| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Brian Kim, Seth Haney, Ana P Milan, Shruti Joshi, Zane Aldworth, Nikolai Rulkov, Alexander T Kim, Maxim Bazhenov, Mark A Stopfe. Olfactory receptor neurons generate multiple response motifs, increasing coding space dimensionality. eLife. vol 12. 2023-01-31. PMID:36719272. |
odorants binding to olfactory receptor neurons (orns) trigger bursts of action potentials, providing the brain with its only experience of the olfactory environment. |
2023-01-31 |
2023-08-14 |
Not clear |
| Simon Bérubé, Claudia Demers, Nicholas Bussière, Frank Cloutier, Valérie Pek, Angela Chen, Josiane Bolduc-Bégin, Johannes Frasnell. Olfactory Training Impacts Olfactory Dysfunction Induced by COVID-19: A Pilot Study. ORL; journal for oto-rhino-laryngology and its related specialties. 2022-12-18. PMID:36529118. |
this approach is thought of promoting the regeneration of olfactory receptor cells, but its effectiveness in patients with post-covid-19 olfactory dysfunction has yet to be confirmed. |
2022-12-18 |
2023-08-14 |
Not clear |
| Rafal Butowt, Katarzyna Bilinska, Christopher S von Barthel. Olfactory dysfunction in COVID-19: new insights into the underlying mechanisms. Trends in neurosciences. 2022-12-05. PMID:36470705. |
among the current hypotheses, the most plausible is that death of infected support cells in the olfactory epithelium causes, besides altered composition of the mucus, retraction of the cilia on olfactory receptor neurons, possibly because of the lack of support cell-derived glucose in the mucus, which powers olfactory signal transduction within the cilia. |
2022-12-05 |
2023-08-14 |
Not clear |
| Noriyuki Nakashima, Akiko Nakashima, Kie Nakashima, Makoto Takan. Olfactory marker protein contains a leucine-rich domain in the Ω-loop important for nuclear export. Molecular brain. vol 15. issue 1. 2022-11-05. PMID:36333725. |
olfactory marker protein (omp) is a cytosolic protein expressed in mature olfactory receptor neurons (orns). |
2022-11-05 |
2023-08-14 |
Not clear |
| Noriyuki Nakashima, Kie Nakashima, Akiko Nakashima, Makoto Takan. Olfactory marker protein is unlikely to be cleaved by calpain 5. Molecular brain. vol 15. issue 1. 2022-10-30. PMID:36309704. |
olfactory maturation marker protein (omp) is expressed in olfactory receptor neurons and hypothalamic neurons. |
2022-10-30 |
2023-08-14 |
Not clear |
| Ismahene Ben Khemis, Olfa Noureddine, Fatma Aouaini, Amjad Salamah M Aljaloud, Samia Nasr, Abdelmottaleb Ben Lamin. Indirect characterizations of mOR-EG: Modeling analysis of five concentration-olfactory response curves via an advanced monolayer adsorption model. International journal of biological macromolecules. 2022-10-04. PMID:36195222. |
the investigation of the adsorption process putatively involved in the olfactory perception of apocynin, guaiacylacetone, homovanillyl alcohol, 4-ethylguaiacol and homoguaiacol molecules on the mouse eugenol olfactory receptor mor-eg was a very useful tool for comprising olfaction process at a molecular level. |
2022-10-04 |
2023-08-14 |
mouse |
| Haoran Luo, Site Luo, Wenzhen Fang, Qingxian Lin, Xiaolin Chen, Xiaoping Zho. Genomic insight into the nocturnal adaptation of the black-crowned night heron (Nycticorax nycticorax). BMC genomics. vol 23. issue 1. 2022-10-03. PMID:36192687. |
in this study, the whole genome of n. nycticorax was sequenced and comparative analyses were performed on the vision-related and olfactory receptor (or) genes to understand the molecular mechanisms of the visual and olfactory adaptation of night herons. |
2022-10-03 |
2023-08-14 |
Not clear |
| Xiao-Bin Fan, Bao-Tong Mo, Guo-Cheng Li, Ling-Qiao Huang, Hao Guo, Xin-Lin Gong, Chen-Zhu Wan. Mutagenesis of the odorant receptor co-receptor (Orco) reveals severe olfactory defects in the crop pest moth Helicoverpa armigera. BMC biology. vol 20. issue 1. 2022-09-29. PMID:36175945. |
other types of olfactory receptor proteins, such as ionotropic receptors (irs) and some gustatory receptors (grs), are also involved in the olfactory system of insects. |
2022-09-29 |
2023-08-14 |
Not clear |
| Motoki Yasunaga, Eiji Takai, Shoji Hattori, Kenji Tatematsu, Shun'ichi Kurod. Effects of 3-octen-2-one on human olfactory receptor responses to vanilla flavor. Bioscience, biotechnology, and biochemistry. 2022-09-08. PMID:36073350. |
in this study, to understand the interaction between odor molecules at the level of human olfactory receptor responses, the effects of 3-octen-2-one, which has been shown to modulate vanilla flavors, were analyzed using a human olfactory receptor sensor that uses all human olfactory receptors (388 types) as sensing molecules. |
2022-09-08 |
2023-08-14 |
human |
| Kevin W Zhu, Shawn D Burton, Maira H Nagai, Justin D Silverman, Claire A de March, Matt Wachowiak, Hiroaki Matsunam. Decoding the olfactory map through targeted transcriptomics links murine olfactory receptors to glomeruli. Nature communications. vol 13. issue 1. 2022-09-01. PMID:36050313. |
sensory processing in olfactory systems is organized across olfactory bulb glomeruli, wherein axons of peripheral sensory neurons expressing the same olfactory receptor co-terminate to transmit receptor-specific activity to central neurons. |
2022-09-01 |
2023-08-14 |
mouse |
| Richard L Dot. Olfactory dysfunction in COVID-19: pathology and long-term implications for brain health. Trends in molecular medicine. 2022-07-09. PMID:35810128. |
this review explores what is presently known about the nature and pathophysiology of olfactory dysfunction due to the sars-cov-2 virus, including reversible inflammation within the olfactory cleft, downregulation of olfactory receptor proteins, and long-lasting peripheral and central damage to olfactory structures. |
2022-07-09 |
2023-08-14 |
Not clear |
| Wei Han, Yiran Wu, Liting Zeng, Suwen Zha. Building the Chordata Olfactory Receptor Database using more than 400,000 receptors annotated by Genome2OR. Science China. Life sciences. 2022-06-13. PMID:35696018. |
in total, 765,248 olfactory receptor genes were annotated, with 404,426 functional genes and 360,822 pseudogenes, which represents a four-fold increase in the number of annotated olfactory receptors. |
2022-06-13 |
2023-08-14 |
Not clear |
| Nora Laseca, Antonio Molina, Mercedes Valera, Alicia Antonini, Sebastián Demyda-Peyrá. Copy Number Variation (CNV): A New Genomic Insight in Horses. Animals : an open access journal from MDPI. vol 12. issue 11. 2022-06-10. PMID:35681904. |
our results showed that 71.4% of cnvrs contained genes involved in olfactory transduction, olfactory receptor activity, and immune response. |
2022-06-10 |
2023-08-14 |
Not clear |
| Alvin V Terry, Wayne D Beck, Ping-Chang Lin, Patrick M Callahan, R Daniel Rudic, Mark W Hamric. Manganese-enhanced magnetic resonance imaging method detects age-related impairments in axonal transport in mice and attenuation of the impairments by a microtubule-stabilizing compound. Brain research. 2022-05-21. PMID:35597325. |
in this study a manganese-enhanced magnetic resonance imaging (memri) method was developed for mice for measuring axonal transport (axt) rates in real time in olfactory receptor neurons, which project from the olfactory epithelium to the olfactory neuronal layer of the olfactory bulb. |
2022-05-21 |
2023-08-13 |
mouse |
| Zhongyi Cui, Yipeng Liu, Guirong Wang, Qiong Zho. Identification and functional analysis of a chemosensory protein from Bactrocera minax (Diptera: Tephritidae). Pest management science. 2022-05-14. PMID:35567397. |
chemosensory proteins (csps) function to screen external odorants and transport them to olfactory receptor neurons (orns), thereby increasing the sensitivity of the olfactory system. |
2022-05-14 |
2023-08-13 |
Not clear |
| Daniel Kowatschew, Sigrun I Korschin. Lamprey possess both V1R and V2R olfactory receptors, but only V1Rs are expressed in olfactory sensory neurons. Chemical senses. vol 47. 2022-05-06. PMID:35522082. |
however, lamprey v2r genes appear not to have acquired an olfactory function yet, thus dissociating the evolutionary origin of the family from the onset of a function as olfactory receptor. |
2022-05-06 |
2023-08-13 |
Not clear |
| Laura Ziuzia-Januszewska, Marcin Januszewsk. Pathogenesis of Olfactory Disorders in COVID-19. Brain sciences. vol 12. issue 4. 2022-04-21. PMID:35447981. |
several theories have been proposed to explain the pathogenesis of covid-19-related anosmia, including nasal obstruction and rhinorrhea, oedema of the olfactory cleft mucosa, olfactory epithelial damage either within the olfactory receptor cells or the supporting non-neural cells (either direct or immune-mediated), damage to the olfactory bulb, and impairment of the central olfactory pathways. |
2022-04-21 |
2023-08-13 |
Not clear |
| Jian Zhang, Chi Huang, Guiqi Zhu, Guanyi He, Wenbo Xu, Jianming Li, Dong Wang, Kecheng Han, Zilong Shen, Jianyu Li. Selection of lncRNAs That Influence the Prognosis of Osteosarcoma Based on Copy Number Variation Data. Journal of oncology. vol 2022. 2022-04-05. PMID:35378771. |
gene ontology (go) and kyoto encyclopedia of gene and genome (kegg) pathway enrichment analyses revealed that these mrnas were mainly enriched in olfaction, olfactory receptor activity, and olfactory transduction processes. |
2022-04-05 |
2023-08-13 |
Not clear |
| Aurora Kraus, Mar Huertas, Laura Ellis, Pierre Boudinot, Jean-Pierre Levraud, Irene Salina. Intranasal delivery of SARS-CoV-2 Spike protein is sufficient to cause olfactory damage, inflammation and olfactory dysfunction in zebrafish. Brain, behavior, and immunity. 2022-03-21. PMID:35307504. |
single cell rna-seq of the adult zebrafish olfactory organ indicated widespread loss of olfactory receptor expression and inflammatory responses in sustentacular, endothelial, and myeloid cell clusters along with reduced numbers of t |
2022-03-21 |
2023-08-13 |
zebrafish |
| Zheng-Lin Yu, Jie Feng, Hao Song, Mei-Jie Yang, Zhi Hu, Cong Zhou, Pu Shi, Xiu-Tang Yuan, Hai-Zhou Li, Tao Zhang, Lei Li. Identification and characterization of olfactory receptor genes and olfactory perception in rapa whelk Rapana venosa (Valenciennes, 1846) during larval settlement and metamorphosis. Gene. 2022-03-20. PMID:35306113. |
identification and characterization of olfactory receptor genes and olfactory perception in rapa whelk rapana venosa (valenciennes, 1846) during larval settlement and metamorphosis. |
2022-03-20 |
2023-08-13 |
Not clear |