brain activity: neural activity in a distributed network - including key structures of the reward circuitry (midbrain, striatum) - was higher during active compared to computer-dictated bet selection. |
2012-10-02 |
2023-08-12 |
human |
| Nico Bunzeck, Christian F Doeller, Ray J Dolan, Emrah Duze. Contextual interaction between novelty and reward processing within the mesolimbic system. Human brain mapping. vol 33. issue 6. 2012-09-17. PMID:21520353. |
medial temporal lobe (mtl) dependent long-term memory for novel events is modulated by a circuitry that also responds to reward and includes the ventral striatum, dopaminergic midbrain, and medial orbitofrontal cortex (mofc). |
2012-09-17 |
2023-08-12 |
Not clear |
| Erin C Dowd, Deanna M Barc. Pavlovian reward prediction and receipt in schizophrenia: relationship to anhedonia. PloS one. vol 7. issue 5. 2012-09-10. PMID:22574121. |
at the time of receipt, robust responses to receipt of reward vs. nonreward were seen in striatum, midbrain, and frontal cortex in both groups. |
2012-09-10 |
2023-08-12 |
human |
| Julia P Dunn, Robert M Kessler, Irene D Feurer, Nora D Volkow, Bruce W Patterson, Mohammad S Ansari, Rui Li, Pamela Marks-Shulman, Naji N Abumra. Relationship of dopamine type 2 receptor binding potential with fasting neuroendocrine hormones and insulin sensitivity in human obesity. Diabetes care. vol 35. issue 5. 2012-08-09. PMID:22432117. |
midbrain dopamine (da) neurons, which are involved with reward and motivation, are modulated by hormones that regulate food intake (insulin, leptin, and acyl ghrelin [ag]). |
2012-08-09 |
2023-08-12 |
human |
| Xuefeng Shen, Xiaoguo Ruan, Hua Zha. Stimulation of midbrain dopaminergic structures modifies firing rates of rat lateral habenula neurons. PloS one. vol 7. issue 4. 2012-07-27. PMID:22485164. |
ventral tegmental area (vta) and substantia nigra pars compacta (snpc) are midbrain structures known to be involved in mediating reward in rodents. |
2012-07-27 |
2023-08-12 |
rat |
| Xuefeng Shen, Xiaoguo Ruan, Hua Zha. Stimulation of midbrain dopaminergic structures modifies firing rates of rat lateral habenula neurons. PloS one. vol 7. issue 4. 2012-07-27. PMID:22485164. |
lateral habenula (lhb) is considered as a negative reward source and it is reported that stimulation of the lhb rapidly induces inhibition of firing in midbrain dopamine neurons. |
2012-07-27 |
2023-08-12 |
rat |
| Xuefeng Shen, Xiaoguo Ruan, Hua Zha. Stimulation of midbrain dopaminergic structures modifies firing rates of rat lateral habenula neurons. PloS one. vol 7. issue 4. 2012-07-27. PMID:22485164. |
we conclude that lhb pain-activated neurons can receive diverse reward-related signals originating from midbrain dopaminergic structures, and thus participate in the regulation of the brain reward system via both positive and negative feedback mechanisms. |
2012-07-27 |
2023-08-12 |
rat |
| Hiromasa Takemura, Kazuyuki Samejima, Rufin Vogels, Masamichi Sakagami, Jiro Okud. Stimulus-dependent adjustment of reward prediction error in the midbrain. PloS one. vol 6. issue 12. 2012-07-20. PMID:22164273. |
previous reports have described that neural activities in midbrain dopamine areas are sensitive to unexpected reward delivery and omission. |
2012-07-20 |
2023-08-12 |
human |
| Hiromasa Takemura, Kazuyuki Samejima, Rufin Vogels, Masamichi Sakagami, Jiro Okud. Stimulus-dependent adjustment of reward prediction error in the midbrain. PloS one. vol 6. issue 12. 2012-07-20. PMID:22164273. |
moreover, results show that the difference in correlation between the two models was significant from the first session of the experiment, suggesting that the reward computation in the midbrain was modulated based on stimulus discriminability before learning a new contingency between perceptually ambiguous stimuli and a reward. |
2012-07-20 |
2023-08-12 |
human |
| Krishna P Miyapuram, Philippe N Tobler, Lucy Gregorios-Pippas, Wolfram Schult. BOLD responses in reward regions to hypothetical and imaginary monetary rewards. NeuroImage. vol 59. issue 2. 2012-04-17. PMID:21985912. |
activations to reward predictive stimuli occurred in reward regions, namely the medial orbitofrontal cortex and midbrain. |
2012-04-17 |
2023-08-12 |
human |
| Holden D Brown, James E McCutcheon, Jackson J Cone, Michael E Ragozzino, Mitchell F Roitma. Primary food reward and reward-predictive stimuli evoke different patterns of phasic dopamine signaling throughout the striatum. The European journal of neuroscience. vol 34. issue 12. 2012-04-04. PMID:22122410. |
unpredicted reward and reward-predictive cues evoke phasic increases in the firing rate of the majority of midbrain dopamine neurons--results that predict uniformly broadcast increases in dopamine concentration throughout the striatum. |
2012-04-04 |
2023-08-12 |
rat |
| Holden D Brown, James E McCutcheon, Jackson J Cone, Michael E Ragozzino, Mitchell F Roitma. Primary food reward and reward-predictive stimuli evoke different patterns of phasic dopamine signaling throughout the striatum. The European journal of neuroscience. vol 34. issue 12. 2012-04-04. PMID:22122410. |
unlike the responses of midbrain dopamine neurons, unpredicted food reward and reward-predictive cues evoked a phasic increase in dopamine that was subregion specific. |
2012-04-04 |
2023-08-12 |
rat |
| N D Volkow, G-J Wang, J H Newcorn, S H Kollins, T L Wigal, F Telang, J S Fowler, R Z Goldstein, N Klein, J Logan, C Wong, J M Swanso. Motivation deficit in ADHD is associated with dysfunction of the dopamine reward pathway. Molecular psychiatry. vol 16. issue 11. 2012-03-05. PMID:20856250. |
to evaluate this hypothesis, we performed secondary analyses to assess the correlation between the pet measures of dopamine d2/d3 receptor and dopamine transporter availability (obtained with [(11)c]raclopride and [(11)c]cocaine, respectively) in the dopamine reward pathway (midbrain and nucleus accumbens) and a surrogate measure of trait motivation (assessed using the achievement scale on the multidimensional personality questionnaire or mpq) in 45 adhd participants and 41 controls. |
2012-03-05 |
2023-08-12 |
human |
| Masayuki Matsumoto, Okihide Hikosak. Electrical stimulation of the primate lateral habenula suppresses saccadic eye movement through a learning mechanism. PloS one. vol 6. issue 10. 2012-02-28. PMID:22039537. |
neurons in the lhb are excited by unpleasant events such as reward omission and aversive stimuli, and transmit these signals to midbrain dopamine neurons which are involved in learning and motivation. |
2012-02-28 |
2023-08-12 |
monkey |
| C D Fiorill. Transient activation of midbrain dopamine neurons by reward risk. Neuroscience. vol 197. 2012-02-27. PMID:21963352. |
transient activation of midbrain dopamine neurons by reward risk. |
2012-02-27 |
2023-08-12 |
monkey |
| C D Fiorill. Transient activation of midbrain dopamine neurons by reward risk. Neuroscience. vol 197. 2012-02-27. PMID:21963352. |
dopamine neurons of the ventral midbrain are activated transiently following stimuli that predict future reward. |
2012-02-27 |
2023-08-12 |
monkey |
| Andrew D Lawrence, Ines K Goerendt, David J Brook. Apathy blunts neural response to money in Parkinson's disease. Social neuroscience. vol 6. issue 5-6. 2012-02-24. PMID:21400357. |
we found that apathy was associated with a blunted response to money in the ventromedial prefrontal cortex, amygdala, striatum, and midbrain, all part of a distributed neural circuit integral to the representation of the reward value of stimuli and actions, and the influence of reward cues on behavior. |
2012-02-24 |
2023-08-12 |
human |
| Arnaud L Lalive, Uwe Rudolph, Christian Lüscher, Kelly R Ta. Is there a way to curb benzodiazepine addiction? Swiss medical weekly. vol 141. 2012-02-21. PMID:22012428. |
these results have identified the mechanisms underlying the activation of midbrain dopamine neurons by benzodiazepines, and how these drugs can hijack the mesocorticolimbic reward system. |
2012-02-21 |
2023-08-12 |
Not clear |
| R L Miller, M K Stein, A D Loew. Serotonergic inputs to FoxP2 neurons of the pre-locus coeruleus and parabrachial nuclei that project to the ventral tegmental area. Neuroscience. vol 193. 2012-01-18. PMID:21784133. |
they send extensive projections to the midbrain and forebrain, including a strong projection to the ventral tegmental area (vta)-a reward processing site. |
2012-01-18 |
2023-08-12 |
rat |