Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Xiaojuan Liu, Hui Ma, Lisha Ma, Kun Li, Yanhua Kan. The potential role of methyltransferase-like 5 in deficient mismatch repair of uterine corpus endometrial carcinoma. Bioengineered. vol 13. issue 3. 2022-02-15. PMID:35166644. |
mettl5 was negatively correlated with gene silencing, mrna binding, olfactory receptor activity, antigen processing and presentation, cytosolic dna sensing, olfactory transduction, and rig-1-like and toll-like receptor signaling pathways. |
2022-02-15 |
2023-08-13 |
Not clear |
Bingjie Li, Marissa L Kamarck, Qianqian Peng, Fei-Ling Lim, Andreas Keller, Monique A M Smeets, Joel D Mainland, Sijia Wan. From musk to body odor: Decoding olfaction through genetic variation. PLoS genetics. vol 18. issue 2. 2022-02-03. PMID:35113854. |
the olfactory system combines input from multiple receptor types to represent odor information, but there are few explicit examples relating olfactory receptor (or) activity patterns to odor perception. |
2022-02-03 |
2023-08-13 |
human |
Leisl Imani Brewster, Benjamin John Matthew. Seeing smell: the structural underpinnings of insect olfaction. Trends in biochemical sciences. 2021-12-19. PMID:34922796. |
describe cryo-electron microscopy (cryo-em) structures of an insect olfactory receptor (or) ion channel, detailing the mechanism by which odorants can directly gate ion flow and providing insights into how this incredibly diverse family of receptors have evolved to support insects navigating complex olfactory landscapes. |
2021-12-19 |
2023-08-13 |
Not clear |
Mario Pannunzi, Thomas Nowotn. Non-synaptic interactions between olfactory receptor neurons, a possible key feature of odor processing in flies. PLoS computational biology. vol 17. issue 12. 2021-12-13. PMID:34898600. |
with a computational model of the drosophila olfactory system, we analyze the utility of an alternative mechanism for solving them: non-synaptic ("ephaptic") interactions (nsis) between olfactory receptor neurons that are stereotypically co-housed in the same sensilla. |
2021-12-13 |
2023-08-13 |
drosophila_melanogaster |
Simon Yung Wa Sin, Alison Cloutier, Gabrielle Nevitt, Scott V Edward. Olfactory receptor subgenome and expression in a highly olfactory procellariiform seabird. Genetics. 2021-12-10. PMID:34888634. |
olfactory receptor subgenome and expression in a highly olfactory procellariiform seabird. |
2021-12-10 |
2023-08-13 |
Not clear |
Hyeyoun Kim, See-Hyoung Park, Sae Woong Oh, Kitae Kwon, Se Jung Park, Eunbi Yu, Seyoung Yang, Jung Yoen Park, Seoyoung Choi, Seoyoun Yang, Su Bin Han, Minkyung Song, Jae Youl Cho, Jongsung Le. Olfactory Receptor OR7A17 Expression Correlates with All- International journal of molecular sciences. vol 22. issue 22. 2021-11-30. PMID:34830183. |
olfactory receptor or7a17 expression correlates with all- olfactory receptors (ors), which belong to the g-protein-coupled receptor family, have been widely studied as ectopically expressed receptors in various human tissues, including the skin. |
2021-11-30 |
2023-08-13 |
human |
Yue-Nan Zhou, Shuang Xie, Jia-Ni Chen, Ze-Hua Wang, Pei Yang, Si-Cong Zhou, Lan Pang, Fei Li, Min Shi, Jian-Hua Huang, Xue-Xin Che. Expression and functional characterization of odorant-binding protein genes in the endoparasitic wasp Cotesia vestalis. Insect science. vol 28. issue 5. 2021-11-29. PMID:32761881. |
odorant-binding proteins (obps) are crucial in insect's olfactory perception, which participate in the initial step of odorant molecules transporting from the external environment to olfactory receptor neurons. |
2021-11-29 |
2023-08-13 |
Not clear |
Gordon M Shepherd, Timothy B Rowe, Charles A Gree. An Evolutionary Microcircuit Approach to the Neural Basis of High Dimensional Sensory Processing in Olfaction. Frontiers in cellular neuroscience. vol 15. 2021-11-24. PMID:33994949. |
paleontology provides a unique advantage with evolutionary insights providing evidence that the basic architecture of the olfactory pathway almost from the start ∼330 million years ago (mya) has included an overwhelming input from olfactory sensory neurons combined with a large olfactory bulb and olfactory cortex to process that input, driven by olfactory receptor gene duplications. |
2021-11-24 |
2023-08-13 |
Not clear |
Iliano V Coutinho-Abreu, Jeffrey A Riffell, Omar S Akbar. Human attractive cues and mosquito host-seeking behavior. Trends in parasitology. 2021-11-11. PMID:34674963. |
mosquitoes detect these compounds using olfactory receptors in their antennal olfactory receptor neurons. |
2021-11-11 |
2023-08-13 |
human |
Rodi Topci, Mihai Alevra, Erik H U Rauf, Daniëlle de Jong-Bol. Resolving different presynaptic activity patterns within single olfactory glomeruli of Xenopus laevis larvae. Scientific reports. vol 11. issue 1. 2021-11-08. PMID:34244587. |
olfactory sensing is generally organized into groups of similarly sensing olfactory receptor neurons converging into their corresponding glomerulus, which is thought to behave as a uniform functional unit. |
2021-11-08 |
2023-08-13 |
xenopus_laevis |
Rodi Topci, Mihai Alevra, Erik H U Rauf, Daniëlle de Jong-Bol. Resolving different presynaptic activity patterns within single olfactory glomeruli of Xenopus laevis larvae. Scientific reports. vol 11. issue 1. 2021-11-08. PMID:34244587. |
here we investigate activity of olfactory receptor neurons and their axon terminals throughout olfactory glomeruli using electrophysiological recordings and rapid 4d calcium imaging. |
2021-11-08 |
2023-08-13 |
xenopus_laevis |
Tongchao Li, Liqun Lu. An Explant System for Time-Lapse Imaging Studies of Olfactory Circuit Assembly in Drosophila. Journal of visualized experiments : JoVE. issue 176. 2021-11-01. PMID:34723938. |
the drosophila olfactory system provides an excellent model to investigate this process since 50 types of olfactory receptor neurons (orns) from the antennae and maxillary palps project their axons to 50 identifiable glomeruli in the antennal lobe and form synaptic connections with dendrites from 50 types of second-order projection neurons (pns). |
2021-11-01 |
2023-08-13 |
drosophila_melanogaster |
Tongchao Li, Tian-Ming Fu, Kenneth Kin Lam Wong, Hongjie Li, Qijing Xie, David J Luginbuhl, Mark J Wagner, Eric Betzig, Liqun Lu. Cellular bases of olfactory circuit assembly revealed by systematic time-lapse imaging. Cell. vol 184. issue 20. 2021-10-27. PMID:34551316. |
here, we use the drosophila olfactory circuit to investigate dynamic cellular processes by which olfactory receptor neurons (orns) target axons precisely to specific glomeruli in the ipsi- and contralateral antennal lobes. |
2021-10-27 |
2023-08-13 |
drosophila_melanogaster |
Chiquito J Crast. Computational Biology of Olfactory Receptors. Current bioinformatics. vol 4. issue 1. 2021-10-20. PMID:21984880. |
we present here a review of the research efforts in: creating computational models of olfactory receptors, identifying binding strategies for these receptors with odorant molecules, performing medium to long range simulation studies of odor ligands in the receptor binding region, and identifying amino acid positions within the receptor that are responsible for ligand-binding and olfactory receptor activation. |
2021-10-20 |
2023-08-12 |
Not clear |
Elizabeth A Corey, Kirill Ukhanov, Yuriy V Bobkov, Jeremy C McIntyre, Jeffrey R Martens, Barry W Ach. Inhibitory signaling in mammalian olfactory transduction potentially mediated by Gα Molecular and cellular neurosciences. vol 110. 2021-10-13. PMID:33358996. |
inhibitory signaling in mammalian olfactory transduction potentially mediated by gα olfactory gpcrs (ors) in mammalian olfactory receptor neurons (orns) mediate excitation through the gα |
2021-10-13 |
2023-08-13 |
Not clear |
Han Liu, Chunhai Chen, Maolin Lv, Ning Liu, Yafei Hu, Hailin Zhang, Erik D Enbody, Zexia Gao, Leif Andersson, Weimin Wan. A Chromosome-Level Assembly of Blunt Snout Bream (Megalobrama amblycephala) Genome Reveals an Expansion of Olfactory Receptor Genes in Freshwater Fish. Molecular biology and evolution. vol 38. issue 10. 2021-09-29. PMID:34003267. |
the number of olfactory receptor genes (ors), which are responsible for detecting diverse odor molecules varies extensively among mammals as a result of frequent gene gains and losses that contribute to olfactory specialization. |
2021-09-29 |
2023-08-13 |
Not clear |
Petra Mermer, Jörg Strotmann, Wolfgang Kummer, Renate Paddenber. Olfactory receptor Olfr78 (prostate-specific G protein-coupled receptor PSGR) expression in arterioles supplying skeletal and cardiac muscles and in arterioles feeding some murine organs. Histochemistry and cell biology. 2021-09-21. PMID:34545457. |
the olfactory receptor olfr78 (prostate-specific g protein-coupled receptor psgr) is a member of the g protein-coupled receptor family mediating olfactory chemosensation, but it is additionally expressed in other tissues. |
2021-09-21 |
2023-08-13 |
mouse |
Michele Dibattista, Dolly Al Koborssy, Federica Genovese, Johannes Reiser. The functional relevance of olfactory marker protein in the vertebrate olfactory system: a never-ending story. Cell and tissue research. vol 383. issue 1. 2021-09-16. PMID:33447880. |
olfactory marker protein (omp) was first described as a protein expressed in olfactory receptor neurons (orns) in the nasal cavity. |
2021-09-16 |
2023-08-13 |
mouse |
Ismahene Ben Khemis, Abir Sagaama, Noureddine Issaoui, Abdelmottaleb Ben Lamin. Steric and energetic characterizations of mouse and human musk receptors activated by nitro musk smelling compounds at molecular level: Statistical physics treatment and molecular docking analysis. International journal of biological macromolecules. vol 188. 2021-09-16. PMID:34389381. |
a statistical physics modeling using the monolayer model with two independent types of receptor binding sites of the response of the mouse olfactory receptor mor215-1 and the human olfactory receptor or5an1, which are identified as specifically responding to musk compounds, is used to characterize the interaction between the two nitro musk molecules, the mouse and the human olfactory receptors and to determine the olfactory band of these two odorants through the determination of the molar adsorption energies and the adsorption energy distributions. |
2021-09-16 |
2023-08-13 |
mouse |
Kristian J Herrera, Thomas Panier, Drago Guggiana-Nilo, Florian Enger. Larval Zebrafish Use Olfactory Detection of Sodium and Chloride to Avoid Salt Water. Current biology : CB. vol 31. issue 4. 2021-08-24. PMID:33338431. |
further, we use calcium imaging techniques to identify the olfactory system as the primary sense used for salt detection, and we find that a specific subset of olfactory receptor neurons encodes absolute salinity concentrations by detecting monovalent anions and cations. |
2021-08-24 |
2023-08-13 |
zebrafish |