| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Vettor, N Zarjevski, I Cusin, F Rohner-Jeanrenaud, B Jeanrenau. Induction and reversibility of an obesity syndrome by intracerebroventricular neuropeptide Y administration to normal rats. Diabetologia. vol 37. issue 12. 1995-04-25. PMID:7895949. |
intracerebroventricular neuropeptide y (npy) administration to normal rats for 7 days produced a sustained, threefold increase in food intake, resulting in a body weight gain of more than 40 g. basal plasma insulin and triglyceride levels were increased in npy-treated compared to vehicle-infused rats by about four- and two-fold, respectively. |
1995-04-25 |
2023-08-12 |
rat |
| E Santti, R Huupponen, J Rouru, V Hänninen, U Pesonen, M Jhanwar-Uniyal, M Koul. Potentiation of the anti-obesity effect of the selective beta 3-adrenoceptor agonist BRL 35135 in obese Zucker rats by exercise. British journal of pharmacology. vol 113. issue 4. 1995-04-19. PMID:7889277. |
body weight gain, cumulative food intake, the neuropeptide y content of the hypothalamic paraventricular nucleus, brown adipose tissue thermogenic activity (measured as gdp binding), plasma insulin and glucose levels were measured after 3 weeks' treatment and exercise. |
1995-04-19 |
2023-08-12 |
rat |
| E Santti, R Huupponen, J Rouru, V Hänninen, U Pesonen, M Jhanwar-Uniyal, M Koul. Potentiation of the anti-obesity effect of the selective beta 3-adrenoceptor agonist BRL 35135 in obese Zucker rats by exercise. British journal of pharmacology. vol 113. issue 4. 1995-04-19. PMID:7889277. |
exercise alone had no effect on weight gain, food intake or thermogenic activity, whereas it reduced plasma insulin and glucose levels. |
1995-04-19 |
2023-08-12 |
rat |
| A M Mistry, N G Chen, Y S Lee, D R Romso. Consumption of a glucose diet enhances the sensitivity of pancreatic islets from adrenalectomized genetically obese (ob/ob) mice to glucose-induced insulin secretion. The Journal of nutrition. vol 125. issue 3. 1995-04-06. PMID:7876925. |
the present study examined regulation of insulin secretion from perifused pancreatic islets of female adrenalectomized genetically obese (ob/ob) and lean mice fed a glucose diet for 4 d. these mice were fed a high carbohydrate commercial diet for 21 d, or the high carbohydrate commercial diet for 17 d and a purified high glucose diet for the last 4 d of the 21-d feeding period. |
1995-04-06 |
2023-08-12 |
mouse |
| H L Chen, D R Romso. A single intracerebroventricular injection of dexamethasone elevates food intake and plasma insulin and depresses metabolic rates in adrenalectomized obese (ob/ob) mice. The Journal of nutrition. vol 125. issue 3. 1995-04-06. PMID:7876929. |
a single intracerebroventricular injection of dexamethasone elevates food intake and plasma insulin and depresses metabolic rates in adrenalectomized obese (ob/ob) mice. |
1995-04-06 |
2023-08-12 |
mouse |
| H L Chen, D R Romso. A single intracerebroventricular injection of dexamethasone elevates food intake and plasma insulin and depresses metabolic rates in adrenalectomized obese (ob/ob) mice. The Journal of nutrition. vol 125. issue 3. 1995-04-06. PMID:7876929. |
a single icv injection of dexamethasone increased food intake 32% and plasma insulin 81%, and depressed oxygen consumption 11%, in adrenalectomized ob/ob mice during the 24-h period after injection, without increasing food intake or plasma insulin in lean mice. |
1995-04-06 |
2023-08-12 |
mouse |
| T J Bartness, J E Morley, A S Levin. Effects of food deprivation and metabolic fuel utilization on the photoperiodic control of food intake in Siberian hamsters. Physiology & behavior. vol 57. issue 1. 1995-04-05. PMID:7710560. |
; (b) is food intake increased following treatments that block metabolic fuel utilization, such as the glucose utilization blocker 2-deoxy-d-glucose (2 dg), or that enhance storage of metabolic fuels, such as short acting insulin (regular insulin)? |
1995-04-05 |
2023-08-12 |
rat |
| T J Bartness, J E Morley, A S Levin. Effects of food deprivation and metabolic fuel utilization on the photoperiodic control of food intake in Siberian hamsters. Physiology & behavior. vol 57. issue 1. 1995-04-05. PMID:7710560. |
food intake was measured in response to fasting, insulin or 2 dg treatment in adult female siberian hamsters housed in long photoperiods. |
1995-04-05 |
2023-08-12 |
rat |
| T J Bartness, J E Morley, A S Levin. Effects of food deprivation and metabolic fuel utilization on the photoperiodic control of food intake in Siberian hamsters. Physiology & behavior. vol 57. issue 1. 1995-04-05. PMID:7710560. |
similarly, food intake was increased by treatment with regular insulin in long days, but not short days. |
1995-04-05 |
2023-08-12 |
rat |
| P F Aravich, E Z Stanley, L E Doerrie. Exercise in food-restricted rats produces 2DG feeding and metabolic abnormalities similar to anorexia nervosa. Physiology & behavior. vol 57. issue 1. 1995-04-05. PMID:7878108. |
this investigation determined if the weight-loss phenomenon is associated with a paradoxical suppression of food intake following 2dg and if the effect is related to reductions in prevailing glucose and insulin levels. |
1995-04-05 |
2023-08-12 |
rat |
| L Gnudi, E Tozzo, P R Shepherd, J L Bliss, B B Kah. High level overexpression of glucose transporter-4 driven by an adipose-specific promoter is maintained in transgenic mice on a high fat diet, but does not prevent impaired glucose tolerance. Endocrinology. vol 136. issue 3. 1995-03-29. PMID:7867610. |
high fat feeding is associated with impaired insulin action, an obese body composition, and down-regulation of glucose transporter-4 (glut4) expression in adipocytes. |
1995-03-29 |
2023-08-12 |
mouse |
| A J Sipols, D G Baskin, M W Schwart. Effect of intracerebroventricular insulin infusion on diabetic hyperphagia and hypothalamic neuropeptide gene expression. Diabetes. vol 44. issue 2. 1995-03-21. PMID:7859932. |
food and water intake were significantly increased in diabetic rats, but only food intake was affected by icv insulin. |
1995-03-21 |
2023-08-12 |
rat |
| A J Sipols, D G Baskin, M W Schwart. Effect of intracerebroventricular insulin infusion on diabetic hyperphagia and hypothalamic neuropeptide gene expression. Diabetes. vol 44. issue 2. 1995-03-21. PMID:7859932. |
to evaluate whether central nervous system (cns) insulin deficiency affects expression of neuropeptides involved in food intake, in situ hybridization was done for neuropeptide y (npy), which stimulates feeding, in the hypothalamic arcuate nucleus and for cholecystokinin (cck) and corticotropin-releasing hormone (crh), which inhibit feeding, in the hypothalamic paraventricular nucleus. |
1995-03-21 |
2023-08-12 |
rat |
| J Luo, S W Rizkalla, M Lerer-Metzger, J Boillot, A Ardeleanu, F Bruzzo, A Chevalier, G Slam. A fructose-rich diet decreases insulin-stimulated glucose incorporation into lipids but not glucose transport in adipocytes of normal and diabetic rats. The Journal of nutrition. vol 125. issue 2. 1995-03-21. PMID:7861242. |
to study the cellular mechanisms underlying fructose-induced insulin resistance in rats, the effects of fructose feeding on insulin-stimulated glucose transport, oxidation and incorporation into lipids in epididymal adipocytes were evaluated in 27 normal and 27 noninsulin-dependent diabetic male sprague-dawley rats. |
1995-03-21 |
2023-08-12 |
rat |
| P R Ling, N W Istfan, E Colon, B R Bistria. Differential effects of interleukin-1 receptor antagonist in cytokine- and endotoxin-treated rats. The American journal of physiology. vol 268. issue 2 Pt 1. 1995-03-21. PMID:7864101. |
the results showed that during feeding il-1 is responsible for the increase in glucose flux and plasma insulin, the development of insulin resistance, and plasma zinc depression during condition mimicking sepsis and injury, similar to effects observed in the fasting state. |
1995-03-21 |
2023-08-12 |
rat |
| A D Kalopissis, G Griffaton, D Fa. Inhibition of hepatic very-low-density lipoprotein secretion in obese Zucker rats adapted to a high-protein diet. Metabolism: clinical and experimental. vol 44. issue 1. 1995-03-14. PMID:7854160. |
plasma glucagon increased in both phenotypes under hp feeding, whereas plasma insulin either increased (obese) or decreased (lean), with the insulin to glucagon ratio slightly decreasing. |
1995-03-14 |
2023-08-12 |
rat |
| I Bergerot, N Fabien, V Maguer, C Thivole. Oral administration of human insulin to NOD mice generates CD4+ T cells that suppress adoptive transfer of diabetes. Journal of autoimmunity. vol 7. issue 5. 1995-03-06. PMID:7840857. |
in the present study, we demonstrate that feeding 6-week-old female mice with 20 units of human insulin every 2-3 days for 30 days induces an active mechanism of suppression through the generation of regulatory t cells. |
1995-03-06 |
2023-08-12 |
mouse |
| S Bisbis, M Derouet, J Simo. Characterization of insulin receptors in chicken kidneys: effect of nutritional status. General and comparative endocrinology. vol 96. issue 1. 1995-03-03. PMID:7843566. |
insulin binding was significantly higher (p < 0.05) following 48 hr fasting and lower (p < 0.05) following refeeding compared to ad libitum feeding. |
1995-03-03 |
2023-08-12 |
chicken |
| A M Strack, R J Sebastian, M W Schwartz, M F Dallma. Glucocorticoids and insulin: reciprocal signals for energy balance. The American journal of physiology. vol 268. issue 1 Pt 2. 1995-02-27. PMID:7840315. |
increasingly strong evidence indicates that insulin, acting on the central nervous system in part through its effect on neuropeptide y (npy), inhibits food intake. |
1995-02-27 |
2023-08-12 |
rat |
| A M Strack, R J Sebastian, M W Schwartz, M F Dallma. Glucocorticoids and insulin: reciprocal signals for energy balance. The American journal of physiology. vol 268. issue 1 Pt 2. 1995-02-27. PMID:7840315. |
glucocorticoids stimulated and insulin inhibited npy mrna and food intake. |
1995-02-27 |
2023-08-12 |
rat |