| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anthony S Rauhut, Isaac J Zentner, Stacey K Mardekian, Jason B Tanenbau. Wistar Kyoto and Wistar rats differ in the affective and locomotor effects of nicotine. Physiology & behavior. vol 93. issue 1-2. 2008-04-22. PMID:17889041. |
anhedonia is a characteristic of clinical depression and has been associated with dysfunction of the mesolimbic dopaminergic system, a system also involved in mediating nicotine reward. |
2008-04-22 |
2023-08-12 |
rat |
| G K Murray, P R Corlett, L Clark, M Pessiglione, A D Blackwell, G Honey, P B Jones, E T Bullmore, T W Robbins, P C Fletche. Substantia nigra/ventral tegmental reward prediction error disruption in psychosis. Molecular psychiatry. vol 13. issue 3. 2008-04-17. PMID:17684497. |
to examine a link between psychotic experience, reward learning and dysfunction of the dopaminergic midbrain and associated target regions, we asked a group of first episode psychosis patients suffering from active positive symptoms and a group of healthy control participants to perform an instrumental reward conditioning experiment. |
2008-04-17 |
2023-08-12 |
human |
| Mariana Leriche, Antonieta Cote-Vélez, Milagros Ménde. Presence of pro-opiomelanocortin mRNA in the rat medial prefrontal cortex, nucleus accumbens and ventral tegmental area: studies by RT-PCR and in situ hybridization techniques. Neuropeptides. vol 41. issue 6. 2008-04-14. PMID:17980426. |
however, pomc mrna has not been detected in regions of the dopaminergic mesocorticolimbic system, which represents the most important reward pathway. |
2008-04-14 |
2023-08-12 |
rat |
| J Russel Keath, Michael P Iacoviello, Lindy E Barrett, Huibert D Mansvelder, Daniel S McGehe. Differential modulation by nicotine of substantia nigra versus ventral tegmental area dopamine neurons. Journal of neurophysiology. vol 98. issue 6. 2008-03-05. PMID:17942622. |
the snc dopaminergic projections to the dorsal striatum are involved in voluntary movement and habit learning, whereas the vta projections to the ventral striatum contribute to reward and motivation. |
2008-03-05 |
2023-08-12 |
Not clear |
| Yann S Mineur, Marina R Picciott. Genetics of nicotinic acetylcholine receptors: Relevance to nicotine addiction. Biochemical pharmacology. vol 75. issue 1. 2008-02-26. PMID:17632086. |
genetic engineering studies in mice have identified a number of subunits that are critical for the ability of nicotine to activate the reward system in the brain, consisting of the dopaminergic cell bodies in the ventral tegmental area and their terminals in the nucleus accumbens and other portions of the mesolimbic system. |
2008-02-26 |
2023-08-12 |
mouse |
| Clemens Gruber, Anja Kahl, Lydia Lebenheim, Alexander Kowski, Anja Dittgen, Rüdiger W Ve. Dopaminergic projections from the VTA substantially contribute to the mesohabenular pathway in the rat. Neuroscience letters. vol 427. issue 3. 2008-02-25. PMID:17949902. |
recent evidence suggests that the lateral habenular complex (lhb) is a source of negative reward signals in midbrain dopaminergic neurons. |
2008-02-25 |
2023-08-12 |
rat |
| Frederic Boyer, Jean-Luc Dreye. Alpha-synuclein in the nucleus accumbens induces changes in cocaine behaviour in rats. The European journal of neuroscience. vol 26. issue 10. 2008-02-25. PMID:18001274. |
the mesolimbic dopaminergic system is widely recognized to be critical to the neurobiology of cocaine reward and addiction. |
2008-02-25 |
2023-08-12 |
rat |
| Christopher G Davey, Murat Yücel, Nicholas B Alle. The emergence of depression in adolescence: development of the prefrontal cortex and the representation of reward. Neuroscience and biobehavioral reviews. vol 32. issue 1. 2008-02-21. PMID:17570526. |
there is substantial remodeling and maturation of the dopaminergic reward system and the prefrontal cortex during adolescence, that coincides with the adolescent entering the complex world of adult peer and romantic relationships, where the rewards that can be obtained (feelings such as belonging, romantic love, status and agency) are abstract and temporally distant from the proximal context. |
2008-02-21 |
2023-08-12 |
Not clear |
| Xavier Caldú, Jean-Claude Drehe. Hormonal and genetic influences on processing reward and social information. Annals of the New York Academy of Sciences. vol 1118. 2008-02-20. PMID:17804523. |
less is known about the various factors influencing interindividual differences in reward processing and decision making in social contexts, both relying upon the dopaminergic system. |
2008-02-20 |
2023-08-12 |
human |
| Xavier Caldú, Jean-Claude Drehe. Hormonal and genetic influences on processing reward and social information. Annals of the New York Academy of Sciences. vol 1118. 2008-02-20. PMID:17804523. |
recent research combining molecular genetics, endocrinology, and neuroimaging demonstrated that variations in dopamine-related genes and in hormone levels affect the physiological properties of the dopaminergic system in nonhuman primates and modulate the processing of reward and social information in humans. |
2008-02-20 |
2023-08-12 |
human |
| Antonio Alcaro, Robert Huber, Jaak Panksep. Behavioral functions of the mesolimbic dopaminergic system: an affective neuroethological perspective. Brain research reviews. vol 56. issue 2. 2008-02-14. PMID:17905440. |
the mesolimbic dopaminergic (ml-da) system has been recognized for its central role in motivated behaviors, various types of reward, and, more recently, in cognitive processes. |
2008-02-14 |
2023-08-12 |
Not clear |
| Andrej Nikoshkov, Katarina Drakenberg, Xinyu Wang, Monika Cs Horvath, Eva Keller, Yasmin L Hur. Opioid neuropeptide genotypes in relation to heroin abuse: dopamine tone contributes to reversed mesolimbic proenkephalin expression. Proceedings of the National Academy of Sciences of the United States of America. vol 105. issue 2. 2008-02-06. PMID:18184800. |
we examined polymorphisms of proenkephalin (penk) and prodynorphin (pdyn) genes in relation to heroin abuse and gene expression in the human striatum and the relevance of genetic dopaminergic tone, critical for drug reward and striatal function. |
2008-02-06 |
2023-08-12 |
human |
| Juliana Yacubian, Tobias Sommer, Katrin Schroeder, Jan Gläscher, Dieter F Braus, Christian Büche. Subregions of the ventral striatum show preferential coding of reward magnitude and probability. NeuroImage. vol 38. issue 3. 2008-01-18. PMID:17889562. |
importantly, non-human primate data have revealed that single dopaminergic neurons code for both probability and magnitude of expected reward, suggesting an identical system. |
2008-01-18 |
2023-08-12 |
human |
| Birgit Völlm, Paul Richardson, Shane McKie, Rebecca Elliott, Mairead Dolan, Bill Deaki. Neuronal correlates of reward and loss in Cluster B personality disorders: a functional magnetic resonance imaging study. Psychiatry research. vol 156. issue 2. 2007-12-21. PMID:17920821. |
areas implicated in reward include ventral striatum, dopaminergic midbrain, amygdala and orbitofrontal cortex. |
2007-12-21 |
2023-08-12 |
human |
| Kenneth Blum, Thomas J H Chen, Brian Meshkin, Roger L Waite, B William Downs, Seth H Blum, Julie F Mengucci, Vanessa Arcuri, Eric R Braverman, Tomas Palom. Manipulation of catechol-O-methyl-transferase (COMT) activity to influence the attenuation of substance seeking behavior, a subtype of Reward Deficiency Syndrome (RDS), is dependent upon gene polymorphisms: a hypothesis. Medical hypotheses. vol 69. issue 5. 2007-12-13. PMID:17467918. |
in this regard we hypothesize that carrying the ll genotype with low comt activity should as theorized, increase the reward induced by substance-induced dopamine release and may indeed increase the propensity to type 1 alcoholism and possibly other drugs that activate the dopaminergic system. |
2007-12-13 |
2023-08-12 |
Not clear |
| Michael J Frank, Ahmed A Moustafa, Heather M Haughey, Tim Curran, Kent E Hutchiso. Genetic triple dissociation reveals multiple roles for dopamine in reinforcement learning. Proceedings of the National Academy of Sciences of the United States of America. vol 104. issue 41. 2007-11-28. PMID:17913879. |
here, we show with genetic analyses that three independent dopaminergic mechanisms contribute to reward and avoidance learning in humans. |
2007-11-28 |
2023-08-12 |
human |
| Bianca C Wittmann, Nico Bunzeck, Raymond J Dolan, Emrah Düze. Anticipation of novelty recruits reward system and hippocampus while promoting recollection. NeuroImage. vol 38. issue 1. 2007-11-26. PMID:17764976. |
the dopaminergic midbrain, which comprises the substantia nigra and ventral tegmental area (sn/vta), plays a central role in reward processing. |
2007-11-26 |
2023-08-12 |
human |
| Carmen Agustín-Pavón, Joana Martínez-Ricós, Fernando Martínez-García, Enrique Lanuz. Effects of dopaminergic drugs on innate pheromone-mediated reward in female mice: a new case of dopamine-independent "liking.". Behavioral neuroscience. vol 121. issue 5. 2007-11-20. PMID:17907824. |
effects of dopaminergic drugs on innate pheromone-mediated reward in female mice: a new case of dopamine-independent "liking.". |
2007-11-20 |
2023-08-12 |
mouse |
| Stephen A Varvel, Billy R Martin, Aron H Lichtma. Lack of behavioral sensitization after repeated exposure to THC in mice and comparison to methamphetamine. Psychopharmacology. vol 193. issue 4. 2007-10-23. PMID:17497137. |
recent evidence has provided support for the incentive-sensitization model of addiction, where repeated stimulation of neural reward circuits leads to a long-lasting sensitization of mesolimbic dopaminergic activity. |
2007-10-23 |
2023-08-12 |
mouse |
| David Weinshenker, Jason P Schroede. There and back again: a tale of norepinephrine and drug addiction. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 32. issue 7. 2007-08-31. PMID:17164822. |
however, reward experiments from the mid-1970s that could distinguish between the noradrenergic and dopaminergic systems resulted in the prevailing view that dopamine (da) was the primary 'reward transmitter' (a belief holding some sway still today), thereby pushing ne into the background. |
2007-08-31 |
2023-08-12 |
mouse |