| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Bari, A Dec, A W Lee, J Lee, D Song, E Dale, J Peterson, S Zorn, X Huang, B Campbell, T W Robbins, A R Wes. Enhanced inhibitory control by neuropeptide Y Y5 receptor blockade in rats. Psychopharmacology. vol 232. issue 5. 2015-11-05. PMID:25194952. |
research on the effects of npy in the central nervous system has focused on food intake control and affective processes, but growing evidence of npy involvement in attention-deficit/hyperactivity disorder (adhd) and other psychiatric conditions motivated the present study. |
2015-11-05 |
2023-08-13 |
rat |
| Udval Sedbazar, Enkh-Amar Ayush, Yuko Maejima, Toshihiko Yad. Neuropeptide Y and α-melanocyte-stimulating hormone reciprocally regulate nesfatin-1 neurons in the paraventricular nucleus of the hypothalamus. Neuroreport. vol 25. issue 18. 2015-10-27. PMID:25383463. |
in the hypothalamic feeding center, the second-order neurons in pvn are extensively projected by the first-order neurons in the arcuate nucleus (arc), the representatives of which are orexigenic neuropeptide y (npy) and anorexigenic α-melanocyte-stimulating hormone (α-msh) neurons. |
2015-10-27 |
2023-08-13 |
Not clear |
| Udval Sedbazar, Enkh-Amar Ayush, Yuko Maejima, Toshihiko Yad. Neuropeptide Y and α-melanocyte-stimulating hormone reciprocally regulate nesfatin-1 neurons in the paraventricular nucleus of the hypothalamus. Neuroreport. vol 25. issue 18. 2015-10-27. PMID:25383463. |
these data show that npy inhibits and α-msh activates pvn nesfatin-1/nucb2 neurons, presenting dual and reciprocal neuro-circuits from arc to pvn, possibly contributing toward the balanced regulation of feeding. |
2015-10-27 |
2023-08-13 |
Not clear |
| María J Ríos-Lugo, Vanesa Jiménez-Ortega, Pilar Cano-Barquilla, Pilar Fernández Mateos, Eduardo J Spinedi, Daniel P Cardinali, Ana I Esquifin. Melatonin counteracts changes in hypothalamic gene expression of signals regulating feeding behavior in high-fat fed rats. Hormone molecular biology and clinical investigation. vol 21. issue 3. 2015-10-14. PMID:25719335. |
the objective of the present study performed in high-fat fed rats was to evaluate the activity of melatonin on gene expression of some medial basal hypothalamus (mbh) signals involved in feeding behavior regulation, including neuropeptide y (npy), proopiomelanocortin (pomc), prolactin-releasing peptide (prrp), leptin- and insulin-receptors (r) and insulin-r substrate (irs)-1 and -2. |
2015-10-14 |
2023-08-13 |
rat |
| Eun Ran Kim, Zhaofei Wu, Hao Sun, Yuanzhong Xu, Leandra R Mangieri, Yong Xu, Qingchun Ton. Hypothalamic Non-AgRP, Non-POMC GABAergic Neurons Are Required for Postweaning Feeding and NPY Hyperphagia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 29. 2015-10-07. PMID:26203139. |
given the limited knowledge on postweaning feeding, our results are significant in identifying gaba release from a major subset of less appreciated hypothalamic neurons as a key mediator for postweaning feeding and npy hyperphagia, and the pvh as one major downstream site that contributes significantly to the gaba action. |
2015-10-07 |
2023-08-13 |
mouse |
| Maria Fernanda Condes Areias, Patricia Oliveira Prad. Mechanisms of insulin resistance in the amygdala: influences on food intake. Behavioural brain research. vol 282. 2015-09-21. PMID:25601576. |
the inhibition of er stress ameliorates insulin action/signaling, increases oxytocin and decreases npy gene expression in the amygdala of high fat feeding rodents. |
2015-09-21 |
2023-08-13 |
human |
| Laura A Nelson, Elizabeth R Gilbert, Mark A Clin. Effects of dietary macronutrient composition on exogenous neuropeptide Y's stimulation of food intake in chicks. Neuroscience letters. vol 591. 2015-09-15. PMID:25681626. |
chicks that consumed the high carbohydrate and protein diets had a non-dose dependent similar magnitude of increased food intake after npy injection, but those on the high fat diet had a dose dependent food intake increase. |
2015-09-15 |
2023-08-13 |
Not clear |
| Laura A Nelson, Elizabeth R Gilbert, Mark A Clin. Effects of dietary macronutrient composition on exogenous neuropeptide Y's stimulation of food intake in chicks. Neuroscience letters. vol 591. 2015-09-15. PMID:25681626. |
however, when chicks were raised on the high carbohydrate and then switched to high fat, npy injection caused a sustaining increase in cumulative food intake that lasted the entire observation period. |
2015-09-15 |
2023-08-13 |
Not clear |
| Laura A Nelson, Elizabeth R Gilbert, Mark A Clin. Effects of dietary macronutrient composition on exogenous neuropeptide Y's stimulation of food intake in chicks. Neuroscience letters. vol 591. 2015-09-15. PMID:25681626. |
these results suggest that npy has selective effects on consumption of carbohydrate, fat and protein in chicks, and that diet in turn affects the npy-mediated response in food intake, with a high fat diet enhancing npy sensitivity that is associated with a greater magnitude and duration of feeding response. |
2015-09-15 |
2023-08-13 |
Not clear |
| Laura A Nelson, Elizabeth R Gilbert, Mark A Clin. Effects of dietary macronutrient composition on exogenous neuropeptide Y's stimulation of food intake in chicks. Neuroscience letters. vol 591. 2015-09-15. PMID:25681626. |
finally, these results reinforce that npy increases food intake independent of diet. |
2015-09-15 |
2023-08-13 |
Not clear |
| S D Hewagalamulage, I J Clarke, I R Young, A Rao, B A Henr. High cortisol response to adrenocorticotrophic hormone identifies ewes with reduced melanocortin signalling and increased propensity to obesity. Journal of neuroendocrinology. vol 27. issue 1. 2015-09-08. PMID:25315658. |
infusion of these doses of npy, mch or orexin did not stimulate food intake in meal-fed ewes, although αmsh reduced (p < 0.01) food intake in lr only. |
2015-09-08 |
2023-08-13 |
Not clear |
| S D Hewagalamulage, I J Clarke, I R Young, A Rao, B A Henr. High cortisol response to adrenocorticotrophic hormone identifies ewes with reduced melanocortin signalling and increased propensity to obesity. Journal of neuroendocrinology. vol 27. issue 1. 2015-09-08. PMID:25315658. |
feeding, npy increased (p < 0.001) food intake in both groups but αmsh was only effective in lr (p < 0.05). |
2015-09-08 |
2023-08-13 |
Not clear |
| Dong-Yih Kuo, Pei-Ni Chen, Yih-Shou Hsie. Targeting oxidative stress in the hypothalamus: the effect of transcription factor STAT3 knockdown on endogenous antioxidants-mediated appetite control. Archives of toxicology. vol 89. issue 1. 2015-09-04. PMID:24792324. |
feeding, body weight, and npy decreased with the biggest reduction on day 2 during ppa treatment. |
2015-09-04 |
2023-08-13 |
rat |
| Magalie Thierry, Bruno Pasquis, Bénédicte Buteau, Cynthia Fourgeux, Doulaye Dembele, Laurent Leclere, Ségolène Gambert-Nicot, Niyazi Acar, Alain M Bron, Catherine P Creuzot-Garcher, Lionel Bretillo. Early adaptive response of the retina to a pro-diabetogenic diet: Impairment of cone response and gene expression changes in high-fructose fed rats. Experimental eye research. vol 135. 2015-08-24. PMID:25912194. |
rt-qpcr analysis confirmed the down regulation of crystallins, npy, nid1 and optc genes after 3 days of fructose feeding, and up regulation of end2. |
2015-08-24 |
2023-08-13 |
rat |
| Hélène Volkof. In vitro assessment of interactions between appetite-regulating peptides in brain of goldfish (Carassius auratus). Peptides. vol 61. 2015-07-29. PMID:25219945. |
in order to better understand the interactions between appetite-related peptides, the effects of in vitro treatments of hindbrain, forebrain and hypothalamus--a major feeding regulating area--fragments with mch, apelin and orexin on the expression of mch, apelin, orexin, cart (forms 1 and 2) and npy were assessed. |
2015-07-29 |
2023-08-13 |
Not clear |
| Y-S Hsieh, P-N Chen, C-H Yu, D-Y Ku. Central dopamine action modulates neuropeptide-controlled appetite via the hypothalamic PI3K/NF-κB-dependent mechanism. Genes, brain, and behavior. vol 13. issue 8. 2015-07-23. PMID:25160767. |
moreover, mc4r, pi3k, pakt and nf-κb increased with the maximum response on day 2, which was consistent with the response of feeding behavior, but was opposite to the expression of npy. |
2015-07-23 |
2023-08-13 |
rat |
| b' Jelena Roganovi\\xc4\\x87, Nina Petrovi\\xc4\\x87, Ljiljana Djuki\\xc4\\x8. Effect of neuropeptide Y on norepinephrine-induced constriction in the rabbit facial artery after carotid artery occlusion. Vojnosanitetski pregled. vol 71. issue 6. 2015-07-16. PMID:25039112.' |
the aim of this study was to investigate the influence of carotid artery occlusion (10, 30 and 60 min) on vascular effects of norepinephrine (nor) and neuropeptide y (npy) in the isolated glandular branch of the rabbit facial artery, the main feeding artery for the submandibular gland. |
2015-07-16 |
2023-08-13 |
rabbit |
| Christopher J Lelliott, Andrea Ahnmark, Therese Admyre, Ingela Ahlstedt, Lorraine Irving, Feenagh Keyes, Laurel Patterson, Michael B Mumphrey, Mikael Bjursell, Tracy Gorman, Mohammad Bohlooly-Y, Andrew Buchanan, Paula Harrison, Tristan Vaughan, Hans-Rudolf Berthoud, Daniel Lindé. Monoclonal antibody targeting of fibroblast growth factor receptor 1c ameliorates obesity and glucose intolerance via central mechanisms. PloS one. vol 9. issue 11. 2015-07-13. PMID:25427253. |
in addition, r1c mab did not change hypothalamic mrna expression levels of agrp, cart, pomc, npy, crh, mch, or orexin, suggesting that r1c mab could cause food intake inhibition and body weight loss via other mechanisms in the brain. |
2015-07-13 |
2023-08-13 |
mouse |
| John T Garretson, Brett J W Teubner, Kevin L Grove, Almira Vazdarjanova, Vitaly Ryu, Timothy J Bartnes. Peroxisome proliferator-activated receptor γ controls ingestive behavior, agouti-related protein, and neuropeptide Y mRNA in the arcuate hypothalamus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 11. 2015-06-15. PMID:25788674. |
we tested the following: (1) how rosi and/or gw9662 (2-chloro-5-nitro-n-phenylbenzamide; pparγ antagonist) injected intraperitoneally or into the third ventricle (3v) affected siberian hamster feeding behaviors; (2) whether food deprivation (fd) co-increases agouti-related protein (agrp) and pparγ mrna expression in siberian hamsters and mice; (3) whether intraperitoneally administered rosi increases agrp and npy in ad libitum-fed animals; (4) whether intraperitoneally administered pparγ antagonism blocks fd-induced increases in agrp and npy; and finally, (5) whether intraperitoneally administered pparγ modulation affects plasma ghrelin. |
2015-06-15 |
2023-08-13 |
mouse |
| A W Smith, O K Rønnekleiv, M J Kell. Gq-mER signaling has opposite effects on hypothalamic orexigenic and anorexigenic neurons. Steroids. vol 81. 2015-05-26. PMID:24269736. |
two populations of cells within the hypothalamus exert opposite actions on food intake: proopiomelanocortin (pomc) neurons decrease it, while neuropeptide y (npy)/agouti-related peptide (agrp) neurons increase it. |
2015-05-26 |
2023-08-12 |
Not clear |