| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nigel Irwin, Paula L McClean, Peter R Flat. Comparison of the subchronic antidiabetic effects of DPP IV-resistant GIP and GLP-1 analogues in obese diabetic (ob/ob) mice. Journal of peptide science : an official publication of the European Peptide Society. vol 13. issue 6. 2007-07-10. PMID:17486662. |
subchronic administration of n-acgip, (val8)glp-1 or combined peptide administration had no significant effects on the body weight, food intake and plasma insulin concentrations. |
2007-07-10 |
2023-08-12 |
mouse |
| Andrea L Hevener, Jerrold M Olefsky, Donna Reichart, M T Audrey Nguyen, Gautam Bandyopadyhay, Ho-Yin Leung, Matthew J Watt, Chris Benner, Mark A Febbraio, Anh-Khoi Nguyen, Brian Folian, Shankar Subramaniam, Frank J Gonzalez, Christopher K Glass, Mercedes Ricot. Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones. The Journal of clinical investigation. vol 117. issue 6. 2007-07-10. PMID:17525798. |
consistent with this, the relative degree of insulin resistance became more severe in mice lacking macrophage ppar gamma following high-fat feeding, and these mice were only partially responsive to tzd treatment. |
2007-07-10 |
2023-08-12 |
mouse |
| W-K Lee, S-T Kao, I-M Liu, J-T Chen. Ginsenoside Rh2 is one of the active principles of Panax ginseng root to improve insulin sensitivity in fructose-rich chow-fed rats. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 39. issue 5. 2007-07-03. PMID:17533576. |
thus, the repeated treatment of ginsenoside rh2 delayed the development of insulin resistance in high fructose feeding rats. |
2007-07-03 |
2023-08-12 |
human |
| Vincenzo Di Francesco, Francesco Fantin, Francesca Omizzolo, Luigi Residori, Luisa Bissoli, Ottavio Bosello, Mauro Zambon. The anorexia of aging. Digestive diseases (Basel, Switzerland). vol 25. issue 2. 2007-07-02. PMID:17468548. |
negative feedback from impaired gastric motility, exaggerated long-term adiposity signals (leptin, insulin) and postprandial anorexigenic signals (cck, pyy) seem to prevail over the central feeding drive. |
2007-07-02 |
2023-08-12 |
human |
| Nigel Irwin, Paula L McClean, Patrick Harriott, Peter R Flat. Beneficial effects of sub-chronic activation of glucagon-like peptide-1 (GLP-1) receptors on deterioration of glucose homeostasis and insulin secretion in aging mice. Experimental gerontology. vol 42. issue 4. 2007-06-29. PMID:17184947. |
daily injection of (val(8))glp-1 (25 n mol/kg body weight) for 12 days had no significant effect on food intake, body weight, non-fasting plasma glucose and insulin concentrations. |
2007-06-29 |
2023-08-12 |
mouse |
| Jameason Cameron, Eric Douce. Getting to the bottom of feeding behaviour: who's on top? Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. vol 32. issue 2. 2007-06-29. PMID:17486158. |
and long-term (insulin and leptin) feeding signals may be actively suppressed by the nested nuclei and projections of cortical-limbic brain areas. |
2007-06-29 |
2023-08-12 |
human |
| Francis Kim, Matilda Pham, Ian Luttrell, Douglas D Bannerman, Joan Tupper, Joshua Thaler, Thomas R Hawn, Elaine W Raines, Michael W Schwart. Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity. Circulation research. vol 100. issue 11. 2007-06-19. PMID:17478729. |
in response to hf feeding, both genotypes displayed similar increases of body weight, body fat content, and serum insulin and free fatty acid (ffa) levels compared with mice on a lf diet. |
2007-06-19 |
2023-08-12 |
mouse |
| E Decuypere, V Bruggema. The endocrine interface of environmental and egg factors affecting chick quality. Poultry science. vol 86. issue 5. 2007-06-12. PMID:17435044. |
in its turn, time of first feeding is related to some crucial hormone levels and enzyme activities for growth that are strongly influenced by posthatch food intake such as insulin and p70s6 kinase activity, a key enzyme in the control of protein synthesis. |
2007-06-12 |
2023-08-12 |
chicken |
| A P Arikawe, A O Daramola, A O Odofin, L F O Obik. Alloxan-induced and insulin-resistant diabetes mellitus affect semen parameters and impair spermatogenesis in male rats. African journal of reproductive health. vol 10. issue 3. 2007-06-12. PMID:17518137. |
male sprague-dawley rats weighing 180 - 200g were made diabetic by intravenous injection of alloxan (40 mg/kg): and insulin resistant by chronic fructose feeding (25% fructose) for 12 weeks. |
2007-06-12 |
2023-08-12 |
rat |
| Nichola M Thompson, Amy M Norman, Shawn S Donkin, Ravi R Shankar, Mark H Vickers, Jennifer L Miles, Bernhard H Breie. Prenatal and postnatal pathways to obesity: different underlying mechanisms, different metabolic outcomes. Endocrinology. vol 148. issue 5. 2007-06-04. PMID:17272392. |
as expected, high-fat feeding caused diet-induced obesity (dio) and insulin resistance. |
2007-06-04 |
2023-08-12 |
rat |
| Nicola Pannacciulli, Duc Son N T Le, Arline D Salbe, Kewei Chen, Eric M Reiman, Pietro A Tataranni, Jonathan Krakof. Postprandial glucagon-like peptide-1 (GLP-1) response is positively associated with changes in neuronal activity of brain areas implicated in satiety and food intake regulation in humans. NeuroImage. vol 35. issue 2. 2007-06-04. PMID:17317222. |
the peak postprandial increases in plasma glp-1 concentrations were correlated with increases in rcbf in the left dorsolateral prefrontal cortex (including the left middle and inferior frontal gyri), previously implicated in pet studies of human satiation, and the hypothalamus, previously implicated in the regulation of food intake in animal and human studies, both before and after adjustment for sex, age, body fat, and changes in plasma glucose, insulin, and serum ffa concentrations. |
2007-06-04 |
2023-08-12 |
human |
| Irena Konstantinova, Ganka Nikolova, Mica Ohara-Imaizumi, Paolo Meda, Tomás Kucera, Konstantinos Zarbalis, Wolfgang Wurst, Shinya Nagamatsu, Eckhard Lammer. EphA-Ephrin-A-mediated beta cell communication regulates insulin secretion from pancreatic islets. Cell. vol 129. issue 2. 2007-06-04. PMID:17448994. |
within these islets, communication between beta cells inhibits basal insulin secretion and enhances glucose-stimulated insulin secretion, thus contributing to glucose homeostasis during fasting and feeding. |
2007-06-04 |
2023-08-12 |
Not clear |
| E Herrera, I López-Soldado, M Limones, E Amusquivar, M P Ramo. Lipid metabolism during the perinatal phase, and its implications on postnatal development. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition. vol 76. issue 4. 2007-06-01. PMID:17243085. |
results show that the decreased food intake caused by a omega-3 fatty acid-rich diet rather than the change in milk composition during suckling was responsible for the reduced pancreatic glucose responsiveness to insulin release at 16 weeks of age. |
2007-06-01 |
2023-08-12 |
rat |
| F Kaine. [Fetal programming: prevention of perinatal acquired predispositions of diseases in later life]. Zeitschrift fur Geburtshilfe und Neonatologie. vol 211. issue 1. 2007-05-30. PMID:17327986. |
elevated insulin concentrations during critical periods of perinatal life may induce a lasting 'malprogramming' of neuroendocrine systems regulating body weight, food intake, and metabolism. |
2007-05-30 |
2023-08-12 |
Not clear |
| Sunmin Park, Jin Sun Jang, Sang Mee Hon. Long-term consumption of caffeine improves glucose homeostasis by enhancing insulinotropic action through islet insulin/insulin-like growth factor 1 signaling in diabetic rats. Metabolism: clinical and experimental. vol 56. issue 5. 2007-05-24. PMID:17445533. |
after a 12-week administration of 0.01% caffeine solution, the rats exhibited reduced body weight, fats, and insulin resistance, without a change in food intake, regardless of an 11% sucrose solution supplementation. |
2007-05-24 |
2023-08-12 |
rat |
| John W Bullen, Susann Bluher, Theodoros Kelesidis, Christos S Mantzoro. Regulation of adiponectin and its receptors in response to development of diet-induced obesity in mice. American journal of physiology. Endocrinology and metabolism. vol 292. issue 4. 2007-05-21. PMID:17164441. |
thus advanced age and high-fat feeding, both of which are factors that predispose humans to obesity and insulin resistance, are associated with decreasing adiponectin and increasing adipor1 and/or adipor2 levels. |
2007-05-21 |
2023-08-12 |
mouse |
| Dene Simpson, Paul L McCormack, Gillian M Keating, Katherine A Lyseng-Williamso. Insulin lispro: a review of its use in the management of diabetes mellitus. Drugs. vol 67. issue 3. 2007-05-15. PMID:17335298. |
insulin lispro has a faster onset of action and shorter duration of activity than regular human insulin, and the time-action profile of insulin lispro mimics that of the physiological response of endogenous human insulin to food intake. |
2007-05-15 |
2023-08-12 |
human |
| Varman T Samuel, Zhen-Xiang Liu, Amy Wang, Sara A Beddow, John G Geisler, Mario Kahn, Xian-man Zhang, Brett P Monia, Sanjay Bhanot, Gerald I Shulma. Inhibition of protein kinase Cepsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease. The Journal of clinical investigation. vol 117. issue 3. 2007-05-04. PMID:17318260. |
three days of high-fat feeding in rats results specifically in hepatic steatosis and hepatic insulin resistance. |
2007-05-04 |
2023-08-12 |
rat |
| Varman T Samuel, Zhen-Xiang Liu, Amy Wang, Sara A Beddow, John G Geisler, Mario Kahn, Xian-man Zhang, Brett P Monia, Sanjay Bhanot, Gerald I Shulma. Inhibition of protein kinase Cepsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease. The Journal of clinical investigation. vol 117. issue 3. 2007-05-04. PMID:17318260. |
to determine whether pkcepsilon plays a causal role in the pathogenesis of hepatic insulin resistance, we treated rats with an antisense oligonucleotide against pkcepsilon and subjected them to 3 days of high-fat feeding. |
2007-05-04 |
2023-08-12 |
rat |
| Francis B Stephens, Claire E Evans, Dumitru Constantin-Teodosiu, Paul L Greenhaf. Carbohydrate ingestion augments L-carnitine retention in humans. Journal of applied physiology (Bethesda, Md. : 1985). vol 102. issue 3. 2007-04-30. PMID:17138832. |
maintaining hyperinsulinemia (approximately 150 mu/l) during steady-state hypercarnitinemia (approximately 550 micromol/l) increases skeletal muscle total carnitine (tc) content by approximately 15% within 5 h. the present study aimed to investigate whether an increase in whole body carnitine retention can be achieved through l-carnitine feeding in conjunction with a dietary-induced elevation in circulating insulin. |
2007-04-30 |
2023-08-12 |
Not clear |