| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stéphane Boghossian, Karalee Lemmon, Miejung Park, David A Yor. High-fat diets induce a rapid loss of the insulin anorectic response in the amygdala. American journal of physiology. Regulatory, integrative and comparative physiology. vol 297. issue 5. 2009-12-03. PMID:19726717. |
we conclude that the amygdala may be an important site for insulin regulation of food intake and may have a significant role in determining susceptibility to hfd-induced obesity. |
2009-12-03 |
2023-08-12 |
rat |
| Carmen Mingorance, Maria Gonzalez del Pozo, Maria Dolores Herrera, Maria Alvarez de Sotomayo. Oral supplementation of propionyl-l-carnitine reduces body weight and hyperinsulinaemia in obese Zucker rats. The British journal of nutrition. vol 102. issue 8. 2009-12-02. PMID:19545458. |
plc decreased body-weight gain, food intake, adiposity, insulin serum concentration and tag liver content and improved insulin resistance. |
2009-12-02 |
2023-08-12 |
rat |
| Bhavna Sharma, Rajani Salunke, Swati Srivastava, Chandrajeetbalo Majumder, Partha Ro. Effects of guggulsterone isolated from Commiphora mukul in high fat diet induced diabetic rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 47. issue 10. 2009-12-01. PMID:19635521. |
on feeding the normal rats with fat rich diet they showed increased serum glucose, cholesterol and triglyceride levels along with increase in insulin resistance significantly (p<0.05) in comparison to control animals. |
2009-12-01 |
2023-08-12 |
human |
| James M Shikany, Radhika P Phadke, David T Redden, Barbara A Gowe. Effects of low- and high-glycemic index/glycemic load diets on coronary heart disease risk factors in overweight/obese men. Metabolism: clinical and experimental. vol 58. issue 12. 2009-11-30. PMID:19631353. |
we conducted a randomized crossover feeding study of matched diets differing only in gi and gl in 24 overweight or obese but otherwise healthy men to investigate the effects on insulin sensitivity, inflammation, thrombosis/fibrinolysis, lipoproteins/lipids, and body composition. |
2009-11-30 |
2023-08-12 |
human |
| Stephen J Peterson, Dong Hyun Kim, Ming Li, Vincenzo Positano, Luca Vanella, Luigi F Rodella, Francesco Piccolomini, Nitin Puri, Amalia Gastaldelli, Claudia Kusmic, Antonio L'Abbate, Nader G Abraha. The L-4F mimetic peptide prevents insulin resistance through increased levels of HO-1, pAMPK, and pAKT in obese mice. Journal of lipid research. vol 50. issue 7. 2009-11-23. PMID:19224872. |
food intake, insulin, glucose adipocyte stem cells, pampk, pakt, cb1, and insulin receptor phosphorylation were determined. |
2009-11-23 |
2023-08-12 |
mouse |
| Claire L Cornick, Barbara H Strongitharm, Gary Sassano, Christopher Rawlins, Andrew E Mayes, Alison N Joseph, Jacqueline O'Dowd, Claire Stocker, Ed Wargent, Michael A Cawthorne, A Louise Brown, Jonathan R S Arc. Identification of a novel agonist of peroxisome proliferator-activated receptors alpha and gamma that may contribute to the anti-diabetic activity of guggulipid in Lep(ob)/Lep(ob) mice. The Journal of nutritional biochemistry. vol 20. issue 10. 2009-11-16. PMID:18926687. |
however, the ethyl ester of commipheric acid (150 mg/kg, twice daily) lowered fasting blood glucose and plasma insulin, and plasma triglycerides without affecting food intake or body weight. |
2009-11-16 |
2023-08-12 |
mouse |
| Lowenna J Holt, Ruth J Lyons, Ashleigh S Ryan, Susan M Beale, Andrew Ward, Gregory J Cooney, Roger J Dal. Dual ablation of Grb10 and Grb14 in mice reveals their combined role in regulation of insulin signaling and glucose homeostasis. Molecular endocrinology (Baltimore, Md.). vol 23. issue 9. 2009-11-16. PMID:19541746. |
however, despite the absence of additive effects on insulin signaling and body composition, the double-knockout mice are protected from the impaired glucose tolerance that results from high-fat feeding, whereas protection is not observed with animals deficient for individual adaptors. |
2009-11-16 |
2023-08-12 |
mouse |
| Leona Plum, Hua V Lin, Roxanne Dutia, Jun Tanaka, Kumiko S Aizawa, Michihiro Matsumoto, Andrea J Kim, Niamh X Cawley, Ji-Hye Paik, Y Peng Loh, Ronald A DePinho, Sharon L Wardlaw, Domenico Accil. The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake. Nature medicine. vol 15. issue 10. 2009-11-16. PMID:19767734. |
insulin and leptin inhibit food intake through actions in the central nervous system that are partly mediated by the transcription factor foxo1. |
2009-11-16 |
2023-08-12 |
mouse |
| Itaru Kyoraku, Kazutaka Shiomi, Kenji Kangawa, Masamitsu Nakazat. Ghrelin reverses experimental diabetic neuropathy in mice. Biochemical and biophysical research communications. vol 389. issue 3. 2009-11-13. PMID:19733151. |
ghrelin administration did not alter food intake, body weight gain, blood glucose levels, or plasma insulin levels when compared with mice given saline or desacyl-ghrelin administration. |
2009-11-13 |
2023-08-12 |
mouse |
| Swarup K Chakrabarti, Banumathi K Cole, Yeshao Wen, Susanna R Keller, Jerry L Nadle. 12/15-lipoxygenase products induce inflammation and impair insulin signaling in 3T3-L1 adipocytes. Obesity (Silver Spring, Md.). vol 17. issue 9. 2009-11-05. PMID:19521344. |
because 12/15-lo expression is upregulated in visceral adipocytes by high-fat feeding in vivo and also by addition of palmitic acid in vitro, we propose that 12/15-lo plays a role in promoting inflammation and insulin resistance associated with obesity. |
2009-11-05 |
2023-08-12 |
mouse |
| Erin Keen-Rhinehart, Mina Desai, Michael G Ros. Central insulin sensitivity in male and female juvenile rats. Hormones and behavior. vol 56. issue 3. 2009-11-04. PMID:19460379. |
in adults, central insulin administration decreases hypothalamic orexigenic neuropeptides, food intake and body weight more effectively in males than females. |
2009-11-04 |
2023-08-12 |
rat |
| Erin Keen-Rhinehart, Mina Desai, Michael G Ros. Central insulin sensitivity in male and female juvenile rats. Hormones and behavior. vol 56. issue 3. 2009-11-04. PMID:19460379. |
therefore, we sought to determine if central insulin treatment in juvenile rats (4 wk) would have similar sex-dependent effects on food intake as those reported in adult rats. |
2009-11-04 |
2023-08-12 |
rat |
| Erin Keen-Rhinehart, Mina Desai, Michael G Ros. Central insulin sensitivity in male and female juvenile rats. Hormones and behavior. vol 56. issue 3. 2009-11-04. PMID:19460379. |
twenty-four hour food intake was measured following icv saline or insulin (0.01 or 0.1 u) prior to the onset of dark phase of the light cycle. |
2009-11-04 |
2023-08-12 |
rat |
| Erin Keen-Rhinehart, Mina Desai, Michael G Ros. Central insulin sensitivity in male and female juvenile rats. Hormones and behavior. vol 56. issue 3. 2009-11-04. PMID:19460379. |
in both males and females, insulin reduced meal size initially (first 4 h) and later decreased meal frequency (4-24 h) to reduce cumulative food intake. |
2009-11-04 |
2023-08-12 |
rat |
| Johannes Erdmann, Yvonne Hebeisen, Florian Lippl, Stefan Wagenpfeil, Volker Schusdziarr. Food intake and plasma ghrelin response during potato-, rice- and pasta-rich test meals. European journal of nutrition. vol 46. issue 4. 2009-11-02. PMID:17497076. |
complex carbohydrates such as potato, rice and pasta are frequently consumed accompaniments of meat meals and have different effects on satiety, food intake, glucose, and insulin concentrations. |
2009-11-02 |
2023-08-12 |
Not clear |
| T Yamauchi, T Kadowak. Physiological and pathophysiological roles of adiponectin and adiponectin receptors in the integrated regulation of metabolic and cardiovascular diseases. International journal of obesity (2005). vol 32 Suppl 7. 2009-10-29. PMID:19136982. |
further conclusions are that decreased adiponectin action and increased monocyte chemoattractant protein-1 (mcp-1) form a vicious adipokine network causing obesity-linked insulin resistance and metabolic syndrome; ppargamma upregulates hmw adiponectin and pparalpha upregulates adipors; that dietary osmotin can serve as a naturally occurring adiponectin receptor agonist; and finally, that under starvation conditions, mmw adiponectin activates ampk in hypothalamus, and promotes food intake, and at the same time hmw adiponectin activates ampk in peripheral tissues, such as skeletal muscle, and stimulates fatty-acids combustion. |
2009-10-29 |
2023-08-12 |
Not clear |
| Geng-Ruei Chang, Ying-Ying Wu, Yi-Shin Chiu, Wen-Ying Chen, Jiunn-Wang Liao, Hong-Ming Hsu, Te-Hsin Chao, Siu-Wan Hung, Frank Chiahung Ma. Long-term administration of rapamycin reduces adiposity, but impairs glucose tolerance in high-fat diet-fed KK/HlJ mice. Basic & clinical pharmacology & toxicology. vol 105. issue 3. 2009-10-28. PMID:19496779. |
however, treated mice had higher serum insulin levels and food intake. |
2009-10-28 |
2023-08-12 |
mouse |
| A Mori, T Sato, P Lee, M Furuuchi, H Tazaki, K Katayama, H Mizutani, T Sako, T Ara. Clinical significance of plasma mannose concentrations in healthy and diabetic dogs. Veterinary research communications. vol 33. issue 5. 2009-10-21. PMID:19083115. |
circulating plasma mannose levels decreased after feeding in both control and diabetic animals in spite of observed insulin level differences. |
2009-10-21 |
2023-08-12 |
Not clear |
| Peter Kovacs, Andras Hajna. In vivo electrophysiological effects of insulin in the rat brain. Neuropeptides. vol 43. issue 4. 2009-10-14. PMID:19541365. |
brain insulin has widespread metabolic, neurotrophic, and neuromodulatory functions and is involved in the central regulation of food intake and body weight, learning and memory, neuronal development, neuronal apoptosis, and aging. |
2009-10-14 |
2023-08-12 |
rat |
| Soo Lim, Sun Young Ahn, In Chan Song, Myung Hee Chung, Hak Chul Jang, Kyong Soo Park, Ki-Up Lee, Youngmi Kim Pak, Hong Kyu Le. Chronic exposure to the herbicide, atrazine, causes mitochondrial dysfunction and insulin resistance. PloS one. vol 4. issue 4. 2009-10-09. PMID:19365547. |
chronic administration of atz decreased basal metabolic rate, and increased body weight, intra-abdominal fat and insulin resistance without changing food intake or physical activity level. |
2009-10-09 |
2023-08-12 |
rat |