| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Silvia Alboni, Maria Vittoria Micioni Di Bonaventura, Cristina Benatti, Maria Elena Giusepponi, Nicoletta Brunello, Carlo Cifan. Hypothalamic expression of inflammatory mediators in an animal model of binge eating. Behavioural brain research. vol 320. 2017-12-27. PMID:27984048. |
considering the role of this region of the hypothalamus in controlling feeding related behavior, this can be relevant in eating disorders and obesity. |
2017-12-27 |
2023-08-13 |
Not clear |
| Hazel Wright, Xiaoyun Li, Nicholas B Fallon, Rebecca Crookall, Timo Giesbrecht, Anna Thomas, Jason C G Halford, Joanne Harrold, Andrej Stanca. Differential effects of hunger and satiety on insular cortex and hypothalamic functional connectivity. The European journal of neuroscience. vol 43. issue 9. 2017-12-22. PMID:26790868. |
the insula and hypothalamus appear to form a homeostatic energy balance network related to cognitive control of eating; prompting eating and preventing overeating when energy is depleted, and ending feeding or transferring attention away from food upon satiation. |
2017-12-22 |
2023-08-13 |
human |
| Ji Liu, Kristie Conde, Peng Zhang, Varoth Lilascharoen, Zihui Xu, Byung Kook Lim, Randy J Seeley, J Julius Zhu, Michael M Scott, Zhiping P Pan. Enhanced AMPA Receptor Trafficking Mediates the Anorexigenic Effect of Endogenous Glucagon-like Peptide-1 in the Paraventricular Hypothalamus. Neuron. vol 96. issue 4. 2017-12-22. PMID:29056294. |
glucagon-like peptide 1 (glp-1)-expressing neurons in the hindbrain send robust projections to the paraventricular nucleus of the hypothalamus (pvn), which is involved in the regulation of food intake. |
2017-12-22 |
2023-08-13 |
Not clear |
| Eun Ran Kim, Pei San Lew, Alexandra Spirkina, Tooru M Mizun. Xenin-induced feeding suppression is not mediated through the activation of central extracellular signal-regulated kinase signaling in mice. Behavioural brain research. vol 312. 2017-12-19. PMID:27316340. |
xenin is a gut hormone that reduces food intake by partly acting through the hypothalamus via neurotensin receptor 1 (ntsr1). |
2017-12-19 |
2023-08-13 |
mouse |
| Sandra Aparecida Benite-Ribeiro, David Alan Putt, Marlos Cruzeiro Soares-Filho, Júlia Matzenbacher Santo. The link between hypothalamic epigenetic modifications and long-term feeding control. Appetite. vol 107. 2017-12-19. PMID:27565376. |
therefore, this review discusses the recent reports that link epigenetic modifications in the hypothalamus to changes on long-term feeding control and its role in the onset of obesity. |
2017-12-19 |
2023-08-13 |
Not clear |
| Su Yang, Huiming Yang, Renbao Chang, Peng Yin, Yang Yang, Weili Yang, Shanshan Huang, Marta A Gaertig, Shihua Li, Xiao-Jiang L. MANF regulates hypothalamic control of food intake and body weight. Nature communications. vol 8. issue 1. 2017-12-18. PMID:28924165. |
the hypothalamus has a vital role in controlling food intake and energy homeostasis; its activity is modulated by neuropeptides and endocrine factors. |
2017-12-18 |
2023-08-13 |
mouse |
| Jonathan H Wardman, Ivone Gomes, Erin N Bobeck, Jennifer A Stockert, Abhijeet Kapoor, Paola Bisignano, Achla Gupta, Mihaly Mezei, Sanjai Kumar, Marta Filizola, Lakshmi A Dev. Identification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake. Science signaling. vol 9. issue 430. 2017-12-05. PMID:27245612. |
several neuropeptide systems in the hypothalamus, including neuropeptide y and agouti-related protein (agrp), control food intake. |
2017-12-05 |
2023-08-13 |
mouse |
| Jonathan H Wardman, Ivone Gomes, Erin N Bobeck, Jennifer A Stockert, Abhijeet Kapoor, Paola Bisignano, Achla Gupta, Mihaly Mezei, Sanjai Kumar, Marta Filizola, Lakshmi A Dev. Identification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake. Science signaling. vol 9. issue 430. 2017-12-05. PMID:27245612. |
peripheral injection of ms0015203 into mice increased food intake and body weight, and these responses were significantly attenuated in mice with decreased expression of gpr171 in the hypothalamus. |
2017-12-05 |
2023-08-13 |
mouse |
| Takeshi Iwasa, Toshiya Matsuzaki, Altankhuu Tungalagsuvd, Munkhsaikhan Munkhzaya, Mayila Yiliyasi, Takeshi Kato, Akira Kuwahara, Minoru Irahar. Effects of chronic testosterone administration on body weight and food intake differ among pre-pubertal, gonadal-intact, and ovariectomized female rats. Behavioural brain research. vol 309. 2017-11-21. PMID:27139935. |
these results indicate that the effects of testosterone on body weight and appetite differed among ages and/or estrogen milieu in female rats, and that attenuation of estrogens' actions on the hypothalamus might be partly involved in the androgen-induced increases of body weight gain and food intake in females. |
2017-11-21 |
2023-08-13 |
rat |
| Ling Shen, Chunmin C Lo, Laura A Woollett, Min Li. Apolipoprotein A-IV exerts its anorectic action through a PI3K/Akt signaling pathway in the hypothalamus. Biochemical and biophysical research communications. vol 494. issue 1-2. 2017-11-21. PMID:29037812. |
we found that apoa-iv significantly reduced food intake and activated pi3k signaling in the hypothalamus, and these effects were abolished by icv pre-treatment with ly294002. |
2017-11-21 |
2023-08-13 |
rat |
| b' B Mikul\\xc3\\xa1\\xc5\\xa1kov\\xc3\\xa1, L Malet\\xc3\\xadnsk\\xc3\\xa1, J Zicha, J Kune\\xc5\\xa. The role of food intake regulating peptides in cardiovascular regulation. Molecular and cellular endocrinology. vol 436. 2017-11-17. PMID:27450151.' |
moreover, it is important to know that the hypothalamus together with the brainstem seem to be major structures in the regulation of food intake and blood pressure. |
2017-11-17 |
2023-08-13 |
Not clear |
| Vagner Ramon Rodrigues Silva, Carlos Kiyoshi Katashima, Carla G Bueno Silva, Luciene Lenhare, Thayana Oliveira Micheletti, Rafael Ludemann Camargo, Ana Carolina Ghezzi, Juliana Alves Camargo, Alexandre Moura Assis, Natalia Tobar, Joseane Morari, Daniela S Razolli, Leandro Pereira Moura, José Rodrigo Pauli, Dennys Esper Cintra, Lício Augusto Velloso, Mario J A Saad, Eduardo Rochete Ropell. Hypothalamic S1P/S1PR1 axis controls energy homeostasis in Middle-Aged Rodents: the reversal effects of physical exercise. Aging. vol 9. issue 1. 2017-11-16. PMID:28039439. |
acutely, exercise increased sphingosine-1-phosphate (s1p) levels in the cerebrospinal fluid (csf) of young rats, whereas the administration of csf from exercised young rats into the hypothalamus of middle-aged rats at rest was sufficient to reduce the food intake. |
2017-11-16 |
2023-08-13 |
mouse |
| Tae Seok Oh, Hanchae Cho, Jae Hyun Cho, Seong-Woon Yu, Eun-Kyoung Ki. Hypothalamic AMPK-induced autophagy increases food intake by regulating NPY and POMC expression. Autophagy. vol 12. issue 11. 2017-11-13. PMID:27533078. |
moreover, ampk knockdown in the arcuate nucleus of the hypothalamus decreased autophagic activity and changed npy and pomc expression, leading to a reduction in food intake and body weight. |
2017-11-13 |
2023-08-13 |
mouse |
| Elsie Tachie Mensah, Ayelén Melisa Blanco, Andrew Donini, Suraj Unniappa. Brain and intestinal expression of galanin-like peptide (GALP), galanin receptor R1 and galanin receptor R2, and GALP regulation of food intake in goldfish (Carassius auratus). Neuroscience letters. vol 637. 2017-10-31. PMID:27884736. |
galanin-like peptide (galp) is a 60 amino acid neuropeptide originally discovered from porcine hypothalamus, and is involved in the regulation of food intake in mammals. |
2017-10-31 |
2023-08-13 |
Not clear |
| b' Gerard Aragon\\xc3\\xa8s, Andrea Ardid-Ruiz, Maria Ibars, Manuel Su\\xc3\\xa1rez, Cinta Blad\\xc3\\xa. Modulation of leptin resistance by food compounds. Molecular nutrition & food research. vol 60. issue 8. 2017-10-23. PMID:26842874.' |
leptin is mainly secreted by white adipose tissue and regulates energy homeostasis by inhibiting food intake and stimulating energy expenditure through its action in neuronal circuits in the brain, particularly in the hypothalamus. |
2017-10-23 |
2023-08-13 |
Not clear |
| Stefano Schiaffino, Bert Blaauw, Kenneth A Dya. The functional significance of the skeletal muscle clock: lessons from Skeletal muscle. vol 6. 2017-10-23. PMID:27752300. |
the functional significance of the skeletal muscle clock: lessons from the circadian oscillations of muscle genes are controlled either directly by the intrinsic muscle clock or by extrinsic factors, such as feeding, hormonal signals, or neural influences, which are in turn regulated by the central pacemaker, the suprachiasmatic nucleus of the hypothalamus. |
2017-10-23 |
2023-08-13 |
Not clear |
| Alexander Edwards, Alfonso Abizai. Driving the need to feed: Insight into the collaborative interaction between ghrelin and endocannabinoid systems in modulating brain reward systems. Neuroscience and biobehavioral reviews. vol 66. 2017-10-18. PMID:27136126. |
this review documents the relationship between ghrelin and endocannabinoid systems within the periphery and hypothalamus (hyp) before presenting evidence suggesting that these two systems likewise work collaboratively within the ventral tegmental area (vta) to modulate non-homeostatic feeding. |
2017-10-18 |
2023-08-13 |
Not clear |
| Yuko Maejima, Kensuke Kumamoto, Seiichi Takenoshita, Kenju Shimomur. Projections from a single NUCB2/nesfatin-1 neuron in the paraventricular nucleus to different brain regions involved in feeding. Brain structure & function. vol 221. issue 9. 2017-10-13. PMID:26639940. |
functionally, nucb2/nesfatin-1 neurons in the pvn regulate feeding through the hypothalamus and brain stem. |
2017-10-13 |
2023-08-13 |
Not clear |
| Tae Seok Oh, Yoonjeong Jeon, Seolsong Kim, Eun-Kyoung Ki. Hypothalamic AMP-activated Protein Kinase as a Regulator of Food Intake and Energy Balance. CNS & neurological disorders drug targets. vol 15. issue 8. 2017-10-10. PMID:27577738. |
recent evidence suggests that different hormones, nutrients and synthetic chemicals can modulate ampk activity in the hypothalamus, thereby regulating food intake and body weight, through neuropeptide expressions. |
2017-10-10 |
2023-08-13 |
Not clear |
| Suat Tekin, Yavuz Erden, Fatma Ozyalin, Yilmaz Cigremis, Cemil Colak, Suleyman Sanda. The effects of intracerebroventricular infusion of irisin on feeding behaviour in rats. Neuroscience letters. vol 645. 2017-10-10. PMID:28242329. |
results indicates that long-term irisin treatment increases food intake without increasing body weight associated with increased ghrelin, npy and ucp2 mrnas, and decreased leptin and pomc mrna in the hypothalamus. |
2017-10-10 |
2023-08-13 |
rat |