| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| He-Ren Gao, Qian-Xing Zhuang, Yong-Xiao Zhang, Zhang-Peng Chen, Bin Li, Xiao-Yang Zhang, Yi-Ting Zhong, Jian-Jun Wang, Jing-Ning Zh. Orexin Directly Enhances the Excitability of Globus Pallidus Internus Neurons in Rat by Co-activating OX1 and OX2 Receptors. Neuroscience bulletin. vol 33. issue 4. 2018-04-17. PMID:28389870. |
orexin, released from the hypothalamus, has been implicated in various basic non-somatic functions including feeding, the sleep-wakefulness cycle, emotion, and cognition. |
2018-04-17 |
2023-08-13 |
rat |
| Wil Sims, Jiaqing Yi, Mark A Cline, Elizabeth R Gilber. Central injection of a synthetic chicken partial leptin peptide does not affect food intake in chicks. Neuroscience letters. vol 656. 2018-04-05. PMID:28751205. |
leptin is an adipose tissue-derived hormone in mammals that plays an important role in whole body energy balance via its inhibitory effects on food intake mediated through the hypothalamus. |
2018-04-05 |
2023-08-13 |
chicken |
| Lars Paeger, Ismene Karakasilioti, Janine Altmüller, Peter Frommolt, Jens Brüning, Peter Kloppenbur. Antagonistic modulation of NPY/AgRP and POMC neurons in the arcuate nucleus by noradrenalin. eLife. vol 6. 2018-02-26. PMID:28632132. |
in the arcuate nucleus of the hypothalamus (arh) satiety signaling (anorexigenic) pro-opiomelanocortin (pomc)-expressing and hunger signaling (orexigenic) agouti-related peptide (agrp)-expressing neurons are key components of the neuronal circuits that control food intake and energy homeostasis. |
2018-02-26 |
2023-08-13 |
mouse |
| Eva Tudurí, Daniel Beiroa, Johannes Stegbauer, Johan Fernø, Miguel López, Carlos Diéguez, Rubén Nogueira. Acute stimulation of brain mu opioid receptors inhibits glucose-stimulated insulin secretion via sympathetic innervation. Neuropharmacology. vol 110. issue Pt A. 2018-02-22. PMID:27511839. |
opioid receptors are also expressed in multiple brain regions including the hypothalamus, where they play a role in feeding behavior and energy homeostasis, but their potential role in central regulation of glucose metabolism is unknown. |
2018-02-22 |
2023-08-13 |
mouse |
| D L McCue, J M Kasper, J D Homme. Regulation of motivation for food by neuromedin U in the paraventricular nucleus and the dorsal raphe nucleus. International journal of obesity (2005). vol 41. issue 1. 2018-02-16. PMID:27748746. |
although these effects of nmu have primarily been attributed to signaling in the paraventricular nucleus of the hypothalamus (pvn), nmu has also been found in other brain regions involved in both feeding behavior and motivation. |
2018-02-16 |
2023-08-13 |
Not clear |
| Cristina Russo, Antonella Russo, Rosario Gulino, Rosalia Pellitteri, Stefania Stanzan. Effects of different musical frequencies on NPY and Ghrelin secretion in the rat hypothalamus. Brain research bulletin. vol 132. 2018-02-09. PMID:28599876. |
hypothalamus appears to integrate the orexigenic properties of a novel peptide, ghrelin (ghre) that induces food intake through neuropeptide y (npy). |
2018-02-09 |
2023-08-13 |
rat |
| Cristina Russo, Antonella Russo, Rosario Gulino, Rosalia Pellitteri, Stefania Stanzan. Effects of different musical frequencies on NPY and Ghrelin secretion in the rat hypothalamus. Brain research bulletin. vol 132. 2018-02-09. PMID:28599876. |
ghre stimulates appetite by acting on the ventral hypothalamus, which controls food intake. |
2018-02-09 |
2023-08-13 |
rat |
| M P Cornejo, S T Hentges, M Maliqueo, H Coirini, D Becu-Villalobos, C F Elia. Neuroendocrine Regulation of Metabolism. Journal of neuroendocrinology. vol 28. issue 7. 2018-02-08. PMID:27114114. |
among the nuclei that comprise the hypothalamus, the arcuate nucleus is one of the major mediators in the regulation of food intake. |
2018-02-08 |
2023-08-13 |
Not clear |
| Janel M Hagar, Victoria A Macht, Steven P Wilson, James R Fade. Upregulation of orexin/hypocretin expression in aged rats: Effects on feeding latency and neurotransmission in the insular cortex. Neuroscience. vol 350. 2018-02-06. PMID:28344067. |
aging is associated with changes in numerous homeostatic functions, such as food intake, that are thought to be mediated by the hypothalamus. |
2018-02-06 |
2023-08-13 |
rat |
| Janel M Hagar, Victoria A Macht, Steven P Wilson, James R Fade. Upregulation of orexin/hypocretin expression in aged rats: Effects on feeding latency and neurotransmission in the insular cortex. Neuroscience. vol 350. 2018-02-06. PMID:28344067. |
orexin/hypocretin neurons of the hypothalamus regulate several physiological functions, including feeding, sleep and wakefulness. |
2018-02-06 |
2023-08-13 |
rat |
| b' Ivana Grkovi\\xc4\\x87, Ivana Bjelobaba, Nata\\xc5\\xa1a Mitrovi\\xc4\\x87, Irena Lavrnja, Dunja Drakuli\\xc4\\x87, Jelena Martinovi\\xc4\\x87, Milo\\xc5\\xa1 Stanojlovi\\xc4\\x87, Anica Horvat, Nade\\xc5\\xbeda Nedeljkovi\\xc4\\x8. Expression of ecto-nucleoside triphosphate diphosphohydrolase3 (NTPDase3) in the female rat brain during postnatal development. Journal of chemical neuroanatomy. vol 77. 2018-01-31. PMID:27049676.' |
prominent enhancement of ntpdase3-ir in the hypothalamus coincides with age when animals acquire diurnal rhythms of sleeping and feeding, supporting the hypothesis that this enzyme may be involved in regulation of homeostatic functions. |
2018-01-31 |
2023-08-13 |
rat |
| Dollada Srisai, Terry C Yin, Abigail A Lee, Alix A J Rouault, Nicole A Pearson, Justin L Grobe, Julien A Seba. MRAP2 regulates ghrelin receptor signaling and hunger sensing. Nature communications. vol 8. issue 1. 2018-01-23. PMID:28959025. |
it is primarily secreted by the stomach and acts at its receptor, the growth hormone secretagogue receptor 1a (ghsr1a), in the hypothalamus to signal hunger and promote food intake. |
2018-01-23 |
2023-08-13 |
mouse |
| Jesus Pujol, Laura Blanco-Hinojo, Ramón Coronas, Susanna Esteba-Castillo, Mercedes Rigla, Gerard Martínez-Vilavella, Joan Deus, Ramón Novell, Assumpta Caixà. Mapping the sequence of brain events in response to disgusting food. Human brain mapping. vol 39. issue 1. 2018-01-23. PMID:29024175. |
a subsequent core phase was characterized by the activation of subcortical and cortical structures directly concerned not only with the emotional dimension of disgust (e.g., amygdala-hippocampus, insula), but also with the regulation of food intake (e.g., hypothalamus). |
2018-01-23 |
2023-08-13 |
human |
| R Saito, M So, Y Motojima, T Matsuura, M Yoshimura, H Hashimoto, Y Yamamoto, K Kusuhara, Y Uet. Activation of Nesfatin-1-Containing Neurones in the Hypothalamus and Brainstem by Peripheral Administration of Anorectic Hormones and Suppression of Feeding via Central Nesfatin-1 in Rats. Journal of neuroendocrinology. vol 28. issue 9. 2018-01-16. PMID:27203571. |
activation of nesfatin-1-containing neurones in the hypothalamus and brainstem by peripheral administration of anorectic hormones and suppression of feeding via central nesfatin-1 in rats. |
2018-01-16 |
2023-08-13 |
rat |
| R Saito, M So, Y Motojima, T Matsuura, M Yoshimura, H Hashimoto, Y Yamamoto, K Kusuhara, Y Uet. Activation of Nesfatin-1-Containing Neurones in the Hypothalamus and Brainstem by Peripheral Administration of Anorectic Hormones and Suppression of Feeding via Central Nesfatin-1 in Rats. Journal of neuroendocrinology. vol 28. issue 9. 2018-01-16. PMID:27203571. |
administration of glp-1 and cck-8 and co-administrations of glp-1 and leptin at subthreshold doses as confirmed by measurement of food intake, on nesfatin-1-immunoreactive (-ir) neurones in the hypothalamus and brainstem of rats by fos immunohistochemistry. |
2018-01-16 |
2023-08-13 |
rat |
| Claire Bainier, Maria Mateo, Marie-Paule Felder-Schmittbuhl, Jorge Mendoz. Circadian rhythms of hedonic drinking behavior in mice. Neuroscience. vol 349. 2018-01-16. PMID:28286126. |
in mammals, the suprachiasmatic nucleus (scn) of the hypothalamus is the site of the main circadian clock, synchronized by the light-dark cycle, which generates behavioral rhythms like feeding, drinking and activity. |
2018-01-16 |
2023-08-13 |
mouse |
| Sara Carmo-Silva, Clevio Nobrega, Luís Pereira de Almeida, Claudia Cavada. Unraveling the Role of Ataxin-2 in Metabolism. Trends in endocrinology and metabolism: TEM. vol 28. issue 4. 2018-01-12. PMID:28117213. |
ataxin-2 is highly expressed in various tissues including the hypothalamus, a brain region that controls food intake and energy balance. |
2018-01-12 |
2023-08-13 |
Not clear |
| Yuko Maejima, Shinichi Takahashi, Katsuya Takasu, Seiichi Takenoshita, Yoichi Ueta, Kenju Shimomur. Orexin action on oxytocin neurons in the paraventricular nucleus of the hypothalamus. Neuroreport. vol 28. issue 6. 2018-01-10. PMID:28338525. |
oxytocin neurons in the paraventricular nucleus (pvn) of the hypothalamus play an important role in food intake regulation. |
2018-01-10 |
2023-08-13 |
rat |
| Patrick Sweeney, Yong Qi, Zhenping Xu, Yunlei Yan. Activation of hypothalamic astrocytes suppresses feeding without altering emotional states. Glia. vol 64. issue 12. 2018-01-05. PMID:27658520. |
in the present study, by taking advantage of spatiotemporally precise optogenetic approaches, real-time measurements of extracellular adenosine, and behavioral assays, we find that optogenetic stimulation of astrocytes localized in the medial basal hypothalamus (mbh) suppresses food intake in a frequency dependent manner with high frequency, but not low frequency, stimulation of astrocytes reducing food intake. |
2018-01-05 |
2023-08-13 |
Not clear |
| Nick Jikomes, Rohan N Ramesh, Yael Mandelblat-Cerf, Mark L Anderman. Preemptive Stimulation of AgRP Neurons in Fed Mice Enables Conditioned Food Seeking under Threat. Current biology : CB. vol 26. issue 18. 2017-12-27. PMID:27568593. |
agouti-related peptide (agrp) neurons in the arcuate nucleus of the hypothalamus are critical for homeostatic feeding behavior. |
2017-12-27 |
2023-08-13 |
mouse |