| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ru-Jiang Li, Shu-Dong Qiu, Hong Tian, Sheng-Wei Zho. [Diabetes induced by multiple low doses of STZ can be spontaneously recovered in adult mice]. Dong wu xue yan jiu = Zoological research. vol 34. issue 3. 2014-04-07. PMID:23776001. |
by the week 36, although body weight and β cell masses remained significantly different between the mld-stz mice and the age-matched control animals, food intake, water consumption, blood glucose levels and serum insulin concentrations had all returned to normal levels, and no lymphocytic infiltrations were observed in pancreatic islets. |
2014-04-07 |
2023-08-12 |
mouse |
| Ya-Yen Chen, Ming-Hoang Lai, Hsin-Yu Hung, Jen-Fang Li. Sweet potato [Ipomoea batatas (L.) Lam. "Tainong 57"] starch improves insulin sensitivity in high-fructose diet-fed rats by ameliorating adipocytokine levels, pro-inflammatory status, and insulin signaling. Journal of nutritional science and vitaminology. vol 59. issue 4. 2014-04-04. PMID:24064727. |
our results illustrated that sweet potato starch feeding for 4 wk can improve insulin sensitivity in insulin-resistant rats, possibly by improving the adipocytokine levels, pro-inflammatory status, and insulin signaling. |
2014-04-04 |
2023-08-12 |
rat |
| Baskaran Yogalakshmi, Saravanan Bhuvaneswari, S Sreeja, Carani Venkatraman Anuradh. Grape seed proanthocyanidins and metformin act by different mechanisms to promote insulin signaling in rats fed high calorie diet. Journal of cell communication and signaling. vol 8. issue 1. 2014-04-02. PMID:24026800. |
albino wistar rats were rendered insulin resistant by feeding a high fat-fructose diet (hffd). |
2014-04-02 |
2023-08-12 |
rat |
| Seung-Hwan Lee, Hu Huang, Kangduk Choi, Dae Ho Lee, Jianjian Shi, Tiemin Liu, Kwang Hoon Chun, Ji A Seo, Ines S Lima, Janice M Zabolotny, Lei Wei, Young-Bum Ki. ROCK1 isoform-specific deletion reveals a role for diet-induced insulin resistance. American journal of physiology. Endocrinology and metabolism. vol 306. issue 3. 2014-03-31. PMID:24326423. |
consistently, adipose-specific disruption of rock1 increased ir tyrosine phosphorylation in adipose tissue and modestly improved sensitivity to insulin in obese mice induced by high-fat feeding. |
2014-03-31 |
2023-08-12 |
mouse |
| Xuewei Zhu, Soonkyu Chung, Xin Bi, Chia-Chi Chuang, Amanda L Brown, Mingxia Liu, Jeongmin Seo, Helen Cuffe, Abraham K Gebre, Elena Boudyguina, John S Park. Myeloid cell-specific ABCA1 deletion does not worsen insulin resistance in HF diet-induced or genetically obese mouse models. Journal of lipid research. vol 54. issue 10. 2014-03-28. PMID:23894207. |
myeloid cell-specific abca1 knockout (msko) and wild-type (wt) mice developed obesity, insulin resistance, mild hypercholesterolemia, and hepatic steatosis to a similar extent with a 45% high-fat (hf) diet feeding or after crossing into the ob/ob background. |
2014-03-28 |
2023-08-12 |
mouse |
| Seoyoon Choi, Youngshim Choi, Yeji Choi, Sohee Kim, Jeehee Jang, Taesun Par. Piperine reverses high fat diet-induced hepatic steatosis and insulin resistance in mice. Food chemistry. vol 141. issue 4. 2014-03-28. PMID:23993530. |
this study examined the effect of piperine on hepatic steatosis and insulin resistance induced in mice by feeding a high-fat diet (hfd) for 13 weeks and elucidated potential underlying molecular mechanisms. |
2014-03-28 |
2023-08-12 |
mouse |
| Seoyoon Choi, Youngshim Choi, Yeji Choi, Sohee Kim, Jeehee Jang, Taesun Par. Piperine reverses high fat diet-induced hepatic steatosis and insulin resistance in mice. Food chemistry. vol 141. issue 4. 2014-03-28. PMID:23993530. |
also, elevated plasma concentrations of insulin and glucose and hepatic lipid levels induced by feeding a hfd were reversed in mice when they were administered piperine. |
2014-03-28 |
2023-08-12 |
mouse |
| Louise Grant, Kirsty D Shearer, Alicja Czopek, Emma K Lees, Carl Owen, Abdelali Agouni, James Workman, Cristina Martin-Granados, John V Forrester, Heather M Wilson, Nimesh Mody, Mirela Delibegovi. Myeloid-cell protein tyrosine phosphatase-1B deficiency in mice protects against high-fat diet and lipopolysaccharide-induced inflammation, hyperinsulinemia, and endotoxemia through an IL-10 STAT3-dependent mechanism. Diabetes. vol 63. issue 2. 2014-03-28. PMID:24186864. |
chronic inflammation induced by high-fat (hf) feeding led to equally beneficial effects of macrophage ptp1b deficiency; lysm ptp1b mice exhibited improved glucose and insulin tolerance, protection against lps-induced hyperinsulinemia, decreased macrophage infiltration into adipose tissue, and decreased liver damage. |
2014-03-28 |
2023-08-12 |
mouse |
| P S Hogenkamp, J Cedernaes, C D Chapman, H Vogel, O C Hjorth, S Zarei, L S Lundberg, S J Brooks, S L Dickson, C Benedict, H B Schiöt. Calorie anticipation alters food intake after low-caloric not high-caloric preloads. Obesity (Silver Spring, Md.). vol 21. issue 8. 2014-03-24. PMID:23585292. |
the current study examined the effect of anticipation and actual consumption of food on hormone (ghrelin, cortisol, and insulin) and glucose levels, appetite and ad libitum intake, to assess whether changes in hormone levels might explain the predicted differences in subsequent food intake. |
2014-03-24 |
2023-08-12 |
Not clear |
| Ming Tong, Lisa Longato, Teresa Ramirez, Valerie Zabala, Jack R Wands, Suzanne M de la Mont. Therapeutic reversal of chronic alcohol-related steatohepatitis with the ceramide inhibitor myriocin. International journal of experimental pathology. vol 95. issue 1. 2014-03-18. PMID:24456332. |
in a rat model of chronic alcohol feeding, we characterized the effects of a ceramide inhibitor, myriocin, on the histopathological and ultrastructural features of steatohepatitis, and the biochemical and molecular indices of hepatic steatosis, insulin resistance and er stress. |
2014-03-18 |
2023-08-12 |
rat |
| Yutaka Mori, Teruo Ohta, Junichi Yokoyama, Kazunori Utsunomiy. Effects of low-carbohydrate/high-monounsaturated fatty acid liquid diets on diurnal glucose variability and insulin dose in type 2 diabetes patients on tube feeding who require insulin therapy. Diabetes technology & therapeutics. vol 15. issue 9. 2014-03-17. PMID:23931715. |
effects of low-carbohydrate/high-monounsaturated fatty acid liquid diets on diurnal glucose variability and insulin dose in type 2 diabetes patients on tube feeding who require insulin therapy. |
2014-03-17 |
2023-08-12 |
Not clear |
| Hongliang Li, Jiyeon Lee, Chaoyong He, Ming-Hui Zou, Zhonglin Xi. Suppression of the mTORC1/STAT3/Notch1 pathway by activated AMPK prevents hepatic insulin resistance induced by excess amino acids. American journal of physiology. Endocrinology and metabolism. vol 306. issue 2. 2014-03-14. PMID:24302004. |
finally, hpd feeding suppressed ampk activity, activated mtorc1/stat3/notch1 signaling, and induced insulin resistance. |
2014-03-14 |
2023-08-12 |
Not clear |
| Gábor Molnár, Nóra Faragó, Ágnes K Kocsis, Márton Rózsa, Sándor Lovas, Eszter Boldog, Rita Báldi, Éva Csajbók, János Gardi, László G Puskás, Gábor Tamá. GABAergic neurogliaform cells represent local sources of insulin in the cerebral cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 4. 2014-03-11. PMID:24453306. |
insulin in the brain regulates the metabolism, molecular composition, and cognitive performance of microcircuits and reduces food intake; cerebral insulin levels are altered in diabetes, aging, obesity, and alzheimer's disease. |
2014-03-11 |
2023-08-12 |
rat |
| Jing-Jing Zhou, Yan Wei, Li Zhang, Jiao Zhang, Lan-Ying Guo, Chao Gao, De-Pei Li, Yi Zhan. Chronic intermittent hypobaric hypoxia prevents cardiac dysfunction through enhancing antioxidation in fructose-fed rats. Canadian journal of physiology and pharmacology. vol 91. issue 5. 2014-03-05. PMID:23656204. |
in addition to an increase in blood pressure, fructose feeding caused elevated serum levels of glucose, fasting insulin and insulin c peptide, triglyceride, cholesterol, and mass ratio of heart to body. |
2014-03-05 |
2023-08-12 |
human |
| David Tarussio, Salima Metref, Pascal Seyer, Lourdes Mounien, David Vallois, Christophe Magnan, Marc Foretz, Bernard Thoren. Nervous glucose sensing regulates postnatal β cell proliferation and glucose homeostasis. The Journal of clinical investigation. vol 124. issue 1. 2014-03-03. PMID:24334455. |
these mice displayed normal energy homeostasis but developed late-onset glucose intolerance due to reduced insulin secretion, which was precipitated by high-fat diet feeding. |
2014-03-03 |
2023-08-12 |
mouse |
| Fenping Zheng, Yonwook J Kim, Pei-Ting Chao, Sheng B. Overexpression of neuropeptide Y in the dorsomedial hypothalamus causes hyperphagia and obesity in rats. Obesity (Silver Spring, Md.). vol 21. issue 6. 2014-02-28. PMID:23526718. |
we examined variables including body weight, food intake, energy efficiency, meal patterns, glucose tolerance, fat mass, plasma insulin, plasma leptin, and hypothalamic gene expression. |
2014-02-28 |
2023-08-12 |
rat |
| J Kutzner-Mulligan, J Eisemann, P Siciliano, J Smith, K Hewitt, J Sharlette, S Pratt-Phillip. The effect of different feed delivery methods on time to consume feed and the resulting changes in postprandial metabolite concentrations in horses. Journal of animal science. vol 91. issue 8. 2014-02-28. PMID:23739792. |
management techniques that reduce the insulin response to feeding in horses have application in preventing insulin resistance (ir) and potential associations (e.g., laminitis). |
2014-02-28 |
2023-08-12 |
human |
| J Kutzner-Mulligan, J Eisemann, P Siciliano, J Smith, K Hewitt, J Sharlette, S Pratt-Phillip. The effect of different feed delivery methods on time to consume feed and the resulting changes in postprandial metabolite concentrations in horses. Journal of animal science. vol 91. issue 8. 2014-02-28. PMID:23739792. |
glucose and insulin concentrations increased after feeding (p < 0.05) and tended to differ among treatments (p < 0.10). |
2014-02-28 |
2023-08-12 |
human |
| Geneviève Marcelin, Young-Hwan Jo, Xiaosong Li, Gary J Schwartz, Ying Zhang, Nae J Dun, Rong-Ming Lyu, Clémence Blouet, Jaw K Chang, Streamson Chu. Central action of FGF19 reduces hypothalamic AGRP/NPY neuron activity and improves glucose metabolism. Molecular metabolism. vol 3. issue 1. 2014-02-25. PMID:24567901. |
then, in two mouse models of insulin resistance, leptin-deficiency and high-fat diet feeding, third intra-cerebro-ventricular infusions of fgf19 improved glycemic status, reduced insulin resistance and potentiated insulin signaling in the periphery. |
2014-02-25 |
2023-08-12 |
mouse |
| Leontine E H Bakker, Linda D van Schinkel, Bruno Guigas, Trea C M Streefland, Jacqueline T Jonker, Jan B van Klinken, Gerard C M van der Zon, Hildo J Lamb, Johannes W A Smit, Hanno Pijl, A Edo Meinders, Ingrid M Jaze. A 5-day high-fat, high-calorie diet impairs insulin sensitivity in healthy, young South Asian men but not in Caucasian men. Diabetes. vol 63. issue 1. 2014-02-24. PMID:24357702. |
we conclude that hfhc feeding rapidly induces insulin resistance only in sas. |
2014-02-24 |
2023-08-12 |
Not clear |