| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ping Jun Zhu, David M Lovinge. Retrograde endocannabinoid signaling in a postsynaptic neuron/synaptic bouton preparation from basolateral amygdala. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 26. 2006-02-14. PMID:15987949. |
in the basolateral amygdala (bla), endocannabinoid signaling has been implicated in learning and memory, specifically in extinction of aversive memories. |
2006-02-14 |
2023-08-12 |
Not clear |
| A Bilkei-Gorzo, I Racz, O Valverde, M Otto, K Michel, M Sastre, M Sarstre, A Zimme. Early age-related cognitive impairment in mice lacking cannabinoid CB1 receptors. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 43. 2005-12-12. PMID:16221768. |
we demonstrate here that young mice (6-7 weeks) with a genetic deletion of the cannabinoid cb1 receptor performed as well as wt mice, or often better, in a number of learning and memory paradigms, including animal models of skill-learning, partner recognition, and operant conditioning. |
2005-12-12 |
2023-08-12 |
mouse |
| Reinaldo Naoto Takahashi, Fabrício Alano Pamplona, Marcelo Soares Fernande. The cannabinoid antagonist SR141716A facilitates memory acquisition and consolidation in the mouse elevated T-maze. Neuroscience letters. vol 380. issue 3. 2005-07-20. PMID:15862900. |
the high concentration of cannabinoid cb1 receptors and the presence of endocannabinoids in the hippocampus suggest that a cannabinoid neurochemical system may play a role in learning and memory processes. |
2005-07-20 |
2023-08-12 |
mouse |
| Y Sarne, O Kere. Are cannabinoid drugs neurotoxic or neuroprotective? Medical hypotheses. vol 63. issue 2. 2005-02-24. PMID:15236773. |
chronic exposure to cannabinoids was shown to induce long lasting impairment of learning and memory, which was accompanied by morphological damage to the brain. |
2005-02-24 |
2023-08-12 |
Not clear |
| David J Rademacher, Daniel N Weber, Cecilia J Hillar. Waterborne lead exposure affects brain endocannabinoid content in male but not female fathead minnows (Pimephales promelas). Neurotoxicology. vol 26. issue 1. 2005-01-11. PMID:15527869. |
moreover, pb2+ exposure produces learning and memory impairments as do the cannabinoids. |
2005-01-11 |
2023-08-12 |
rat |
| Aldemar Degroot, George G Nomiko. Genetic deletion and pharmacological blockade of CB1 receptors modulates anxiety in the shock-probe burying test. The European journal of neuroscience. vol 20. issue 4. 2004-10-14. PMID:15305874. |
cannabinoids affect various behavioral processes, including emotion, learning and memory, which may be specifically regulated through the cb1 receptors. |
2004-10-14 |
2023-08-12 |
mouse |
| Piotr Kosiorek, Anna Hryniewicz, Izabela Bialuk, Agnieszka Zawadzka, Maria M Winnick. Cannabinoids alter recognition memory in rats. Polish journal of pharmacology. vol 55. issue 5. 2004-06-10. PMID:14704485. |
cannabinoids are known to attenuate learning and memory in both humans and animals. |
2004-06-10 |
2023-08-12 |
mouse |
| George Lees, Antonios Dougali. Differential effects of the sleep-inducing lipid oleamide and cannabinoids on the induction of long-term potentiation in the CA1 neurons of the rat hippocampus in vitro. Brain research. vol 997. issue 1. 2004-03-29. PMID:14715144. |
cannabinoids have been shown to impair cognition in vivo and block long-term potentiation (ltp), a candidate experimental model of learning and memory in vitro, via cannabinoid receptor (cb1) activation. |
2004-03-29 |
2023-08-12 |
rat |
| Andrew J Irving, Mark G Rae, Angela A Coutt. Cannabinoids on the brain. TheScientificWorldJournal. vol 2. 2004-03-23. PMID:12805989. |
cannabinoids have widespread actions in the brain: in the hippocampus they influence learning and memory; in the basal ganglia they modulate locomotor activity and reward pathways; in the hypothalamus they have a role in the control of appetite. |
2004-03-23 |
2023-08-12 |
Not clear |
| Vivien Chevaleyre, Pablo E Castill. Heterosynaptic LTD of hippocampal GABAergic synapses: a novel role of endocannabinoids in regulating excitability. Neuron. vol 38. issue 3. 2003-06-10. PMID:12741992. |
this heterosynaptic form of plasticity is involved in changes of pyramidal cell excitability associated with long-term potentiation at excitatory synapses and could account for the effects of cannabinoids on learning and memory. |
2003-06-10 |
2023-08-12 |
Not clear |
| Roberto Ciccocioppo, Lorena Antonelli, Michela Biondini, Marina Perfumi, Pierluigi Pompei, Maurizio Mass. Memory impairment following combined exposure to delta(9)-tetrahydrocannabinol and ethanol in rats. European journal of pharmacology. vol 449. issue 3. 2003-02-13. PMID:12167466. |
since both ethanol and cannabinoids are known to impair learning and memory, the present study investigated in rats the effects of combined exposure to ethanol and delta(9)-tetrahydrocannabinol (thc) in a memory task, the object recognition test. |
2003-02-13 |
2023-08-12 |
rat |
| S N Davies, R G Pertwee, G Riede. Functions of cannabinoid receptors in the hippocampus. Neuropharmacology. vol 42. issue 8. 2002-10-11. PMID:12128000. |
cannabinoids have consistently been reported to inhibit high frequency stimulation induced synaptic long-term potentiation but the experimental design of most behavioural experiments have meant it is not possible to categorically demonstrate a role for hippocampal cannabinoid receptors in learning and memory. |
2002-10-11 |
2023-08-12 |
human |
| Miquel Martin, Catherine Ledent, Marc Parmentier, Rafael Maldonado, Olga Valverd. Involvement of CB1 cannabinoid receptors in emotional behaviour. Psychopharmacology. vol 159. issue 4. 2002-04-09. PMID:11823890. |
endogenous and exogenous cannabinoids acting through the cb1 cannabinoid receptors are implicated in the control of a variety of behavioural and neuroendocrine functions, including emotional responses, and learning and memory processes. |
2002-04-09 |
2023-08-12 |
mouse |
| M C Beinfeld, K Connoll. Activation of CB1 cannabinoid receptors in rat hippocampal slices inhibits potassium-evoked cholecystokinin release, a possible mechanism contributing to the spatial memory defects produced by cannabinoids. Neuroscience letters. vol 301. issue 1. 2001-06-07. PMID:11239718. |
cannabinoid use is known to disrupt learning and memory in a number of species. |
2001-06-07 |
2023-08-12 |
rat |
| J Lawston, A Borella, J K Robinson, P M Whitaker-Azmiti. Changes in hippocampal morphology following chronic treatment with the synthetic cannabinoid WIN 55,212-2. Brain research. vol 877. issue 2. 2000-12-14. PMID:10986361. |
like tetrahydrocannabinol (thc) itself, many synthetic cannabinoids such as the cb-1 receptor agonist win 55,212-2 will induce learning and memory changes. |
2000-12-14 |
2023-08-12 |
rat |
| J M Sulliva. Cellular and molecular mechanisms underlying learning and memory impairments produced by cannabinoids. Learning & memory (Cold Spring Harbor, N.Y.). vol 7. issue 3. 2000-08-01. PMID:10837502. |
cellular and molecular mechanisms underlying learning and memory impairments produced by cannabinoids. |
2000-08-01 |
2023-08-12 |
Not clear |
| J M Sulliva. Cellular and molecular mechanisms underlying learning and memory impairments produced by cannabinoids. Learning & memory (Cold Spring Harbor, N.Y.). vol 7. issue 3. 2000-08-01. PMID:10837502. |
these mechanisms likely play a role in the learning and memory impairments produced by cannabinoids and by endogenous cannabinoid receptor ligands. |
2000-08-01 |
2023-08-12 |
Not clear |
| G Marsicano, B Lut. Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain. The European journal of neuroscience. vol 11. issue 12. 2000-02-10. PMID:10594647. |
cannabinoids can modulate motor behaviour, learning and memory, cognition and pain perception. |
2000-02-10 |
2023-08-12 |
mouse |
| G A Bohme, M Laville, C Ledent, M Parmentier, A Imperat. Enhanced long-term potentiation in mice lacking cannabinoid CB1 receptors. Neuroscience. vol 95. issue 1. 2000-01-31. PMID:10619457. |
marijuana is known to affect learning and memory in humans, and cannabinoids block long-term potentiation in the hippocampus, a model for the synaptic changes that are believed to underlie memory at the cellular level. |
2000-01-31 |
2023-08-12 |
mouse |
| B E Akinshola, R E Taylor, A B Ogunseitan, E S Onaiv. Anandamide inhibition of recombinant AMPA receptor subunits in Xenopus oocytes is increased by forskolin and 8-bromo-cyclic AMP. Naunyn-Schmiedeberg's archives of pharmacology. vol 360. issue 3. 1999-12-03. PMID:10543424. |
because anandamide does inhibit long-term potentiation, and cannabinoid abuse is known to affect learning and memory, the effects of anandamide on recombinant ampa glutamate receptor (glur) subunit currents were studied in xenopus oocytes. |
1999-12-03 |
2023-08-12 |
xenopus_laevis |