| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stephen C Benoit, John-Andrews McQuade, Deborah J Clegg, Ming Xu, Paul A Rushing, Stephen C Woods, Randy J Seele. Altered feeding responses in mice with targeted disruption of the dopamine-3 receptor gene. Behavioral neuroscience. vol 117. issue 1. 2003-05-20. PMID:12619907. |
in the present experiments, the authors assessed the role of the dopamine-3 receptor (d3r) in the feeding responses to 2-deoxy-d-glucose, mercaptoacetate, and peripheral insulin. |
2003-05-20 |
2023-08-12 |
mouse |
| Kyriaki Gerozissis, Gerozissis Kyriak. Brain insulin: regulation, mechanisms of action and functions. Cellular and molecular neurobiology. vol 23. issue 1. 2003-05-20. PMID:12701881. |
a specific role on cognitive functions related to feeding is proposed, and it is suggested that brain insulin from different sources might be involved in the above vital functions in health and disease. |
2003-05-20 |
2023-08-12 |
Not clear |
| Kyriaki Gerozissis, Gerozissis Kyriak. Brain insulin: regulation, mechanisms of action and functions. Cellular and molecular neurobiology. vol 23. issue 1. 2003-05-20. PMID:12701881. |
a molecule identical to pancreatic insulin, and specific insulin receptors, are found widely distributed in the central nervous system networks related to feeding, reproduction, or cognition. |
2003-05-20 |
2023-08-12 |
Not clear |
| Deborah J Clegg, Christine A Riedy, Kathleen A Blake Smith, Stephen C Benoit, Stephen C Wood. Differential sensitivity to central leptin and insulin in male and female rats. Diabetes. vol 52. issue 3. 2003-05-09. PMID:12606509. |
when the same rats were administered insulin (1 or 4 mu/2 microl) or saline (2 microl), male but not female rats had a robust reduction in food intake over 24 h. previous research demonstrates the melanocortins are a central mediator of the effects of both leptin and insulin. |
2003-05-09 |
2023-08-12 |
rat |
| T CAHN, J HOUGE. [Combined effect of insulin and of adrenalin on caloric output and on food intake in rabbits]. Comptes rendus hebdomadaires des seances de l'Academie des sciences. vol 239. issue 3. 2003-05-01. PMID:13199997. |
[combined effect of insulin and of adrenalin on caloric output and on food intake in rabbits]. |
2003-05-01 |
2023-08-12 |
Not clear |
| A SOULAIRAC, M L SOULAIRA. [Effect of insulin and chlorpromazine on feeding behavior of rats]. Journal de physiologie. vol 48. issue 3. 2003-05-01. PMID:13346611. |
[effect of insulin and chlorpromazine on feeding behavior of rats]. |
2003-05-01 |
2023-08-12 |
rat |
| Stephen C Woods, Randy J Seeley, Paul A Rushing, David D'Alessio, Patrick Ts. A controlled high-fat diet induces an obese syndrome in rats. The Journal of nutrition. vol 133. issue 4. 2003-04-30. PMID:12672923. |
when compared over 10 wk of free feeding, hf rats weighed 10% more (p < 0.01) than lf rats and had 50% more body fat (p < 0.01), as well as significant hyperleptinemia and insulin resistance. |
2003-04-30 |
2023-08-12 |
rat |
| Dawn E W Livingstone, Brian R Walke. Is 11beta-hydroxysteroid dehydrogenase type 1 a therapeutic target? Effects of carbenoxolone in lean and obese Zucker rats. The Journal of pharmacology and experimental therapeutics. vol 305. issue 1. 2003-04-22. PMID:12649365. |
carbenoxolone had no effect on weight gain or food intake, did not affect plasma glucose during an oral glucose tolerance test, and increased the plasma insulin response to glucose. |
2003-04-22 |
2023-08-12 |
human |
| Gwenn Coatmellec-Taglioni, Jean-Pierre Dausse, Yves Giudicelli, Catherine Ribièr. Sexual dimorphism in cafeteria diet-induced hypertension is associated with gender-related difference in renal leptin receptor down-regulation. The Journal of pharmacology and experimental therapeutics. vol 305. issue 1. 2003-04-22. PMID:12649390. |
feeding male, female, and testosterone-treated female rats a cafeteria diet for 10 weeks increased body fat mass, plasma insulin, and leptin levels. |
2003-04-22 |
2023-08-12 |
rat |
| Matthew Barber, Badrinarayanan S Kasturi, Maureen E Austin, Kaushik P Patel, Sheba M J MohanKumar, P S MohanKuma. Diabetes-induced neuroendocrine changes in rats: role of brain monoamines, insulin and leptin. Brain research. vol 964. issue 1. 2003-04-18. PMID:12573521. |
diabetes produced a marked increase in food intake and water intake and this effect was completely reversed by insulin treatment and partially reversed by leptin treatment (p<0.05). |
2003-04-18 |
2023-08-12 |
rat |
| Jay J Kuo, O Barrett Jones, John E Hal. Chronic cardiovascular and renal actions of leptin during hyperinsulinemia. American journal of physiology. Regulatory, integrative and comparative physiology. vol 284. issue 4. 2003-04-17. PMID:12521924. |
insulin plus glucose infusion reduced food intake to 55 +/- 7% of control, while leptin + insulin lowered food intake further to 22 +/- 4% of the initial control. |
2003-04-17 |
2023-08-12 |
human |
| Dianne P Figlewic. Adiposity signals and food reward: expanding the CNS roles of insulin and leptin. American journal of physiology. Regulatory, integrative and comparative physiology. vol 284. issue 4. 2003-04-17. PMID:12626355. |
the hormones insulin and leptin have been proposed to act in the central nervous system (cns) as adiposity signals as part of a theoretical negative feedback loop that senses the caloric stores of an animal and orchestrates adjustments in energy balance and food intake. |
2003-04-17 |
2023-08-12 |
Not clear |
| Kevin D Niswender, Christopher D Morrison, Deborah J Clegg, Ryan Olson, Denis G Baskin, Martin G Myers, Randy J Seeley, Michael W Schwart. Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia. Diabetes. vol 52. issue 2. 2003-04-07. PMID:12540590. |
finally, we show that the food intake- lowering effects of insulin are reversed by intracerebroventricular infusion of either of two pi3k inhibitors at doses that have no independent feeding effects. |
2003-04-07 |
2023-08-12 |
Not clear |
| Michael W Schwartz, Stephen C Woods, Randy J Seeley, Gregory S Barsh, Denis G Baskin, Rudolph L Leibe. Is the energy homeostasis system inherently biased toward weight gain? Diabetes. vol 52. issue 2. 2003-04-07. PMID:12540591. |
catabolic neuronal pathways are those that both reduce food intake and increase energy expenditure (e.g., melanocortin neurons in the hypothalamic arcuate nucleus) and are stimulated by input from insulin and leptin. |
2003-04-07 |
2023-08-12 |
Not clear |
| Michael W Schwartz, Stephen C Woods, Randy J Seeley, Gregory S Barsh, Denis G Baskin, Rudolph L Leibe. Is the energy homeostasis system inherently biased toward weight gain? Diabetes. vol 52. issue 2. 2003-04-07. PMID:12540591. |
in contrast, anabolic pathways (e.g., neurons containing neuropeptide y) are those that stimulate food intake and decrease energy expenditure and are strongly inhibited by these same basal concentrations of insulin and leptin. |
2003-04-07 |
2023-08-12 |
Not clear |
| Juei-Tang Cheng, I-Min Liu, Chih Fen Hs. Rapid induction of insulin resistance in opioid mu-receptor knock-out mice. Neuroscience letters. vol 339. issue 2. 2003-04-04. PMID:12614914. |
the wild-type mice or opioid mu-receptor knockout mice were employed to induce insulin resistance by feeding with fructose-rich chow or by the repeated intraperitoneal injections of long-acting form of human insulin at 0.5 iu/kg three times daily. |
2003-04-04 |
2023-08-12 |
mouse |
| P A Velasquez-Mieyer, P A Cowan, K L Arheart, C K Buffington, K A Spencer, B E Connelly, G W Cowan, R H Lusti. Suppression of insulin secretion is associated with weight loss and altered macronutrient intake and preference in a subset of obese adults. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. vol 27. issue 2. 2003-04-03. PMID:12587002. |
we investigated whether suppression of insulin secretion, without dietary or exercise intervention, could promote weight loss and alter food intake and preference in obese adults. |
2003-04-03 |
2023-08-12 |
Not clear |
| Darcy Putz, Udaya M Kabad. Insulin glargine in continuous enteric tube feeding. Diabetes care. vol 25. issue 10. 2003-03-31. PMID:12351503. |
insulin glargine in continuous enteric tube feeding. |
2003-03-31 |
2023-08-12 |
Not clear |
| P D Raposinho, D D Pierroz, P Broqua, R B White, T Pedrazzini, M L Auber. Chronic administration of neuropeptide Y into the lateral ventricle of C57BL/6J male mice produces an obesity syndrome including hyperphagia, hyperleptinemia, insulin resistance, and hypogonadism. Molecular and cellular endocrinology. vol 185. issue 1-2. 2003-03-28. PMID:11738809. |
the present study in the mouse suggests in analogy with available rat data, that constant exposure to elevated npy in the hypothalamic area unabatedly enhances food intake leading to an obesity syndrome including increased adiposity, insulin resistance, hypercorticism, and hypogonadism, reminiscent of the phenotype of the ob/ob mouse, that displays elevated hypothalamic npy secondary to lack of leptin negative feedback action. |
2003-03-28 |
2023-08-12 |
mouse |
| A Bhalla, K Tilling, P Kolominsky-Rabas, P Heuschmann, S E Megherbi, A Czlonkowska, A Kobayashi, T Mendel, M Giroud, A Rudd, C Wolf. Variation in the management of acute physiological parameters after ischaemic stroke: a European perspective. European journal of neurology. vol 10. issue 1. 2003-03-27. PMID:12534989. |
after adjusting for case mix, there were significant differences in intravenous fluid use (p = 0.04), enteral feeding (p = 0.003), initiation of new antihypertensive therapy (p = 0.0006) and insulin therapy (p = 0.004) between centres, with the london centre having the lowest uptake of interventions. |
2003-03-27 |
2023-08-12 |
Not clear |