| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| An Liu, Chenggang Huang, Jia Xu, Xuehong Ca. Lentivirus-mediated shRNA interference of ghrelin receptor blocks proliferation in the colorectal cancer cells. Cancer medicine. vol 5. issue 9. 2017-11-16. PMID:27464938. |
moreover, it has a range of biological actions, including the stimulation of food intake, modulation of insulin signaling and cardiovascular effects. |
2017-11-16 |
2023-08-13 |
mouse |
| T Ntallaris, P Humblot, R Båge, Y Sjunnesson, J Dupont, B Berglun. Effect of energy balance profiles on metabolic and reproductive response in Holstein and Swedish Red cows. Theriogenology. vol 90. 2017-11-13. PMID:28166980. |
this study examined the effect of two feeding levels during the antepartum and postpartum period on reproductive performance and blood metabolites (glucose, non-esterified fatty acids (nefa), insulin) in primiparous holstein and swedish red (srb) cows, in order to identify possible differences in the way these breeds respond to negative energy balance after calving. |
2017-11-13 |
2023-08-13 |
Not clear |
| Magdalene K Montgomery, Simon H J Brown, Xin Y Lim, Corrine E Fiveash, Brenna Osborne, Nicholas L Bentley, Jeremy P Braude, Todd W Mitchell, Adelle C F Coster, Anthony S Don, Gregory J Cooney, Carsten Schmitz-Peiffer, Nigel Turne. Regulation of glucose homeostasis and insulin action by ceramide acyl-chain length: A beneficial role for very long-chain sphingolipid species. Biochimica et biophysica acta. vol 1861. issue 11. 2017-11-03. PMID:27591968. |
in a recent study, we showed that in response to high fat feeding c57bl/6, 129x1, dba/2 and fvb/n mice all developed glucose intolerance, while balb/c mice displayed minimal deterioration in glucose tolerance and insulin action. |
2017-11-03 |
2023-08-13 |
mouse |
| Nikolaos Koukias, Elena Buzzetti, Emmanuel A Tsochatzi. Intestinal hormones, gut microbiota and non-alcoholic fatty liver disease. Minerva endocrinologica. vol 42. issue 2. 2017-11-02. PMID:27879962. |
intestinal hormones regulate multiple biological functions and may play a role in the pathogenesis of non alcoholic fatty liver disease (nafld) by affecting food intake, body weight and insulin resistance. |
2017-11-02 |
2023-08-13 |
Not clear |
| M Hansen, M J Scheltema, D P Sonne, J S Hansen, M Sperling, J F Rehfeld, J J Holst, T Vilsbøll, F K Kno. Effect of chenodeoxycholic acid and the bile acid sequestrant colesevelam on glucagon-like peptide-1 secretion. Diabetes, obesity & metabolism. vol 18. issue 6. 2017-10-31. PMID:26888164. |
to evaluate the effects of the primary human bile acid, chenodeoxycholic acid (cdca), and the bile acid sequestrant (bas) colesevelam, instilled into the stomach, on plasma levels of glucagon-like peptide-1 (glp-1), glucose-dependent insulinotropic polypeptide, glucose, insulin, c-peptide, glucagon, cholecystokinin and gastrin, as well as on gastric emptying, gallbladder volume, appetite and food intake. |
2017-10-31 |
2023-08-13 |
human |
| Ting Wang, Xiaohuan Zhu, Fang Dai, Chaofei Li, Dake Huang, Zhaohui Fang, Qiu Zhang, Yunxia L. Effects of a standard high-fat diet with or without multiple deficiencies on bone parameters in ovariectomized mature rat. PloS one. vol 12. issue 9. 2017-10-31. PMID:28950016. |
seven months of hfd and hfdd feeding resulted in obesity and insulin resistance in female sd rats. |
2017-10-31 |
2023-08-13 |
rat |
| Amanda P Siegel, Ali Daneshkhah, Dana S Hardin, Sudhir Shrestha, Kody Varahramyan, Mangilal Agarwa. Analyzing breath samples of hypoglycemic events in type 1 diabetes patients: towards developing an alternative to diabetes alert dogs. Journal of breath research. vol 11. issue 2. 2017-10-30. PMID:28569238. |
patients with type 1 diabetes (t1d) require insulin injections and measured food intake to maintain clinical stability, manually tracking their results by measuring blood glucose levels. |
2017-10-30 |
2023-08-13 |
Not clear |
| Su-Min Lim, Soo-Hyun Park, Naveen Sharma, Sung-Su Kim, Jae-Ryeong Lee, Jun-Sub Jung, Hong-Won Su. Blood glucose regulation mechanism in depressive disorder animal model during hyperglycemic states. Brain research bulletin. vol 124. 2017-10-26. PMID:27034116. |
the up-regulated insulin level induced by d-glucose feeding or restraint stress was reduced in the depression group. |
2017-10-26 |
2023-08-13 |
mouse |
| Amanda Brondani Mucellini, Natasha Kim de Oliveira da Fonseca, Gisele Gus Manfro, Patrícia Pelufo Silveir. Hippocampal insulin resistance and altered food decision-making as players on obesity risk. Neuroscience and biobehavioral reviews. vol 77. 2017-10-26. PMID:28342765. |
insulin also has been linked to brain functions such as feeding behavior and the imbalance of its mechanism of action on hippocampus is being related to cognitive dysfunction. |
2017-10-26 |
2023-08-13 |
Not clear |
| Joseph Lim, Christiani Jeyakumar Henry, Sumanto Halda. Vinegar as a functional ingredient to improve postprandial glycemic control-human intervention findings and molecular mechanisms. Molecular nutrition & food research. vol 60. issue 8. 2017-10-23. PMID:27213723. |
these mechanisms include (i) activation of the free fatty acid receptor 2 (ffar2) receptors localized in the enteroendocrine l-cells of the intestinal lumen, leading to increased glucagon like peptide 1 (glp-1) secretion, (ii) increased 5'adenosine monophosphate-activated protein kinase (ampk) activation, leading to increased fatty acid oxidation and decreased hepatic gluconeogenesis, (iii) lowering of free fatty acid in circulation, potentially leading to improved insulin sensitivity, (iv) increased blood flow to the peripheral tissues and (v) increased satiety, leading to lower food intake. |
2017-10-23 |
2023-08-13 |
human |
| Xin Rong, Bo Wang, Elisa Nd Palladino, Thomas Q de Aguiar Vallim, David A Ford, Peter Tontono. ER phospholipid composition modulates lipogenesis during feeding and in obesity. The Journal of clinical investigation. vol 127. issue 10. 2017-10-19. PMID:28846071. |
conversely, lpcat3 deficiency increased membrane saturation, reduced nuclear srebp-1c abundance, and blunted the lipogenic response to feeding, lxr agonist treatment, or obesity-linked insulin resistance. |
2017-10-19 |
2023-08-13 |
Not clear |
| Gang Xu, Juan Ye, Xue-Jing Liu, Ning-Ping Zhang, Yi-Ming Zhao, Jia Fan, Xiu-Ping Liu, Jian W. Activation of pluripotent genes in hepatic progenitor cells in the transition of nonalcoholic steatohepatitis to pre-malignant lesions. Laboratory investigation; a journal of technical methods and pathology. vol 97. issue 10. 2017-10-11. PMID:28869588. |
after feeding high-fat/calorie diet plus high fructose/glucose in drinking water (hfc diet plus hf/g) for up to 12 months, mice developed obesity, insulin resistance, and steatohepatitis with significant necroptotic inflammation and fibrotic progression, as well as occurrence of hyperplastic nodules with dysplasia; and this model represents pathohistologically as a transition from nash to nash-hcc in a pre-carcinomatous stage. |
2017-10-11 |
2023-08-13 |
mouse |
| Christine Loyd, Yanping Liu, Teayoun Kim, Cassie Holleman, Jamie Galloway, Maigen Bethea, Benjamin N Ediger, Thomas A Swain, Yawen Tang, Doris A Stoffers, Glenn C Rowe, Martin Young, Chad Steele, Kirk M Habegger, Chad S Hunte. LDB1 Regulates Energy Homeostasis During Diet-Induced Obesity. Endocrinology. vol 158. issue 5. 2017-10-10. PMID:28009534. |
we assessed glucose and insulin tolerance, body composition, feeding, and energy expenditure during high-fat diet exposure. |
2017-10-10 |
2023-08-13 |
mouse |
| Kazuki Tajima, Jun Shirakawa, Tomoko Okuyama, Mayu Kyohara, Shunsuke Yamazaki, Yu Togashi, Yasuo Terauch. Effects of metformin on compensatory pancreatic β-cell hyperplasia in mice fed a high-fat diet. American journal of physiology. Endocrinology and metabolism. vol 313. issue 3. 2017-10-10. PMID:28512156. |
interestingly, metformin suppressed β-cell proliferation induced by 1 wk of hfd feeding without any changes in insulin resistance. |
2017-10-10 |
2023-08-13 |
mouse |
| Jian-Li Wang, Xian-Hui Xu, Xue-Jun Zhang, Wei-Hua L. The role of obestatin in roux-en-Y gastric bypass-induced remission of type 2 diabetes mellitus. Diabetes/metabolism research and reviews. vol 32. issue 6. 2017-10-06. PMID:26445403. |
obestatin is a 23-amino-acid peptide, which is not only thought to suppress food intake and decrease gastric emptying but also found to exert survival effects in pancreatic β cells, increase glucose-stimulated insulin secretion, and reduce insulin resistance and inflammation. |
2017-10-06 |
2023-08-13 |
Not clear |
| Kazuhiko Nishida, Kinya Ots. Inflammation and metabolic cardiomyopathy. Cardiovascular research. vol 113. issue 4. 2017-10-02. PMID:28395010. |
excessive feeding is associated with an increase in the incidence of chronic metabolic diseases, such as obesity, insulin resistance, and type 2 diabetes. |
2017-10-02 |
2023-08-13 |
Not clear |
| Lene Jessen, Eric P Smith, Yvonne Ulrich-Lai, James P Herman, Randy J Seeley, Darleen Sandoval, David D'Alessi. Central Nervous System GLP-1 Receptors Regulate Islet Hormone Secretion and Glucose Homeostasis in Male Rats. Endocrinology. vol 158. issue 7. 2017-09-29. PMID:28430981. |
paradoxically, glp-1r blockade with icv ex-9 also reduced glucose-stimulated insulin secretion, and administration of icv ex-9 to freely feeding rats caused mild glucose intolerance. |
2017-09-29 |
2023-08-13 |
rat |
| Yan Guo, Chao-Qian Liu, Cheng-Xiang Shan, Yue Chen, Hui-Hua Li, Zhi-Ping Huang, Da-Jin Zo. Gut microbiota after Roux-en-Y gastric bypass and sleeve gastrectomy in a diabetic rat model: Increased diversity and associations of discriminant genera with metabolic changes. Diabetes/metabolism research and reviews. vol 33. issue 3. 2017-09-26. PMID:27572277. |
most of the 12 discriminant genera correlated with changes in metabolic phenotype, but only 28.6% of these correlations were independent of weight, and 4 discriminant genera still negatively correlated with serum insulin level independent of food intake and weight loss after rygb. |
2017-09-26 |
2023-08-13 |
rat |
| Dhananjay Gupta, Thomas L Jetton, Kyla LaRock, Navjot Monga, Basanthi Satish, James Lausier, Mina Peshavaria, Jack L Leah. Temporal characterization of β cell-adaptive and -maladaptive mechanisms during chronic high-fat feeding in C57BL/6NTac mice. The Journal of biological chemistry. vol 292. issue 30. 2017-09-26. PMID:28487366. |
insulin sensitivity was not significantly perturbed until 11 weeks of hfd feeding. |
2017-09-26 |
2023-08-13 |
mouse |
| Beatriz C Borges, Carol F Elias, Lucila L K Elia. PI3K signaling: A molecular pathway associated with acute hypophagic response during inflammatory challenges. Molecular and cellular endocrinology. vol 438. 2017-09-25. PMID:27389879. |
this study presents an overview of the current knowledge about pi3k role on cytokines and insulin signaling in the hypothalamic regulation of feeding during inflammation. |
2017-09-25 |
2023-08-13 |
Not clear |