| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Geraldine Harriman, Jeremy Greenwood, Sathesh Bhat, Xinyi Huang, Ruiying Wang, Debamita Paul, Liang Tong, Asish K Saha, William F Westlin, Rosana Kapeller, H James Harwoo. Acetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in rats. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 13. 2016-09-01. PMID:26976583. |
when administered chronically to rats with diet-induced obesity, nd-630 reduces hepatic steatosis, improves insulin sensitivity, reduces weight gain without affecting food intake, and favorably affects dyslipidemia. |
2016-09-01 |
2023-08-13 |
rat |
| Nicole M Templeman, Arya E Mehran, James D Johnso. Hyper-Variability in Circulating Insulin, High Fat Feeding Outcomes, and Effects of Reducing Ins2 Dosage in Male Ins1-Null Mice in a Specific Pathogen-Free Facility. PloS one. vol 11. issue 4. 2016-09-01. PMID:27055260. |
hyper-variability in circulating insulin, high fat feeding outcomes, and effects of reducing ins2 dosage in male ins1-null mice in a specific pathogen-free facility. |
2016-09-01 |
2023-08-13 |
mouse |
| Igor Cigarroa, Jaume F Lalanza, Antoni Caimari, Josep M del Bas, Lluís Capdevila, Lluís Arola, Rosa M Escorihuel. Treadmill Intervention Attenuates the Cafeteria Diet-Induced Impairment of Stress-Coping Strategies in Young Adult Female Rats. PloS one. vol 11. issue 4. 2016-09-01. PMID:27099927. |
caf feeding increased the weight gain, relative retroperitoneal white adipose tissue (rwat %), and plasma levels of glucose, insulin, triglycerides and leptin and decreased the insulin sensitivity. |
2016-09-01 |
2023-08-13 |
human |
| A P S Dornellas, R L H Watanabe, G D Pimentel, V T Boldarine, C M O Nascimento, L M Oyama, K Ghebremeskel, Y Wang, A A Bueno, E B Ribeir. Deleterious effects of lard-enriched diet on tissues fatty acids composition and hypothalamic insulin actions. Prostaglandins, leukotrienes, and essential fatty acids. vol 102-103. 2016-08-30. PMID:26525379. |
these findings suggest that impairment of hypothalamic insulin actions by hs-lp feeding was not related to tissue fa composition. |
2016-08-30 |
2023-08-13 |
rat |
| Lei Liu, Shaohua Xu, Xiaojuan Wang, Hongchao Jiao, Hai Li. Peripheral Insulin Doesn't Alter Appetite of Broiler Chicks. Asian-Australasian journal of animal sciences. vol 29. issue 9. 2016-08-30. PMID:26954230. |
six-d-age chicks with ad libitum feeding or fasting for 3 h before injection received a subcutaneous injection of 0, 1, 3, 5, 10, or 20 iu of insulin or vehicle (saline). |
2016-08-30 |
2023-08-13 |
Not clear |
| Lei Liu, Shaohua Xu, Xiaojuan Wang, Hongchao Jiao, Hai Li. Peripheral Insulin Doesn't Alter Appetite of Broiler Chicks. Asian-Australasian journal of animal sciences. vol 29. issue 9. 2016-08-30. PMID:26954230. |
the results showed peripheral insulin treatment (1 to 20 iu) did not alter significantly the feed intake in chicks under either ad libitum feeding or fasting conditions within 4 h (p>0.05). |
2016-08-30 |
2023-08-13 |
Not clear |
| Lei Liu, Shaohua Xu, Xiaojuan Wang, Hongchao Jiao, Hai Li. Peripheral Insulin Doesn't Alter Appetite of Broiler Chicks. Asian-Australasian journal of animal sciences. vol 29. issue 9. 2016-08-30. PMID:26954230. |
compared with the control, plasma glucose concentration was significantly decreased after insulin treatment of 3, 5, 10, and 20 iu for 4 h in chicks with ad libitum feeding (p<0.05). |
2016-08-30 |
2023-08-13 |
Not clear |
| Amanda L Suchanek, Lisa M Salat. Construction and evaluation of an adenoviral vector for the liver-specific expression of the serine/arginine-rich splicing factor, SRSF3. Plasmid. vol 82. 2016-08-29. PMID:26241824. |
in liver, expression of srsf3 is relatively low and its activity is increased in response to insulin and feeding a high carbohydrate diet. |
2016-08-29 |
2023-08-13 |
rat |
| Sadeesh K Ramakrishnan, Saja S Khuder, Qusai Y Al-Share, Lucia Russo, Simon L Abdallah, Payal R Patel, Garrett Heinrich, Harrison T Muturi, Brahma R Mopidevi, Ana Maria Oyarce, Yatrik M Shah, Edwin R Sanchez, Sonia M Najja. PPARα (Peroxisome Proliferator-activated Receptor α) Activation Reduces Hepatic CEACAM1 Protein Expression to Regulate Fatty Acid Oxidation during Fasting-refeeding Transition. The Journal of biological chemistry. vol 291. issue 15. 2016-08-29. PMID:26846848. |
consequently, wy14,643 feeding reduces hepatic ceacam1 mrna and ceacam1 protein levels, thus decreasing insulin clearance to compensate for compromised insulin secretion and maintain glucose homeostasis and insulin sensitivity in wild-type mice. |
2016-08-29 |
2023-08-13 |
mouse |
| Roy G Smit. Dissociating ghrelin-dependent G protein from β-arrestin-2 signaling in transgenic rats. Science signaling. vol 9. issue 424. 2016-08-24. PMID:27095592. |
these mutant rats are more responsive to endogenous ghrelin, resulting in increased fat deposition and insulin resistance without affecting food intake. |
2016-08-24 |
2023-08-13 |
rat |
| Sophie M Steculorum, Johan Ruud, Ismene Karakasilioti, Heiko Backes, Linda Engström Ruud, Katharina Timper, Martin E Hess, Eva Tsaousidou, Jan Mauer, Merly C Vogt, Lars Paeger, Stephan Bremser, Andreas C Klein, Donald A Morgan, Peter Frommolt, Paul T Brinkkötter, Philipp Hammerschmidt, Thomas Benzing, Kamal Rahmouni, F Thomas Wunderlich, Peter Kloppenburg, Jens C Brünin. AgRP Neurons Control Systemic Insulin Sensitivity via Myostatin Expression in Brown Adipose Tissue. Cell. vol 165. issue 1. 2016-08-23. PMID:27015310. |
stimulation of agrp → lha projections impairs insulin sensitivity and promotes feeding while activation of agrp → anterior bed nucleus of the stria terminalis (abnst)vl projections, distinct from agrp → abnstdm projections controlling feeding, mediate the effect of agrp neuron activation on bat-myostatin expression and insulin sensitivity. |
2016-08-23 |
2023-08-13 |
mouse |
| Susumu Hirabayashi, Ross L Caga. Salt-inducible kinases mediate nutrient-sensing to link dietary sugar and tumorigenesis in Drosophila. eLife. vol 4. 2016-08-22. PMID:26573956. |
feeding drosophila a high dietary sugar was previously demonstrated to not only direct metabolic defects including obesity and organismal insulin resistance, but also transform ras/src-activated cells into aggressive tumors. |
2016-08-22 |
2023-08-13 |
drosophila_melanogaster |
| Samantha E Adamson, Rachael Griffiths, Radim Moravec, Subramanian Senthivinayagam, Garren Montgomery, Wenshu Chen, Jenny Han, Poonam R Sharma, Garrett R Mullins, Stacey A Gorski, Jonathan A Cooper, Alexandra Kadl, Kyle Enfield, Thomas J Braciale, Thurl E Harris, Norbert Leitinge. Disabled homolog 2 controls macrophage phenotypic polarization and adipose tissue inflammation. The Journal of clinical investigation. vol 126. issue 4. 2016-08-15. PMID:26927671. |
moreover, chronic high-fat feeding exacerbated adipose tissue inflammation, m1 polarization of adipose tissue macrophages, and the development of insulin resistance in dab2-deficient animals compared with controls. |
2016-08-15 |
2023-08-13 |
mouse |
| Daniel B William. Inhibitory effects of insulin on GABAA currents modulated by the GABAA alpha subunit. Journal of receptor and signal transduction research. vol 35. issue 6. 2016-08-11. PMID:25224408. |
the differences in insulin inhibition of gaba currents at different α containing gabaa receptors could be important in autocrine and paracrine control of hormone secretion in the pancreas, and in control of reward and food intake circuits of the brain. |
2016-08-11 |
2023-08-13 |
xenopus_laevis |
| Maximilian Michel, Patrick S Page-McCaw, Wenbiao Chen, Roger D Con. Leptin signaling regulates glucose homeostasis, but not adipostasis, in the zebrafish. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 11. 2016-08-11. PMID:26903647. |
furthermore, larval zebrafish have been shown to exhibit β-cell hyperplasia in response to high fat feeding or peripheral insulin resistance, and we show here that leptin receptor is required for this response. |
2016-08-11 |
2023-08-13 |
mouse |
| Gregory N Ruegsegger, Ryan G Toedebusch, Joshua F Braselton, Christian K Roberts, Frank W Boot. Reduced metabolic disease risk profile by voluntary wheel running accompanying juvenile Western diet in rats bred for high and low voluntary exercise. Physiology & behavior. vol 152. issue Pt A. 2016-08-08. PMID:26367453. |
wheel access led to differences in body weight, food intake, and serum leptin and insulin. |
2016-08-08 |
2023-08-13 |
rat |
| Almesh Kadakol, Anuradha Pandey, Santosh Kumar Goru, Vajir Malek, Anil Bhanudas Gaikwa. Insulin sensitizing and cardioprotective effects of Esculetin and Telmisartan combination by attenuating Ang II mediated vascular reactivity and cardiac fibrosis. European journal of pharmacology. vol 765. 2016-08-08. PMID:26409041. |
insulin resistance was developed by high fat diet (hfd) feeding to wistar rats. |
2016-08-08 |
2023-08-13 |
rat |
| Sarthak Matravadia, Piotr Zabielski, Adrian Chabowski, David M Mutch, Graham P Hollowa. LA and ALA prevent glucose intolerance in obese male rats without reducing reactive lipid content, but cause tissue-specific changes in fatty acid composition. American journal of physiology. Regulatory, integrative and comparative physiology. vol 310. issue 7. 2016-08-08. PMID:26764053. |
after the 12-wk feeding intervention, both la- and ala-supplemented diets prevented whole body glucose and insulin intolerance; however, ala had a more pronounced effect. |
2016-08-08 |
2023-08-13 |
rat |
| Tomoyuki Kurashina, Katsuya Dezaki, Masashi Yoshida, Rauza Sukma Rita, Kiyonori Ito, Masanobu Taguchi, Rina Miura, Makoto Tominaga, Shun Ishibashi, Masafumi Kakei, Toshihiko Yad. The β-cell GHSR and downstream cAMP/TRPM2 signaling account for insulinostatic and glycemic effects of ghrelin. Scientific reports. vol 5. 2016-08-04. PMID:26370322. |
gastric hormone ghrelin regulates insulin secretion, as well as growth hormone release, feeding behavior and adiposity. |
2016-08-04 |
2023-08-13 |
mouse |
| Shuai Liu, Andrea K Globa, Fergil Mills, Lindsay Naef, Min Qiao, Shernaz X Bamji, Stephanie L Borglan. Consumption of palatable food primes food approach behavior by rapidly increasing synaptic density in the VTA. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 9. 2016-08-01. PMID:26884159. |
administration of insulin into the vta, which suppresses excitatory synaptic transmission onto dopamine neurons, can abolish food approach behaviors and food intake observed days after 24-h access to shf. |
2016-08-01 |
2023-08-13 |
Not clear |