| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jin-Ran Chen, Jian Zhang, Oxana P Lazarenko, Jay J Cao, Michael L Blackburn, Thomas M Badger, Martin J J Roni. Soy protein isolates prevent loss of bone quantity associated with obesity in rats through regulation of insulin signaling in osteoblasts. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 27. issue 9. 2013-11-12. PMID:23776073. |
these results suggest that high-fat feeding may disrupt bone development and modeling; high concentrations of nefas and insulin resistance occurring with high fat intake are mediators of reduced osteoblast activity and differentiation; diets high in soy protein may help prevent high dietary fat-induced bone impairments; and the molecular mechanisms underlying the spi-protective effects involve isoflavone-induced normalization of insulin signaling in bone. |
2013-11-12 |
2023-08-12 |
rat |
| Rasoul Ghasemi, Leila Dargahi, Ali Haeri, Maryam Moosavi, Zahurin Mohamed, Abolhassan Ahmadian. Brain insulin dysregulation: implication for neurological and neuropsychiatric disorders. Molecular neurobiology. vol 47. issue 3. 2013-11-11. PMID:23335160. |
a growing number of evidences show that insulin is involved in several physiological function of the brain such as food intake and weight control, reproduction, learning and memory, neuromodulation and neuroprotection. |
2013-11-11 |
2023-08-12 |
Not clear |
| Thomas Scherer, Hendrik Lehnert, Manfred Hallschmi. Brain insulin and leptin signaling in metabolic control: from animal research to clinical application. Endocrinology and metabolism clinics of North America. vol 42. issue 1. 2013-11-07. PMID:23391243. |
besides the well-characterized effects of brain insulin and leptin in regulating food intake, insulin and leptin signaling to the central nervous system modulates a variety of metabolic processes, such as glucose and lipid homeostasis, as well as energy expenditure. |
2013-11-07 |
2023-08-12 |
Not clear |
| Shanmugam Muthulakshmi, Ramalingam Saravana. Efficacy of azelaic acid on hepatic key enzymes of carbohydrate metabolism in high fat diet induced type 2 diabetic mice. Biochimie. vol 95. issue 6. 2013-11-07. PMID:23402910. |
body weight, food intake, plasma glucose, plasma insulin, blood haemoglobin (hb), blood glycosylated haemoglobin (hba1c), liver glycolytic enzyme (hexokinase), hepatic shunt enzyme (glucose-6-phosphate dehydrogenase), gluconeogenic enzymes(glucose-6-phosphatase and fructose-1,6-bisphosphatase), liver glycogen, plasma and liver triglycerides were examined in mice fed with normal standard diet (nc), high fat diet (hfd), hfd with aza (hfd + aza) and hfd with rosiglitazone (hfd + rsg). |
2013-11-07 |
2023-08-12 |
mouse |
| b' Andreas Stengel, Miriam Goebel-Stengel, Lixin Wang, Eugenia Hu, Hiroshi Karasawa, Joseph R Pisegna, Yvette Tach\\xc3\\xa. High-protein diet selectively reduces fat mass and improves glucose tolerance in Western-type diet-induced obese rats. American journal of physiology. Regulatory, integrative and comparative physiology. vol 305. issue 6. 2013-11-05. PMID:23883680.' |
food intake (fi), bw, body composition, glucose tolerance, insulin sensitivity, and intestinal hormone plasma levels were monitored. |
2013-11-05 |
2023-08-12 |
rat |
| Sophie Carter, Alexandre Caron, Denis Richard, Frédéric Picar. Role of leptin resistance in the development of obesity in older patients. Clinical interventions in aging. vol 8. 2013-11-04. PMID:23869170. |
centrally, leptin controls food intake, energy expenditure, and fat distribution, whereas it controls (among several others) insulin sensitivity, free fatty acids (ffas) oxidation, and lipolysis in the periphery. |
2013-11-04 |
2023-08-12 |
Not clear |
| Eva-Lena Stenblom, Caroline Montelius, Karolina Östbring, Maria Håkansson, Sofia Nilsson, Jens F Rehfeld, Charlotte Erlanson-Albertsso. Supplementation by thylakoids to a high carbohydrate meal decreases feelings of hunger, elevates CCK levels and prevents postprandial hypoglycaemia in overweight women. Appetite. vol 68. 2013-10-29. PMID:23632035. |
it has been previously shown that thylakoids supplemented with a high-fat meal can affect cholecystokinin (cck), ghrelin, insulin and blood lipids in humans, and can act to suppress food intake and prevent body weight gain in rodents. |
2013-10-29 |
2023-08-12 |
human |
| Susumu Hirabayashi, Thomas J Baranski, Ross L Caga. Transformed Drosophila cells evade diet-mediated insulin resistance through wingless signaling. Cell. vol 154. issue 3. 2013-10-28. PMID:23911328. |
feeding drosophila a diet high in carbohydrates was previously demonstrated to direct metabolic dysfunction, including hyperglycemia, hyperinsulinemia, and insulin resistance. |
2013-10-28 |
2023-08-12 |
drosophila_melanogaster |
| Hong-Kui Wei, Yuanfei Zhou, Shuzhong Jiang, Ya-Xiong Tao, Haiqing Sun, Jian Peng, Siwen Jian. Feeding a DHA-enriched diet increases skeletal muscle protein synthesis in growing pigs: association with increased skeletal muscle insulin action and local mRNA expression of insulin-like growth factor 1. The British journal of nutrition. vol 110. issue 4. 2013-10-21. PMID:23433177. |
feeding a dha-enriched diet increases skeletal muscle protein synthesis in growing pigs: association with increased skeletal muscle insulin action and local mrna expression of insulin-like growth factor 1. |
2013-10-21 |
2023-08-12 |
Not clear |
| Hong-Kui Wei, Yuanfei Zhou, Shuzhong Jiang, Ya-Xiong Tao, Haiqing Sun, Jian Peng, Siwen Jian. Feeding a DHA-enriched diet increases skeletal muscle protein synthesis in growing pigs: association with increased skeletal muscle insulin action and local mRNA expression of insulin-like growth factor 1. The British journal of nutrition. vol 110. issue 4. 2013-10-21. PMID:23433177. |
feeding the de diet increased muscle insulin-like growth factor 1 (igf-1) expression (p<0·05) and insulin action (as demonstrated by increased insulin receptor (ir) phosphorylation, p<0·05), resulting in increased ir substrate 1 activation in the fed state. |
2013-10-21 |
2023-08-12 |
Not clear |
| Hong-Kui Wei, Yuanfei Zhou, Shuzhong Jiang, Ya-Xiong Tao, Haiqing Sun, Jian Peng, Siwen Jian. Feeding a DHA-enriched diet increases skeletal muscle protein synthesis in growing pigs: association with increased skeletal muscle insulin action and local mRNA expression of insulin-like growth factor 1. The British journal of nutrition. vol 110. issue 4. 2013-10-21. PMID:23433177. |
the results of the present study suggest that feeding a de diet increased feeding-induced muscle protein synthesis in growing pigs, and muscle igf-1 expression and insulin action were involved in this action. |
2013-10-21 |
2023-08-12 |
Not clear |
| Michael S F Wiedemann, Stephan Wueest, Flurin Item, Eugen J Schoenle, Daniel Konra. Adipose tissue inflammation contributes to short-term high-fat diet-induced hepatic insulin resistance. American journal of physiology. Endocrinology and metabolism. vol 305. issue 3. 2013-10-17. PMID:23736545. |
high-fat feeding for 3-4 days impairs glucose tolerance and hepatic insulin sensitivity. |
2013-10-17 |
2023-08-12 |
mouse |
| Michael S F Wiedemann, Stephan Wueest, Flurin Item, Eugen J Schoenle, Daniel Konra. Adipose tissue inflammation contributes to short-term high-fat diet-induced hepatic insulin resistance. American journal of physiology. Endocrinology and metabolism. vol 305. issue 3. 2013-10-17. PMID:23736545. |
in the present study, feeding c57bl6/j mice a fat-enriched diet [high-fat diet (hfd)] for 4 days induced glucose intolerance, hepatic insulin resistance (as assessed by hyperinsulinemic euglycemic clamp studies), and hepatic steatosis as well as adipose tissue inflammation (i.e., tnfα expression) compared with standard chow-fed mice. |
2013-10-17 |
2023-08-12 |
mouse |
| Stephanie Venn-Watson, Cynthia Rowe Smith, Sacha Stevenson, Celeste Parry, Risa Daniels, Eric Jensen, Veronica Cendejas, Brian Balmer, Michael Janech, Benjamin A Neely, Randall Well. Blood-Based Indicators of Insulin Resistance and Metabolic Syndrome in Bottlenose Dolphins (Tursiops truncatus). Frontiers in endocrinology. vol 4. 2013-10-16. PMID:24130551. |
future investigations with these two dolphin populations, including dietary and feeding differences, may provide valuable insight for preventing and treating insulin resistance in humans. |
2013-10-16 |
2023-08-12 |
Not clear |
| Ana Ortega-Molina, Manuel Serran. PTEN in cancer, metabolism, and aging. Trends in endocrinology and metabolism: TEM. vol 24. issue 4. 2013-09-23. PMID:23245767. |
pten transgenic mice present increased energy expenditure, decreased adiposity, improved insulin sensitivity upon high-fat feeding or with aging, and extended lifespan. |
2013-09-23 |
2023-08-12 |
mouse |
| U Schönhusen, P Junghans, A Flöter, J Steinhoff-Wagner, S Görs, F Schneider, C C Metges, H M Hammo. First-pass uptake and oxidation of glucose by the splanchnic tissue in young goats fed soy protein-based milk diets with or without amino acid supplementation: glucose metabolism in goat kids after soy feeding. Journal of dairy science. vol 96. issue 4. 2013-09-23. PMID:23415525. |
plasma glucose and insulin concentrations increased during the first hour after feeding, whereas plasma glucagon increased immediately after feeding and after 1h of feeding. |
2013-09-23 |
2023-08-12 |
Not clear |
| H M Hammon, J Steinhoff-Wagner, J Flor, U Schönhusen, C C Metge. Lactation Biology Symposium: role of colostrum and colostrum components on glucose metabolism in neonatal calves. Journal of animal science. vol 91. issue 2. 2013-09-17. PMID:23100594. |
although colostrum feeding affects systemic insulin, igf-i, and leptin concentrations, evidence for systemic action of colostral insulin, igf-i, and leptin in neonatal calves is weak. |
2013-09-17 |
2023-08-12 |
Not clear |
| Michael A Lomax, Georgios Karamanlidis, John Laws, Stephanie G Cremers, Peter D Weinberg, Lynne Clark. Pigs fed saturated fat/cholesterol have a blunted hypothalamic-pituitary-adrenal function, are insulin resistant and have decreased expression of IRS-1, PGC1α and PPARα. The Journal of nutritional biochemistry. vol 24. issue 4. 2013-09-16. PMID:22819557. |
we conclude that feeding increased saturated fat to pigs causes disruption in the hpa axis, insulin resistance and decreased muscle and adipose expression of genes controlling insulin signalling and mitochondrial oxidative capacity. |
2013-09-16 |
2023-08-12 |
Not clear |
| Y Ichihara, T Wada, Y Soeda, Y Ishii, M Sasahara, H Tsuneki, T Sasaok. SH2-containing inositol 5'-phosphatase 2 selectively impairs hypothalamic insulin signalling and regulation of food intake in mice. Journal of neuroendocrinology. vol 25. issue 4. 2013-09-16. PMID:23286299. |
sh2-containing inositol 5'-phosphatase 2 selectively impairs hypothalamic insulin signalling and regulation of food intake in mice. |
2013-09-16 |
2023-08-12 |
mouse |
| Y Ichihara, T Wada, Y Soeda, Y Ishii, M Sasahara, H Tsuneki, T Sasaok. SH2-containing inositol 5'-phosphatase 2 selectively impairs hypothalamic insulin signalling and regulation of food intake in mice. Journal of neuroendocrinology. vol 25. issue 4. 2013-09-16. PMID:23286299. |
these results suggest that ship2 contributes to the regulation of food intake mainly via the attenuation of insulin signalling in the hypothalamus of mice. |
2013-09-16 |
2023-08-12 |
mouse |