| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J M Petitto, R K McNamara, P L Gendreau, Z Huang, A J Jackso. Impaired learning and memory and altered hippocampal neurodevelopment resulting from interleukin-2 gene deletion. Journal of neuroscience research. vol 56. issue 4. 1999-07-15. PMID:10340751. |
the spatial learning and memory impairment in il-2 knockout mice was accompanied by reductions in hippocampal infrapyramidal mossy neuronal fiber length, a factor shown previously to correlate positively with spatial learning ability. |
1999-07-15 |
2023-08-12 |
mouse |
| T Koyama, Y Nakajima, T Fujii, K Kawashim. Enhancement of cortical and hippocampal cholinergic neurotransmission through 5-HT1A receptor-mediated pathways by BAY x 3702 in freely moving rats. Neuroscience letters. vol 265. issue 1. 1999-07-14. PMID:10327199. |
cortical and hippocampal cholinergic neurotransmission is of particular importance in the mechanisms of attention as well as learning and memory. |
1999-07-14 |
2023-08-12 |
rat |
| J D Bremne. Does stress damage the brain? Biological psychiatry. vol 45. issue 7. 1999-06-14. PMID:10202566. |
studies in animals showed that stress results in damage to the hippocampus, a brain area involved in learning and memory, with associated memory deficits. |
1999-06-14 |
2023-08-12 |
Not clear |
| F Engert, T Bonhoeffe. Dendritic spine changes associated with hippocampal long-term synaptic plasticity. Nature. vol 399. issue 6731. 1999-06-14. PMID:10331391. |
long-term enhancement of synaptic efficacy in the hippocampus is an important model for studying the cellular mechanisms of neuronal plasticity, circuit reorganization, and even learning and memory. |
1999-06-14 |
2023-08-12 |
Not clear |
| Y Zhao, H Z Sheng, R Amini, A Grinberg, E Lee, S Huang, M Taira, H Westpha. Control of hippocampal morphogenesis and neuronal differentiation by the LIM homeobox gene Lhx5. Science (New York, N.Y.). vol 284. issue 5417. 1999-06-08. PMID:10325223. |
the mammalian hippocampus contains the neural circuitry that is crucial for cognitive functions such as learning and memory. |
1999-06-08 |
2023-08-12 |
mouse |
| S A Rubin, P Sylves, M Vogel, M Pletnikov, T H Moran, G J Schwartz, K M Carbon. Borna disease virus-induced hippocampal dentate gyrus damage is associated with spatial learning and memory deficits. Brain research bulletin. vol 48. issue 1. 1999-06-03. PMID:10210164. |
borna disease virus-induced hippocampal dentate gyrus damage is associated with spatial learning and memory deficits. |
1999-06-03 |
2023-08-12 |
rat |
| S A Rubin, P Sylves, M Vogel, M Pletnikov, T H Moran, G J Schwartz, K M Carbon. Borna disease virus-induced hippocampal dentate gyrus damage is associated with spatial learning and memory deficits. Brain research bulletin. vol 48. issue 1. 1999-06-03. PMID:10210164. |
our data demonstrate progressive spatial learning and memory deficits in bdv-infected rats that coincided with a gradual decline in the estimated hippocampal dentate gyrus neuron density. |
1999-06-03 |
2023-08-12 |
rat |
| L Korb. Glial cell loss in the hippocampus of alcoholics. Alcoholism, clinical and experimental research. vol 23. issue 1. 1999-06-01. PMID:10029219. |
hippocampus is an area of the brain primarily involved in learning and memory, and the hippocampus is affected in several demential diseases. |
1999-06-01 |
2023-08-12 |
Not clear |
| N S Clayto. Memory and the hippocampus in food-storing birds: a comparative approach. Neuropharmacology. vol 37. issue 4-5. 1999-05-26. PMID:9704985. |
comparative studies provide a unique source of evidence for the role of the hippocampus in learning and memory. |
1999-05-26 |
2023-08-12 |
Not clear |
| J A Oler, E J Marku. Age-related deficits on the radial maze and in fear conditioning: hippocampal processing and consolidation. Hippocampus. vol 8. issue 4. 1999-05-18. PMID:9744425. |
finally, the implications of such age-related changes in hippocampal consolidation on learning and memory are discussed. |
1999-05-18 |
2023-08-12 |
rat |
| M E Calhoun, D Kurth, A L Phinney, J M Long, J Hengemihle, P R Mouton, D K Ingram, M Jucke. Hippocampal neuron and synaptophysin-positive bouton number in aging C57BL/6 mice. Neurobiology of aging. vol 19. issue 6. 1999-05-11. PMID:10192220. |
a loss of hippocampal neurons and synapses had been considered a hallmark of normal aging and, furthermore, to be a substrate of age-related learning and memory deficits. |
1999-05-11 |
2023-08-12 |
mouse |
| A Parent, D J Linden, S S Sisodia, D R Borchel. Synaptic transmission and hippocampal long-term potentiation in transgenic mice expressing FAD-linked presenilin 1. Neurobiology of disease. vol 6. issue 1. 1999-05-06. PMID:10078973. |
to examine whether fad-linked mutations in ps1 directly influence the physiology of learning and memory, we measured the field excitatory postsynaptic potential (fepsp) at the schaffer collateral-ca1 synapse in hippocampal slices. |
1999-05-06 |
2023-08-12 |
mouse |
| E A Murray, M G Baxter, D Gaffa. Monkeys with rhinal cortex damage or neurotoxic hippocampal lesions are impaired on spatial scene learning and object reversals. Behavioral neuroscience. vol 112. issue 6. 1999-04-30. PMID:9926813. |
rhesus monkeys (macaca mulatta) with lesions of the rhinal cortex or parahippocampal gyrus (made by aspiration) or hippocampus (made with ibotenic acid) and unoperated controls were tested on object discrimination and reversal, place discrimination and reversal, and spatial scene learning to determine the contribution of these temporal lobe structures to these forms of learning and memory. |
1999-04-30 |
2023-08-12 |
monkey |
| C M Atkins, J C Selcher, J J Petraitis, J M Trzaskos, J D Sweat. The MAPK cascade is required for mammalian associative learning. Nature neuroscience. vol 1. issue 7. 1999-04-29. PMID:10196568. |
recently mapk activation in post-mitotic cells has been implicated in hippocampal long-term potentiation (ltp), a potential cellular mechanism of learning and memory. |
1999-04-29 |
2023-08-12 |
rat |
| D Young, P A Lawlor, P Leone, M Dragunow, M J Durin. Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective. Nature medicine. vol 5. issue 4. 1999-04-29. PMID:10202938. |
one of the most robust associations of environmental enrichment is improved learning and memory in the morris water maze, a spatial task that mainly involves the hippocampus. |
1999-04-29 |
2023-08-12 |
rat |
| S J Lupien, M de Leon, S de Santi, A Convit, C Tarshish, N P Nair, M Thakur, B S McEwen, R L Hauger, M J Meane. Cortisol levels during human aging predict hippocampal atrophy and memory deficits. Nature neuroscience. vol 1. issue 1. 1999-04-21. PMID:10195112. |
therefore, basal cortisol elevation may cause hippocampal damage and impair hippocampus-dependent learning and memory in humans. |
1999-04-21 |
2023-08-12 |
human |
| C D Albright, A Y Tsai, C B Friedrich, M H Mar, S H Zeise. Choline availability alters embryonic development of the hippocampus and septum in the rat. Brain research. Developmental brain research. vol 113. issue 1-2. 1999-04-07. PMID:10064869. |
these results show that dietary choline availability alters the timing of the genesis, migration, and commitment to differentiation of progenitor neuronal-type cells in fetal brain hippocampal regions known to be associated with learning and memory processes in adult brain. |
1999-04-07 |
2023-08-12 |
rat |
| B Pouzet, H Welzl, M K Gubler, L Broersen, C L Veenman, J Feldon, J N Rawlins, B K Ye. The effects of NMDA-induced retrohippocampal lesions on performance of four spatial memory tasks known to be sensitive to hippocampal damage in the rat. The European journal of neuroscience. vol 11. issue 1. 1999-04-01. PMID:9987017. |
the present study demonstrated that unlike direct hippocampal damage, retrohippocampal cell loss did not lead to a general impairment in spatial learning, implying that the integrity of the retrohippocampus and/or its interconnection with the hippocampal formation is not critical for normal hippocampal-dependent spatial learning and memory. |
1999-04-01 |
2023-08-12 |
rat |
| B Alescio-Lautier, B Soumireu-Moura. Role of vasopressin in learning and memory in the hippocampus. Progress in brain research. vol 119. 1999-03-29. PMID:10074809. |
role of vasopressin in learning and memory in the hippocampus. |
1999-03-29 |
2023-08-12 |
mouse |
| B Alescio-Lautier, B Soumireu-Moura. Role of vasopressin in learning and memory in the hippocampus. Progress in brain research. vol 119. 1999-03-29. PMID:10074809. |
the involvement of arginine8-vasopressin (vp) in learning and memory in the hippocampus is examined in mice using a discriminative learning task. |
1999-03-29 |
2023-08-12 |
mouse |