Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Min Long, Jiyin Zhou, Dandan Li, Lu Zheng, Zihui Xu, Shiwen Zho. Long-Term Over-Expression of Neuropeptide Y in Hypothalamic Paraventricular Nucleus Contributes to Adipose Tissue Insulin Resistance Partly via the Y5 Receptor. PloS one. vol 10. issue 5. 2016-04-18. PMID:25993471. |
npy increased food intake, but did not change blood glucose, glycated hemoglobin a1c (hba1c) or lipid levels. |
2016-04-18 |
2023-08-13 |
rat |
H Wang, J Ji, Y Yu, X Wei, S Chai, D Liu, D Huang, Q Li, Z Dong, X Xia. Neonatal Overfeeding in Female Mice Predisposes the Development of Obesity in their Male Offspring via Altered Central Leptin Signalling. Journal of neuroendocrinology. vol 27. issue 7. 2016-03-29. PMID:25855235. |
we examined body weight, daily food intake, leptin responsiveness and the number of positive neurones for phosphorylated-signal transducer and activator of transcription 3 (pstat3) along with neuropeptide y (npy) in the arcuate nucleus of the hypothalamus (arh) and npy in the nucleus tractus solitarius (nts) of the brain stem. |
2016-03-29 |
2023-08-13 |
mouse |
Jiamei Lian, Michael De Santis, Meng He, Chao Den. Risperidone-induced weight gain and reduced locomotor activity in juvenile female rats: The role of histaminergic and NPY pathways. Pharmacological research. vol 95-96. 2016-03-21. PMID:25782398. |
consistently, risperidone significantly elevated mrna expression of hypothalamic h1r, neuropeptide y (npy), and agouti-related peptide (agrp) compared to controls, and h1r and npy levels were correlated with risperidone enhanced weight gain and food intake in the female juvenile rats. |
2016-03-21 |
2023-08-13 |
rat |
Kentaro Ito, Mohammad A Bahry, Yang Hui, Mitsuhiro Furuse, Vishwajit S Chowdhur. Acute heat stress up-regulates neuropeptide Y precursor mRNA expression and alters brain and plasma concentrations of free amino acids in chicks. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 187. 2016-03-21. PMID:25933935. |
the induction of npy and asip expression and the alteration of some free amino acids during ht suggest that these changes can be the results or causes the suppression of food intake. |
2016-03-21 |
2023-08-13 |
Not clear |
Yih-Shou Hsieh, Pei-Ni Chen, Ching-Han Yu, Chia-Hui Chen, Tsung-Ta Tsai, Dong-Yih Ku. Involvement of oxidative stress in the regulation of NPY/CART-mediated appetite control in amphetamine-treated rats. Neurotoxicology. vol 48. 2016-02-23. PMID:25825358. |
changes in food intake and expression levels of hypothalamic npy, cart, gst, and gp were examined and compared. |
2016-02-23 |
2023-08-13 |
rat |
Yih-Shou Hsieh, Pei-Ni Chen, Ching-Han Yu, Chia-Hui Chen, Tsung-Ta Tsai, Dong-Yih Ku. Involvement of oxidative stress in the regulation of NPY/CART-mediated appetite control in amphetamine-treated rats. Neurotoxicology. vol 48. 2016-02-23. PMID:25825358. |
results showed that, in amph-treated rats, (1) food intake and npy expression decreased, while cart, gst, and gp expression increased; (2) npy knockdown in the brain enhanced the decrease in npy and the increases in cart, gst, and gp expression; and (3) central inhibition of reactive oxygen species production decreased gst and gp and modulated amph anorexia and the expression levels of npy and cart. |
2016-02-23 |
2023-08-13 |
rat |
Ateegh Al-Arabi, J F Andrew. The effect of neuropeptide y and norepinepherine on food intake and body weight - biomed 2010. Biomedical sciences instrumentation. vol 46. 2016-02-18. PMID:20467124. |
the functional significance in noradrenergic neurons has been related to the vasomotor effects of npy which complement and interact with ne which is known to have central and peripheral effects on resting metabolic rate (rmr), food intake and body weight of rats. |
2016-02-18 |
2023-08-12 |
rat |
Ateegh Al-Arabi, J F Andrew. The effect of neuropeptide y and norepinepherine on food intake and body weight - biomed 2010. Biomedical sciences instrumentation. vol 46. 2016-02-18. PMID:20467124. |
in warm environmental the combined treatment with ne and npy was the only treatment that caused significant reduction of total body weight by inhibiting food intake. |
2016-02-18 |
2023-08-12 |
rat |
Bogdan Galusca, Gaëtan Prévost, Natacha Germain, Isabelle Dubuc, Yiin Ling, Youssef Anouar, Bruno Estour, Nicolas Chartre. Neuropeptide Y and α-MSH circadian levels in two populations with low body weight: anorexia nervosa and constitutional thinness. PloS one. vol 10. issue 3. 2016-02-09. PMID:25798605. |
the npy/proopiomelanocortin (pomc) system plays a crucial role in the regulation of feeding behavior as npy is the most potent orexigenic neuropeptide identified so far and as the pomc-derived peptide α-msh drastically reduces food intake, and this peptidergic system has not been thoroughly studied in an. |
2016-02-09 |
2023-08-13 |
Not clear |
Shu-Chen Chu, Pei-Ni Chen, Ying-Jui Ho, Ching-Han Yu, Yih-Shou Hsieh, Dong-Yih Ku. Both neuropeptide Y knockdown and Y1 receptor inhibition modulate CART-mediated appetite control. Hormones and behavior. vol 67. 2016-01-12. PMID:25461972. |
rats were treated daily with amph for four days, and changes in feeding behavior and expression levels of npy, cart, and pomc were assessed and compared. |
2016-01-12 |
2023-08-13 |
rat |
Shu-Chen Chu, Pei-Ni Chen, Ying-Jui Ho, Ching-Han Yu, Yih-Shou Hsieh, Dong-Yih Ku. Both neuropeptide Y knockdown and Y1 receptor inhibition modulate CART-mediated appetite control. Hormones and behavior. vol 67. 2016-01-12. PMID:25461972. |
the results showed that both feeding behavior and npy expression decreased during amph treatment, with the biggest reduction occurring on day 2. |
2016-01-12 |
2023-08-13 |
rat |
M E Radler, B J Wright, F R Walker, M W Hale, S Ken. Calorie restriction increases lipopolysaccharide-induced neuropeptide Y immunolabeling and reduces microglial cell area in the arcuate hypothalamic nucleus. Neuroscience. vol 285. 2015-12-31. PMID:25446356. |
to determine if increased npy expression in the arc following cr was associated with changes in microglial activation, a set of brain sections from mice that were exposed to 50% cr or ad libitum feeding for 28 days before being injected with lps were immunostained for npy. |
2015-12-31 |
2023-08-13 |
mouse |
Zhu Wan-long, Wang Zheng-ku. Seasonal changes in body mass, serum leptin levels and hypothalamic neuropeptide gene expression in male Eothenomys olitor. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 184. 2015-12-30. PMID:25700741. |
seasonal changes in the following parameters were measured in male e. olitor, body mass, food intake, thermogenesis, enzyme activity, masses of tissues and organs, hormone concentrations and expression of hypothalamic arcuate nucleus energy balance genes including neuropeptide y (npy), agouti-related protein (agrp), pro-opiomelanocortin (pomc), and cocaine- and amphetamine-regulated transcript (cart). |
2015-12-30 |
2023-08-13 |
Not clear |
Prashanth Anamthathmakula, Maitrayee Sahu, Abhiram Sah. Evidence suggesting phosphodiesterase-3B regulation of NPY/AgRP gene expression in mHypoE-46 hypothalamic neurons. Neuroscience letters. vol 604. 2015-12-21. PMID:26254161. |
hypothalamic neurons expressing neuropeptide y (npy) and agouti related-protein (agrp) are critical regulators of feeding behavior and body weight, and transduce the action of many peripheral signals including leptin and insulin. |
2015-12-21 |
2023-08-13 |
Not clear |
Ayako Ushimura, Tadataka Tsuji, Susumu Tanaka, Mikihiko Kogo, Takashi Yamamot. Neuropeptide-Y modulates eating patterns and masticatory muscle activity in rats. Behavioural brain research. vol 278. 2015-12-15. PMID:25447304. |
the feeding time for 2 g pellets was shorter in npy-injected rats and resulted in an increased feeding rate, with more potent effects observed at 1 μg compared to 10 μg npy. |
2015-12-15 |
2023-08-13 |
rat |
Ayako Ushimura, Tadataka Tsuji, Susumu Tanaka, Mikihiko Kogo, Takashi Yamamot. Neuropeptide-Y modulates eating patterns and masticatory muscle activity in rats. Behavioural brain research. vol 278. 2015-12-15. PMID:25447304. |
the present study indicates that 1 μg npy administration promotes feeding behavior together with increased feeding rate and powerful jaw-closing muscle activity; whereas 10 μg npy administration lowers jaw-closing muscle activity during biting and produces mastication with shorter and more frequent feeding bouts than 1 μg npy. |
2015-12-15 |
2023-08-13 |
rat |
José K van den Heuvel, Kara Furman, Myrtille C R Gumbs, Leslie Eggels, Darren M Opland, Benjamin B Land, Sharon M Kolk, Nandakumar S Narayanan, Eric Fliers, Andries Kalsbeek, Ralph J DiLeone, Susanne E la Fleu. Neuropeptide Y activity in the nucleus accumbens modulates feeding behavior and neuronal activity. Biological psychiatry. vol 77. issue 7. 2015-11-30. PMID:25109664. |
expression of the npy y1 receptor (y1r) is highly concentrated in the nucleus accumbens (acb), a region important in the regulation of palatable feeding. |
2015-11-30 |
2023-08-13 |
Not clear |
Hideharu Kurita, Kai Y Xu, Yuko Maejima, Masanori Nakata, Katsuya Dezaki, Putra Santoso, Yifei Yang, Takeshi Arai, Darambazar Gantulga, Shinji Muroya, Alan K Lefor, Masafumi Kakei, Eiju Watanabe, Toshihiko Yad. Arcuate Na+,K+-ATPase senses systemic energy states and regulates feeding behavior through glucose-inhibited neurons. American journal of physiology. Endocrinology and metabolism. vol 309. issue 4. 2015-11-17. PMID:26081283. |
third ventricular injection of the nka inhibitor ouabain induced c-fos expression in agouti-related protein (agrp) neurons in arc and evoked neuropeptide y (npy)-dependent feeding. |
2015-11-17 |
2023-08-13 |
Not clear |
Verena Albert, Marion Cornu, Michael N Hal. mTORC1 signaling in Agrp neurons mediates circadian expression of Agrp and NPY but is dispensable for regulation of feeding behavior. Biochemical and biophysical research communications. vol 464. issue 2. 2015-11-17. PMID:26159924. |
mtorc1 signaling in agrp neurons mediates circadian expression of agrp and npy but is dispensable for regulation of feeding behavior. |
2015-11-17 |
2023-08-13 |
mouse |
Verena Albert, Marion Cornu, Michael N Hal. mTORC1 signaling in Agrp neurons mediates circadian expression of Agrp and NPY but is dispensable for regulation of feeding behavior. Biochemical and biophysical research communications. vol 464. issue 2. 2015-11-17. PMID:26159924. |
agrp-raptor ko mice displayed reduced, non-circadian expression of agrp and npy but normal feeding behavior and energy homeostasis on both normal and high fat diet. |
2015-11-17 |
2023-08-13 |
mouse |