| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| François P Pralong, Christine Gonzales, Marie-Jeanne Voirol, Richard D Palmiter, Hans-R Brunner, Rolf C Gaillard, Josiane Seydoux, Thierry Pedrazzin. The neuropeptide Y Y1 receptor regulates leptin-mediated control of energy homeostasis and reproductive functions. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 16. issue 7. 2002-05-06. PMID:11978737. |
to evaluate the importance of the npy y1 and y5 receptors in the downstream pathways modulated by leptin and controlling energy metabolism as well as the activity of the gonadotrope axis, we studied the effects of leptin administration on food intake and reproductive functions in mice deficient for the expression of either the y1 or the y5 receptor. |
2002-05-06 |
2023-08-12 |
mouse |
| François P Pralong, Christine Gonzales, Marie-Jeanne Voirol, Richard D Palmiter, Hans-R Brunner, Rolf C Gaillard, Josiane Seydoux, Thierry Pedrazzin. The neuropeptide Y Y1 receptor regulates leptin-mediated control of energy homeostasis and reproductive functions. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 16. issue 7. 2002-05-06. PMID:11978737. |
results point to a crucial role for the npy y1 receptor in mediating the npy pathways situated downstream of leptin actions and controlling food intake, the onset of puberty, and the maintenance of reproductive functions. |
2002-05-06 |
2023-08-12 |
mouse |
| Barbara Woodside, Christian Beaulé, Christine Laua. Chronic neuropeptide Y infusion during lactation suppresses pup growth and reduces the length of lactational infertility in rats. Hormones and behavior. vol 41. issue 1. 2002-05-01. PMID:11863384. |
effects on food intake; female body weight; and, where appropriate, litter weight and length of lactational diestrus were compared between npy and vehicle-treated females. |
2002-05-01 |
2023-08-12 |
rat |
| Barbara Woodside, Christian Beaulé, Christine Laua. Chronic neuropeptide Y infusion during lactation suppresses pup growth and reduces the length of lactational infertility in rats. Hormones and behavior. vol 41. issue 1. 2002-05-01. PMID:11863384. |
as expected npy infusion produced a robust increase in body weight and food intake in nonlactating females that was accompanied by a suppression of cyclicity. |
2002-05-01 |
2023-08-12 |
rat |
| Timothy H Moran, Pikki Lee, Ellen E Ladenheim, Gary J Schwart. Responsivity to NPY and melanocortins in obese OLETF rats lacking CCK-A receptors. Physiology & behavior. vol 75. issue 3. 2002-04-30. PMID:11897267. |
in order to determine whether alterations in sensitivity to central peptides involved in overall feeding control may contribute to the hyperphagia and obesity in oletf rats, we assessed oletf and leto rats feeding responses to lateral ventricular infusions of npy (1 and 3.2 nmol), the melanocortin 3/4 agonist mtii (0.1 and 0.32 nmol) and the melanocortin receptor antagonist shu-9119 (0.25 and 0.5 nmol). |
2002-04-30 |
2023-08-12 |
rat |
| Timothy H Moran, Pikki Lee, Ellen E Ladenheim, Gary J Schwart. Responsivity to NPY and melanocortins in obese OLETF rats lacking CCK-A receptors. Physiology & behavior. vol 75. issue 3. 2002-04-30. PMID:11897267. |
at a 3-h time point, npy increased food intake in both oletf and leto rats. |
2002-04-30 |
2023-08-12 |
rat |
| A Gładysz, P Krejci, J Simůnek, J Polkowsk. Effects of central infusions of neuropeptide Y on the somatotropic axis in sheep fed on two levels of protein. Acta neurobiologiae experimentalis. vol 61. issue 4. 2002-04-16. PMID:11905147. |
obtained results suggest that stimulatory effect of restricted feeding and/or npy action on gh secretion can be due to attenuated ss output. |
2002-04-16 |
2023-08-12 |
Not clear |
| Teruhiko Shimokawa, Monica V Kumar, M Daniel Lan. Effect of a fatty acid synthase inhibitor on food intake and expression of hypothalamic neuropeptides. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 1. 2002-04-15. PMID:11756683. |
in lean mice, c75 rapidly and almost completely blocked food intake and prevented fasting-induced up-regulation of hypothalamic agrp and npy mrnas, as well as down-regulation of cart and pomc mrnas. |
2002-04-15 |
2023-08-12 |
mouse |
| Yuwaraj K Narnaware, Richard E Pete. Influence of diet composition on food intake and neuropeptide Y (NPY) gene expression in goldfish brain. Regulatory peptides. vol 103. issue 2-3. 2002-04-05. PMID:11786146. |
influence of diet composition on food intake and neuropeptide y (npy) gene expression in goldfish brain. |
2002-04-05 |
2023-08-12 |
Not clear |
| Yuwaraj K Narnaware, Richard E Pete. Influence of diet composition on food intake and neuropeptide Y (NPY) gene expression in goldfish brain. Regulatory peptides. vol 103. issue 2-3. 2002-04-05. PMID:11786146. |
feeding diets with different protein contents for 1 or 4 weeks did not influence npy gene expression in goldfish brain. |
2002-04-05 |
2023-08-12 |
Not clear |
| G J Morton, M W Schwart. The NPY/AgRP neuron and energy homeostasis. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. vol 25 Suppl 5. 2002-04-05. PMID:11840217. |
these neurons make peptides that potently stimulate food intake not only by increasing neuropeptide y (npy) signaling, but by reducing melanocortin signaling via the release of agouti-related peptide (agrp), an endogenous melanocortin 3/4 receptor antagonist. |
2002-04-05 |
2023-08-12 |
Not clear |
| S Röjdmark, J Calissendorff, K Brisma. Alcohol ingestion decreases both diurnal and nocturnal secretion of leptin in healthy individuals. Clinical endocrinology. vol 55. issue 5. 2002-03-26. PMID:11894976. |
neuropeptide y (npy) stimulates appetite and increases food intake. |
2002-03-26 |
2023-08-12 |
human |
| B Beck, A Stricker-Krongrad, A Burlet, F Cumin, C Burle. Plasma leptin and hypothalamic neuropeptide Y and galanin levels in Long-Evans rats with marked dietary preferences. Nutritional neuroscience. vol 4. issue 1. 2002-03-19. PMID:11842875. |
npy concentrations were 23% lower (p <.02) in carbohydrate-preferring (cp) than in fat-preferring (fp) rats in the parvocellular part of the paraventricular nucleus (pvn), which is one of the main areas involved in the regulation of feeding behavior. |
2002-03-19 |
2023-08-12 |
rat |
| Dana K Sindelar, Paul Mystkowski, Donald J Marsh, Richard D Palmiter, Michael W Schwart. Attenuation of diabetic hyperphagia in neuropeptide Y--deficient mice. Diabetes. vol 51. issue 3. 2002-03-15. PMID:11872679. |
the combined effects of increased hypothalamic signaling by neuropeptide y (npy) and decreased signaling by melanocortins are hypothesized to stimulate food intake when body fat stores are depleted. |
2002-03-15 |
2023-08-12 |
mouse |
| Dana K Sindelar, Paul Mystkowski, Donald J Marsh, Richard D Palmiter, Michael W Schwart. Attenuation of diabetic hyperphagia in neuropeptide Y--deficient mice. Diabetes. vol 51. issue 3. 2002-03-15. PMID:11872679. |
in npy(+/+) mice, stz-induced diabetes increased mean daily food intake to plateau values 50% above baseline intake (+2.0 +/- 0.6 g/day; p < or = 0.05), an effect that was not seen in stz-treated npy(--/--) mice (+0.8 +/- 0.1 g/day; ns), despite comparably elevated levels of plasma glucose and comparably decreased levels of body weight, fat content, and plasma leptin. |
2002-03-15 |
2023-08-12 |
mouse |
| Dana K Sindelar, Paul Mystkowski, Donald J Marsh, Richard D Palmiter, Michael W Schwart. Attenuation of diabetic hyperphagia in neuropeptide Y--deficient mice. Diabetes. vol 51. issue 3. 2002-03-15. PMID:11872679. |
unlike the impaired feeding response to uncontrolled diabetes, npy(--/--) mice exhibit intact hyperphagic responses to fasting (erickson et al. |
2002-03-15 |
2023-08-12 |
mouse |
| Dana K Sindelar, Paul Mystkowski, Donald J Marsh, Richard D Palmiter, Michael W Schwart. Attenuation of diabetic hyperphagia in neuropeptide Y--deficient mice. Diabetes. vol 51. issue 3. 2002-03-15. PMID:11872679. |
we conclude that npy is required for both the increase of food intake and the decrease of hypothalamic pomc gene expression induced by uncontrolled diabetes. |
2002-03-15 |
2023-08-12 |
mouse |
| Dana K Sindelar, Paul Mystkowski, Donald J Marsh, Richard D Palmiter, Michael W Schwart. Attenuation of diabetic hyperphagia in neuropeptide Y--deficient mice. Diabetes. vol 51. issue 3. 2002-03-15. PMID:11872679. |
therefore, central nervous system melanocortin signaling appears to be suppressed more effectively by fasting than by uncontrolled diabetes, which provides a plausible explanation for differences in the feeding response to these two stimuli in mice lacking npy. |
2002-03-15 |
2023-08-12 |
mouse |
| Carolyn E Huntington, Neil F Shay, Eric Grouzmann, Linda M Arseneau, J Lee Beverl. Zinc status affects neurotransmitter activity in the paraventricular nucleus of rats. The Journal of nutrition. vol 132. issue 2. 2002-03-05. PMID:11823589. |
the activities of the ne and npy systems in the pvn were altered in rats fed a zinc-deficient diet; however, it is unclear whether the disruption in the ne and npy neural systems in the pvn results in the altered feeding behavior accompanying zinc deficiency. |
2002-03-05 |
2023-08-12 |
rat |
| Nina Pronchuk, Annette G Beck-Sickinger, William F Colmer. Multiple NPY receptors Inhibit GABA(A) synaptic responses of rat medial parvocellular effector neurons in the hypothalamic paraventricular nucleus. Endocrinology. vol 143. issue 2. 2002-02-28. PMID:11796508. |
we have recently shown that npy and alpha-melanocyte-stimulating hormone, which potently induce or inhibit feeding, respectively, have opposing modulatory actions on gabaergic synapses in the medial parvocellular region of the paraventricular hypothalamic nucleus (mppvn). |
2002-02-28 |
2023-08-12 |
rat |