| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Silke Nuber, Elisabeth Petrasch-Parwez, Oscar Arias-Carrión, Leanie Koch, Zacharias Kohl, Jacqueline Schneider, Carsten Calaminus, Rolf Dermietzel, Anna Samarina, Jana Boy, Huu P Nguyen, Peter Teismann, Thirumalaisamy Palanichamy Velavan, Philipp J Kahle, Stephan von Hörsten, Markus Fendt, Rejko Krüger, Olaf Ries. Olfactory neuron-specific expression of A30P α-synuclein exacerbates dopamine deficiency and hyperactivity in a novel conditional model of early Parkinson's disease stages. Neurobiology of disease. vol 44. issue 2. 2012-06-11. PMID:21767644. |
we found reversibly reduced levels of dopamine and metabolites in the ob, suggesting an impact of a30p α-syn on olfactory neurotransmitter content. |
2012-06-11 |
2023-08-12 |
mouse |
| Vidyulata Kamath, Paul J Moberg, Raquel E Gur, Richard L Doty, Bruce I Turetsk. Effects of the val(158)met catechol-O-methyltransferase gene polymorphism on olfactory processing in schizophrenia. Behavioral neuroscience. vol 126. issue 1. 2012-06-04. PMID:22148860. |
given the rich dopaminergic innervations of the olfactory bulb and the influence of dopamine on the transmission of olfactory signals, the authors examined the influence of comt genotype status on the olfactory processing impairment observed in schizophrenia. |
2012-06-04 |
2023-08-12 |
Not clear |
| Rui D S Prediger, Argelia E Rojas-Mayorquin, Aderbal S Aguiar, Caroline Chevarin, Raymond Mongeau, Michel Hamon, Laurence Lanfumey, Elaine Del Bel, Hisako Muramatsu, José Courty, Rita Raisman-Vozar. Mice with genetic deletion of the heparin-binding growth factor midkine exhibit early preclinical features of Parkinson's disease. Journal of neural transmission (Vienna, Austria : 1996). vol 118. issue 8. 2012-05-29. PMID:21301897. |
these findings indicate that the genetic deletion of midkine causes a partial loss of dopaminergic neurons and depletion of dopamine, resulting in olfactory and memory deficits with no major motor impairments. |
2012-05-29 |
2023-08-12 |
mouse |
| Martin Schecklmann, Matthias Schaldecker, Susanne Aucktor, Julia Brast, Katharina Kirchgässner, Andreas Mühlberger, Andreas Warnke, Manfred Gerlach, Andreas J Fallgatter, Marcel Romano. Effects of methylphenidate on olfaction and frontal and temporal brain oxygenation in children with ADHD. Journal of psychiatric research. vol 45. issue 11. 2012-03-15. PMID:21689828. |
olfaction and attention-deficit-/hyperactivity disorder (adhd) are mediated by dopamine metabolism and fronto-temporal functioning converging in recent findings of increased olfactory sensitivity in children with adhd modulated by methylphenidate (mph) and altered frontal and temporal oxygenation in adults with adhd. |
2012-03-15 |
2023-08-12 |
Not clear |
| Yichun Shuai, Ying Hu, Hongtao Qin, Robert A A Campbell, Yi Zhon. Distinct molecular underpinnings of Drosophila olfactory trace conditioning. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 50. 2012-02-01. PMID:22123966. |
these results suggest the mb as a crucial neuroanatomical locus for trace conditioning, which may harbor a rac activity-sensitive olfactory "sensory buffer" that later converges with the punishment signal carried by dopamine signaling. |
2012-02-01 |
2023-08-12 |
drosophila_melanogaster |
| Ka Kit Wong, Martijn L T M Muller, Hiroto Kuwabara, Stephanie A Studenski, Nicolaas I Bohne. Olfactory loss and nigrostriatal dopaminergic denervation in the elderly. Neuroscience letters. vol 484. issue 3. 2011-08-02. PMID:20727944. |
community-dwelling subjects (n=73, 44 f/29 m, mean age 64.0±16.4, range 20-85) underwent brain dopamine transporter (dat) [(11)c]2-β-carbomethoxy-3β-(4-fluorophenyl) tropane (β-cft) positron emission tomography (pet) imaging and olfactory assessment using the 40-odor university of pennsylvania smell identification test (upsit). |
2011-08-02 |
2023-08-12 |
human |
| M Vijaya Kumar, B Nirmala Kumari, K Yellamm. Zinc toxicity to aminergic neurotransmitters in rat brain. Toxicology international. vol 17. issue 2. 2011-07-14. PMID:21170245. |
dopamine, norepinephrine, and epinephrine and the catabolizing enzyme, monoamine oxidase (mao) were determined in different regions of rat brain such as olfactory lobe, hippocampus, cerebellum, and pons-medulla on selected time intervals/days under acute and chronic treatment with zinc. |
2011-07-14 |
2023-08-12 |
rat |
| Martin Schecklmann, Eva Schenk, Andreas Maisch, Susanne Kreiker, Christian Jacob, Andreas Warnke, Manfred Gerlach, Andreas J Fallgatter, Marcel Romano. Altered frontal and temporal brain function during olfactory stimulation in adult attention-deficit/hyperactivity disorder. Neuropsychobiology. vol 63. issue 2. 2011-05-25. PMID:21178380. |
olfactory processing depends on dopamine metabolism and orbitofrontal cortex functioning, both known to be disturbed in attention-deficit/hyperactivity disorder (adhd). |
2011-05-25 |
2023-08-12 |
Not clear |
| Andrea Carmine Belin, Marie Westerlund, Anna Anvret, Eva Lindqvist, Karin Pernold, Sven Ove Ogren, Gregg Duester, Dagmar Galte. Modeling Parkinson's disease genetics: altered function of the dopamine system in Adh4 knockout mice. Behavioural brain research. vol 217. issue 2. 2011-04-18. PMID:21075145. |
investigation of olfactory function revealed a reduced sense of smell in adh4-/- mice accompanied by alterations in dopamine metabolite levels in the olfactory bulb. |
2011-04-18 |
2023-08-12 |
mouse |
| Massimiliano Caiazzo, Luca Colucci-D'Amato, Floriana Volpicelli, Luisa Speranza, Ciro Petrone, Lucio Pastore, Stefano Stifani, Francesco Ramirez, Gian Carlo Bellenchi, Umberto di Porzi. Krüppel-like factor 7 is required for olfactory bulb dopaminergic neuron development. Experimental cell research. vol 317. issue 4. 2011-03-08. PMID:21093432. |
in particular, the tyrosine hydroxylase (th) and dopamine transporter (dat) transcripts are strongly decreased in the olfactory bulbs and ventral midbrain at birth, compared to wild-type littermates. |
2011-03-08 |
2023-08-12 |
mouse |
| W Sako, R Morigaki, S Nagahiro, R Kaji, S Got. Olfactory type G-protein alpha subunit in striosome-matrix dopamine systems in adult mice. Neuroscience. vol 170. issue 2. 2011-01-20. PMID:20603191. |
olfactory type g-protein alpha subunit in striosome-matrix dopamine systems in adult mice. |
2011-01-20 |
2023-08-12 |
mouse |
| W Sako, R Morigaki, S Nagahiro, R Kaji, S Got. Olfactory type G-protein alpha subunit in striosome-matrix dopamine systems in adult mice. Neuroscience. vol 170. issue 2. 2011-01-20. PMID:20603191. |
in this study, we used an immunohistochemical method to show differential expression of the olfactory type g-protein alpha subunit (galphaolf) that involves in the coupling of dopamine d1 receptor with adenylyl cyclase in the striatal compartments of adult mice, and observed heightened density of galphaolf labeling in the striosomes relative to the matrix compartment. |
2011-01-20 |
2023-08-12 |
mouse |
| Mirthe M Ponsen, Diederick Stoffers, Erik Ch Wolters, Jan Booij, Henk W Berends. Olfactory testing combined with dopamine transporter imaging as a method to detect prodromal Parkinson's disease. Journal of neurology, neurosurgery, and psychiatry. vol 81. issue 4. 2010-04-26. PMID:19965851. |
olfactory testing combined with dopamine transporter imaging as a method to detect prodromal parkinson's disease. |
2010-04-26 |
2023-08-12 |
Not clear |
| Mirthe M Ponsen, Diederick Stoffers, Erik Ch Wolters, Jan Booij, Henk W Berends. Olfactory testing combined with dopamine transporter imaging as a method to detect prodromal Parkinson's disease. Journal of neurology, neurosurgery, and psychiatry. vol 81. issue 4. 2010-04-26. PMID:19965851. |
methods in a cohort of 361 non-parkinsonian, non-demented first-degree relatives of pd patients, a combination of olfactory processing tasks was used to select groups of hyposmic (n=40) and normosmic (n=38) individuals for a 5-year clinical follow-up evaluation and sequential spect scanning, using a dopamine transporter ligand to assess nigrostriatal dopaminergic function at baseline and 5 years from baseline. |
2010-04-26 |
2023-08-12 |
Not clear |
| Henk W Berendse, Mirthe M Ponse. Diagnosing premotor Parkinson's disease using a two-step approach combining olfactory testing and DAT SPECT imaging. Parkinsonism & related disorders. vol 15 Suppl 3. 2010-03-31. PMID:20083001. |
in a prospective study in 361 asymptomatic first-degree relatives of pd patients, we studied the value of a two-step approach, combining olfactory testing and dopamine transporter (dat) spect imaging, in detecting patients in the premotor phase of pd. |
2010-03-31 |
2023-08-12 |
Not clear |
| Rui D S Prediger, Aderbal S Aguiar, Argelia Esperanza Rojas-Mayorquin, Claudia P Figueiredo, Filipe C Matheus, Laure Ginestet, Caroline Chevarin, Elaine Del Bel, Raymond Mongeau, Michel Hamon, Laurence Lanfumey, Rita Raisman-Vozar. Single intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57BL/6 mice models early preclinical phase of Parkinson's disease. Neurotoxicity research. vol 17. issue 2. 2010-03-02. PMID:19629612. |
administration of the proneurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) (1 mg/nostril) were similar to those observed during the early phase of pd, when a moderate loss of nigral dopamine neurons results in olfactory and memory deficits with no major motor impairments. |
2010-03-02 |
2023-08-12 |
mouse |
| Mareike Selcho, Dennis Pauls, Kyung-An Han, Reinhard F Stocker, Andreas S Thu. The role of dopamine in Drosophila larval classical olfactory conditioning. PloS one. vol 4. issue 6. 2009-11-17. PMID:19521527. |
the role of dopamine in drosophila larval classical olfactory conditioning. |
2009-11-17 |
2023-08-12 |
drosophila_melanogaster |
| Adam Claridge-Chang, Robert D Roorda, Eleftheria Vrontou, Lucas Sjulson, Haiyan Li, Jay Hirsh, Gero Miesenböc. Writing memories with light-addressable reinforcement circuitry. Cell. vol 139. issue 2. 2009-11-13. PMID:19837039. |
olfactory conditioning in drosophila requires direct dopamine action on intrinsic mushroom body neurons, the likely storage sites of olfactory memories. |
2009-11-13 |
2023-08-12 |
drosophila_melanogaster |
| Kyle T Beggs, Alison R Merce. Dopamine receptor activation by honey bee queen pheromone. Current biology : CB. vol 19. issue 14. 2009-11-02. PMID:19523830. |
these findings led to the hypothesis that hva targets dopamine pathways in the brain, which are known to play a critical role in the formation of aversive olfactory memories. |
2009-11-02 |
2023-08-12 |
bee |
| Megan E Breuer, Lucianne Groenink, Ronald S Oosting, Erich Buerger, Michiel Korte, Boris Ferger, Berend Olivie. Antidepressant effects of pramipexole, a dopamine D3/D2 receptor agonist, and 7-OH-DPAT, a dopamine D3 receptor agonist, in olfactory bulbectomized rats. European journal of pharmacology. vol 616. issue 1-3. 2009-10-19. PMID:19549514. |
antidepressant effects of pramipexole, a dopamine d3/d2 receptor agonist, and 7-oh-dpat, a dopamine d3 receptor agonist, in olfactory bulbectomized rats. |
2009-10-19 |
2023-08-12 |
rat |