| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J C Erickson, K E Clegg, R D Palmite. Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y. Nature. vol 381. issue 6581. 1996-07-03. PMID:8632796. |
we report here that mice deficient for npy have normal food intake and body weight, and become hyperphagic following food deprivation. |
1996-07-03 |
2023-08-12 |
mouse |
| J C Erickson, K E Clegg, R D Palmite. Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y. Nature. vol 381. issue 6581. 1996-07-03. PMID:8632796. |
these results indicate that npy is not essential for certain feeding responses or leptin actions but is an important modulator of excitability in the central nervous system. |
1996-07-03 |
2023-08-12 |
mouse |
| R J Seeley, S C Benoit, T L Davidso. Discriminative cues produced by NPY do not generalize to the interoceptive cues produced by food deprivation. Physiology & behavior. vol 58. issue 6. 1996-06-14. PMID:8623026. |
exogenous administration of neuropeptide y (npy) into the third ventricle causes a rapid and robust feeding response in sated rats. |
1996-06-14 |
2023-08-12 |
rat |
| R J Seeley, S C Benoit, T L Davidso. Discriminative cues produced by NPY do not generalize to the interoceptive cues produced by food deprivation. Physiology & behavior. vol 58. issue 6. 1996-06-14. PMID:8623026. |
this outcome indicates that interoceptive stimuli produced by npy are no more similar to internal cues produced by 24-h food deprivation than to the stimulus consequences of ad lib feeding. |
1996-06-14 |
2023-08-12 |
rat |
| S Dryden, Q Wang, H M Frankish, L Pickavance, G William. The serotonin (5-HT) antagonist methysergide increases neuropeptide Y (NPY) synthesis and secretion in the hypothalamus of the rat. Brain research. vol 699. issue 1. 1996-06-12. PMID:8616599. |
methysergide is a 5-ht antagonist which stimulates feeding in rats and increases npy levels in the hypothalamus. |
1996-06-12 |
2023-08-12 |
rat |
| S Dryden, Q Wang, H M Frankish, L Pickavance, G William. The serotonin (5-HT) antagonist methysergide increases neuropeptide Y (NPY) synthesis and secretion in the hypothalamus of the rat. Brain research. vol 699. issue 1. 1996-06-12. PMID:8616599. |
we conclude that methysergide induced feeding is associated with increased activity of the npy neurons in the arc-pvn projection. |
1996-06-12 |
2023-08-12 |
rat |
| M W Schwartz, D G Baskin, T R Bukowski, J L Kuijper, D Foster, G Lasser, D E Prunkard, D Porte, S C Woods, R J Seeley, D S Weigl. Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice. Diabetes. vol 45. issue 4. 1996-05-13. PMID:8603777. |
five daily intraperitoneal injections of recombinant mouse leptin (150 micrograms) in ob/ob mice lowered food intake by 56% (p < 0.05), body weight by 4.1% (p < 0.05), and levels of npy mrna in the hypothalamic arcuate nucleus by 42.3% (p < 0.05) as compared with saline-treated controls. |
1996-05-13 |
2023-08-12 |
mouse |
| M W Schwartz, D G Baskin, T R Bukowski, J L Kuijper, D Foster, G Lasser, D E Prunkard, D Porte, S C Woods, R J Seeley, D S Weigl. Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice. Diabetes. vol 45. issue 4. 1996-05-13. PMID:8603777. |
leptin administration was also without effect on food intake, body weight, or npy mrna levels in the arcuate nucleus of db/db mice. |
1996-05-13 |
2023-08-12 |
mouse |
| D Richar. Exercise and the neurobiological control of food intake and energy expenditure. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. vol 19 Suppl 4. 1996-03-21. PMID:8581100. |
it is likely that the crh and npy neuropeptidergic systems exert some degree of control on food intake and energy expenditure. |
1996-03-21 |
2023-08-12 |
Not clear |
| B Xu, B H Li, N E Rowland, S P Kalr. Neuropeptide Y injection into the fourth cerebroventricle stimulates c-Fos expression in the paraventricular nucleus and other nuclei in the forebrain: effect of food consumption. Brain research. vol 698. issue 1-2. 1996-03-20. PMID:8581487. |
injection of neuropeptide y (npy) into the cerebroventricular system of the rat results in a robust feeding response. |
1996-03-20 |
2023-08-12 |
rat |
| B Xu, B H Li, N E Rowland, S P Kalr. Neuropeptide Y injection into the fourth cerebroventricle stimulates c-Fos expression in the paraventricular nucleus and other nuclei in the forebrain: effect of food consumption. Brain research. vol 698. issue 1-2. 1996-03-20. PMID:8581487. |
in this study, we observed that npy injection into the fourth ventricle augmented feeding and fos-like immunoreactivity (fli) in the paraventricular nucleus (pvn) and in other neighboring nuclei in the forebrain previously implicated in stimulation of feeding. |
1996-03-20 |
2023-08-12 |
rat |
| B Xu, B H Li, N E Rowland, S P Kalr. Neuropeptide Y injection into the fourth cerebroventricle stimulates c-Fos expression in the paraventricular nucleus and other nuclei in the forebrain: effect of food consumption. Brain research. vol 698. issue 1-2. 1996-03-20. PMID:8581487. |
since the rostral transport of npy in cerebrospinal fluid after injection into the fourth ventricle is unlikely and the topography of fli as well as feeding behavior seen in this study are similar to those observed previously after npy injection into the lateral cerebroventricle, these findings are in accord with the view that feeding induced by npy injection into the fourth ventricle may also be mediated by npy receptive elements in the forebrain. |
1996-03-20 |
2023-08-12 |
rat |
| M Heilig, E Widerlö. Neurobiology and clinical aspects of neuropeptide Y. Critical reviews in neurobiology. vol 9. issue 2-3. 1996-03-20. PMID:8581979. |
a combination of basic and clinical studies has made it possible to circumvent some of these difficulties and provides evidence for a role of npy in the control of endocrine hypothalamic and pituitary functions, in hypothalamic control of food intake and circadian rhythm, and in limbic emotional integration. |
1996-03-20 |
2023-08-12 |
Not clear |
| M Heili. Antisense inhibition of neuropeptide Y (NPY)-Y1 receptor expression blocks the anxiolytic-like action of NPY in amygdala and paradoxically increases feeding. Regulatory peptides. vol 59. issue 2. 1996-03-15. PMID:8584755. |
antisense inhibition of neuropeptide y (npy)-y1 receptor expression blocks the anxiolytic-like action of npy in amygdala and paradoxically increases feeding. |
1996-03-15 |
2023-08-12 |
rat |
| M Heili. Antisense inhibition of neuropeptide Y (NPY)-Y1 receptor expression blocks the anxiolytic-like action of NPY in amygdala and paradoxically increases feeding. Regulatory peptides. vol 59. issue 2. 1996-03-15. PMID:8584755. |
two prominent actions of centrally administered neuropeptide y (npy) are to reduce experimental anxiety and to increase food intake. |
1996-03-15 |
2023-08-12 |
rat |
| M Heili. Antisense inhibition of neuropeptide Y (NPY)-Y1 receptor expression blocks the anxiolytic-like action of NPY in amygdala and paradoxically increases feeding. Regulatory peptides. vol 59. issue 2. 1996-03-15. PMID:8584755. |
antisense inhibition of y1 receptor expression has confirmed an anxiolytic action of endogenous npy, but has not been used to examine its anatomical mediation, or to address whether y1 receptors are involved in the feeding effects of npy. |
1996-03-15 |
2023-08-12 |
rat |
| M Heili. Antisense inhibition of neuropeptide Y (NPY)-Y1 receptor expression blocks the anxiolytic-like action of NPY in amygdala and paradoxically increases feeding. Regulatory peptides. vol 59. issue 2. 1996-03-15. PMID:8584755. |
a heterogeneity of npy receptors mediating anxiolysis and feeding may prove beneficial for drug development efforts. |
1996-03-15 |
2023-08-12 |
rat |
| M G Hulsey, C M Pless, B D White, R J Marti. ICV administration of anti-NPY antisense oligonucleotide: effects on feeding behavior, body weight, peptide content and peptide release. Regulatory peptides. vol 59. issue 2. 1996-03-15. PMID:8584756. |
neuropeptide-y (npy) is a potent stimulator of feeding, and chronic administration of the peptide has been shown to increase body weight. |
1996-03-15 |
2023-08-12 |
rat |
| M G Hulsey, C M Pless, B D White, R J Marti. ICV administration of anti-NPY antisense oligonucleotide: effects on feeding behavior, body weight, peptide content and peptide release. Regulatory peptides. vol 59. issue 2. 1996-03-15. PMID:8584756. |
this study determined the chronic effects of repeated daily injections of an antisense phosphorothioate oligonucleotide complementary to the rat mrna for npy (anpy) on food intake, feeding behavior and body weight change in rats. |
1996-03-15 |
2023-08-12 |
rat |
| D D Pierroz, C Catzeflis, A C Aebi, J E Rivier, M L Auber. Chronic administration of neuropeptide Y into the lateral ventricle inhibits both the pituitary-testicular axis and growth hormone and insulin-like growth factor I secretion in intact adult male rats. Endocrinology. vol 137. issue 1. 1996-02-05. PMID:8536627. |
whereas central administration of npy strongly stimulates feeding in satiated animals, diet restriction or other unfavorable metabolic situations, such as diabetes, produce enhanced npy gene expression and npy release in the hypothalamus. |
1996-02-05 |
2023-08-12 |
rat |