| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Joëlle Dupont, Sophie Tesseraud, Michel Derouet, Anne Collin, Nicole Rideau, Sabine Crochet, Estelle Godet, Estelle Cailleau-Audouin, Sonia Métayer-Coustard, Michel J Duclos, Christian Gespach, Tom E Porter, Larry A Cogburn, Jean Simo. Insulin immuno-neutralization in chicken: effects on insulin signaling and gene expression in liver and muscle. The Journal of endocrinology. vol 197. issue 3. 2009-07-07. PMID:18492818. |
most plasma parameters and food intake were altered by insulin privation as early as 1 h and largely at 5 h. the initial steps of insulin signaling pathways including insulin receptor (ir), ir substrate-1 (irs-1), and src homology collagen and downstream elements: phosphatidylinositol 3-kinase (pi3k), akt, gsk3, erk2, and s6 ribosomal protein) were accordingly turned off in the liver. |
2009-07-07 |
2023-08-12 |
chicken |
| Claudia Camerin. Low sympathetic tone and obese phenotype in oxytocin-deficient mice. Obesity (Silver Spring, Md.). vol 17. issue 5. 2009-07-07. PMID:19247273. |
in this study, we characterized a murin model deficient in oxt peptide (oxt(-/-)) to evaluate food intake and body weight, glucose tolerance and insulin tolerance, leptin and adrenaline levels. |
2009-07-07 |
2023-08-12 |
mouse |
| Claudia Camerin. Low sympathetic tone and obese phenotype in oxytocin-deficient mice. Obesity (Silver Spring, Md.). vol 17. issue 5. 2009-07-07. PMID:19247273. |
we found that oxt(-/-) mice develop late-onset obesity and hyperleptinemia without any alterations in food intake in addition to having a decreased insulin sensitivity and glucose intolerance. |
2009-07-07 |
2023-08-12 |
mouse |
| P Weyrich, S Albet, R Lammers, F Machicao, A Fritsche, N Stefan, H-U Härin. Genetic variability of procolipase associates with altered insulin secretion in non-diabetic Caucasians. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. vol 117. issue 2. 2009-06-26. PMID:18726866. |
while colipase is an indispensable cofactor for pancreatic lipase, enterostatin acts as a hormone that inhibits insulin secretion and confers satiety signals to the brain, thereby restricting further food intake in animal models. |
2009-06-26 |
2023-08-12 |
Not clear |
| Ambrose A Dunn-Meynell, Nicole M Sanders, Douglas Compton, Thomas C Becker, Jun-ichi Eiki, Bei B Zhang, Barry E Levi. Relationship among brain and blood glucose levels and spontaneous and glucoprivic feeding. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 21. 2009-06-23. PMID:19474328. |
to assess the role of ventromedial hypothalamus (vmh) (arcuate plus ventromedial nucleus) glucosensing neurons as potential mediators of spontaneous and glucoprivic feeding, meal patterns were observed, and blood and vmh microdialysis fluid were sampled in 15 rats every 10 min for 3.5 h after dark onset and 2 h after insulin (5 u/kg, i.v.) |
2009-06-23 |
2023-08-12 |
rat |
| Frédéric Tremblay, Ann-Marie T Richard, Sarah Will, Jameel Syed, Nancy Stedman, Mylène Perreault, Ruth E Gimen. Disruption of G protein-coupled receptor 39 impairs insulin secretion in vivo. Endocrinology. vol 150. issue 6. 2009-06-18. PMID:19213841. |
we have recently shown that young gpr39(-/-) mice have normal body weight, food intake, and fasting glucose and insulin levels. |
2009-06-18 |
2023-08-12 |
mouse |
| James Malone, Michael Trautmann, Ken Wilhelm, Kristin Taylor, David M Kendal. Exenatide once weekly for the treatment of type 2 diabetes. Expert opinion on investigational drugs. vol 18. issue 3. 2009-06-18. PMID:19243286. |
exenatide lowers blood glucose through multiple mechanisms, including enhancement of glucose-dependent insulin secretion, suppression of excess glucagon secretion, reduction of food intake and slowing of gastric emptying. |
2009-06-18 |
2023-08-12 |
Not clear |
| Chin-Hui Su, I-Min Liu, Hsien-Hui Chung, Juei-Tang Chen. Activation of I2-imidazoline receptors by agmatine improved insulin sensitivity through two mechanisms in type-2 diabetic rats. Neuroscience letters. vol 457. issue 3. 2009-06-18. PMID:19429177. |
in an attempt to clarify the role of endogenous opioid in peripheral i2-imidazoline receptors activation for improvement of insulin action, bilateral adrenalectomy was carried out in rats with insulin resistance induced by 4-week fructose-rich chow feeding. |
2009-06-18 |
2023-08-12 |
rat |
| Christopher B Newgard, Jie An, James R Bain, Michael J Muehlbauer, Robert D Stevens, Lillian F Lien, Andrea M Haqq, Svati H Shah, Michelle Arlotto, Cris A Slentz, James Rochon, Dianne Gallup, Olga Ilkayeva, Brett R Wenner, William S Yancy, Howard Eisenson, Gerald Musante, Richard S Surwit, David S Millington, Mark D Butler, Laura P Svetke. A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. Cell metabolism. vol 9. issue 4. 2009-06-15. PMID:19356713. |
despite having reduced food intake and a low rate of weight gain equivalent to the sc group, hf/bcaa rats were as insulin resistant as hf rats. |
2009-06-15 |
2023-08-12 |
rat |
| Christopher B Newgard, Jie An, James R Bain, Michael J Muehlbauer, Robert D Stevens, Lillian F Lien, Andrea M Haqq, Svati H Shah, Michelle Arlotto, Cris A Slentz, James Rochon, Dianne Gallup, Olga Ilkayeva, Brett R Wenner, William S Yancy, Howard Eisenson, Gerald Musante, Richard S Surwit, David S Millington, Mark D Butler, Laura P Svetke. A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. Cell metabolism. vol 9. issue 4. 2009-06-15. PMID:19356713. |
insulin resistance induced by hf/bcaa feeding was accompanied by chronic phosphorylation of mtor, jnk, and irs1ser307 and by accumulation of multiple acylcarnitines in muscle, and it was reversed by the mtor inhibitor, rapamycin. |
2009-06-15 |
2023-08-12 |
rat |
| Jun Ding, Yan Gao, Jing Zhao, Hong Yan, Shi-ying Guo, Qin-xian Zhang, Ling-song Li, Xiang Ga. Pax6 haploinsufficiency causes abnormal metabolic homeostasis by down-regulating glucagon-like peptide 1 in mice. Endocrinology. vol 150. issue 5. 2009-06-08. PMID:19116343. |
finally, administering the glp-1 receptor agonist exendin-4 to pax6(m/+) mice largely reversed their abnormal food intake, glycemic excursion, and insulin secretion. |
2009-06-08 |
2023-08-12 |
mouse |
| P R Flatt, C J Bailey, B D Gree. Recent advances in antidiabetic drug therapies targeting the enteroinsular axis. Current drug metabolism. vol 10. issue 2. 2009-06-04. PMID:19275548. |
the enteroinsular axis (eia) constitutes a physiological signalling system whereby intestinal endocrine cells secrete incretin hormones following feeding that potentiate insulin secretion and contribute to the regulation of blood glucose homeostasis. |
2009-06-04 |
2023-08-12 |
Not clear |
| J F López-Olmeda, M Egea-Alvarez, F J Sánchez-Vázque. Glucose tolerance in fish: Is the daily feeding time important? Physiology & behavior. vol 96. issue 4-5. 2009-05-26. PMID:19150450. |
daily rhythms in glucose tolerance have been reported for several species of mammals, which seem to be linked to factors such as daily rhythms of insulin resistance and feeding habits. |
2009-05-26 |
2023-08-12 |
Not clear |
| H B Vaidya, R K Goya. Glucagon like peptides-1 modulators as newer target for diabetes. Current drug targets. vol 9. issue 10. 2009-05-22. PMID:18855626. |
glucoregulatory actions of glp-1 include glucose-dependent enhancement of insulin secretion, inhibition of glucagon secretion, slowing of gastric emptying and reduction of food intake. |
2009-05-22 |
2023-08-12 |
Not clear |
| Huiyun Liang, Bogdan Balas, Puntip Tantiwong, John Dube, Bret H Goodpaster, Robert M O'Doherty, Ralph A DeFronzo, Arlan Richardson, Nicolas Musi, Walter F War. Whole body overexpression of PGC-1alpha has opposite effects on hepatic and muscle insulin sensitivity. American journal of physiology. Endocrinology and metabolism. vol 296. issue 4. 2009-05-21. PMID:19208857. |
feeding a high-fat diet to tg mice eliminated the increased muscle insulin sensitivity. |
2009-05-21 |
2023-08-12 |
mouse |
| Kamyar Kalantar-Zadeh, Stephen F Derose, Susan Nicholas, Deborah Benner, Kumar Sharma, Csaba P Kovesd. Burnt-out diabetes: impact of chronic kidney disease progression on the natural course of diabetes mellitus. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation. vol 19. issue 1. 2009-05-15. PMID:19121768. |
potential contributors to this so-called "burnt-out diabetes" include decreased renal and hepatic insulin clearance, a decline in renal gluconeogenesis, deficient catecholamine release, diminished food intake (because of anorexia or diabetic gastroparesis), protein-energy wasting (with resultant loss of weight and body fat), and the hypoglycemic effects of dialysis treatment. |
2009-05-15 |
2023-08-12 |
Not clear |
| Harold A Franc. Nutrition and muscle catabolism in maintenance hemodialysis: does feeding make muscle cells selective self-eaters? Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation. vol 19. issue 1. 2009-05-15. PMID:19121779. |
increases in proteolysis with feeding are driven by insulin resistance and the increased oxidative stress of mitochondrial respiration. |
2009-05-15 |
2023-08-12 |
Not clear |
| Craig Lawrence Kie. Dietary interventions for metabolic syndrome: role of modifying dietary fats. Current diabetes reports. vol 9. issue 1. 2009-05-14. PMID:19192424. |
a research challenge is to determine whether feeding humans diets with markedly different contents of pa and oa would alter insulin sensitivity and/or critical biochemical mechanisms impacting muscle insulin signaling. |
2009-05-14 |
2023-08-12 |
Not clear |
| Thomas P J Solomon, Edward S Chambers, Asker E Jeukendrup, Andrew A Toogood, Andrew K Blanni. The effect of feeding frequency on insulin and ghrelin responses in human subjects. The British journal of nutrition. vol 100. issue 4. 2009-05-13. PMID:18394217. |
the effect of feeding frequency on insulin and ghrelin responses in human subjects. |
2009-05-13 |
2023-08-12 |
human |
| Thomas P J Solomon, Edward S Chambers, Asker E Jeukendrup, Andrew A Toogood, Andrew K Blanni. The effect of feeding frequency on insulin and ghrelin responses in human subjects. The British journal of nutrition. vol 100. issue 4. 2009-05-13. PMID:18394217. |
therefore, we investigated the effect of feeding frequency on insulin and ghrelin responses in human subjects. |
2009-05-13 |
2023-08-12 |
human |