| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Larsson, H Tjälv. Binding of aflatoxin B1 metabolites in extrahepatic tissues in fetal and infant mice and in adult mice with depleted glutathione levels. Cancer research. vol 52. issue 5. 1992-03-18. PMID:1737389. |
whole-body autoradiography of 3h-labeled aflatoxin b1 (afb1) in adult c57bl mice pretreated with the glutathione (gsh)-depleting agent phorone showed accumulation of tissue-bound radioactivity in the nasal olfactory and respiratory mucosa, the mucosa of the nasopharyngeal duct, and the tracheal and esophageal mucosa, which was not seen in unpretreated adult mice. |
1992-03-18 |
2023-08-11 |
mouse |
| P Larsson, H Tjälv. Binding of aflatoxin B1 metabolites in extrahepatic tissues in fetal and infant mice and in adult mice with depleted glutathione levels. Cancer research. vol 52. issue 5. 1992-03-18. PMID:1737389. |
the mechanism indicated above is supported by results of in vitro experiments in which the nasal olfactory mucosa and the esophageal mucosa were shown to have a capacity to form tissue-bound 3h-afb1 metabolites. |
1992-03-18 |
2023-08-11 |
mouse |
| P Larsson, H Tjälv. Binding of aflatoxin B1 metabolites in extrahepatic tissues in fetal and infant mice and in adult mice with depleted glutathione levels. Cancer research. vol 52. issue 5. 1992-03-18. PMID:1737389. |
in addition, the treatments of mice with phorone were shown to induce a strong gsh depletion in the nasal olfactory mucosa and the esophageal mucosa. |
1992-03-18 |
2023-08-11 |
mouse |
| P Larsson, H Tjälv. Binding of aflatoxin B1 metabolites in extrahepatic tissues in fetal and infant mice and in adult mice with depleted glutathione levels. Cancer research. vol 52. issue 5. 1992-03-18. PMID:1737389. |
in autoradiographic studies performed with 1- and 5-day-old infant mice a marked localization of bound 3h-afb1 metabolites was found in the nasal olfactory mucosa, and in the 5-day-old infant there was also a labeling of the mucosa of the nasopharyngeal duct, the pharyngeal and esophageal mucosa, and the tracheal mucosa. |
1992-03-18 |
2023-08-11 |
mouse |
| P Larsson, H Tjälv. Binding of aflatoxin B1 metabolites in extrahepatic tissues in fetal and infant mice and in adult mice with depleted glutathione levels. Cancer research. vol 52. issue 5. 1992-03-18. PMID:1737389. |
experiments in vitro with the nasal olfactory mucosa of 5-day-old infants demonstrated a marked binding of 3h-afb1 metabolites in this tissue. |
1992-03-18 |
2023-08-11 |
mouse |
| P Larsson, H Tjälv. Binding of aflatoxin B1 metabolites in extrahepatic tissues in fetal and infant mice and in adult mice with depleted glutathione levels. Cancer research. vol 52. issue 5. 1992-03-18. PMID:1737389. |
autoradiography of 3h-afb1 in pregnant mice showed a labeling of the fetal nasal olfactory mucosa at day 18 but not at day 14 of gestation. |
1992-03-18 |
2023-08-11 |
mouse |
| P Larsson, H Tjälv. Binding of aflatoxin B1 metabolites in extrahepatic tissues in fetal and infant mice and in adult mice with depleted glutathione levels. Cancer research. vol 52. issue 5. 1992-03-18. PMID:1737389. |
this indicates that afb1-bioactivating enzymes develop in the fetal nasal olfactory mucosa in late gestation. |
1992-03-18 |
2023-08-11 |
mouse |
| J D Foster, M L Getchell, T V Getchel. Ultrastructural localization of sialylated glycoconjugates in cells of the salamander olfactory mucosa using lectin cytochemistry. Cell and tissue research. vol 267. issue 1. 1992-03-12. PMID:1735108. |
in the olfactory mucus, the density of lectin binding sites was greater in the region of mucus closest to the nasal cavity than in that closest to the epithelial surface. |
1992-03-12 |
2023-08-11 |
Not clear |
| M Narita, T Imada, M Haritan. Immunohistological demonstration of spread of Aujeszky's disease virus via the olfactory pathway in HPCD pigs. Journal of comparative pathology. vol 105. issue 2. 1992-03-10. PMID:1663956. |
the spread of aujeszky's disease virus (adv) from nasal mucosa via the olfactory pathway was studied in hpcd pigs. |
1992-03-10 |
2023-08-11 |
Not clear |
| B R Talamo, W H Feng, M Perez-Cruet, L Adelman, K Kosik, M Y Lee, L C Cork, J S Kaue. Pathologic changes in olfactory neurons in Alzheimer's disease. Annals of the New York Academy of Sciences. vol 640. 1992-02-28. PMID:1776726. |
we hypothesized that peripheral olfactory neurons that reside in the nasal epithelium would show degenerative changes similar to the characteristic pathologic features of ad brain. |
1992-02-28 |
2023-08-11 |
monkey |
| J Gottofrey, H Tjälv. Axonal transport of cadmium in the olfactory nerve of the pike. Pharmacology & toxicology. vol 69. issue 4. 1991-12-31. PMID:1720248. |
when the nasal chambers were washed 2 hr after application of the 109cd2+ well-defined transport peaks for the metal were seen in the olfactory axons. |
1991-12-31 |
2023-08-11 |
Not clear |
| T N Dear, K Campbell, T H Rabbitt. Molecular cloning of putative odorant-binding and odorant-metabolizing proteins. Biochemistry. vol 30. issue 43. 1991-12-02. PMID:1931961. |
olfactory reception occurs via the interaction of odorants with the chemosensory cilia of the olfactory receptor cells located in the nasal epithelium. |
1991-12-02 |
2023-08-11 |
Not clear |
| J Van Benthem, C P Wild, E Vermeulen, L Den Engelse, E Schere. Immunocytochemical localization of DNA adducts induced by a single dose of N-nitroso-N-methylbenzylamine in target and non-target tissues of tumor formation in the rat. Carcinogenesis. vol 12. issue 10. 1991-11-25. PMID:1934264. |
dose-dependent dna methylation was seen, both at 6 and 72 h, in other non-target organs such as lung (bronchiolar epithelial cells), trachea (epithelial and glandular cells) and nasal cavity (respiratory epithelial cells, ductal cells of the respiratory lamina propria and cells of bowman glands of the olfactory lamina propria); the nuclei of the glandular cells were highly methylated. |
1991-11-25 |
2023-08-11 |
rat |
| E B Brittebo, C Eriksson, V Feil, J Bakke, I Brand. Toxicity of 2,6-dichlorothiobenzamide (chlorthiamid) and 2,6-dichlorobenzamide in the olfactory nasal mucosa of mice. Fundamental and applied toxicology : official journal of the Society of Toxicology. vol 17. issue 1. 1991-11-13. PMID:1916084. |
toxicity of 2,6-dichlorothiobenzamide (chlorthiamid) and 2,6-dichlorobenzamide in the olfactory nasal mucosa of mice. |
1991-11-13 |
2023-08-11 |
mouse |
| E B Brittebo, C Eriksson, V Feil, J Bakke, I Brand. Toxicity of 2,6-dichlorothiobenzamide (chlorthiamid) and 2,6-dichlorobenzamide in the olfactory nasal mucosa of mice. Fundamental and applied toxicology : official journal of the Society of Toxicology. vol 17. issue 1. 1991-11-13. PMID:1916084. |
dcba was also toxic to the olfactory region (100 mg/kg), inducing necrosis of the bowman's glands and the neuroepithelium in the dorsomedial region of the nasal cavity. |
1991-11-13 |
2023-08-11 |
mouse |
| D Y Stainier, D H Bilder, W Gilber. Spatial domains in the developing forebrain: developmental regulation of a restricted cell surface protein. Developmental biology. vol 147. issue 1. 1991-10-02. PMID:1879609. |
the olfactory, otic, and hypophyseal placodes, which can be identified as early as e10, are also 52g9 positive as are their derivatives, the sensory epithelial of the nasal passage and inner ear, and also rathke's pouch. |
1991-10-02 |
2023-08-11 |
rat |
| J A Matochik, C N Reems, B M Wenze. A brain atlas of the northern fulmar (Fulmarus glacialis) in stereotaxic coordinates. Brain, behavior and evolution. vol 37. issue 4. 1991-10-01. PMID:1878776. |
the nasal cavity and olfactory bulb of most procellariiforms are among the largest of all avian orders; the central olfactory pathways may be more extensive as well. |
1991-10-01 |
2023-08-11 |
Not clear |
| R C Kern, T P Kerr, T V Getchel. Ultrastructural localization of Na+/K(+)-ATPase in rodent olfactory epithelium. Brain research. vol 546. issue 1. 1991-08-23. PMID:1649670. |
the sensory neurons have apical knobs and cilia, which project into the olfactory mucus toward the nasal lumen, and represent presumptive sites of odorant binding. |
1991-08-23 |
2023-08-11 |
Not clear |
| C Eriksson, E B Britteb. Epithelial binding of 1,1,2,2-tetrachloroethane in the respiratory and upper alimentary tract. Archives of toxicology. vol 65. issue 1. 1991-07-11. PMID:2043045. |
injected mice, a high and selective localization of bound metabolites occurred in the nasal olfactory mucosa, preferentially in the bowman's glands. |
1991-07-11 |
2023-08-11 |
mouse |
| A Fise. Changes of olfaction due to aesthetic and functional nose surgery. Acta oto-rhino-laryngologica Belgica. vol 44. issue 4. 1991-06-20. PMID:2093289. |
the swelling of the nasal mucous membrane in olfactory region is the reason for temporary abnormalities of the smell function. |
1991-06-20 |
2023-08-11 |
Not clear |