| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jie Gao, Gangqiang Ding, Qi Li, Lingxiao Gong, Jian Huang, Yaxin San. Tibet kefir milk decreases fat deposition by regulating the gut microbiota and gene expression of Lpl and Angptl4 in high fat diet-fed rats. Food research international (Ottawa, Ont.). vol 121. 2020-09-21. PMID:31108749. |
likewise, tmk feeding down-regulated lpl gene expression in fat and angptl4 (angiopoietin-like protein-4, also known as fasting-induced adipose factor) gene expression in liver, and up-regulated angptl4 gene expression in fat. |
2020-09-21 |
2023-08-13 |
human |
| W Boontiam, Y K Hyun, B Jung, Y Y Ki. Effects of lysophospholipid supplementation to reduced energy, crude protein, and amino acid diets on growth performance, nutrient digestibility, and blood profiles in broiler chickens. Poultry science. vol 98. issue 12. 2020-04-14. PMID:31801309. |
feeding of 0.15% lpl had promising effects on digestibility of crude protein and ether extract compared with nc (p < 0.01 and p < 0.05, respectively). |
2020-04-14 |
2023-08-13 |
Not clear |
| Sara Baldassano, Lærke Smidt Gasbjerg, Hüsün Sheyma Kizilkaya, Mette Marie Rosenkilde, Jens Juul Holst, Bolette Hartman. Increased Body Weight and Fat Mass After Subchronic GIP Receptor Antagonist, but Not GLP-2 Receptor Antagonist, Administration in Rats. Frontiers in endocrinology. vol 10. 2020-02-25. PMID:31447774. |
body weight, food intake, body composition, plasma lipoprotein lipase (lpl), adipokines, triglycerides and the marker of bone resorption carboxy-terminal collagen crosslinks (ctx), were examined. |
2020-02-25 |
2023-08-13 |
rat |
| Elise Laperrousaz, Raphaël G Denis, Nadim Kassis, Cristina Contreras, Miguel López, Serge Luquet, Céline Cruciani-Guglielmacci, Christophe Magna. Lipoprotein Lipase Expression in Hypothalamus Is Involved in the Central Regulation of Thermogenesis and the Response to Cold Exposure. Frontiers in endocrinology. vol 9. 2019-11-20. PMID:29593657. |
lipoprotein lipase (lpl) is expressed in different areas of the brain, including the hypothalamus and plays an important role in neural control of the energy balance, including feeding behavior and metabolic fluxes. |
2019-11-20 |
2023-08-13 |
mouse |
| Eliza Christopoulou, Moses Elisaf, Theodosios Filippato. Effects of Angiopoietin-Like 3 on Triglyceride Regulation, Glucose Homeostasis, and Diabetes. Disease markers. vol 2019. 2019-07-17. PMID:30944669. |
suggested mechanisms for the implication of angptl3 in carbohydrate metabolism include the (i) increment of free fatty acids (ffas) owing to the enhancement of lipolysis in adipose tissue, which can induce peripheral as well as hepatic insulin resistance; (ii) promotion of ffa flux to white adipose tissue during feeding, leading to the attenuation of de novo lipogenesis and decreased glucose uptake and insulin sensitivity; (iii) induction of hypothalamic lpl activity in mice, which is highly expressed throughout the brain and is associated with enhanced brain lipid sensing, reduction of food intake, and inhibition of glucose production (however, the effects of angptl3 on hypothalamic lpl in humans need more clarification); and (iv) upregulation of angptl4 expression (owing to the plasma ffa increase), which possibly enhances insulin resistance due to the selective inhibition of lpl in white adipose tissue leading to ectopic lipid accumulation and insulin resistance. |
2019-07-17 |
2023-08-13 |
mouse |
| Katsuyuki Nakajima, Akira Tanak. Atherogenic postprandial remnant lipoproteins; VLDL remnants as a causal factor in atherosclerosis. Clinica chimica acta; international journal of clinical chemistry. vol 478. 2018-08-27. PMID:29307667. |
plasma lpl did not increase after food intake, which may have caused the partial hydrolysis of cm and vldl as well as the significant increase of rlp-tg in the postprandial plasma. |
2018-08-27 |
2023-08-13 |
Not clear |
| Katsuyuki Nakajima, Akira Tanak. Atherogenic postprandial remnant lipoproteins; VLDL remnants as a causal factor in atherosclerosis. Clinica chimica acta; international journal of clinical chemistry. vol 478. 2018-08-27. PMID:29307667. |
lpl was inversely correlated with the rlp particle size after food intake. |
2018-08-27 |
2023-08-13 |
Not clear |
| Wen Wu, Kai-Lun Liang, Bo Chen, Jie Su, Su-Hong Chen, Gui-Yuan Ly. [Effects of Mori Folium extract on diet-induced obesity mechanism in rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 42. issue 9. 2018-06-28. PMID:29082702. |
both high dose and low dose groups had no significant effect on the food intake and water intake; however, they could decrease levels of lpl in fat, up-regulate p-ampkα protein expression, down-regulate c/ebpα and pparγ protein expression, and reduce fat cell volume. |
2018-06-28 |
2023-08-13 |
rat |
| Antwi-Boasiako Oteng, Asmita Bhattacharya, Susanne Brodesser, Ling Qi, Nguan Soon Tan, Sander Kerste. Feeding Journal of lipid research. vol 58. issue 6. 2018-01-15. PMID:28412693. |
feeding angiopoietin-like 4 (angptl4) regulates plasma triglyceride levels by inhibiting lpl. |
2018-01-15 |
2023-08-13 |
mouse |
| Zahndra Diann Butt, Jessica Dalton Hackett, Hélène Volkof. Irisin in goldfish (Carassius auratus): Effects of irisin injections on feeding behavior and expression of appetite regulators, uncoupling proteins and lipoprotein lipase, and fasting-induced changes in FNDC5 expression. Peptides. vol 90. 2017-11-29. PMID:28219696. |
to examine the role of irisin on feeding and metabolism in fish, the effects of peripheral (intraperitoneal) injections of irisin on feeding behavior, glucose levels and the mrna expressions of appetite regulators (cocaine and amphetamine regulated transcript cart, agouti related protein agrp, orexin), ucps and lipoprotein lipase lpl and brain factors (brain-derived neurotrophic factor , bdnf and tyrosine hydroxylase th) were assessed in brain, white muscle and intestine. |
2017-11-29 |
2023-08-13 |
Not clear |
| Zahndra Diann Butt, Jessica Dalton Hackett, Hélène Volkof. Irisin in goldfish (Carassius auratus): Effects of irisin injections on feeding behavior and expression of appetite regulators, uncoupling proteins and lipoprotein lipase, and fasting-induced changes in FNDC5 expression. Peptides. vol 90. 2017-11-29. PMID:28219696. |
irisin injections (100ng/g) induced a decrease in food intake and increases in brain orexin, cart1 and cart2, ucp2, bdnf, muscle ucp2 and intestine lpl mrna expressions but did not affect blood glucose levels, brain agrp, th, ucp1, ucp3 and lpl or muscle ucp1, ucp3 and lpl expressions. |
2017-11-29 |
2023-08-13 |
Not clear |
| Hong Wang, Matthew D Taussig, Nicholas V DiPatrizio, Kimberley Bruce, Daniele Piomelli, Robert H Ecke. Obesity development in neuron-specific lipoprotein lipase deficient mice is not responsive to increased dietary fat content or change in fat composition. Metabolism: clinical and experimental. vol 65. issue 7. 2017-05-18. PMID:27282869. |
our findings suggest that neuronal lpl is involved in the regulation of body weight and composition in response to either the change in quantity (hf feeding) or quality (n-3 pufa-enriched) of dietary fat. |
2017-05-18 |
2023-08-13 |
mouse |
| W Boontiam, B Jung, Y Y Ki. Effects of lysophospholipid supplementation to lower nutrient diets on growth performance, intestinal morphology, and blood metabolites in broiler chickens. Poultry science. vol 96. issue 3. 2017-03-22. PMID:28201632. |
feeding lpl linearly improved growth performance, feed conversion ratio, ether extract, and protein digestibility. |
2017-03-22 |
2023-08-13 |
Not clear |
| Nobuyoshi Ishiyama, Kouji Sakamaki, Younosuke Shimomura, Kazuhiko Kotani, Kokoro Tsuzaki, Naoki Sakane, Kazuya Miyashita, Isao Fukamachi, Junji Kobayashi, Kimber L Stanhope, Peter J Havel, Keiko Kamachi, Akira Tanaka, Yoshiharu Tokita, Tetsuo Machida, Masami Murakami, Katsuyuki Nakajim. Lipoprotein lipase does not increase significantly in the postprandial plasma. Clinica chimica acta; international journal of clinical chemistry. vol 464. 2017-02-08. PMID:27908779. |
therefore, we have reexamined those relationships using newly developed lpl assay with the different kinds of food intake. |
2017-02-08 |
2023-08-13 |
Not clear |
| Ren Zhan. The ANGPTL3-4-8 model, a molecular mechanism for triglyceride trafficking. Open biology. vol 6. issue 4. 2016-12-26. PMID:27053679. |
our recent data that angptl8 negatively regulates lpl activity specifically in cardiac and skeletal muscles suggest an angptl3-4-8 model: feeding induces angptl8, activating the angptl8-angptl3 pathway, which inhibits lpl in cardiac and skeletal muscles, thereby making circulating tg available for uptake by wat, in which lpl activity is elevated owing to diminished angptl4; the reverse is true during fasting, which suppresses angptl8 but induces angptl4, thereby directing tg to muscles. |
2016-12-26 |
2023-08-13 |
Not clear |
| Zhiyao Fu, Abdul B Abou-Samra, Ren Zhan. A lipasin/Angptl8 monoclonal antibody lowers mouse serum triglycerides involving increased postprandial activity of the cardiac lipoprotein lipase. Scientific reports. vol 5. 2016-10-21. PMID:26687026. |
we propose the following model: feeding induces lipasin, activating the lipasin-angptl3 pathway, which inhibits lpl in cardiac and skeletal muscles to direct circulating tag to wat for storage; conversely, fasting induces angptl4, which inhibits lpl in wat to direct circulating tag to cardiac and skeletal muscles for oxidation. |
2016-10-21 |
2023-08-13 |
mouse |
| Tsuyoshi Uchiyama, Shoichi Tomono, Koichi Sato, Tetsuya Nakamura, Masahiko Kurabayashi, Fumikazu Okajim. Angiotensin II Reduces Lipoprotein Lipase Expression in Visceral Adipose Tissue via Phospholipase C β4 Depending on Feeding but Increases Lipoprotein Lipase Expression in Subcutaneous Adipose Tissue via c-Src. PloS one. vol 10. issue 10. 2016-06-10. PMID:26447765. |
in conclusion, angii reduces lpl expression through plcβ4, the expression of which is regulated by feeding in vat, whereas angii increases lpl expression in sat. |
2016-06-10 |
2023-08-13 |
Not clear |
| Hui Tao, Guangjun Chang, Tianle Xu, Huajian Zhao, Kai Zhang, Xiangzhen She. Feeding a High Concentrate Diet Down-Regulates Expression of ACACA, LPL and SCD and Modifies Milk Composition in Lactating Goats. PloS one. vol 10. issue 6. 2016-05-04. PMID:26086219. |
feeding a high concentrate diet down-regulates expression of acaca, lpl and scd and modifies milk composition in lactating goats. |
2016-05-04 |
2023-08-13 |
Not clear |
| Melissa A Babilonia-Rosa, Saskia B Nehe. Purification, cellular levels, and functional domains of lipase maturation factor 1. Biochemical and biophysical research communications. vol 450. issue 1. 2014-09-21. PMID:24909692. |
lipoprotein lipase (lpl), a dimeric enzyme, is the main lipase responsible for tg clearance from the blood after food intake. |
2014-09-21 |
2023-08-13 |
Not clear |
| Alexandre Picard, Claude Rouch, Nadim Kassis, Valentine S Moullé, Sophie Croizier, Raphaël G Denis, Julien Castel, Nicolas Coant, Kathryn Davis, Deborah J Clegg, Stephen C Benoit, Vincent Prévot, Sébastien Bouret, Serge Luquet, Hervé Le Stunff, Céline Cruciani-Guglielmacci, Christophe Magna. Hippocampal lipoprotein lipase regulates energy balance in rodents. Molecular metabolism. vol 3. issue 2. 2014-03-17. PMID:24634821. |
decreased lpl activity by either method led to increased body weight gain due to decreased locomotor activity and energy expenditure, concomitant with increased parasympathetic tone (unchanged food intake). |
2014-03-17 |
2023-08-12 |
mouse |