| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M-B Assié, N Consul-Denjean, W Koek, A Newman-Tancred. Differential in vivo inhibition of [3H]nemonapride binding by atypical antipsychotics in rat striatum, olfactory lobes, and frontal cortex. Pharmacology. vol 75. issue 2. 2005-11-29. PMID:16020947. |
in the striatum, [3h]nemonapride binding was inhibited in a dose-dependent manner with the following order of potency (ed50, mg/kg): nemonapride (0.04), raclopride (0.13), spiperone and risperidone (0.14), haloperidol (0.21), clozapine (7.2) and thioridazine (9.4); in the olfactory lobes: nemonapride (0.03), raclopride and spiperone (0.09), haloperidol (0.10), risperidone (0.15), thioridazine and clozapine (11); in the frontal cortex, only the high affinity dopamine d2 antagonist compounds nemonapride (0.05), haloperidol (0.09), and raclopride (0.12) significantly decreased the binding of [3h]nemonapride. |
2005-11-29 |
2023-08-12 |
rat |
| Angela Pignatelli, Kazuto Kobayashi, Hideyuki Okano, Ottorino Belluzz. Functional properties of dopaminergic neurones in the mouse olfactory bulb. The Journal of physiology. vol 564. issue Pt 2. 2005-08-23. PMID:15731185. |
dopamine has been shown both in vivo and in vitro to modulate several aspects of olfactory information processing, but the functional properties of dopaminergic neurones have never been described due to the inability to recognize these cells in living preparations. |
2005-08-23 |
2023-08-12 |
mouse |
| K Stiasny-Kolster, Y Doerr, J C Möller, H Höffken, T M Behr, W H Oertel, G Maye. Combination of 'idiopathic' REM sleep behaviour disorder and olfactory dysfunction as possible indicator for alpha-synucleinopathy demonstrated by dopamine transporter FP-CIT-SPECT. Brain : a journal of neurology. vol 128. issue Pt 1. 2005-01-28. PMID:15548552. |
combination of 'idiopathic' rem sleep behaviour disorder and olfactory dysfunction as possible indicator for alpha-synucleinopathy demonstrated by dopamine transporter fp-cit-spect. |
2005-01-28 |
2023-08-12 |
human |
| Evelien Huisman, Harry B M Uylings, Piet V Hooglan. A 100% increase of dopaminergic cells in the olfactory bulb may explain hyposmia in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 19. issue 6. 2004-10-28. PMID:15197709. |
to determine whether the olfactory dysfunctions, like the motor symptoms, are associated with a loss of dopamine, the number of dopaminergic cells in the olfactory bulb of parkinson's disease patients was studied using tyrosine hydroxylase immunohistochemistry. |
2004-10-28 |
2023-08-12 |
Not clear |
| Evelien Huisman, Harry B M Uylings, Piet V Hooglan. A 100% increase of dopaminergic cells in the olfactory bulb may explain hyposmia in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 19. issue 6. 2004-10-28. PMID:15197709. |
because dopamine is known to inhibit olfactory transmission in the olfactory glomeruli, we suggest that the increase of dopaminergic neurons in the olfactory bulb is responsible for the hyposmia in parkinson patients. |
2004-10-28 |
2023-08-12 |
Not clear |
| Mirthe M Ponsen, Diederick Stoffers, Jan Booij, Berthe L F van Eck-Smit, Erik Ch Wolters, Henk W Berends. Idiopathic hyposmia as a preclinical sign of Parkinson's disease. Annals of neurology. vol 56. issue 2. 2004-09-20. PMID:15293269. |
a combination of olfactory detection, identification, and discrimination tasks was used to select groups of hyposmic (n = 40) and normosmic (n = 38) individuals for a 2-year clinical follow-up evaluation and sequential single-photon emission computed tomography (spect), using [123i]beta-cit as a dopamine transporter ligand, to assess nigrostriatal dopaminergic function at baseline and 2 years from baseline. |
2004-09-20 |
2023-08-12 |
Not clear |
| Cher V Masini, Philip V Holmes, Kimberly G Freeman, Alexandra C Maki, Gaylen L Edward. Dopamine overflow is increased in olfactory bulbectomized rats: an in vivo microdialysis study. Physiology & behavior. vol 81. issue 1. 2004-08-09. PMID:15059690. |
dopamine overflow is increased in olfactory bulbectomized rats: an in vivo microdialysis study. |
2004-08-09 |
2023-08-12 |
rat |
| Hiroko Sugiura, Ken Iwata, Masato Matsuoka, Hiroshi Hayashi, Takako Takemiya, Shin Yasuda, Masumi Ichikawa, Takashi Yamauchi, Patrick Mehlen, Tatsuya Haga, Kanato Yamagat. Inhibitory role of endophilin 3 in receptor-mediated endocytosis. The Journal of biological chemistry. vol 279. issue 22. 2004-07-29. PMID:15066995. |
furthermore, overexpression of endo3 in an olfactory epithelium-derived cell line suppressed dopamine d2 receptor-mediated endocytosis and therefore accelerated its dopamine-induced differentiation. |
2004-07-29 |
2023-08-12 |
Not clear |
| P C Hubbard, E N Barata, A V M Canári. Olfactory sensitivity to catecholamines and their metabolites in the goldfish. Chemical senses. vol 28. issue 3. 2004-01-05. PMID:12714443. |
this suggests that the olfactory catecholamine receptors are structurally and functionally distinct from systemic adreno- and dopamine receptors. |
2004-01-05 |
2023-08-12 |
Not clear |
| P C Hubbard, E N Barata, A V M Canári. Olfactory sensitivity to catecholamines and their metabolites in the goldfish. Chemical senses. vol 28. issue 3. 2004-01-05. PMID:12714443. |
the olfactory system of the goldfish was found to be sensitive to both adrenaline and dopamine with thresholds of detection of 10(-7.8) and 10(-7.9) m respectively, but less so to noradrenaline (threshold of detection 10(-6.3) m). |
2004-01-05 |
2023-08-12 |
Not clear |
| Martin Schwaerzel, Maria Monastirioti, Henrike Scholz, Florence Friggi-Grelin, Serge Birman, Martin Heisenber. Dopamine and octopamine differentiate between aversive and appetitive olfactory memories in Drosophila. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 33. 2003-12-11. PMID:14627633. |
here we investigate, in the fly drosophila melanogaster, the role of dopamine and octopamine (the presumed arthropod homolog of norepinephrine) during the formation of appetitive and aversive olfactory memories. |
2003-12-11 |
2023-08-12 |
drosophila_melanogaster |
| Martin Schwaerzel, Maria Monastirioti, Henrike Scholz, Florence Friggi-Grelin, Serge Birman, Martin Heisenber. Dopamine and octopamine differentiate between aversive and appetitive olfactory memories in Drosophila. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 33. 2003-12-11. PMID:14627633. |
dopamine and octopamine differentiate between aversive and appetitive olfactory memories in drosophila. |
2003-12-11 |
2023-08-12 |
drosophila_melanogaster |
| Hans Maaswinkel, Lei L. Olfactory input increases visual sensitivity in zebrafish: a possible function for the terminal nerve and dopaminergic interplexiform cells. The Journal of experimental biology. vol 206. issue Pt 13. 2003-11-04. PMID:12771169. |
intraocular injections of a dopamine d(2) but not a d(1) receptor antagonist blocked the effect of olfactory input on visual sensitivity. |
2003-11-04 |
2023-08-12 |
zebrafish |
| Robert A Schwartz, Eric R Greenwald, Paul J Fletcher, Sylvain Houle, Jean N DaSilv. Up-regulated dopamine D1 receptor binding can be detected in vivo following repeated SCH 23390, but not SKF 81297 or 6-hydroxydopamine, treatments. European journal of pharmacology. vol 459. issue 2-3. 2003-08-25. PMID:12524146. |
in contrast, repeated exposure with the dopamine d1 receptor antagonist sch 23390 significantly enhanced the uptake of [11c]sch 23390 in the dopamine d1 receptor-rich striatum and olfactory tubercles. |
2003-08-25 |
2023-08-12 |
rat |
| J Jeanblanc, A Hoeltzel, A Louilo. Differential involvement of dopamine in the anterior and posterior parts of the dorsal striatum in latent inhibition. Neuroscience. vol 118. issue 1. 2003-08-13. PMID:12676153. |
in contrast, dopamine levels in the non-pre-exposed experimental group (conditioned animals) remained fairly consistently close to the baseline after the presentation of the olfactory stimulus. |
2003-08-13 |
2023-08-12 |
rat |
| J Jeanblanc, A Hoeltzel, A Louilo. Differential involvement of dopamine in the anterior and posterior parts of the dorsal striatum in latent inhibition. Neuroscience. vol 118. issue 1. 2003-08-13. PMID:12676153. |
changes in extracellular dopamine levels induced by the conditioned olfactory stimulus (banana odor) were monitored in the two parts of the dorsal striatum in the left hemisphere after pre-exposure to the olfactory stimulus using in vivo voltammetry in freely moving rats. |
2003-08-13 |
2023-08-12 |
rat |
| Dean E Dluzen, June-Hee Park, Kyungjin Ki. Modulation of olfactory bulb tyrosine hydroxylase and catecholamine transporter mRNA by estrogen. Brain research. Molecular brain research. vol 108. issue 1-2. 2003-06-16. PMID:12480184. |
at 14 days post-hormonal treatment, the olfactory bulbs were assayed for mrna levels of tyrosine hydroxylase, dopamine transporter and norepinephrine transporter using competitive-pcr. |
2003-06-16 |
2023-08-12 |
mouse |
| K Mori, Y S Kaneko, A Nakashima, K Fujiwara, I Nagatsu, A Ot. Effect of peripheral lipopolysaccharide injection on dopamine content in murine anterior olfactory nucleus. Journal of neural transmission (Vienna, Austria : 1996). vol 110. issue 1. 2003-05-23. PMID:12541011. |
effect of peripheral lipopolysaccharide injection on dopamine content in murine anterior olfactory nucleus. |
2003-05-23 |
2023-08-12 |
mouse |
| J Jeanblanc, A Hoeltzel, A Louilo. Dissociation in the involvement of dopaminergic neurons innervating the core and shell subregions of the nucleus accumbens in latent inhibition and affective perception. Neuroscience. vol 111. issue 2. 2002-08-13. PMID:11983317. |
variations in extracellular dopamine levels induced by an aversively conditioned olfactory stimulus were monitored in the three parts of the nucleus accumbens in the left hemisphere, after pre-exposure to the olfactory stimulus using in vivo voltammetry in freely moving rats. |
2002-08-13 |
2023-08-12 |
rat |
| M Dahlin, B Jansson, E Björ. Levels of dopamine in blood and brain following nasal administration to rats. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. vol 14. issue 1. 2001-10-18. PMID:11457653. |
the aim of this study was to investigate the levels of [(3)h]dopamine in blood, the cerebrospinal fluid (csf) and brain tissue samples in rats and to find out whether the drug is transferred along the olfactory pathway to the central nervous system following nasal administration. |
2001-10-18 |
2023-08-12 |
rat |