| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M B Genter, J Llorens, J P O'Callaghan, D B Peele, K T Morgan, K M Crofto. Olfactory toxicity of beta,beta'-iminodipropionitrile in the rat. The Journal of pharmacology and experimental therapeutics. vol 263. issue 3. 1993-01-22. PMID:1469644. |
nasal cavities were fixed, decalcified and embedded in paraffin; 5 microns sections were stained with hematoxylin and eosin, middle neurofilament protein antibody or olfactory marker protein antiserum. |
1993-01-22 |
2023-08-11 |
rat |
| E Walters, K Buchheit, J A Marunia. Receptor neuron losses result in decreased cytochrome P-450 immunoreactivity in associated non-neuronal cells of mouse olfactory mucosa. Journal of neuroscience research. vol 33. issue 1. 1993-01-06. PMID:1453475. |
immunohistochemical and immunoblot analyses were used to investigate nasal cytochrome p-450 distribution in mice with either unilateral naris closure for 3, 4, or 5 months, or olfactory bulbectomy. |
1993-01-06 |
2023-08-11 |
mouse |
| J Y Hong, X Ding, T J Smith, M J Coon, C S Yan. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific carcinogen, by rabbit nasal microsomes and cytochrome P450s NMa and NMb. Carcinogenesis. vol 13. issue 11. 1992-12-22. PMID:1423886. |
rabbit nasal olfactory and respiratory microsomes were found to catalyze the alpha-hydroxylation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (nnk) with specific activities of 262 and 136 pmol/min/mg protein in the formation of keto aldehyde, and of 318 and 190 pmol/min/mg protein in the formation of keto alcohol respectively. |
1992-12-22 |
2023-08-11 |
rat |
| J Y Hong, X Ding, T J Smith, M J Coon, C S Yan. Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific carcinogen, by rabbit nasal microsomes and cytochrome P450s NMa and NMb. Carcinogenesis. vol 13. issue 11. 1992-12-22. PMID:1423886. |
the formation of nnk-n-oxide was observed in experiments with rabbit olfactory and respiratory microsomes, but not with rat nasal microsomes. |
1992-12-22 |
2023-08-11 |
rat |
| B P Menc. Lectins bind differentially to cilia and microvilli of major and minor cell populations in olfactory and nasal respiratory epithelia. Microscopy research and technique. vol 23. issue 2. 1992-12-16. PMID:1421555. |
lectins bind differentially to cilia and microvilli of major and minor cell populations in olfactory and nasal respiratory epithelia. |
1992-12-16 |
2023-08-11 |
rat |
| Y Chen, M L Getchell, X Ding, T V Getchel. Immunolocalization of two cytochrome P450 isozymes in rat nasal chemosensory tissue. Neuroreport. vol 3. issue 9. 1992-12-09. PMID:1421130. |
the nma and nmb isoforms of cytochrome p450 enzymes are expressed in three nasal chemosensory organs: the olfactory, septal and vomeronasal mucosae. |
1992-12-09 |
2023-08-11 |
rat |
| S Murakami, S Kikuyama, Y Ara. The origin of the luteinizing hormone-releasing hormone (LHRH) neurons in newts (Cynops pyrrhogaster): the effect of olfactory placode ablation. Cell and tissue research. vol 269. issue 1. 1992-12-02. PMID:1423481. |
removal of the olfactory placode results in the absence of lhrh-immunoreactive cells in the nasal and brain regions of the operated side, whereas the subsequent growth and the lhrh-immunoreactive cellular distribution in the contralateral side are identical to those of normal larvae. |
1992-12-02 |
2023-08-11 |
Not clear |
| D R Adam. Fine structure of the vomeronasal and septal olfactory epithelia and of glandular structures. Microscopy research and technique. vol 23. issue 1. 1992-11-17. PMID:1392074. |
the vomeronasal and septal olfactory organs are two neurosensory structures in the mammalian nasal septum which are poorly understood relative to the main olfactory system. |
1992-11-17 |
2023-08-11 |
cattle |
| D R Adam. Fine structure of the vomeronasal and septal olfactory epithelia and of glandular structures. Microscopy research and technique. vol 23. issue 1. 1992-11-17. PMID:1392074. |
when present in mammals, the septal olfactory organ is an island of olfactory mucosa positioned such that it is in the primary air pathway in the caudal portion of the nasal cavity. |
1992-11-17 |
2023-08-11 |
cattle |
| D R Adam. Fine structure of the vomeronasal and septal olfactory epithelia and of glandular structures. Microscopy research and technique. vol 23. issue 1. 1992-11-17. PMID:1392074. |
one of these substances, odorant binding protein, localized in bovine nasal glands and lateral nasal glands of rodents, may be important in the capture and conveyance of odorant molecules to olfactory receptors. |
1992-11-17 |
2023-08-11 |
cattle |
| D R Adam. Fine structure of the vomeronasal and septal olfactory epithelia and of glandular structures. Microscopy research and technique. vol 23. issue 1. 1992-11-17. PMID:1392074. |
the objectives of this paper are to present original data while reviewing the literature on the ultrastructure of vomeronasal and septal olfactory neuroepithelia, and of vomeronasal, bovine nasal, and lateral nasal glands. |
1992-11-17 |
2023-08-11 |
cattle |
| A J Apter, A E Mott, W S Cain, J D Spiro, M C Barwic. Olfactory loss and allergic rhinitis. The Journal of allergy and clinical immunology. vol 90. issue 4 Pt 1. 1992-11-06. PMID:1401646. |
recent olfactory loss in the absence of nasal symptoms and in the absence of abnormalities in the nasal cavity should suggest further investigation to look for a more central process. |
1992-11-06 |
2023-08-11 |
Not clear |
| N Giannetti, D Saucier, L Asti. Organization of the septal organ projection to the main olfactory bulb in adult and newborn rats. The Journal of comparative neurology. vol 323. issue 2. 1992-11-03. PMID:1383286. |
the septal organ, which is regarded as an olfactory subsystem, is a small patch of sensory epithelium located ventral to the main olfactory sheet on the septal wall of the nasal cavity. |
1992-11-03 |
2023-08-11 |
rat |
| D L Zaret, N Morrison, R Gulbranson, D F Kere. Immunofixation to quantify beta 2-transferrin in cerebrospinal fluid to detect leakage of cerebrospinal fluid from skull injury. Clinical chemistry. vol 38. issue 9. 1992-10-20. PMID:1526033. |
use of this technique to examine rhinorrhea in a motor-vehicle-accident patient confirmed leakage of csf into the nasal cavity through a vent in the left olfactory groove. |
1992-10-20 |
2023-08-11 |
Not clear |
| H Tjälve, P Larsson, C Andersson, L Bus. Bioactivation of aflatoxin B1 in the bovine olfactory mucosa: DNA binding, mutagenicity and induction of sister chromatid exchanges. Carcinogenesis. vol 13. issue 8. 1992-09-16. PMID:1499086. |
nasal olfactory tumours occur in cattle in relatively high frequencies in several developing countries. |
1992-09-16 |
2023-08-11 |
mouse |
| H Tjälve, P Larsson, C Andersson, L Bus. Bioactivation of aflatoxin B1 in the bovine olfactory mucosa: DNA binding, mutagenicity and induction of sister chromatid exchanges. Carcinogenesis. vol 13. issue 8. 1992-09-16. PMID:1499086. |
incubations of microsomal preparations of the bovine nasal olfactory mucosa with glutathione (gsh) and cytosolic fractions of the nasal mucosa resulted in decreased afb1 dna binding. |
1992-09-16 |
2023-08-11 |
mouse |
| H Tjälve, P Larsson, C Andersson, L Bus. Bioactivation of aflatoxin B1 in the bovine olfactory mucosa: DNA binding, mutagenicity and induction of sister chromatid exchanges. Carcinogenesis. vol 13. issue 8. 1992-09-16. PMID:1499086. |
our results indicate that afb1-gsh conjugation occurs less efficiently in the bovine nasal olfactory mucosa than in the mouse liver. |
1992-09-16 |
2023-08-11 |
mouse |
| H Tjälve, P Larsson, C Andersson, L Bus. Bioactivation of aflatoxin B1 in the bovine olfactory mucosa: DNA binding, mutagenicity and induction of sister chromatid exchanges. Carcinogenesis. vol 13. issue 8. 1992-09-16. PMID:1499086. |
supernatant preparations (9000 g) of the bovine nasal olfactory mucosa incubated with afb1 were shown to have the capacity to induce a strong genotoxic response both as regards induction of gene mutations in salmonella typhimurium ta100 and the induction of sister chromatid exchanges in chinese hamster ovary cells. |
1992-09-16 |
2023-08-11 |
mouse |
| H Tjälve, P Larsson, C Andersson, L Bus. Bioactivation of aflatoxin B1 in the bovine olfactory mucosa: DNA binding, mutagenicity and induction of sister chromatid exchanges. Carcinogenesis. vol 13. issue 8. 1992-09-16. PMID:1499086. |
the results of the present study show that the bovine nasal olfactory mucosa has a high afb1-bioactivating capacity, which can be related to the potent dna damaging and mutagenic effects observed. |
1992-09-16 |
2023-08-11 |
mouse |
| K W Delan. [Olfactory sensitivity in adenoid hyperplasia]. Laryngo- rhino- otologie. vol 71. issue 6. 1992-09-03. PMID:1637448. |
the results suggest that preoperative olfactory detection thresholds in subjects with severe nasal obstruction attributable to adenoid hypertrophy are higher than in those with less severe nasal obstruction. |
1992-09-03 |
2023-08-11 |
human |